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Volumn 10, Issue 6, 2015, Pages

CXCL8 and CCL20 enhance osteoclastogenesis via modulation of cytokine production by human primary osteoblasts

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; INTERLEUKIN 6; INTERLEUKIN 8; KI 67 ANTIGEN; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MESSENGER RNA; CCL20 PROTEIN, HUMAN; CCR6 PROTEIN, HUMAN; CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CXCR1; CONDITIONED MEDIUM; CYTOKINE; IL6 PROTEIN, HUMAN; IL8 PROTEIN, HUMAN; SCLEROPROTEIN; TUMOR NECROSIS FACTOR;

EID: 84939145811     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0131041     Document Type: Article
Times cited : (40)

References (48)
  • 1
    • 71249128757 scopus 로고    scopus 로고
    • Extra-articular manifestations
    • 19822047
    • Mielants H, Van den Bosch F. Extra-articular manifestations. Clin Exp Rheumatol 2009;27:S56-S61. PMID:19822047
    • (2009) Clin Exp Rheumatol , vol.27 , pp. S56-S61
    • Mielants, H.1    Van Den Bosch, F.2
  • 3
    • 84885433329 scopus 로고    scopus 로고
    • Can bone loss in rheumatoid arthritis be prevented?
    • 23775419
    • Vis M, Güler-Yüksel, Lems WF. Can bone loss in rheumatoid arthritis be prevented? Osteoporos Int 2013;10:2541-2553. doi:10.1007/s00198-013-2334-5 PMID:23775419
    • (2013) Osteoporos Int , vol.10 , pp. 2541-2553
    • Vis, M.1    Güler-Yüksel2    Lems, W.F.3
  • 4
    • 48749116547 scopus 로고    scopus 로고
    • Focal and generalized bone loss in rheumatoid arthritis: Separate or similar concepts?
    • 18594493
    • Haugeberg G. Focal and generalized bone loss in rheumatoid arthritis: separate or similar concepts? Nat Clin Pract Rheumatol 2008;4:402-403. doi:10.1038/ncprheum0843 PMID:18594493
    • (2008) Nat Clin Pract Rheumatol , vol.4 , pp. 402-403
    • Haugeberg, G.1
  • 5
    • 84919462289 scopus 로고    scopus 로고
    • Inflammatory factors in the circulation of patients with active rheumatoid arthritis stimulate osteoclastogenesis via endogenous cytokine production by osteoblasts
    • 25027107
    • Pathak JL, Bravenboer N, Verschueren P, Lems WF, Luyten FP, Klein-Nulend J et al. Inflammatory factors in the circulation of patients with active rheumatoid arthritis stimulate osteoclastogenesis via endogenous cytokine production by osteoblasts. Osteoporos Int 2014;25:2453-2463. doi:10.1007/s00198-014-2779-1 PMID:25027107
    • (2014) Osteoporos Int , vol.25 , pp. 2453-2463
    • Pathak, J.L.1    Bravenboer, N.2    Verschueren, P.3    Lems, W.F.4    Luyten, F.P.5    Klein-Nulend, J.6
  • 6
    • 0029876121 scopus 로고    scopus 로고
    • Role of cytokines in rheumatoid arthritis
    • 8717520
    • Feldmann M, Brennan FM, Maini RN. Role of cytokines in rheumatoid arthritis. Ann Rev Immunol 1996;14:397-440. PMID:8717520
    • (1996) Ann Rev Immunol , vol.14 , pp. 397-440
    • Feldmann, M.1    Brennan, F.M.2    Maini, R.N.3
  • 7
    • 70450170213 scopus 로고    scopus 로고
    • Proinflammatory cytokines synergistically enhance the production of chemokine ligand 20 (CCL20) from rheumatoid fibroblastlike synovial cells in vitro and serum CCL20 is reduced in vivo by biologic disease-modifying antirheumatic drugs
    • 19797510
    • Kawashiri SY, Kawakami A, Iwamoto N, Fujikawa K, Aramaki T, Tamai M, et al. Proinflammatory cytokines synergistically enhance the production of chemokine ligand 20 (CCL20) from rheumatoid fibroblastlike synovial cells in vitro and serum CCL20 is reduced in vivo by biologic disease-modifying antirheumatic drugs. J Rheumatol 2009;36:2397-2402. doi:10.3899/jrheum.090132 PMID:19797510
    • (2009) J Rheumatol , vol.36 , pp. 2397-2402
    • Kawashiri, S.Y.1    Kawakami, A.2    Iwamoto, N.3    Fujikawa, K.4    Aramaki, T.5    Tamai, M.6
  • 8
    • 76649115291 scopus 로고    scopus 로고
    • CXCL 9 and CXCL 10 as sensitive markers of disease activity in patients with rheumatoid arthritis
    • 20032101
    • Kuan WP, Tam LS, Wong CK, Ko FW, Li T, Zhu T, et al. CXCL 9 and CXCL 10 as sensitive markers of disease activity in patients with rheumatoid arthritis. J Rheumatol 2010;37:257-264. doi:10.3899/jrheum.090769 PMID:20032101
    • (2010) J Rheumatol , vol.37 , pp. 257-264
    • Kuan, W.P.1    Tam, L.S.2    Wong, C.K.3    Ko, F.W.4    Li, T.5    Zhu, T.6
  • 9
    • 0026770902 scopus 로고
    • Production of various cytokines by normal human osteoblastlike cells in response to interleukin-1 beta and tumor necrosis factor-alpha: Lack of regulation by 17 beta-estradiol
    • 1572280
