메뉴 건너뛰기




Volumn 70, Issue 11, 2015, Pages 1360-1369

Sexual Dimorphism in the Alterations of Cardiac Muscle Mitochondrial Bioenergetics Associated to the Ageing Process

Author keywords

Aging; Energy metabolism; Heart; Mitochondria; Sex

Indexed keywords

ADENOSINE TRIPHOSPHATASE; DNA BINDING PROTEIN; HYDROGEN PEROXIDE; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL TRANSCRIPTION FACTOR A; MULTIENZYME COMPLEX; TRANSCRIPTION FACTOR;

EID: 84946570985     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glu014     Document Type: Article
Times cited : (15)

References (52)
  • 2
    • 34447517169 scopus 로고    scopus 로고
    • Gender-based differences in mechanisms of protection in myocardial ischemia-reperfusion injury
    • Murphy E, Steenbergen C. Gender-based differences in mechanisms of protection in myocardial ischemia-reperfusion injury. Cardiovasc Res. 2007;75:478-486. doi:10.1016/j.cardiores.2007.03.025
    • (2007) Cardiovasc Res. , vol.75 , pp. 478-486
    • Murphy, E.1    Steenbergen, C.2
  • 4
    • 0033537674 scopus 로고    scopus 로고
    • Sex, age, cardiovascular risk factors, and coronary heart disease: A prospective follow-up study of 14 786 middle-aged men and women in Finland
    • Jousilahti P, Vartiainen E, Tuomilehto J, Puska P. Sex, age, cardiovascular risk factors, and coronary heart disease: a prospective follow-up study of 14 786 middle-aged men and women in Finland. Circulation. 1999;99:1165-1172. doi:10.1161/01.CIR.99.9.1165
    • (1999) Circulation , vol.99 , pp. 1165-1172
    • Jousilahti, P.1    Vartiainen, E.2    Tuomilehto, J.3    Puska, P.4
  • 5
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
    • Rossouw JE, Anderson GL, Prentice RL, et al.; Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA. 2002;288:321-333. doi:10.1001/jama.288.3.321
    • (2002) JAMA , vol.288 , pp. 321-333
    • Rossouw, J.E.1    Anderson, G.L.2    Prentice, R.L.3
  • 7
    • 0033796250 scopus 로고    scopus 로고
    • Mitochondrial free radical generation, oxidative stress, and aging
    • Cadenas E, Davies KJ. Mitochondrial free radical generation, oxidative stress, and aging. Free Radic Biol Med. 2000;29:222-230. doi:10.1016/S0891-5849(00)00317-8
    • (2000) Free Radic Biol Med. , vol.29 , pp. 222-230
    • Cadenas, E.1    Davies, K.J.2
  • 8
    • 0030793931 scopus 로고    scopus 로고
    • Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon
    • Herrero A, Barja G. Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon. Mech Ageing Dev. 1997;98:95-111. doi:10.1016/S0047-6374(97) 00076-6
    • (1997) Mech Ageing Dev. , vol.98 , pp. 95-111
    • Herrero, A.1    Barja, G.2
  • 9
    • 0034749276 scopus 로고    scopus 로고
    • Mitochondrial pathology in cardiac failure
    • Marin-Garcia J, Goldenthal MJ, Moe GW. Mitochondrial pathology in cardiac failure. Cardiovasc Res. 2001;49:17-26. doi:10.1016/S0008-6363(00)00241-8
    • (2001) Cardiovasc Res. , vol.49 , pp. 17-26
    • Marin-Garcia, J.1    Goldenthal, M.J.2    Moe, G.W.3
  • 10
    • 0142025366 scopus 로고    scopus 로고
    • Review: Mitochondrial medicine-cardiomyopathy caused by defective oxidative phosphorylation
    • Fosslien E. Review: mitochondrial medicine-cardiomyopathy caused by defective oxidative phosphorylation. Ann Clin Lab Sci. 2003;33:371-395.
