Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα

Redox Biology

Volumn 6, Issue , 2015, Pages 640-647

  Carrim, Naadiya ^a   Arthur, Jane F ^b   Hamilton, Justin R ^b   Gardiner, Elizabeth E ^b   Andrews, Robert K ^b   Moran, Niamh ^a   Berndt, Michael C ^a,c   Metharom, Pat ^a,c,d  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b MONASH UNIVERSITY   (Australia)

^c CURTIN UNIVERSITY   (Australia)

^d CURTIN UNIVERSITY   (Australia)

Author keywords

PAR1 and PAR4; Platelets; Reactive oxygen species; Receptors GPIb ; Thrombin

Indexed keywords

1 AMINO 3 CYCLOPROPYLAMINO 7 (4 ISOPROPYLBENZYL) 7H PYRROLO[3,2 F]QUINAZOLINE; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; BMS 200261; FOCAL ADHESION KINASE; GLYCOSYLPHOSPHATIDYLINOSITOL; GLYCOSYLPHOSPHATIDYLINOSITOL B ALPHA; PF 228; PROTEINASE; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 1 ANTAGONIST; PROTEINASE ACTIVATED RECEPTOR 4; PROTEINASE ACTIVATED RECEPTOR 4 ANTAGONIST; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; THROMBIN; UNCLASSIFIED DRUG; ADHESION RECEPTOR; FOCAL ADHESION KINASE 1; NOX1 PROTEIN, HUMAN; PROTEASE-ACTIVATED RECEPTOR 4; PTK2 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; THROMBIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LIGAND BINDING; MOUSE; NAJA; NAJA KAOUTHIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEFICIENCY; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; PROTEINASE ACTIVATED RECEPTOR 4 DEFICIENCY; QUANTITATIVE ANALYSIS; RAT; THROMBOCYTE ACTIVATION; ANIMAL; CHLOROCEBUS AETHIOPS; COS CELL LINE; ENZYMOLOGY; METABOLISM; PHYSIOLOGY; THROMBOCYTE;

ANIMALS; BLOOD PLATELETS; CERCOPITHECUS AETHIOPS; COS CELLS; FOCAL ADHESION KINASE 1; HUMANS; MICE; NADPH OXIDASE; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; REACTIVE OXYGEN SPECIES; RECEPTOR, PAR-1; RECEPTORS, THROMBIN; THROMBIN;

EID: 84946750364     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2015.10.009     Document Type: Article

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