70-kDa heat shock protein coated magnetic nanocarriers as a nanovaccine for induction of anti-tumor immune response in experimental glioma

Journal of Controlled Release

Volumn 220, Issue , 2015, Pages 329-340

  Shevtsov, Maxim A ^a,b,c,d   Nikolaev, Boris P ^e   Yakovleva, Liudmila Y ^e   Parr, Marina A ^f   Marchenko, Yaroslav Y ^e   Eliseev, Igor ^g   Dobrodumov, Anatolii V ^h   Zlobina, Olga ^e   Zhakhov, Alexander ^e   Ischenko, Alexander M ^e   Pitkin, Emil ⁱ   Multhoff, Gabriele ^d  

^a INSTITUTE OF CYTOLOGY   (Russian Federation)

^b PAVLOV FIRST SAINT PETERSBURG STATE MEDICAL UNIVERSITY   (Russian Federation)

^c Polenov Research Institute of Neurosurgery   (Russian Federation)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e Institute for Highly Pure Biopreparations   (Russian Federation)

^f ST PETERSBURG STATE UNIVERSITY   (Russian Federation)

^g RUSSIAN ACADEMY OF SCIENCES   (Russian Federation)

^h INSTITUTE OF MACROMOLECULAR COMPOUNDS   (Russian Federation)

ⁱ UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Brain tumor; Hsp70; Immunotherapy; Magnetic nanoparticles; Vaccine

Indexed keywords

BINS; CELLS; CYTOLOGY; DISEASES; IMMUNE SYSTEM; MAGNETISM; NANOMAGNETICS; NANOPARTICLES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDES; PROTEINS; RECOMBINANT PROTEINS; T-CELLS; VACCINES;

BRAIN TUMORS; DENDRITIC CELLS (DCS); HSP70; IMMUNOTHERAPY; MAGNETIC NANO-PARTICLES; NUCLEOTIDE-BINDING DOMAIN; SUBSTRATE-BINDING DOMAINS; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES;

TUMORS;

HEAT SHOCK PROTEIN 70; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; CANCER VACCINE; DEXTRAN; DRUG CARRIER; GAMMA INTERFERON; MAGNETITE NANOPARTICLE; SUPERPARAMAGNETIC IRON OXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CD8+ T LYMPHOCYTE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; DENDRITIC CELL; ENZYME LINKED IMMUNOSPOT ASSAY; GLIOMA; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOTHERAPY; IN VITRO STUDY; LYMPHOCYTE; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RAT; TRANSMISSION ELECTRON MICROSCOPY; TUMOR GROWTH; ANIMAL; BLOOD; BRAIN NEOPLASMS; CELLULAR IMMUNITY; CHEMISTRY; COCULTURE; DRUG EFFECTS; DRUG FORMULATION; EXPERIMENTAL MELANOMA; HUMAN; HUMORAL IMMUNITY; IMMUNIZATION; IMMUNOLOGY; K-562 CELL LINE; METABOLISM; MOUSE; NANOMEDICINE; PATHOLOGY; PROTEIN DOMAIN; PROTON NUCLEAR MAGNETIC RESONANCE; TIME FACTOR; TUMOR ASSOCIATED LEUKOCYTE; TUMOR VOLUME; WISTAR RAT;

ANIMALS; BRAIN NEOPLASMS; CANCER VACCINES; COCULTURE TECHNIQUES; DENDRITIC CELLS; DEXTRANS; DRUG CARRIERS; DRUG COMPOUNDING; GLIOMA; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; IMMUNIZATION; INTERFERON-GAMMA; K562 CELLS; LYMPHOCYTES, TUMOR-INFILTRATING; MAGNETIC RESONANCE IMAGING; MAGNETITE NANOPARTICLES; MALE; MELANOMA, EXPERIMENTAL; MICE; NANOMEDICINE; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTON MAGNETIC RESONANCE SPECTROSCOPY; RATS, WISTAR; T-LYMPHOCYTES, CYTOTOXIC; TIME FACTORS; TUMOR BURDEN;

EID: 84946559449     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.10.051     Document Type: Article

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