Raising cytosolic Cl - in cerebellar granule cells affects their excitability and vestibulo-ocular learning

EMBO Journal

Volumn 31, Issue 5, 2012, Pages 1217-1230

  Seja, Patricia ^a   Schonewille, Martijn ^b   Spitzmaul, Guillermo ^a   Badura, Aleksandra ^b   Klein, Ilse ^c   Rudhard, York ^c   Wisden, William ^d   Hübner, Christian A ^c,e   De Zeeuw, Chris I ^b,f   Jentsch, Thomas J ^a,c,g  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF HAMBURG   (Germany)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e JENA UNIVERSITY HOSPITAL   (Germany)

^f NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^g CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

dendritic spine; GABA switch; glycine receptor; potassium chloride cotransporter; synaptic inhibition

Indexed keywords

BETA ACTIN; CHLORIDE; CHLORIDE CHANNEL; GABAERGIC RECEPTOR AFFECTING AGENT; POTASSIUM CHLORIDE COTRANSPORTER; PROTEIN KCC2; PROTEIN KCC3; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL TYPE; CEREBELLUM; CONTROLLED STUDY; CYTOSOL; GABAERGIC SYSTEM; GENE; GENE DISRUPTION; GRANULE CELL; HYPERPOLARIZATION; INTERNEURON; KCC2 GENE; LEARNING; MEMBRANE DEPOLARIZATION; MOTOR CONTROL; MOUSE; NERVE CELL EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; SYNAPSE; VESTIBULOOCULAR REFLEX;

ANIMALS; CEREBELLAR CORTEX; CHLORIDES; CYTOSOL; LEARNING; MICE; MICE, KNOCKOUT; NEURONS; REFLEX, VESTIBULO-OCULAR; SYMPORTERS;

EID: 84857999226     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.488     Document Type: Article

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