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Volumn 28, Issue 8, 2015, Pages 928-937

Calcineurin inhibitor-sparing regimens based on mycophenolic acid after kidney transplantation

Author keywords

calcineurin inhibitors; kidney transplantation; minimization; mycophenolic acid; withdrawal

Indexed keywords

CALCINEURIN INHIBITOR; CYCLOSPORIN A; DACLIZUMAB; MYCOPHENOLIC ACID; STEROID; TACROLIMUS; IMMUNOSUPPRESSIVE AGENT;

EID: 84947038984     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/tri.12515     Document Type: Review
Times cited : (12)

References (41)
  • 1
    • 10844292763 scopus 로고    scopus 로고
    • Immunosuppressive drugs for kidney transplantation
    • Halloran PF,. Immunosuppressive drugs for kidney transplantation. N Engl J Med 2004; 351: 2715.
    • (2004) N Engl J Med , vol.351 , pp. 2715
    • Halloran, P.F.1
  • 2
    • 34248683938 scopus 로고    scopus 로고
    • Results of an international, randomized trial comparing glucose metabolism disorders and outcome with cyclosporine versus tacrolimus
    • Vincenti F, Friman S, Scheuermann E, et al,. Results of an international, randomized trial comparing glucose metabolism disorders and outcome with cyclosporine versus tacrolimus. Am J Transplant 2007; 7: 1506.
    • (2007) Am J Transplant , vol.7 , pp. 1506
    • Vincenti, F.1    Friman, S.2    Scheuermann, E.3
  • 4
    • 60649101659 scopus 로고    scopus 로고
    • Identifying specific causes of kidney allograft loss
    • El-Zoghby ZM, Stegall MD, Lager DJ, et al,. Identifying specific causes of kidney allograft loss. Am J Transplant 2009; 9: 527.
    • (2009) Am J Transplant , vol.9 , pp. 527
    • El-Zoghby, Z.M.1    Stegall, M.D.2    Lager, D.J.3
  • 6
    • 0042360213 scopus 로고    scopus 로고
    • Chronic renal failure after transplantation of a nonrenal organ
    • Ojo AO, Held PJ, Port FK, et al,. Chronic renal failure after transplantation of a nonrenal organ. N Engl J Med 2003; 349: 931.
    • (2003) N Engl J Med , vol.349 , pp. 931
    • Ojo, A.O.1    Held, P.J.2    Port, F.K.3
  • 7
    • 84904542658 scopus 로고    scopus 로고
    • Belatacept-based immunosuppression in de novo liver transplant recipients: 1-year experience from a phase II randomized study
    • Klintmalm GB, Feng S, Lake JR, et al,. Belatacept-based immunosuppression in de novo liver transplant recipients: 1-year experience from a phase II randomized study. Am J Transplant 2014; 14: 1817.
    • (2014) Am J Transplant , vol.14 , pp. 1817
    • Klintmalm, G.B.1    Feng, S.2    Lake, J.R.3
  • 8
    • 84947032895 scopus 로고    scopus 로고
    • Immunosuppressive minimization with MTOR inhibitors and belatacept
    • Diekmann F,. Immunosuppressive minimization with MTOR inhibitors and belatacept. Transpl Int 2015; 28: 921.
    • (2015) Transpl Int , vol.28 , pp. 921
    • Diekmann, F.1
  • 9
    • 0035344597 scopus 로고    scopus 로고
    • Chronic allograft nephropathy: Prospective randomised trial of cyclosporin withdrawal and mycophenolate mofetil or tacrolimus substitution
    • McGrath JS, Shehata M,. Chronic allograft nephropathy: Prospective randomised trial of cyclosporin withdrawal and mycophenolate mofetil or tacrolimus substitution. Transplant Proc 2001; 33: 2193.
    • (2001) Transplant Proc , vol.33 , pp. 2193
    • McGrath, J.S.1    Shehata, M.2
  • 10
    • 0035070048 scopus 로고    scopus 로고
    • Long-term impact of discontinued or reduced calcineurin inhibitor in patients with chronic allograft nephropathy
    • Weir MR, Ward MT, Blahut SA, et al,. Long-term impact of discontinued or reduced calcineurin inhibitor in patients with chronic allograft nephropathy. Kidney Int 2001; 59: 1567.
    • (2001) Kidney Int , vol.59 , pp. 1567
    • Weir, M.R.1    Ward, M.T.2    Blahut, S.A.3
  • 11
    • 4644277373 scopus 로고    scopus 로고
    • Late calcineurin inhibitor withdrawal as a strategy to prevent graft loss in patients with suboptimal kidney transplant function
    • Weir MR, Blahut S, Drachenburg C, et al,. Late calcineurin inhibitor withdrawal as a strategy to prevent graft loss in patients with suboptimal kidney transplant function. Am J Nephrol 2004; 24: 379.
