Metabolic engineering of Corynebacterium glutamicum for the de novo production of ethylene glycol from glucose

Metabolic Engineering

Volumn 33, Issue , 2016, Pages 12-18

  Chen, Zhen ^a,b   Huang, Jinhai ^a   Wu, Yao ^a   Liu, Dehua ^a,b  

^a TSINGHUA UNIVERSITY   (China)

^b Advanced Composite Materials Research Center   (China)

Author keywords

Ethylene glycol; Metabolic engineering; Pathway optimization; Serine

Indexed keywords

AMINO ACIDS; CARBOXYLATION; COMBINATORIAL OPTIMIZATION; ETHYLENE; ETHYLENE GLYCOL; GLUCOSE; METABOLISM; POLYOLS; SYNTHESIS (CHEMICAL);

BIOLOGICAL PROCESS; COMMODITY CHEMICALS; CORYNEBACTERIUM GLUTAMICUM; ENZYMATIC DEAMINATION; RENEWABLE FEEDSTOCKS; SERINE; SYNTHESIS PATHWAYS; WHITE BIOTECHNOLOGY;

METABOLIC ENGINEERING;

ETHYLENE GLYCOL; GLUCOSE; SERINE; BACTERIAL PROTEIN;

ARTICLE; BACTERIAL STRAIN; BIOLOGICAL PHENOMENA AND FUNCTIONS CONCERNING THE ENTIRE ORGANISM; BIOSYNTHESIS; CATALYSIS; CHEMICAL STRUCTURE; CORYNEBACTERIUM GLUTAMICUM; DEAMINATION; DECARBOXYLATION; ENZYME METABOLISM; METABOLIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; PHYSIOLOGY; PROCEDURES; SIGNAL TRANSDUCTION;

BACTERIAL PROTEINS; CORYNEBACTERIUM GLUTAMICUM; ETHYLENE GLYCOL; GLUCOSE; METABOLIC ENGINEERING; SERINE; SIGNAL TRANSDUCTION;

EID: 84947059859     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2015.10.013     Document Type: Article

References (43)

