Polyethylene glycol modification decreases the cardiac toxicity of carbonaceous dots in mouse and zebrafish models

Acta Pharmacologica Sinica

Volumn 36, Issue 11, 2015, Pages 1349-1355

  Chen, Jian Tao ^b   Sun, Hua Qin ^b   Wang, Wei Liang ^a   Xu, Wen Ming ^b   He, Qin ^b   Shen, Shun ^a   Qian, Jun ^a   Gao, Hui Le ^b  

^a FUDAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONACEOUS DOT; CREATINE KINASE; LACTATE DEHYDROGENASE; MACROGOL; MYOSIN LIGHT CHAIN 2; NANOMATERIAL; UNCLASSIFIED DRUG; CARBON; MACROGOL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BLOOD BIOCHEMISTRY; CARDIOTOXICITY; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; ELECTROCARDIOGRAM; EMBRYO; GENE EXPRESSION; HEART DEVELOPMENT; HEART MUSCLE CELL; HEART RATE; HISTOPATHOLOGY; IN SITU HYBRIDIZATION; MALE; MOUSE; NONHUMAN; ZEBRA FISH; ANIMAL; CHEMICALLY INDUCED; CHEMISTRY; CONGENITAL HEART MALFORMATION; DISEASE MODEL; DRUG EFFECTS; EMBRYOLOGY; HEART; PHYSIOLOGY; TRANSGENIC ANIMAL; ULTRASTRUCTURE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CARBON; CARDIOTOXICITY; DISEASE MODELS, ANIMAL; HEART; HEART DEFECTS, CONGENITAL; HEART RATE; MALE; MICE; NANOSTRUCTURES; POLYETHYLENE GLYCOLS; ZEBRAFISH;

EID: 84946560592     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2015.100     Document Type: Article

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