    • (2003) Ann Clin Lab Sci. , vol.33 , pp. 371-395
    • Fosslien, E.1
  • 11
    • 41249086364 scopus 로고    scopus 로고
    • Mitochondrial centrality in heart failure
    • Marín-García J, Goldenthal MJ. Mitochondrial centrality in heart failure. Heart Fail Rev. 2008;13:137-150. doi:10.1007/s10741-007-9079-1
    • (2008) Heart Fail Rev. , vol.13 , pp. 137-150
    • Marín-García, J.1    Goldenthal, M.J.2
  • 12
    • 3543028676 scopus 로고    scopus 로고
    • Understanding aging: Revealing order out of chaos
    • Dufour E, Larsson NG. Understanding aging: revealing order out of chaos. Biochim Biophys Acta. 2004;1658:122-132. doi:10.1016/j.bbabio. 2004.04.020
    • (2004) Biochim Biophys Acta. , vol.1658 , pp. 122-132
    • Dufour, E.1    Larsson, N.G.2
  • 13
    • 84859897199 scopus 로고    scopus 로고
    • Mitochondria and aging
    • Lee HC, Wei YH. Mitochondria and aging. Adv Exp Med Biol. 2012;942:311-327. doi:10.1007/978-94-007-2869-1-14.
    • (2012) Adv Exp Med Biol. , vol.942 , pp. 311-327
    • Lee, H.C.1    Wei, Y.H.2
  • 14
    • 0034960785 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in cardiac disease: Ischemia-reperfusion, aging, and heart failure
    • Lesnefsky EJ, Moghaddas S, Tandler B, Kerner J, Hoppel CL. Mitochondrial dysfunction in cardiac disease: ischemia-reperfusion, aging, and heart failure. J Mol Cell Cardiol. 2001;33:1065-1089. doi:10.1006/jmcc.2001.1378
    • (2001) J Mol Cell Cardiol. , vol.33 , pp. 1065-1089
    • Lesnefsky, E.J.1    Moghaddas, S.2    Tandler, B.3    Kerner, J.4    Hoppel, C.L.5
  • 15
    • 77958032255 scopus 로고    scopus 로고
    • Decrease in mitochondrial function in rat cardiac permeabilized fibers correlates with the aging phenotype
    • Lemieux H, Vazquez EJ, Fujioka H, Hoppel CL. Decrease in mitochondrial function in rat cardiac permeabilized fibers correlates with the aging phenotype. J Gerontol A Biol Sci Med Sci. 2010;65:1157-1164. doi:10.1093/gerona/glq141
    • (2010) J Gerontol A Biol Sci Med Sci. , vol.65 , pp. 1157-1164
    • Lemieux, H.1    Vazquez, E.J.2    Fujioka, H.3    Hoppel, C.L.4
  • 16
    • 64949111531 scopus 로고    scopus 로고
    • Current thoughts on the role of mitochondria and free radicals in the biology of aging
    • Van Remmen H, Jones DP. Current thoughts on the role of mitochondria and free radicals in the biology of aging. J Gerontol A Biol Sci Med Sci. 2009;64:171-174. doi:10.1093/gerona/gln058
    • (2009) J Gerontol A Biol Sci Med Sci. , vol.64 , pp. 171-174
    • Van Remmen, H.1    Jones, D.P.2
  • 17
    • 34247873129 scopus 로고    scopus 로고
    • Caloric restriction and gender modulate cardiac muscle mitochondrial H2O2 production and oxidative damage
    • Colom B, Oliver J, Roca P, Garcia-Palmer FJ. Caloric restriction and gender modulate cardiac muscle mitochondrial H2O2 production and oxidative damage. Cardiovasc Res. 2007;74:456-465. doi:10.1016/j.cardiores. 2007.02.001
    • (2007) Cardiovasc Res. , vol.74 , pp. 456-465
    • Colom, B.1    Oliver, J.2    Roca, P.3    Garcia-Palmer, F.J.4
  • 18
    • 33847022351 scopus 로고    scopus 로고
    • Skeletal muscle of female rats exhibit higher mitochondrial mass and oxidative-phosphorylative capacities compared to males