    • (2004) Am J Nephrol , vol.24 , pp. 379
    • Weir, M.R.1    Blahut, S.2    Drachenburg, C.3
  • 12
    • 1942502227 scopus 로고    scopus 로고
    • Withdrawal of cyclosporine or tacrolimus after addition of mycophenolate mofetil in patients with chronic allograft nephropathy
    • Suwelack B, Gerhardt U, Hohage H,. Withdrawal of cyclosporine or tacrolimus after addition of mycophenolate mofetil in patients with chronic allograft nephropathy. Am J Transplant 2004; 4: 655.
    • (2004) Am J Transplant , vol.4 , pp. 655
    • Suwelack, B.1    Gerhardt, U.2    Hohage, H.3
  • 13
    • 14044252180 scopus 로고    scopus 로고
    • Mycophenolate mofetil substitution for cyclosporine a in renal transplant recipients with chronic progressive allograft dysfunction: The "creeping creatinine" study
    • Dudley C, Pohanka E, Riad H, et al,. Mycophenolate mofetil substitution for cyclosporine a in renal transplant recipients with chronic progressive allograft dysfunction: the "creeping creatinine" study. Transplantation 2005; 79: 466.
    • (2005) Transplantation , vol.79 , pp. 466
    • Dudley, C.1    Pohanka, E.2    Riad, H.3
  • 14
    • 4344695166 scopus 로고    scopus 로고
    • A randomized controlled trial of immunosuppression conversion for the treatment of chronic allograft nephropathy
    • Stoves J, Newstead CG, Baczkowski AJ, Owens G, Paraoan M, Hammad AQ,. A randomized controlled trial of immunosuppression conversion for the treatment of chronic allograft nephropathy. Nephrol Dial Transplant 2004; 19: 2113.
    • (2004) Nephrol Dial Transplant , vol.19 , pp. 2113
    • Stoves, J.1    Newstead, C.G.2    Baczkowski, A.J.3    Owens, G.4    Paraoan, M.5    Hammad, A.Q.6
  • 15
    • 33750033625 scopus 로고    scopus 로고
    • Impact of cyclosporine reduction with MMF: A randomized trial in chronic allograft dysfunction. The 'reference' study
    • Frimat L, Cassuto-Viguier E, Charpentier B, et al,. Impact of cyclosporine reduction with MMF: a randomized trial in chronic allograft dysfunction. The 'reference' study. Am J Transplant 2006; 6: 2725.
    • (2006) Am J Transplant , vol.6 , pp. 2725
    • Frimat, L.1    Cassuto-Viguier, E.2    Charpentier, B.3
  • 16
    • 79961028817 scopus 로고    scopus 로고
    • Long-term impact of cyclosporin reduction with MMF treatment in chronic allograft dysfunction: REFERENCE Study 3-year follow up
    • pii:
    • Frimat L, Cassuto-Viguier E, Provot F, et al,. Long-term impact of cyclosporin reduction with MMF treatment in chronic allograft dysfunction: REFERENCE Study 3-year follow up. J Transplant 2010; 2010: pii: 402750. doi: 10.1155/2010/402750.
    • (2010) J Transplant , vol.2010 , pp. 402750
    • Frimat, L.1    Cassuto-Viguier, E.2    Provot, F.3
  • 17
    • 0034662213 scopus 로고    scopus 로고
    • Randomized study on the conversion of treatment with cyclosporine to azathioprine or mycophenolate mofetil followed by dose reduction
    • Smak Gregoor PJ, van Gelder T, van Besouw NM, van der Mast BJ, Ijzermans JN, Weimar W,. Randomized study on the conversion of treatment with cyclosporine to azathioprine or mycophenolate mofetil followed by dose reduction. Transplantation 2000; 70: 143.
    • (2000) Transplantation , vol.70 , pp. 143
    • Smak Gregoor, P.J.1    Van Gelder, T.2    Van Besouw, N.M.3    Van Der Mast, B.J.4    Ijzermans, J.N.5    Weimar, W.6
  • 18
    • 0034144384 scopus 로고    scopus 로고
    • Mycophenolate mofetil monotherapy: An example of a safe nephrotoxicity/atherogenicity-free immunosuppressive maintenance regimen in a selected group of kidney-transplanted patients
    • Keunecke C, Rothenpieler U, Zanker B, et al,. Mycophenolate mofetil monotherapy: an example of a safe nephrotoxicity/atherogenicity-free immunosuppressive maintenance regimen in a selected group of kidney-transplanted patients. Transplant Proc 2000; 32: 6S.
