-
1
-
-
33846230492
-
Clinical pharmacokinetics and pharmacodynamics of mycophenolate in solid organ transplant recipients
-
Staatz CE, Tett SE. Clinical pharmacokinetics and pharmacodynamics of mycophenolate in solid organ transplant recipients. Clin Pharmacokinet 2007; 46: 13.
-
(2007)
Clin Pharmacokinet
, vol.46
, pp. 13
-
-
Staatz, C.E.1
Tett, S.E.2
-
3
-
-
11144318750
-
Identification of the UDPglucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism
-
Picard N, Ratanasavanh D, Premaud A, et al. Identification of the UDPglucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism. Drug Metab Dispos 2005; 33: 139.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 139
-
-
Picard, N.1
Ratanasavanh, D.2
Premaud, A.3
-
4
-
-
0029864837
-
Pharmacokinetics and bioavailability of mycophenolate mofetil in healthy subjects after singledose oral and intravenous administration
-
Bullingham R, Monroe S, Nicholls A, et al. Pharmacokinetics and bioavailability of mycophenolate mofetil in healthy subjects after singledose oral and intravenous administration. J Clin Pharmacol 1996; 36: 315.
-
(1996)
J Clin Pharmacol
, vol.36
, pp. 315
-
-
Bullingham, R.1
Monroe, S.2
Nicholls, A.3
-
5
-
-
33645123973
-
Comparison of mycophenolic acid pharmacokinetic parameters in kidney transplant patients within the first 3 months post-transplant
-
Pawinski T, Durlik M, Szlaska I, et al. Comparison of mycophenolic acid pharmacokinetic parameters in kidney transplant patients within the first 3 months post-transplant. J Clin Pharm Ther 2006; 31: 27.
-
(2006)
J Clin Pharm Ther
, vol.31
, pp. 27
-
-
Pawinski, T.1
Durlik, M.2
Szlaska, I.3
-
6
-
-
0038298273
-
Long-term changes in mycophenolic acid exposure in combination with tacrolimus and corticosteroids are dose dependent and not reflected by trough plasma concentration: A prospective study in 100 de novo renal allograft recipients
-
Kuypers DR, Claes K, Evenepoel P, et al. Long-term changes in mycophenolic acid exposure in combination with tacrolimus and corticosteroids are dose dependent and not reflected by trough plasma concentration: A prospective study in 100 de novo renal allograft recipients. J Clin Pharmacol 2003; 43: 866.
-
(2003)
J Clin Pharmacol
, vol.43
, pp. 866
-
-
Kuypers, D.R.1
Claes, K.2
Evenepoel, P.3
-
7
-
-
77749325097
-
Consensus report on therapeutic drug monitoring of mycophenolic acid in solid organ transplantation
-
Kuypers DR, Le Meur Y, Cantarovich M, et al. Consensus report on therapeutic drug monitoring of mycophenolic acid in solid organ transplantation. Clin J Am Soc Nephrol 2010; 5: 341.
-
(2010)
Clin J Am Soc Nephrol
, vol.5
, pp. 341
-
-
Kuypers, D.R.1
Le Meur, Y.2
Cantarovich, M.3
-
8
-
-
13044305870
-
The pharmacokineticpharmacodynamic relationship for mycophenolate mofetil in renal transplantation
-
Hale MD, Nicholls AJ, Bullingham RE, et al. The pharmacokineticpharmacodynamic relationship for mycophenolate mofetil in renal transplantation. Clin Pharmacol Ther 1998; 64: 672.