    • Colom B, Alcolea MP, Valle A, Oliver J, Roca P, García-Palmer FJ. Skeletal muscle of female rats exhibit higher mitochondrial mass and oxidative-phosphorylative capacities compared to males. Cell Physiol Biochem. 2007;19:205-212. doi:10.1159/000099208
    • (2007) Cell Physiol Biochem. , vol.19 , pp. 205-212
    • Colom, B.1    Alcolea, M.P.2    Valle, A.3    Oliver, J.4    Roca, P.5    García-Palmer, F.J.6
  • 20
    • 0037044744 scopus 로고    scopus 로고
    • Sex-dependent thermogenesis, differences in mitochondrial morphology and function, and adrenergic response in brown adipose tissue
    • Rodriguez-Cuenca S, Pujol E, Justo R, et al. Sex-dependent thermogenesis, differences in mitochondrial morphology and function, and adrenergic response in brown adipose tissue. J Biol Chem. 2002;277:42958-42963. doi:10.1074/jbc.M207229200
    • (2002) J Biol Chem. , vol.277 , pp. 42958-42963
    • Rodriguez-Cuenca, S.1    Pujol, E.2    Justo, R.3
  • 21
    • 33845991136 scopus 로고    scopus 로고
    • Expression of mitochondrial biogenesis-signaling factors in brown adipocytes is influenced specifically by 17beta-estradiol, testosterone, and progesterone
    • Rodríguez-Cuenca S, Monjo M, Gianotti M, Proenza AM, Roca P. Expression of mitochondrial biogenesis-signaling factors in brown adipocytes is influenced specifically by 17beta-estradiol, testosterone, and progesterone. Am J Physiol Endocrinol Metab. 2007;292:E340-E346. doi:10.1152/ajpendo.00175.2006
    • (2007) Am J Physiol Endocrinol Metab. , vol.292 , pp. E340-E346
    • Rodríguez-Cuenca, S.1    Monjo, M.2    Gianotti, M.3    Proenza, A.M.4    Roca, P.5
  • 22
    • 0018164593 scopus 로고
    • Specific measurement of DNA in nuclei and nucleic acids using diaminobenzoic acid
    • Thomas PS, Farquhar MN. Specific measurement of DNA in nuclei and nucleic acids using diaminobenzoic acid. Anal Biochem. 1978;89:35-44. doi:10.1016/0003-2697(78)90724-8
    • (1978) Anal Biochem. , vol.89 , pp. 35-44
    • Thomas, P.S.1    Farquhar, M.N.2
  • 23
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-254. doi:10.1016/0003-2697(76)90527-3
    • (1976) Anal Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 24
    • 0033695152 scopus 로고    scopus 로고
    • Gender-differences in myocardial adaptation to afterload in normotensive and hypertensive rats
    • Wallen WJ, Cserti C, Belanger MP, Wittnich C. Gender-differences in myocardial adaptation to afterload in normotensive and hypertensive rats. Hypertension. 2000;36:774-779. doi:10.1161/01.HYP.36.5.774
    • (2000) Hypertension , vol.36 , pp. 774-779
    • Wallen, W.J.1    Cserti, C.2    Belanger, M.P.3    Wittnich, C.4
  • 25
    • 0025801813 scopus 로고
    • Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy
    • Olivetti G, Melissari M, Capasso JM, Anversa P. Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy. Circ Res. 1991;68:1560-1568. doi:10.1161/01.RES.68.6.1560
    • (1991) Circ Res. , vol.68 , pp. 1560-1568
    • Olivetti, G.1    Melissari, M.2    Capasso, J.M.3    Anversa, P.4
  • 26
    • 0019083215 scopus 로고
    • Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria
    • Turrens JF, Boveris A. Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria. Biochem J. 1980;191:421-427.