    • (2000) Transplant Proc , vol.32 , pp. 6S
    • Keunecke, C.1    Rothenpieler, U.2    Zanker, B.3
  • 19
    • 0037184818 scopus 로고    scopus 로고
    • Cyclosporine withdrawal from a mycophenolate mofetil-containing immunosuppressive regimen in stable kidney transplant recipients: A randomized, controlled study
    • Abramowicz D, Manas D, Lao M, et al,. Cyclosporine withdrawal from a mycophenolate mofetil-containing immunosuppressive regimen in stable kidney transplant recipients: a randomized, controlled study. Transplantation 2002; 74: 1725.
    • (2002) Transplantation , vol.74 , pp. 1725
    • Abramowicz, D.1    Manas, D.2    Lao, M.3
  • 20
    • 27744527131 scopus 로고    scopus 로고
    • Cyclosporine withdrawal from a mycophenolate mofetil-containing immunosuppressive regimen: Results of a five-year, prospective, randomized study
    • Abramowicz D, Del Carmen Rial M, Vitko S, et al,. Cyclosporine withdrawal from a mycophenolate mofetil-containing immunosuppressive regimen: results of a five-year, prospective, randomized study. J Am Soc Nephrol 2005; 16: 2234.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2234
    • Abramowicz, D.1    Del Carmen Rial, M.2    Vitko, S.3
  • 21
    • 14544288351 scopus 로고    scopus 로고
    • Low-dose mycophenolate mofetil is an effective and safe treatment to permit phased reduction in calcineurin inhibitors in chronic allograft nephropathy
    • Afzali B, Shah S, Chowdhury P, O'Sullivan H, Taylor J, Goldsmith D,. Low-dose mycophenolate mofetil is an effective and safe treatment to permit phased reduction in calcineurin inhibitors in chronic allograft nephropathy. Transplantation 2005; 79: 304.
    • (2005) Transplantation , vol.79 , pp. 304
    • Afzali, B.1    Shah, S.2    Chowdhury, P.3    O'Sullivan, H.4    Taylor, J.5    Goldsmith, D.6
  • 22
    • 0038586444 scopus 로고    scopus 로고
    • A prospective, randomized clinical trial of cyclosporine reduction in stable patients greater than 12 months after renal transplantation
    • Pascual M, Curtis J, Delmonico FL, et al,. A prospective, randomized clinical trial of cyclosporine reduction in stable patients greater than 12 months after renal transplantation. Transplantation 2003; 75: 1501.
    • (2003) Transplantation , vol.75 , pp. 1501
    • Pascual, M.1    Curtis, J.2    Delmonico, F.L.3
  • 23
    • 77956238223 scopus 로고    scopus 로고
    • A 50% reduction in cyclosporine exposure in stable renal transplant recipients: Renal function benefits
    • Etienne I, Toupance O, Benichou J, et al,. A 50% reduction in cyclosporine exposure in stable renal transplant recipients: renal function benefits. Nephrol Dial Transplant 2010; 25: 3096.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 3096
    • Etienne, I.1    Toupance, O.2    Benichou, J.3
  • 24
    • 84859505163 scopus 로고    scopus 로고
    • A multicenter, randomized trial of increased mycophenolic acid dose using enteric-coated mycophenolate sodium with reduced tacrolimus exposure in maintenance kidney transplant recipients
    • Kamar N, Rostaing L, Cassuto E, et al,. A multicenter, randomized trial of increased mycophenolic acid dose using enteric-coated mycophenolate sodium with reduced tacrolimus exposure in maintenance kidney transplant recipients. Clin Nephrol 2012; 77: 126.
    • (2012) Clin Nephrol , vol.77 , pp. 126
    • Kamar, N.1    Rostaing, L.2    Cassuto, E.3
  • 25
    • 80052401457 scopus 로고    scopus 로고
    • Renal graft function and low-dose cyclosporine affect mycophenolic acid pharmacokinetics in kidney transplantation
    • Cortinovis M, Gotti E, Pradini S, Gaspari F, Perico N,. Renal graft function and low-dose cyclosporine affect mycophenolic acid pharmacokinetics in kidney transplantation. Transplantation 2011; 92: 550.