-
(1998)
Clin Pharmacol Ther
, vol.64
, pp. 672
-
-
Hale, M.D.1
Nicholls, A.J.2
Bullingham, R.E.3
-
9
-
-
12944260647
-
Pharmacokinetic and metabolic investigations of mycophenolic acid in pediatric patients after renal transplantation: Implications for therapeutic drug monitoring.German study group on mycophenolate mofetil therapy in pediatric renal transplant recipients
-
Oellerich M, Shipkova M, Schutz E, et al. Pharmacokinetic and metabolic investigations of mycophenolic acid in pediatric patients after renal transplantation: Implications for therapeutic drug monitoring. German Study Group on Mycophenolate Mofetil Therapy in Pediatric Renal Transplant Recipients. Ther Drug Monit 2000; 22: 20.
-
(2000)
Ther Drug Monit
, vol.22
, pp. 20
-
-
Oellerich, M.1
Shipkova, M.2
Schutz, E.3
-
10
-
-
35248839494
-
Individualized mycophenolate mofetil dosing based on drug exposure significantly improves patient outcomes after renal transplantation
-
Le Meur Y, Buchler M, Thierry A, et al. Individualized mycophenolate mofetil dosing based on drug exposure significantly improves patient outcomes after renal transplantation. Am J Transplant 2007; 7: 2496.
-
(2007)
Am J Transplant
, vol.7
, pp. 2496
-
-
Le Meur, Y.1
Buchler, M.2
Thierry, A.3
-
11
-
-
0035086852
-
Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid
-
van Gelder T, Klupp J, Barten MJ, et al. Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid. Ther Drug Monit 2001; 23: 119.
-
(2001)
Ther Drug Monit
, vol.23
, pp. 119
-
-
Van Gelder, T.1
Klupp, J.2
Barten, M.J.3
-
12
-
-
33644824716
-
Influence of co-medication with sirolimus or cyclosporine on mycophenolic acid pharmacokinetics in kidney transplantation
-
Cattaneo D, Merlini S, Zenoni S, et al. Influence of co-medication with sirolimus or cyclosporine on mycophenolic acid pharmacokinetics in kidney transplantation. Am J Transplant 2005; 5: 2937.
-
(2005)
Am J Transplant
, vol.5
, pp. 2937
-
-
Cattaneo, D.1
Merlini, S.2
Zenoni, S.3
-
13
-
-
17644377916
-
Cyclosporine interacts with mycophenolic acid by inhibiting the multidrug resistance-associated protein
-
Hesselink DA, van Hest RM, Mathot RA, et al. Cyclosporine interacts with mycophenolic acid by inhibiting the multidrug resistance-associated protein Am J Transplant 2005; 5: 987.
-
(2005)
Am J Transplant
, vol.5
, pp. 987
-
-
Hesselink, D.A.1
Van Hest, R.M.2
Mathot, R.A.3
-
14
-
-
0031917826
-
Pharmacokinetics of mycophenolic acid in renal transplant patients with delayed graft function
-
Shaw LM, Mick R, Nowak I, et al. Pharmacokinetics of mycophenolic acid in renal transplant patients with delayed graft function. J Clin Pharmacol 1998; 38: 268.
-
(1998)
J Clin Pharmacol
, vol.38
, pp. 268
-
-
Shaw, L.M.1
Mick, R.2
Nowak, I.3
-
15
-
-
0033160692
-
The effect of renal insufficiency on mycophenolic acid protein binding
-
Kaplan B, Meier-Kriesche HU, Friedman G, et al. The effect of renal insufficiency on mycophenolic acid protein binding. J Clin Pharmacol 1999; 39: 715.
-
(1999)
J Clin Pharmacol
, vol.39
, pp. 715
-
-
Kaplan, B.1
Meier-Kriesche, H.U.2
Friedman, G.3
-
16
-
-
0031836455
-
The pharmacokinetics of a single oral dose of mycophenolate mofetil in patients with varying degrees of renal function
-
Johnson HJ, Swan SK, Heim-Duthoy KL, et al. The pharmacokinetics of a single oral dose of mycophenolate mofetil in patients with varying degrees of renal function. Clin Pharmacol Ther 1998; 63: 512.