    • (1980) Biochem J. , vol.191 , pp. 421-427
    • Turrens, J.F.1    Boveris, A.2
  • 27
    • 0021996572 scopus 로고
    • Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria
    • Turrens JF, Alexandre A, Lehninger AL. Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria. Arch Biochem Biophys. 1985;237:408-414. doi:10.1016/0003-9861(85)90293-0
    • (1985) Arch Biochem Biophys. , vol.237 , pp. 408-414
    • Turrens, J.F.1    Alexandre, A.2    Lehninger, A.L.3
  • 28
    • 5444228319 scopus 로고    scopus 로고
    • Regulation of mitochondrial proliferation in the heart: Power-plant failure contributes to cardiac failure in hypertrophy
    • Goffart S, von Kleist-Retzow JC, Wiesner RJ. Regulation of mitochondrial proliferation in the heart: power-plant failure contributes to cardiac failure in hypertrophy. Cardiovasc Res. 2004;64:198-207. doi:10.1016/j. cardiores.2004.06.030
    • (2004) Cardiovasc Res. , vol.64 , pp. 198-207
    • Goffart, S.1    Von Kleist-Retzow, J.C.2    Wiesner, R.J.3
  • 29
    • 0034602958 scopus 로고    scopus 로고
    • Effects of aging on mitochondrial DNA copy number and cytochrome c oxidase gene expression in rat skeletal muscle, liver, and heart
    • Barazzoni R, Short KR, Nair KS. Effects of aging on mitochondrial DNA copy number and cytochrome c oxidase gene expression in rat skeletal muscle, liver, and heart. J Biol Chem. 2000;275:3343-3347. doi:10.1074/jbc.275.5.3343
    • (2000) J Biol Chem. , vol.275 , pp. 3343-3347
    • Barazzoni, R.1    Short, K.R.2    Nair, K.S.3
  • 30
    • 0037474446 scopus 로고    scopus 로고
    • Acetylation and level of mitochondrial transcription factor A in several organs of young and old rats
    • Dinardo MM, Musicco C, Fracasso F, et al. Acetylation and level of mitochondrial transcription factor A in several organs of young and old rats. Biochem Biophys Res Commun. 2003;301:187-191. doi:10.1016/S0006-291X(02)03008-5
    • (2003) Biochem Biophys Res Commun. , vol.301 , pp. 187-191
    • Dinardo, M.M.1    Musicco, C.2    Fracasso, F.3
  • 31
    • 3042558060 scopus 로고    scopus 로고
    • Age-associated decreased activities of mitochondrial electron transport chain complexes in heart and skeletal muscle: Role of L-carnitine
    • Kumaran S, Subathra M, Balu M, Panneerselvam C. Age-associated decreased activities of mitochondrial electron transport chain complexes in heart and skeletal muscle: role of L-carnitine. Chem Biol Interact. 2004;148:11-18. doi:10.1016/j.cbi.2003.10.010
    • (2004) Chem Biol Interact. , vol.148 , pp. 11-18
    • Kumaran, S.1    Subathra, M.2    Balu, M.3    Panneerselvam, C.4
  • 32
    • 0033958726 scopus 로고    scopus 로고
    • Age-related changes in activities of mitochondrial electron transport complexes in various tissues of the mouse
    • Kwong LK, Sohal RS. Age-related changes in activities of mitochondrial electron transport complexes in various tissues of the mouse. Arch Biochem Biophys. 2000;373:16-22. doi:10.1006/abbi.1999.1495
    • (2000) Arch Biochem Biophys. , vol.373 , pp. 16-22
    • Kwong, L.K.1    Sohal, R.S.2
  • 34
    • 75649142161 scopus 로고    scopus 로고
    • The effect of aging on human skeletal muscle mitochondrial and intramyocellular lipid ultrastructure
    • Crane JD, Devries MC, Safdar A, Hamadeh MJ, Tarnopolsky MA. The effect of aging on human skeletal muscle mitochondrial and intramyocellular lipid ultrastructure. J Gerontol A Biol Sci Med Sci. 2010;65:119-128. doi:10.1093/gerona/glp179.
    • (2010) J Gerontol A Biol Sci Med Sci. , vol.65 , pp. 119-128
    • Crane, J.D.1    Devries, M.C.2    Safdar, A.3    Hamadeh, M.J.4    Tarnopolsky, M.A.5
  • 35
    • 84862013849 scopus 로고    scopus 로고
    • Age and ovariectomy abolish beneficial effects of female sex on rat ventricular myocytes exposed to simulated ischemia and reperfusion
    • Ross JL, Howlett SE. Age and ovariectomy abolish beneficial effects of female sex on rat ventricular myocytes exposed to simulated ischemia and reperfusion. PLoS One. 2012;7:e38425. doi:10.1371/journal. pone.0038425
