X-ray recordings reveal how a human disease-linked skeletal muscle α-actin mutation leads to contractile dysfunction

Journal of Structural Biology

Volumn 192, Issue 3, 2015, Pages 331-335

  Ochala, Julien ^a   Ravenscroft, Gianina ^b   McNamara, Elyshia ^b   Nowak, Kristen J ^b   Iwamoto, Hiroyuki ^c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c JAPAN SYNCHROTRON RADIATION RESEARCH INSTITUTE   (Japan)

Author keywords

Actin; Muscle disease; Myosin; Small angle X ray scattering

Indexed keywords

MUSCLE PROTEIN; MYOSIN; SKELETAL MUSCLE ALPHA ACTIN; UNCLASSIFIED DRUG; ACTIN; TROPOMYOSIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; MOLECULAR DYNAMICS; MOUSE; MUTATIONAL ANALYSIS; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SARCOMERE LENGTH; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION; AMINO ACID SUBSTITUTION; ANIMAL; GENETICS; HUMAN; METABOLISM; MUSCLE CONTRACTION; MUSCLE FIBRIL; MUSCLE WEAKNESS; MUTATION; PATHOLOGY; SKELETAL MUSCLE; TRANSGENIC MOUSE;

ACTINS; AMINO ACID SUBSTITUTION; ANIMALS; HUMANS; MICE; MICE, TRANSGENIC; MUSCLE CONTRACTION; MUSCLE WEAKNESS; MUSCLE, SKELETAL; MUTATION; MYOFIBRILS; MYOSINS; TROPOMYOSIN; X-RAY DIFFRACTION;

EID: 84947046685     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2015.09.008     Document Type: Article

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