-
(1998)
Clin Pharmacol Ther
, vol.63
, pp. 512
-
-
Johnson, H.J.1
Swan, S.K.2
Heim-Duthoy, K.L.3
-
17
-
-
33745491120
-
Pharmacokinetics of mycophenolic acid and metabolites in diabetic kidney transplant recipients
-
Akhlaghi F, Patel CG, Zuniga XP, et al. Pharmacokinetics of mycophenolic acid and metabolites in diabetic kidney transplant recipients. Ther Drug Monit 2006; 28: 95.
-
(2006)
Ther Drug Monit
, vol.28
, pp. 95
-
-
Akhlaghi, F.1
Patel, C.G.2
Zuniga, X.P.3
-
18
-
-
33645450634
-
Explaining variability in mycophenolic acid exposure to optimize mycophenolate mofetil dosing: A population pharmacokinetic meta-analysis of mycophenolic acid in renal transplant recipients
-
van Hest RM, Mathot RA, Pescovitz MD, et al. Explaining variability in mycophenolic acid exposure to optimize mycophenolate mofetil dosing: A population pharmacokinetic meta-analysis of mycophenolic acid in renal transplant recipients. J Am Soc Nephrol 2006; 17: 871.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 871
-
-
Van Hest, R.M.1
Mathot, R.A.2
Pescovitz, M.D.3
-
19
-
-
0033668361
-
Mycophenolic acid area under the curve values in African American and Caucasian renal transplant patients are comparable
-
Shaw LM, Korecka M, Aradhye S, et al. Mycophenolic acid area under the curve values in African American and Caucasian renal transplant patients are comparable. J Clin Pharmacol 2000; 40: 624.
-
(2000)
J Clin Pharmacol
, vol.40
, pp. 624
-
-
Shaw, L.M.1
Korecka, M.2
Aradhye, S.3
-
20
-
-
0036191888
-
The pharmacokineticpharmacodynamic relationship for total and free mycophenolic acid in pediatric renal transplant recipients: A report of the German study group on mycophenolate mofetil therapy
-
Weber LT, Shipkova M, Armstrong VW, et al. The pharmacokineticpharmacodynamic relationship for total and free mycophenolic acid in pediatric renal transplant recipients: A report of the German study group on mycophenolate mofetil therapy. J Am Soc Nephrol 2002; 13: 759.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 759
-
-
Weber, L.T.1
Shipkova, M.2
Armstrong, V.W.3
-
21
-
-
25144489979
-
Population pharmacokinetics of mycophenolic acid in renal transplant recipients
-
van Hest RM, van Gelder T, Vulto AG, et al. Population pharmacokinetics of mycophenolic acid in renal transplant recipients. Clin Pharmacokinet 2005; 44: 1083.
-
(2005)
Clin Pharmacokinet
, vol.44
, pp. 1083
-
-
Van Hest, R.M.1
Van Gelder, T.2
Vulto, A.G.3
-
22
-
-
34547876119
-
The impact of renal allograft function on exposure and elimination of mycophenolic acid (MPA) and its metabolite MPA 7-O-glucuronide
-
Naesens M, de Loor H, Vanrenterghem Y, et al. The impact of renal allograft function on exposure and elimination of mycophenolic acid (MPA) and its metabolite MPA 7-O-glucuronide. Transplantation 2007; 84: 362.
-
(2007)
Transplantation
, vol.84
, pp. 362
-
-
Naesens, M.1
De Loor, H.2
Vanrenterghem, Y.3
-
23
-
-
23244449306
-
Determinants of mycophenolic acid levels after renal transplantation
-
Borrows R, Chusney G, James A, et al. Determinants of mycophenolic acid levels after renal transplantation. Ther Drug Monit 2005; 27: 442.