    • (2012) PLoS One , vol.7 , pp. e38425
    • Ross, J.L.1    Howlett, S.E.2
  • 36
    • 84864459562 scopus 로고    scopus 로고
    • Sexual hormones: Effects on cardiac and mitochondrial activity after ischemia-reperfusion in adult rats. Gender difference
    • Pavón N, Martínez-Abundis E, Hernández L, et al. Sexual hormones: effects on cardiac and mitochondrial activity after ischemia-reperfusion in adult rats. Gender difference. J Steroid Biochem Mol Biol. 2012;132:135-146. doi:10.1016/j.jsbmb.2012.05.003
    • (2012) J Steroid Biochem Mol Biol. , vol.132 , pp. 135-146
    • Pavón, N.1    Martínez-Abundis, E.2    Hernández, L.3
  • 37
    • 0024146932 scopus 로고
    • Biogenesis of mitochondria
    • Attardi G, Schatz G. Biogenesis of mitochondria. Annu Rev Cell Biol. 1988;4:289-333. doi: 10.1146/annurev.cb.04.110188.001445
    • (1988) Annu Rev Cell Biol. , vol.4 , pp. 289-333
    • Attardi, G.1    Schatz, G.2
  • 38
    • 0030809575 scopus 로고    scopus 로고
    • Regulation of mitochondrial transcription by mitochondrial transcription factor A
    • Montoya J, Perez-Martos A, Garstka HL, Wiesner RJ. Regulation of mitochondrial transcription by mitochondrial transcription factor A. Mol Cell Biochem. 1997;174:227-230. doi:10.1007/978-1-4615-6111-8-35
    • (1997) Mol Cell Biochem. , vol.174 , pp. 227-230
    • Montoya, J.1    Perez-Martos, A.2    Garstka, H.L.3    Wiesner, R.J.4
  • 40
    • 34547839596 scopus 로고    scopus 로고
    • Mitochondrial differentiation and oxidative phosphorylation system capacity in rat embryo during placentation period
    • Alcolea MP, Colom B, Lladó I, García-Palmer FJ, Gianotti M. Mitochondrial differentiation and oxidative phosphorylation system capacity in rat embryo during placentation period. Reproduction. 2007;134:147-154. doi:10.1530/REP-07-0012
    • (2007) Reproduction , vol.134 , pp. 147-154
    • Alcolea, M.P.1    Colom, B.2    Lladó, I.3    García-Palmer, F.J.4    Gianotti, M.5
  • 41
    • 33645009616 scopus 로고    scopus 로고
    • Mitochondrial transcription factor A (TFAM) is increased in rat embryo during placentation and associated with mitochondrial differentiation
    • Alcolea MP, Colom B, Lladó I, Gianotti M, García-Palmer FJ. Mitochondrial transcription factor A (TFAM) is increased in rat embryo during placentation and associated with mitochondrial differentiation. Cell Physiol Biochem. 2006;17:79-88. doi:10.1159/000091466
    • (2006) Cell Physiol Biochem. , vol.17 , pp. 79-88
    • Alcolea, M.P.1    Colom, B.2    Lladó, I.3    Gianotti, M.4    García-Palmer, F.J.5
  • 42
    • 0034724327 scopus 로고    scopus 로고
    • Genetic modification of survival in tissue-specific knockout mice with mitochondrial cardiomyopathy
    • Li H, Wang J, Wilhelmsson H, et al. Genetic modification of survival in tissue-specific knockout mice with mitochondrial cardiomyopathy. Proc Natl Acad Sci USA. 2000;97:3467-3472. doi:10.1073/pnas.97.7.3467
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3467-3472
    • Li, H.1    Wang, J.2    Wilhelmsson, H.3
  • 43
    • 23244452012 scopus 로고    scopus 로고
    • Overexpression of mitochondrial transcription factor a ameliorates mitochondrial deficiencies and cardiac failure after myocardial infarction
    • Ikeuchi M, Matsusaka H, Kang D, et al. Overexpression of mitochondrial transcription factor a ameliorates mitochondrial deficiencies and cardiac failure after myocardial infarction. Circulation. 2005;112:683-690. doi:10.1161/CIRCULATIONAHA.104.524835
    • (2005) Circulation , vol.112 , pp. 683-690
    • Ikeuchi, M.1    Matsusaka, H.2    Kang, D.3
  • 44
    • 0032924872 scopus 로고    scopus 로고
    • Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression
    • Wang J, Wilhelmsson H, Graff C, et al. Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression. Nat Genet. 1999;21:133-137. doi:10.1038/5089
    • (1999) Nat Genet. , vol.21 , pp. 133-137
