Dissociation of locomotor and cerebellar deficits in a murine Angelman syndrome model

Journal of Clinical Investigation

Volumn 125, Issue 11, 2015, Pages 4305-4315

  Bruinsma, Caroline F ^a   Schonewille, Martijn ^a   Gao, Zhenyu ^a   Aronica, Eleonora M A ^b   Judson, Matthew C ^c   Philpot, Benjamin D ^c   Hoebeek, Freek E ^a   Van Woerden, Geeske M ^a   De Zeeuw, Chris I ^a,d   Elgersma, Ype ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CEREBELLAR SPECIFIC VESTIBULOOCULAR REFLEX; CEREBELLUM CORTEX; CEREBELLUM GRANULAR LAYER; CONTROLLED STUDY; DOUBLE DISSOCIATION; FEMALE; GENE; GENETIC MANIPULATION; GRANULE CELL; HAPPY PUPPET SYNDROME; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LEARNING DISORDER; LOCOMOTION; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MOTOR COORDINATION; MOTOR DYSFUNCTION; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; OCULOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PURKINJE CELL; SIGNAL TRANSDUCTION; UBE3A GENE; VESTIBULOOCULAR REFLEX; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CEREBELLUM; DEFICIENCY; DISEASE MODEL; GENETICS; MALE; NEUROLOGIC GAIT DISORDER; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; PSYCHOMOTOR PERFORMANCE; ROTAROD TEST;

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; UBE3A PROTEIN, MOUSE; UBIQUITIN PROTEIN LIGASE;

ANGELMAN SYNDROME; ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CEREBELLUM; DISEASE MODELS, ANIMAL; FEMALE; GAIT DISORDERS, NEUROLOGIC; HUMANS; LEARNING DISORDERS; LOCOMOTION; MALE; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PSYCHOMOTOR PERFORMANCE; PURKINJE CELLS; REFLEX, VESTIBULO-OCULAR; ROTAROD PERFORMANCE TEST; UBIQUITIN-PROTEIN LIGASES;

EID: 84946714434     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI83541     Document Type: Article

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