-
(2005)
Ther Drug Monit
, vol.27
, pp. 442
-
-
Borrows, R.1
Chusney, G.2
James, A.3
-
24
-
-
0037373072
-
Pharmacokinetics of mycophenolate mofetil in patients with autoimmune diseases compared renal transplant recipients
-
Neumann I, Haidinger M, Jager H, et al. Pharmacokinetics of mycophenolate mofetil in patients with autoimmune diseases compared renal transplant recipients. J Am Soc Nephrol 2003; 14: 721.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 721
-
-
Neumann, I.1
Haidinger, M.2
Jager, H.3
-
25
-
-
0034815929
-
Effect of cyclosporine on mycophenolic acid area under the concentration-time curve in pediatric kidney transplant recipients
-
Filler G, Lepage N, Delisle B, et al. Effect of cyclosporine on mycophenolic acid area under the concentration-time curve in pediatric kidney transplant recipients. Ther Drug Monit 2001; 23: 514.
-
(2001)
Ther Drug Monit
, vol.23
, pp. 514
-
-
Filler, G.1
Lepage, N.2
Delisle, B.3
-
26
-
-
31444448077
-
Role of Mrp2 in the hepatic disposition of mycophenolic acid and its glucuronide metabolites: Effect of cyclosporine
-
Westley IS, Brogan LR, Morris RG, et al. Role of Mrp2 in the hepatic disposition of mycophenolic acid and its glucuronide metabolites: Effect of cyclosporine. Drug Metab Dispos 2006; 34: 261.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 261
-
-
Westley, I.S.1
Brogan, L.R.2
Morris, R.G.3
-
27
-
-
0032986770
-
Molecular aspects of organic compound transport across the plasma membrane of hepatocytes
-
Kamisako T, Gabazza EC, Ishihara T, et al. Molecular aspects of organic compound transport across the plasma membrane of hepatocytes. J Gastroenterol Hepatol 1999; 14: 405.
-
(1999)
J Gastroenterol Hepatol
, vol.14
, pp. 405
-
-
Kamisako, T.1
Gabazza, E.C.2
Ishihara, T.3
-
28
-
-
37549030838
-
Glucuronidation of mycophenolic acid by Wistar and Mrp2-deficient TR-rat liver microsomes
-
Westley IS, Morris RG, Evans AM, et al. Glucuronidation of mycophenolic acid by Wistar and Mrp2-deficient TR-rat liver microsomes. Drug Metab Dispos 2008; 36: 46.
-
(2008)
Drug Metab Dispos
, vol.36
, pp. 46
-
-
Westley, I.S.1
Morris, R.G.2
Evans, A.M.3
-
29
-
-
0033023263
-
Evidence that tacrolimus augments the bioavailability of mycophenolate mofetil through the inhibition of mycophenolic acid glucuronidation
-
Zucker K, Tsaroucha A, Olson L, et al. Evidence that tacrolimus augments the bioavailability of mycophenolate mofetil through the inhibition of mycophenolic acid glucuronidation. Ther Drug Monit 1999; 21: 35.
-
(1999)
Ther Drug Monit
, vol.21
, pp. 35
-
-
Zucker, K.1
Tsaroucha, A.2
Olson, L.3
-
30
-
-
65249122376
-
Influence of renal graft function on mycophenolic acid pharmacokinetics during the early period after kidney transplant
-
Mohammadpur AH, Nazemian F, Abtahi B, et al. Influence of renal graft function on mycophenolic acid pharmacokinetics during the early period after kidney transplant. Exp Clin Transplant 2008; 6: 276.
-
(2008)
Exp Clin Transplant
, vol.6
, pp. 276
-
-
Mohammadpur, A.H.1
Nazemian, F.2
Abtahi, B.3
-
31
-
-
32044439130
-
Effects of calcineurin inhibitors on pharmacokinetics of mycophenolic acid and its glucuronide metabolite during the maintenance period following renal transplantation
-
Naito T, Shinno K, Maeda T, et al. Effects of calcineurin inhibitors on pharmacokinetics of mycophenolic acid and its glucuronide metabolite during the maintenance period following renal transplantation. Biol Pharm Bull 2006; 29: 275.
