Th2-M2 immunity in lesions of muscular sarcoidosis and macrophagic myofasciitis

Neuropathology and Applied Neurobiology

Volumn 41, Issue 7, 2015, Pages 952-963

  Preusse, Corinna ^a   Goebel, Hans H ^a,b   Pehl, Debora ^a   Rinnenthal, Jan L ^a   Kley, Rudolf A ^c   Allenbach, Yves ^d,e   Heppner, Frank L ^a   Vorgerd, Matthias ^c   Authier, François Jerôme ^f,g   Gherardi, Romain ^f,g   Stenzel, Werner ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c RUHR UNIVERSITY BOCHUM   (Germany)

^d ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^e SORBONNE UNIVERSITÉ   (France)

^f HENRI MONDOR HOSPITAL   (France)

^g FACULTÉ DE MÉDECINE   (France)

Author keywords

Immunology; Laser microdissection; Macrophagic myofasciitis; Muscle disease; Neuromuscular sarcoidosis

Indexed keywords

CD68 ANTIGEN; CHEMOKINE RECEPTOR CXCR3; GAMMA INTERFERON; MESSENGER RNA; STAT1 PROTEIN; STAT6 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2;

ADULT; AGED; ARTICLE; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; FASCIITIS; FEMALE; FIBROGENESIS; GIANT CELL; GRANULOMA; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; LASER MICRODISSECTION; MACROPHAGE; MACROPHAGE ACTIVATION; MACROPHAGIC MYOFASCIITIS; MALE; MIDDLE AGED; MUSCLE BIOPSY; NEUROMUSCULAR DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARCOIDOSIS; SKELETAL MUSCLE; TH1 CELL; TH2 CELL; YOUNG ADULT; IMMUNOLOGY; MYOSITIS; PATHOLOGY;

ADULT; AGED; FASCIITIS; FEMALE; HUMANS; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MIDDLE AGED; MUSCLE, SKELETAL; MYOSITIS; SARCOIDOSIS; TH2 CELLS; YOUNG ADULT;

EID: 84946494250     PISSN: 03051846     EISSN: 13652990     Source Type: Journal    
DOI: 10.1111/nan.12231     Document Type: Article

References (35)

