Anti-citrullinated protein antibodies promote apoptosis of mature human Saos-2 osteoblasts via cell-surface binding to citrullinated heat shock protein 60

Immunobiology

Volumn 221, Issue 1, 2016, Pages 76-83

  Lu, Ming Chi ^a,b   Yu, Chia Li ^c   Yu, Hui Chun ^a   Huang, Hsien Bin ^d   Koo, Malcolm ^a,e   Lai, Ning Sheng ^a,b  

^a DALIN TZU CHI HOSPITAL   (Taiwan)

^b TZU CHI UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d NATIONAL CHUNG CHENG UNIVERSITY   (Taiwan)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

Anti citrullinated protein antibodies; Apoptosis; Dheumatoid arthritis; Heat shock protein 60; Osteoblast

Indexed keywords

CHAPERONIN 60; CITRULLINATED HEAT SHOCK PROTEIN 60; CITRULLINATED HEAT SHOCK PROTEIN 60 ANTIBODY; CYCLIC CITRULLINATED PEPTIDE ANTIBODY; HEAT SHOCK PROTEIN 60 ANTIBODY; INTERLEUKIN 6; INTERLEUKIN 8; PROTEIN ANTIBODY; RECOMBINANT HEAT SHOCK PROTEIN 60; RECOMBINANT PROTEIN; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; AUTOANTIBODY; AUTOANTIGEN; CITRULLINE; HSPD1 PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; MITOCHONDRIAL PROTEIN; PROTEIN BINDING; TLR4 PROTEIN, HUMAN;

ADULT; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ANTIBODY TITER; ANTIGEN BINDING; APOPTOSIS; ARTICLE; CELL MATURATION; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MOLECULAR CLONING; OSTEOBLAST; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEOMICS; RHEUMATOID ARTHRITIS; SAOS 2 CELL LINE; SIGNAL TRANSDUCTION; AGED; BIOSYNTHESIS; CASE CONTROL STUDY; CELL LINE; DRUG EFFECTS; GENETICS; IMMUNOLOGY; JOINT; METABOLISM; MIDDLE AGED; PATHOLOGY; PROTEIN PROCESSING;

ADULT; AGED; APOPTOSIS; ARTHRITIS, RHEUMATOID; AUTOANTIBODIES; AUTOANTIGENS; CASE-CONTROL STUDIES; CELL LINE; CHAPERONIN 60; CITRULLINE; CLONING, MOLECULAR; FEMALE; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; JOINTS; MALE; MIDDLE AGED; MITOCHONDRIAL PROTEINS; OSTEOBLASTS; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; TOLL-LIKE RECEPTOR 4;

EID: 84946492505     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2015.07.019     Document Type: Article

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