    • (2011) Transplantation , vol.92 , pp. 550
    • Cortinovis, M.1    Gotti, E.2    Pradini, S.3    Gaspari, F.4    Perico, N.5
  • 26
    • 0033770939 scopus 로고    scopus 로고
    • Avoidance of cyclosporine in renal transplantation: Effects of daclizumab, mycophenolate mofetil, and steroids
    • Tran HT, Acharya MK, McKay DB, et al,. Avoidance of cyclosporine in renal transplantation: effects of daclizumab, mycophenolate mofetil, and steroids. J Am Soc Nephrol 2000; 11: 1903.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 1903
    • Tran, H.T.1    Acharya, M.K.2    McKay, D.B.3
  • 27
    • 0035872742 scopus 로고    scopus 로고
    • Multicenter trial exploring calcineurin inhibitors avoidance in renal transplantation
    • Vincenti F, Ramos E, Brattstrom C, et al,. Multicenter trial exploring calcineurin inhibitors avoidance in renal transplantation. Transplantation 2001; 71: 1282.
    • (2001) Transplantation , vol.71 , pp. 1282
    • Vincenti, F.1    Ramos, E.2    Brattstrom, C.3
  • 28
    • 0345098542 scopus 로고    scopus 로고
    • Calcineurin inhibitor-free immunosuppression based on antithymocyte globulin and mycophenolate mofetil in cadaveric kidney transplantation: Results after 5 years
    • Grinyo JM, Gil-Vernet S, Cruzado JM, et al,. Calcineurin inhibitor-free immunosuppression based on antithymocyte globulin and mycophenolate mofetil in cadaveric kidney transplantation: results after 5 years. Transpl Int 2003; 16: 820.
    • (2003) Transpl Int , vol.16 , pp. 820
    • Grinyo, J.M.1    Gil-Vernet, S.2    Cruzado, J.M.3
  • 29
    • 21044443129 scopus 로고    scopus 로고
    • A calcineurin antagonist-free induction/maintenance strategy for immunosuppression in elderly recipients of renal allografts from elderly cadaver donors: Long-term results from a prospective single centre trial
    • Arbogast H, Huckelheim H, Schneeberger H, et al,. A calcineurin antagonist-free induction/maintenance strategy for immunosuppression in elderly recipients of renal allografts from elderly cadaver donors: long-term results from a prospective single centre trial. Clin Transplant 2005; 19: 309.
    • (2005) Clin Transplant , vol.19 , pp. 309
    • Arbogast, H.1    Huckelheim, H.2    Schneeberger, H.3
  • 30
    • 33747480956 scopus 로고    scopus 로고
    • Calcineurin inhibitor avoidance with daclizumab, mycophenolate mofetil, and prednisolone in DR-matched de novo kidney transplant recipients
    • Asberg A, Midtvedt K, Line PD, et al,. Calcineurin inhibitor avoidance with daclizumab, mycophenolate mofetil, and prednisolone in DR-matched de novo kidney transplant recipients. Transplantation 2006; 82: 62.
    • (2006) Transplantation , vol.82 , pp. 62
    • Asberg, A.1    Midtvedt, K.2    Line, P.D.3
  • 31
    • 45749089709 scopus 로고    scopus 로고
    • Calcineurin-inhibitor avoidance in elderly renal allograft recipients using ATG and basiliximab combined with mycophenolate mofetil
    • Guba M, Rentsch M, Wimmer CD, et al,. Calcineurin-inhibitor avoidance in elderly renal allograft recipients using ATG and basiliximab combined with mycophenolate mofetil. Transpl Int 2008; 21: 637.
    • (2008) Transpl Int , vol.21 , pp. 637
    • Guba, M.1    Rentsch, M.2    Wimmer, C.D.3
  • 32
    • 28444454862 scopus 로고    scopus 로고
    • Predictive factors of acute rejection after early cyclosporine withdrawal in renal transplant recipients who receive mycophenolate mofetil: Results from a prospective, randomized trial
    • Hazzan M, Labalette M, Copin MC, et al,. Predictive factors of acute rejection after early cyclosporine withdrawal in renal transplant recipients who receive mycophenolate mofetil: results from a prospective, randomized trial. J Am Soc Nephrol 2005; 16: 2509.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2509
    • Hazzan, M.1    Labalette, M.2    Copin, M.C.3
  • 33
    • 33748698619 scopus 로고    scopus 로고
    • Assessment of the risk of chronic allograft dysfunction after renal transplantation in a randomized cyclosporine withdrawal trial
    • Hazzan M, Buob D, Labalette M, et al,. Assessment of the risk of chronic allograft dysfunction after renal transplantation in a randomized cyclosporine withdrawal trial. Transplantation 2006; 82: 657.