    • Wang, J.1    Wilhelmsson, H.2    Graff, C.3
  • 45
    • 0038367809 scopus 로고    scopus 로고
    • Aging defect at the QO site of complex III augments oxyradical production in rat heart interfibrillar mitochondria
    • Moghaddas S, Hoppel CL, Lesnefsky EJ. Aging defect at the QO site of complex III augments oxyradical production in rat heart interfibrillar mitochondria. Arch Biochem Biophys. 2003;414:59-66. doi:10.1016/S0003-9861(03)00166-8
    • (2003) Arch Biochem Biophys. , vol.414 , pp. 59-66
    • Moghaddas, S.1    Hoppel, C.L.2    Lesnefsky, E.J.3
  • 46
    • 0037373449 scopus 로고    scopus 로고
    • Mitochondria from females exhibit higher antioxidant gene expression and lower oxidative damage than males
    • Borrás C, Sastre J, García-Sala D, Lloret A, Pallardó FV, Viña J. Mitochondria from females exhibit higher antioxidant gene expression and lower oxidative damage than males. Free Radic Biol Med. 2003;34:546-552. doi:10.1016/S0891-5849(02)01356-4
    • (2003) Free Radic Biol Med. , vol.34 , pp. 546-552
    • Borrás, C.1    Sastre, J.2    García-Sala, D.3    Lloret, A.4    Pallardó, F.V.5    Viña, J.6
  • 47
    • 33745739747 scopus 로고    scopus 로고
    • Energy deficiency in the failing heart: Linking increased reactive oxygen species and disruption of oxidative phosphorylation rate
    • Sheeran FL, Pepe S. Energy deficiency in the failing heart: linking increased reactive oxygen species and disruption of oxidative phosphorylation rate. Biochim Biophys Acta. 2006;1757:543-552. doi:10.1016/j.bbabio. 2006.03.008
    • (2006) Biochim Biophys Acta. , vol.1757 , pp. 543-552
    • Sheeran, F.L.1    Pepe, S.2
  • 48
    • 0032401496 scopus 로고    scopus 로고
    • The role of oxidative stress in the genesis of heart disease
    • Singal PK, Khaper N, Palace V, Kumar D. The role of oxidative stress in the genesis of heart disease. Cardiovasc Res. 1998;40:426-432. doi:10.1016/S0008-6363(98)00244-2
    • (1998) Cardiovasc Res. , vol.40 , pp. 426-432
    • Singal, P.K.1    Khaper, N.2    Palace, V.3    Kumar, D.4
  • 49
    • 84859884412 scopus 로고    scopus 로고
    • Mitochondria and cardiovascular aging
    • Dai DF, Rabinovitch PS, Ungvari Z. Mitochondria and cardiovascular aging. Circ Res. 2012;110:1109-1124. doi:10.1161/CIRCRESAHA. 111.246140.
    • (2012) Circ Res. , vol.110 , pp. 1109-1124
    • Dai, D.F.1    Rabinovitch, P.S.2    Ungvari, Z.3
  • 50
    • 84863403169 scopus 로고    scopus 로고
    • The caloric restriction paradigm: Implications for healthy human aging
    • Anderson RM, Weindruch R. The caloric restriction paradigm: implications for healthy human aging. Am J Hum Biol. 2012;24:101-106. doi:10.1002/ajhb.22243
    • (2012) Am J Hum Biol. , vol.24 , pp. 101-106
    • Anderson, R.M.1    Weindruch, R.2
  • 51
    • 33846335174 scopus 로고    scopus 로고
    • Modulation of electron transport protects cardiac mitochondria and decreases myocardial injury during ischemia and reperfusion
    • Chen Q, Camara AK, Stowe DF, Hoppel CL, Lesnefsky EJ. Modulation of electron transport protects cardiac mitochondria and decreases myocardial injury during ischemia and reperfusion. Am J Physiol Cell Physiol. 2007;292:C137-C147. doi:10.1152/ajpcell.00270.2006
    • (2007) Am J Physiol Cell Physiol. , vol.292 , pp. C137-C147
    • Chen, Q.1    Camara, A.K.2    Stowe, D.F.3    Hoppel, C.L.4    Lesnefsky, E.J.5
  • 52
    • 80051802678 scopus 로고    scopus 로고
    • Caloric restriction primes mitochondria for ischemic stress by deacetylating specific mitochondrial proteins of the electron transport chain
    • Shinmura K, Tamaki K, Sano M, et al. Caloric restriction primes mitochondria for ischemic stress by deacetylating specific mitochondrial proteins of the electron transport chain. Circ Res. 2011;109:396-406. doi:10.1161/CIRCRESAHA.111.243097
    • (2011) Circ Res. , vol.109 , pp. 396-406
    • Shinmura, K.1    Tamaki, K.2    Sano, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.