-
(2006)
Biol Pharm Bull
, vol.29
, pp. 275
-
-
Naito, T.1
Shinno, K.2
Maeda, T.3
-
32
-
-
0033032730
-
Expression of the MRP2 geneencoded conjugate export pump in human kidney proximal tubules and in renal cell carcinoma
-
Schaub TP, Kartenbeck J, Konig J, et al. Expression of the MRP2 geneencoded conjugate export pump in human kidney proximal tubules and in renal cell carcinoma. J Am Soc Nephrol 1999; 10: 1159.
-
(1999)
J Am Soc Nephrol
, vol.10
, pp. 1159
-
-
Schaub, T.P.1
Kartenbeck, J.2
Konig, J.3
-
33
-
-
67650215373
-
Mycophenolic acid exposure after administration of mycophenolate mofetil in the presence and absence of cyclosporin in renal transplant recipients
-
Kuypers DR, Ekberg H, Grinyo J, et al. Mycophenolic acid exposure after administration of mycophenolate mofetil in the presence and absence of cyclosporin in renal transplant recipients. Clin Pharmacokinet 2009; 48: 329.
-
(2009)
Clin Pharmacokinet
, vol.48
, pp. 329
-
-
Kuypers, D.R.1
Ekberg, H.2
Grinyo, J.3
-
34
-
-
0036205460
-
Gene expression levels and immunolocalization of organic ion transporters in the human kidney
-
Motohashi H, Sakurai Y, Saito H, et al. Gene expression levels and immunolocalization of organic ion transporters in the human kidney. J Am Soc Nephrol 2002; 13: 866.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 866
-
-
Motohashi, H.1
Sakurai, Y.2
Saito, H.3
-
35
-
-
34249014286
-
Interaction and transport characteristics of mycophenolic acid and its glucuronide via human organic anion transporters hOAT1 and hOAT3
-
Uwai Y, Motohashi H, Tsuji Y, et al. Interaction and transport characteristics of mycophenolic acid and its glucuronide via human organic anion transporters hOAT1 and hOAT3. Biochem Pharmacol 2007; 74: 161.
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 161
-
-
Uwai, Y.1
Motohashi, H.2
Tsuji, Y.3
-
36
-
-
33746364150
-
Effects of indoxylsulfate on the in vitro hepatic metabolism of various compounds using human liver microsomes and hepatocytes
-
Hanada K, Ogawa R, Son K, et al. Effects of indoxylsulfate on the in vitro hepatic metabolism of various compounds using human liver microsomes and hepatocytes. Nephron Physiol 2006; 103: 179.
-
(2006)
Nephron Physiol
, vol.103
, pp. 179
-
-
Hanada, K.1
Ogawa, R.2
Son, K.3
-
37
-
-
68949205021
-
Pharmacokinetic modelling of the plasma protein binding of mycophenolic acid in renal transplant recipients
-
van Hest RM, van Gelder T, Vulto AG, et al. Pharmacokinetic modelling of the plasma protein binding of mycophenolic acid in renal transplant recipients. Clin Pharmacokinet 2009; 48: 463.
-
(2009)
Clin Pharmacokinet
, vol.48
, pp. 463
-
-
Van Hest, R.M.1
Van Gelder, T.2
Vulto, A.G.3
-
38
-
-
2542590879
-
Free mycophenolic acid should be monitored in renal transplant recipients with hypoalbuminemia
-
Atcheson BA, Taylor PJ, Kirkpatrick CM, et al. Free mycophenolic acid should be monitored in renal transplant recipients with hypoalbuminemia. Ther Drug Monit 2004; 26: 284.