    • (2006) Transplantation , vol.82 , pp. 657
    • Hazzan, M.1    Buob, D.2    Labalette, M.3
  • 34
    • 33847765065 scopus 로고    scopus 로고
    • Cyclosporine sparing with mycophenolate mofetil, daclizumab and corticosteroids in renal allograft recipients: The CAESAR Study
    • Ekberg H, Grinyo J, Nashan B, et al,. Cyclosporine sparing with mycophenolate mofetil, daclizumab and corticosteroids in renal allograft recipients: the CAESAR Study. Am J Transplant 2007; 7: 560.
    • (2007) Am J Transplant , vol.7 , pp. 560
    • Ekberg, H.1    Grinyo, J.2    Nashan, B.3
  • 35
    • 37349034394 scopus 로고    scopus 로고
    • Reduced exposure to calcineurin inhibitors in renal transplantation
    • Ekberg H, Tedesco-Silva H, Demirbas A, et al,. Reduced exposure to calcineurin inhibitors in renal transplantation. N Engl J Med 2007; 357: 2562.
    • (2007) N Engl J Med , vol.357 , pp. 2562
    • Ekberg, H.1    Tedesco-Silva, H.2    Demirbas, A.3
  • 36
    • 67651115805 scopus 로고    scopus 로고
    • The pharmacokinetics of mycophenolate mofetil in renal transplant recipients receiving standard-dose or low-dose cyclosporine, low-dose tacrolimus or low-dose sirolimus: The Symphony pharmacokinetic substudy
    • Grinyo JM, Ekberg H, Mamelok RD, et al,. The pharmacokinetics of mycophenolate mofetil in renal transplant recipients receiving standard-dose or low-dose cyclosporine, low-dose tacrolimus or low-dose sirolimus: the Symphony pharmacokinetic substudy. Nephrol Dial Transplant 2009; 24: 2269.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 2269
    • Grinyo, J.M.1    Ekberg, H.2    Mamelok, R.D.3
  • 37
    • 77955755249 scopus 로고    scopus 로고
    • Acute rejection in low-toxicity regimens: Clinical impact and risk factors in the Symphony study
    • Frei U, Daloze P, Vitko S, et al,. Acute rejection in low-toxicity regimens: clinical impact and risk factors in the Symphony study. Clin Transplant 2010; 24: 500.
    • (2010) Clin Transplant , vol.24 , pp. 500
    • Frei, U.1    Daloze, P.2    Vitko, S.3
  • 38
    • 67650938542 scopus 로고    scopus 로고
    • Calcineurin inhibitor minimization in the Symphony study: Observational results 3 years after transplantation
    • Ekberg H, Bernasconi C, Tedesco-Silva H, et al,. Calcineurin inhibitor minimization in the Symphony study: observational results 3 years after transplantation. Am J Transplant 2009; 9: 1876.
    • (2009) Am J Transplant , vol.9 , pp. 1876
    • Ekberg, H.1    Bernasconi, C.2    Tedesco-Silva, H.3
  • 39
    • 65649141573 scopus 로고    scopus 로고
    • Calcineurin inhibitor sparing with mycophenolate in kidney transplantation: A systematic review and meta-analysis
    • Moore J, Middleton L, Cockwell P, et al,. Calcineurin inhibitor sparing with mycophenolate in kidney transplantation: a systematic review and meta-analysis. Transplantation 2009; 87: 591.
    • (2009) Transplantation , vol.87 , pp. 591
    • Moore, J.1    Middleton, L.2    Cockwell, P.3
  • 40
    • 77955607610 scopus 로고    scopus 로고
    • Preexisting donor-specific HLA antibodies predict outcome in kidney transplantation
    • Lefaucheur C, Loupy A, Hill GS, et al,. Preexisting donor-specific HLA antibodies predict outcome in kidney transplantation. J Am Soc Nephrol 2010; 21: 1398.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1398
    • Lefaucheur, C.1    Loupy, A.2    Hill, G.S.3
  • 41
    • 0036154082 scopus 로고    scopus 로고
    • Open randomized trial comparing early withdrawal of either cyclosporine or mycophenolate mofetil in stable renal transplant recipients initially treated with a triple drug regimen
    • Schnuelle P, van der Heide JH, Tegzess A, et al,. Open randomized trial comparing early withdrawal of either cyclosporine or mycophenolate mofetil in stable renal transplant recipients initially treated with a triple drug regimen. J Am Soc Nephrol 2002; 13: 536.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 536
    • Schnuelle, P.1    Van Der Heide, J.H.2    Tegzess, A.3


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