1. Baumgart M., Unthan S., Rückert C., Sivalingam J., Grünberger A., Kalinowski J., Bott M., Noack S., Frunzke J. Construction of a prophage-free variant of Corynebacterium glutamicum ATCC 13032 for use as a platform strain for basic research and industrial biotechnology. Appl. Environ. Microbiol. 2013, 79:6006-6015.
2. Blombach B., Riester T., Wieschalka S., Ziert C., Youn J.-W., Wendisch V.F., Eikmanns B.J. Corynebacterium glutamicum tailored for efficient isobutanol production. Appl. Environ. Microbiol. 2011, 77:3300-3310.
3. Bommareddy R.R., Chen Z., Rappert S., Zeng A. A de novo NADPH generation pathway for improving lysine production of Corynebacterium glutamicum by rational design of the coenzyme specificity of glyceraldehyde 3-phosphate dehydrogenase. Metab. Eng. 2014, 25:30-37.
4. Buschke N., Schröder H., Wittmann C. Metabolic engineering of Corynebacterium glutamicum for production of 1,5-diaminopentane from hemicellulose. Biotechnol. J. 2011, 6:306-317.
5. Chen Z., Zeng A.-P. Protein design in systems metabolic engineering for industrial strain development. Biotechnol. J. 2013, 8:523-533.
6. Chen Z., Wilmanns M., Zeng A.-P. Structural synthetic biotechnology: from molecular structure to predictable design for industrial strain development. Trends Biotechnol. 2010, 28:534-542.
7. Chen Z., Wu Y., Huang J.H., Liu D.H. Metabolic engineering of Klebsiella pneumoniae for the de novo production of 2-butanol as a potential biofuel. Bioresour. Technol. 2015, 197:260-265.
8. Chen Z., Meyer W., Rappert S., Sun J., Zeng A.-P. Coevolutionary analysis enabled rational deregulation of allosteric enzyme inhibition in Corynebacterium glutamicum for lysine production. Appl. Environ. Microbiol. 2011, 77:4352-4360.
9. Chen Z., Bommareddy R.R., Frank D., Rappert S., Zeng A.-P. Deregulation of feedback inhibition of phosphoenolpyruvate carboxylase for improved lysine production in Corynebacterium glutamicum. Appl. Environ. Microbiol. 2014, 80:1388-1393.
10. Davies D.D., Asker H. The enzymatic decarboxylation of hydroxypyruvate associated with purified pyruvate decarboxylase from wheat germ. Phytochemistry 1984, 24:231-234.
11. De la Plaza M., Fernández de Palencia P., Peláez C., Requena T. Biochemical and molecular characterization of alpha-ketoisovalerate decarboxylase, an enzyme involved in the formation of aldehydes from amino acids by Lactococcus lactis. FEMS Microbiol. Lett. 2004, 238:367-374.
12. Gibson D.G., Young L., Chuang R.-Y., Venter J.C., Hutchison C.a, Smith H.O. Enzymatic assembly of DNA molecules up to several hundred kilobases. Nat. Methods 2009, 6:343-345.
13. Gu P., Yang F., Su T., Li F., Li Y., Qi Q. Construction of an L-serine producing Escherichia coli via metabolic engineering. J. Ind. Microbiol. Biotechnol. 2014, 1-8.
14. Hasegawa S., Suda M., Uematsu K., Natsuma Y., Hiraga K., Jojima T., Inui M., Yukawa H. Engineering of Corynebacterium glutamicum for high-yield L-valine production under oxygen deprivation conditions. Appl. Environ. Microbiol. 2013, 79:1250-1257.
15. Hedrick J.L., Sallach H.J. Nonoxidative decarboxylation of hydroxypyruvate in mammalian systems. Arch. Biochem. Biophys. 1964, 105:261-269.
16. Isern N.G., Xue J., Rao J.V., Cort J.R., Ahring B.K. Novel monosaccharide fermentation products in Caldicellulosiruptor saccharolyticus identified using NMR spectroscopy. Biotechnol. Biofuels 2013, 6:47.
17. Kataoka K., Tanizawa K. Alteration of substrate specificity of leucine dehydrogenase by site-directed mutagenesis. J. Mol. Catal. B Enzym. 2003, 23:299-309.
18. Keilhauer C., Eggeling L., Sahm H. Isoleucine synthesis in Corynebacterium glutamicum: molecular analysis of the ilvB-ilvN-ilvC operon. J. Bacteriol. 1993, 175:5595-5603.
19. Lan E.I., Liao J.C. Microbial synthesis of n-butanol, isobutanol, and other higher alcohols from diverse resources. Bioresour. Technol. 2013, 135:339-349.
20. Lee C., Kim I., Lee J., Lee K.L., Min B., Park C. Transcriptional activation of the aldehyde reductase YqhD by YqhC and its implication in glyoxal metabolism of Escherichia coli K-12. J. Bacteriol. 2010, 192:4205-4214.
21. Liepman A.H., Olsen L.J. Peroxisomal alanine: glyoxylate aminotransferase (AGT1) is a photorespiratory enzyme with multiple substrates in Arabidopsis thaliana. Plant J. 2001, 25:487-498.
22. Litsanov B., Brocker M., Bott M. Toward homosuccinate fermentation: metabolic engineering of Corynebacterium glutamicum for anaerobic production of succinate from glucose and formate. Appl. Environ. Microbiol. 2012, 78:3325-3337.