-
(2004)
Ther Drug Monit
, vol.26
, pp. 284
-
-
Atcheson, B.A.1
Taylor, P.J.2
Kirkpatrick, C.M.3
-
39
-
-
0033281413
-
Effect of mycophenolate mofetil on erythropoiesis in stable renal transplant patients is correlated with mycophenolic acid trough levels
-
van Besouw NM, van der Mast BJ, Smak Gregoor PJ, et al. Effect of mycophenolate mofetil on erythropoiesis in stable renal transplant patients is correlated with mycophenolic acid trough levels. Nephrol Dial Transplant 1999; 14: 2710.
-
(1999)
Nephrol Dial Transplant
, vol.14
, pp. 2710
-
-
Van Besouw, N.M.1
Van Der Mast, B.J.2
Smak Gregoor, P.J.3
-
40
-
-
44449123532
-
Anaemia and congestive heart failure early post-renal transplantation
-
Borrows R, Loucaidou M, Chusney G, et al. Anaemia and congestive heart failure early post-renal transplantation. Nephrol Dial Transplant 2008; 23: 1728.
-
(2008)
Nephrol Dial Transplant
, vol.23
, pp. 1728
-
-
Borrows, R.1
Loucaidou, M.2
Chusney, G.3
-
41
-
-
0029885182
-
Effects of food and antacid on the pharmacokinetics of single doses of mycophenolate mofetil in rheumatoid arthritis patients
-
Bullingham R, Shah J, Goldblum R, et al. Effects of food and antacid on the pharmacokinetics of single doses of mycophenolate mofetil in rheumatoid arthritis patients. Br J Clin Pharmacol 1996; 41: 513.
-
(1996)
Br J Clin Pharmacol
, vol.41
, pp. 513
-
-
Bullingham, R.1
Shah, J.2
Goldblum, R.3
-
42
-
-
38549136645
-
Influence of lansoprazole and rabeprazole on mycophenolic acid pharmacokinetics one year after renal transplantation
-
Miura M, Satoh S, Inoue K, et al. Influence of lansoprazole and rabeprazole on mycophenolic acid pharmacokinetics one year after renal transplantation. Ther Drug Monit 2008; 30: 46.
-
(2008)
Ther Drug Monit
, vol.30
, pp. 46
-
-
Miura, M.1
Satoh, S.2
Inoue, K.3
-
43
-
-
33746833139
-
Basiliximab combined with low-dose rabbit anti-human thymocyte globulin: A possible further step toward effective and minimally toxic T cell-targeted therapy in kidney transplantation
-
Ruggenenti P, Codreanu I, Cravedi P, et al. Basiliximab combined with low-dose rabbit anti-human thymocyte globulin: A possible further step toward effective and minimally toxic T cell-targeted therapy in kidney transplantation. Clin J Am Soc Nephrol 2006; 1: 546.
-
(2006)
Clin J Am Soc Nephrol
, vol.1
, pp. 546
-
-
Ruggenenti, P.1
Codreanu, I.2
Cravedi, P.3
-
44
-
-
31044444888
-
Simultaneous determination of everolimus and cyclosporine concentrations by HPLC with ultraviolet detection
-
Baldelli S, Zenoni S, Merlini S, et al. Simultaneous determination of everolimus and cyclosporine concentrations by HPLC with ultraviolet detection. Clin Chim Acta 2006; 364: 354.
-
(2006)
Clin Chim Acta
, vol.364
, pp. 354
-
-
Baldelli, S.1
Zenoni, S.2
Merlini, S.3
-
45
-
-
35348836649
-
C-440T/T-331C polymorphisms in the UGT1A9 gene affect the pharmacokinetics of mycophenolic acid in kidney transplantation
-
Baldelli S, Merlini S, Perico N, et al. C-440T/T-331C polymorphisms in the UGT1A9 gene affect the pharmacokinetics of mycophenolic acid in kidney transplantation. Pharmacogenomics 2007; 8: 1127.
-
(2007)
Pharmacogenomics
, vol.8
, pp. 1127
-
-
Baldelli, S.1
Merlini, S.2
Perico, N.3
|