1. Kool M, Hammad H, Lambrecht BN. Cellular networks controlling Th2 polarization in allergy and immunity. F1000 Biol Rep 2012; 4: 6
2. Marrack P, McKee AS, Munks MW. Towards an understanding of the adjuvant action of aluminium. Nat Rev Immunol 2009; 9: 287-293
3. Hogenesch H. Mechanism of immunopotentiation and safety of aluminum adjuvants. Front Immunol 2012; 3: 406
4. Kanchan V, Panda AK. Interactions of antigen-loaded polylactide particles with macrophages and their correlation with the immune response. Biomaterials 2007; 28: 5344-5357
5. Gherardi RK, Coquet M, Cherin P, Authier FJ, Laforet P, Belec L, Figarella-Branger D, Mussini JM, Pellissier JF, Fardeau M. Macrophagic myofasciitis: an emerging entity. Groupe d'Etudes et Recherche sur les Maladies Musculaires Acquises et Dysimmunitaires (GERMMAD) de l'Association Francaise contre les Myopathies (AFM). Lancet 1998; 352: 347-352
6. Santiago T, Rebelo O, Negrao L, Matos A. Macrophagic myofasciitis and vaccination: consequence or coincidence? Rheumatol Int 2014; 35: 189-192
7. Shivane A, Hilton DA, Moate RM, Bond PR, Endean A. Macrophagic myofasciitis: a report of second case from UK. Neuropathol Appl Neurobiol 2012; 38: 734-736
8. Gherardi RK, Coquet M, Cherin P, Belec L, Moretto P, Dreyfus PA, Pellissier JF, Chariot P, Authier FJ. Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscle. Brain 2001; 124: 1821-1831
9. Israeli E, Agmon-Levin N, Blank M, Shoenfeld Y. Macrophagic myofaciitis a vaccine (alum) autoimmune-related disease. Clin Rev Allergy Immunol 2011; 41: 163-168
10. Prokop S, Heppner FL, Goebel HH, Stenzel W. M2 polarized macrophages and giant cells contribute to myofibrosis in neuromuscular sarcoidosis. Am J Pathol 2011; 178: 1279-1286
11. Hauber HP, Gholami D, Meyer A, Pforte A. Increased interleukin-13 expression in patients with sarcoidosis. Thorax 2003; 58: 519-524
12. Khan Z, Combadiere C, Authier FJ, Itier V, Lux F, Exley C, Mahrouf-Yorgov M, Decrouy X, Moretto P, Tillement O, Gherardi RK, Cadusseau J. Slow CCL2-dependent translocation of biopersistent particles from muscle to brain. BMC Med 2013; 11: 99
13. Kool M, Petrilli V, De Smedt T, Rolaz A, Hammad H, van Nimwegen M, Bergen IM, Castillo R, Lambrecht BN, Tschopp J. Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome. J Immunol 2008; 181: 3755-3759
14. Kool M, Soullie T, van Nimwegen M, Willart MA, Muskens F, Jung S, Hoogsteden HC, Hammad H, Lambrecht BN. Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells. J Exp Med 2008; 205: 869-882
15. Martinez FO, Gordon S. The M1 and M2 paradigm of macrophage activation: time for reassessment. F1000Prime Rep 2014; 6: 13
16. Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, Natoli G, Saeij JP, Schultze JL, Shirey KA, Sica A, Suttles J, Udalova I, van Ginderachter JA, Vogel SN, Wynn TA. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity 2014; 41: 14-20
17. Lawrence T, Natoli G. Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat Rev Immunol 2011; 11: 750-761
18. Preusse C, Goebel HH, Held J, Wengert O, Scheibe F, Irlbacher K, Koch A, Heppner FL, Stenzel W. Immune-mediated necrotizing myopathy is characterized by a specific Th1-m1 polarized immune profile. Am J Pathol 2012; 181: 2161-2171
19. Barron L, Wynn TA. Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophages. Am J Physiol Gastrointest Liver Physiol 2011; 300: G723-728
20. McNally AK, Anderson JM. Foreign body-type multinucleated giant cell formation is potently induced by alpha-tocopherol and prevented by the diacylglycerol kinase inhibitor R59022. Am J Pathol 2003; 163: 1147-1156
21. McNally AK, Anderson JM. Multinucleated giant cell formation exhibits features of phagocytosis with participation of the endoplasmic reticulum. Exp Mol Pathol 2005; 79: 126-135
22. McNally AK, Anderson JM. Foreign body-type multinucleated giant cells induced by interleukin-4 express select lymphocyte co-stimulatory molecules and are phenotypically distinct from osteoclasts and dendritic cells. Exp Mol Pathol 2011; 91: 673-681
23. Helming L, Gordon S. Molecular mediators of macrophage fusion. Trends Cell Biol 2009; 19: 514-522
24. Stein M, Keshav S, Harris N, Gordon S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J Exp Med 1992; 176: 287-292
25. Helming L, Tomasello E, Kyriakides TR, Martinez FO, Takai T, Gordon S, Vivier E. Essential role of DAP12 signaling in macrophage programming into a fusion-competent state. Sci Signal 2008; 1: ra11
26. Paloneva J, Mandelin J, Kiialainen A, Bohling T, Prudlo J, Hakola P, Haltia M, Konttinen YT, Peltonen L. DAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic features. J Exp Med 2003; 198: 669-675
27. Nataf S, Anginot A, Vuaillat C, Malaval L, Fodil N, Chereul E, Langlois JB, Dumontel C, Cavillon G, Confavreux C, Mazzorana M, Vico L, Belin MF, Vivier E, Tomasello E, Jurdic P. Brain and bone damage in KARAP/DAP12 loss-of-function mice correlate with alterations in microglia and osteoclast lineages. Am J Pathol 2005; 166: 275-286
28. Kaifu T, Nakahara J, Inui M, Mishima K, Momiyama T, Kaji M, Sugahara A, Koito H, Ujike-Asai A, Nakamura A, Kanazawa K, Tan-Takeuchi K, Iwasaki K, Yokoyama WM, Kudo A, Fujiwara M, Asou H, Takai T. Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice. J Clin Invest 2003; 111: 323-332
29. Rosenbaum JT, Pasadhika S, Crouser ED, Choi D, Harrington CA, Lewis JA, Austin CR, Diebel TN, Vance EE, Braziel RM, Smith JR, Planck SR. Hypothesis: sarcoidosis is a STAT1-mediated disease. Clin Immunol 2009; 132: 174-183
30. Antoniou KM, Tzouvelekis A, Alexandrakis MG, Tsiligianni I, Tzanakis N, Sfiridaki K, Rachiotis G, Bouros D, Siafakas NM. Upregulation of Th1 cytokine profile (IL-12, IL-18) in bronchoalveolar lavage fluid in patients with pulmonary sarcoidosis. J Interferon Cytokine Res 2006; 26: 400-405
31. Inui N, Chida K, Suda T, Nakamura H. TH1/TH2 and TC1/TC2 profiles in peripheral blood and bronchoalveolar lavage fluid cells in pulmonary sarcoidosis. J Allergy Clin Immunol 2001; 107: 337-344
32. Prasse A, Georges CG, Biller H, Hamm H, Matthys H, Luttmann W, Virchow JC Jr. Th1 cytokine pattern in sarcoidosis is expressed by bronchoalveolar CD4+ and CD8+ T cells. Clin Exp Immunol 2000; 122: 241-248
33. McNally AK, Anderson JM. Interleukin-4 induces foreign body giant cells from human monocytes/macrophages. Differential lymphokine regulation of macrophage fusion leads to morphological variants of multinucleated giant cells. Am J Pathol 1995; 147: 1487-1499
34. Jay SM, Skokos E, Laiwalla F, Krady MM, Kyriakides TR. Foreign body giant cell formation is preceded by lamellipodia formation and can be attenuated by inhibition of Rac1 activation. Am J Pathol 2007; 171: 632-640
35. Authier FJ, Cherin P, Creange A, Bonnotte B, Ferrer X, Abdelmoumni A, Ranoux D, Pelletier J, Figarella-Branger D, Granel B, Maisonobe T, Coquet M, Degos JD, Gherardi RK. Central nervous system disease in patients with macrophagic myofasciitis. Brain 2001; 124: 974-983