23. Liu H., Lu T. Autonomous production of 1,4-butanediol via a de novo biosynthesis pathway in engineered Escherichia coli. Metab. Eng. 2015, 29:135-141.
24. Liu H., Ramos K.R.M., Valdehuesa K.N.G., Nisola G.M., Lee W.-K., Chung W.-J. Biosynthesis of ethylene glycol in Escherichia coli. Appl. Microbiol. Biotechnol. 2013, 97:3409-3417.
25. Nakamura C.E., Whited G.M. Metabolic engineering for the microbial production of 1,3-propanediol. Curr. Opin. Biotechnol. 2003, 14:454-459.
26. Narrod S.A., Jakoby W.B. Metabolism of ethanolamine. An ethanolamine oxidase. J. Biol. Chem. 1964, 239:2189-2193.
27. Niu W., Molefe M.N., Frost J.W. Microbial synthesis of the energetic material precursor 1,2,4-butanetriol. J. Am. Chem. Soc. 2003, 125:12998-12999.
28. Obradors N., Cabiscol E., Aguilar J., Ros J. Site-directed mutagenesis studies of the metal-binding center of the iron-dependent propanediol oxidoreductase from Escherichia coli. Eur. J. Biochem. 1998, 258:207-213.
29. Ota H., Tamezane H., Sasano Y., Hokazono E., Yasuda Y., Sakasegawa S., Imamura S., Tamura T., Osawa S. Enzymatic characterization of an amine oxidase from Arthrobacter sp. used to measure phosphatidylethanolamine. Biosci. Biotechnol. Biochem. 2008, 72:2732-2738.
30. Peters-Wendisch P., Netzer R., Eggeling L., Sahm H. 3-Phosphoglyceratedehydrogenase from Corynebacterium glutamicum: the C-terminal domain is not essential for activity but is required for inhibition by L-serine. Appl. Microbiol. Biotechnol. 2002, 60:437-441.
31. Roh J.H., Suzuki H., Azakami H., Yamashita M., Murooka Y., Kumagai H. Purification, characterization, and crystallization of monoamine oxidase from Escherichia coli K-12. Biosci. Biotechnol. Biochem. 1994, 58:1652-1656.
32. Rontein D., Nishida I., Tashiro G., Yoshioka K., Wu W.I., Voelker D.R., Basset G., Hanson A.D. Plants synthesize ethanolamine by direct decarboxylation of serine using a pyridoxal phosphate enzyme. J. Biol. Chem. 2001, 276:35523-35529.
33. Rytter J.V., Helmark S., Chen J., Lezyk M.J., Solem C., Jensen P.R. Synthetic promoter libraries for Corynebacterium glutamicum. Appl. Microbiol. Biotechnol. 2014, 98:2617-2623.
34. Schäfer A., Tauch A., Jäger W., Kalinowski J., Thierbach G., Pühler A. Small mobilizable multi-purpose cloning vectors derived from the Escherichia coli plasmids pK18 and pK19: selection of defined deletions in the chromosome of Corynebacterium glutamicum. Gene 1994, 145:69-73.
35. Stephanopoulos, G., Pereira, B., De Mey, M., Dugar, D., Avalos, J.L., 2013. Engineering Microbes And Metabolic Pathways for the Production of Ethylene Glycol. US 20130316416 A1.
36. Stolz M., Peters-Wendisch P., Etterich H., Gerharz T., Faurie R., Sahm H., Fersterra H., Eggeling L. Reduced folate supply as a key to enhanced L-serine production by Corynebacterium glutamicum. Appl. Environ. Microbiol. 2007, 73:750-755.
37. Tian J., Bryk R., Itoh M., Suematsu M., Nathan C. Variant tricarboxylic acid cycle in Mycobacterium tuberculosis: identification of α-ketoglutarate decarboxylase. Proc. Natl. Acad. Sci. USA 2005, 102:10670-10675.
38. Turnbull A.P., Baker P.J., Rice D.W. Analysis of the quaternary structure, substrate specificity, and catalytic mechanism of valine dehydrogenase. J. Biol. Chem. 1997, 272:25105-25111.
39. Yang C., Rodionov D.A., Rodionova I.A., Li X., Osterman A.L. Glycerate 2-kinase of Thermotoga maritima and genomic reconstruction of related metabolic pathways. J. Bacteriol. 2008, 190:1773-1782.
40. Yim H., Haselbeck R., Niu W., Pujol-Baxley C., Burgard A., Boldt J., Khandurina J., Trawick J.D., Osterhout R.E., Stephen R., Estadilla J., Teisan S., Schreyer H.B., Andrae S., Yang T.H., Lee S.Y., Burk M.J., Van Dien S. Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol. Nat. Chem. Biol. 2011, 7:445-452.
41. Zhang M., Yu Y. Dehydration of ethanol to ethylene. Ind. Eng. Chem. Res. 2013, 52:9505-9514.
42. Zhang Q., Lee J., Pandurangan S., Clarke M., Pajak A., Marsolais F. Characterization of Arabidopsis serine:glyoxylate aminotransferase, AGT1, as an asparagine aminotransferase. Phytochemistry 2013, 85:30-35.
43. Zhu Q., Zhang X., Luo Y., Guo W., Xu G., Shi J., Xu Z. l-Serine overproduction with minimization of by-product synthesis by engineered Corynebacterium glutamicum. Appl. Microbiol. Biotechnol. 2014, 99:1665-1673.