    • Chaudhary LR, Spelsberg TC, Riggs BL. Production of various cytokines by normal human osteoblastlike cells in response to interleukin-1 beta and tumor necrosis factor-alpha: lack of regulation by 17 beta-estradiol. Endocrinology 1992;130:2528-2534. PMID:1572280
    • (1992) Endocrinology , vol.130 , pp. 2528-2534
    • Chaudhary, L.R.1    Spelsberg, T.C.2    Riggs, B.L.3
  • 10
    • 0032588998 scopus 로고    scopus 로고
    • Interleukin-1beta and tumor necrosis factor-alpha but not interleukin-6 stimulate osteoprotegerin ligand gene expression in human osteoblastic cells
    • 10495128
    • Hofbauer LC, Lacey DL, Dunstan CR, Spelsberg TC, Riggs BL, Khosla S. Interleukin-1beta and tumor necrosis factor-alpha but not interleukin-6 stimulate osteoprotegerin ligand gene expression in human osteoblastic cells. Bone 1999;25:255-259. PMID:10495128
    • (1999) Bone , vol.25 , pp. 255-259
    • Hofbauer, L.C.1    Lacey, D.L.2    Dunstan, C.R.3    Spelsberg, T.C.4    Riggs, B.L.5    Khosla, S.6
  • 11
    • 0033768507 scopus 로고    scopus 로고
    • Expression of osteoclast differentiation factor in rheumatoid arthritis
    • 11083276
    • Shigeyama Y, Pap T, Kunzler P, Simmen BR, Gay RE, Gay S. Expression of osteoclast differentiation factor in rheumatoid arthritis. Arthr Rheum 2000;43:2523-2530. PMID:11083276
    • (2000) Arthr Rheum , vol.43 , pp. 2523-2530
    • Shigeyama, Y.1    Pap, T.2    Kunzler, P.3    Simmen, B.R.4    Gay, R.E.5    Gay, S.6
  • 12
    • 0028305241 scopus 로고
    • Generalized bone loss in patients with early rheumatoid arthritis
    • 7912297
    • Gough AK, Lilley J, Eyre S, Holder RL, Emery P. Generalized bone loss in patients with early rheumatoid arthritis. Lancet 1994;344:23-27. PMID:7912297
    • (1994) Lancet , vol.344 , pp. 23-27
    • Gough, A.K.1    Lilley, J.2    Eyre, S.3    Holder, R.L.4    Emery, P.5
  • 13
    • 55849095891 scopus 로고    scopus 로고
    • Evidence that cytokines play a role in rheumatoid arthritis
    • 18982160
    • Brennan FM, McInnes IB. Evidence that cytokines play a role in rheumatoid arthritis. J Clin Invest 2008;118:3537-3545. doi:10.1172/JCI36389 PMID:18982160
    • (2008) J Clin Invest , vol.118 , pp. 3537-3545
    • Brennan, F.M.1    McInnes, I.B.2
  • 14
    • 84868473102 scopus 로고    scopus 로고
    • Bone erosion in rheumatoid arthritis: Mechanisms, diagnosis and treatment
    • 23007741
    • Schett G, Gravallese E. Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment. Nat Rev Rheumatol 2012;8:656-664. doi:10.1038/nrrheum.2012.153 PMID:23007741
    • (2012) Nat Rev Rheumatol , vol.8 , pp. 656-664
    • Schett, G.1    Gravallese, E.2
  • 15
    • 70350523970 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha and interleukin-1beta modulate calcium and nitric oxide signaling in mechanically stimulated osteocytes
    • 19877030
    • Bakker AD, Silva VC, Krishnan R, Bacabac RG, Blaauboer ME, Lin YC, et al. Tumor necrosis factor alpha and interleukin-1beta modulate calcium and nitric oxide signaling in mechanically stimulated osteocytes. Arthr Rheum 2009;11:3336-3345. doi:10.1002/art.24920 PMID:19877030
    • (2009) Arthr Rheum , vol.11 , pp. 3336-3345
    • Bakker, A.D.1    Silva, V.C.2    Krishnan, R.3    Bacabac, R.G.4    Blaauboer, M.E.5    Lin, Y.C.6
  • 16
    • 0035256994 scopus 로고    scopus 로고
    • Chemokines: Immunology's high impact factors
    • 11175800
    • Mackay CR. Chemokines: Immunology's high impact factors. Nat Immunol 2001;2:95-101. PMID:11175800
    • (2001) Nat Immunol , vol.2 , pp. 95-101
    • Mackay, C.R.1
  • 17
    • 0034080318 scopus 로고    scopus 로고
    • The biology of chemokines and their receptors
    • Rossi D, Zlotnik A. The biology of chemokines and their receptors. Ann Rev Immunol 2000;18:217-242.
    • (2000) Ann Rev Immunol , vol.18 , pp. 217-242
    • Rossi, D.1    Zlotnik, A.2
  • 18
    • 0037211817 scopus 로고    scopus 로고
    • Human osteoblasts express functional CXC chemokine receptors 3 and 5: Activation by their ligands, CXCL10 and CXCL13, significantly induces alkaline phosphatase and beta-N-acetylhexosaminidase release
    • 12447991
    • Lisignoli G, Toneguzzi S, Piacentini A, Cattini L, Lenti A, Tschon M, et al. Human osteoblasts express functional CXC chemokine receptors 3 and 5: activation by their ligands, CXCL10 and CXCL13, significantly induces alkaline phosphatase and beta-N-acetylhexosaminidase release. J Cell Physiol 2003;194:71-79. PMID:12447991
    • (2003) J Cell Physiol , vol.194 , pp. 71-79
    • Lisignoli, G.1    Toneguzzi, S.2    Piacentini, A.3    Cattini, L.4    Lenti, A.5    Tschon, M.6
  • 19
    • 33846614551 scopus 로고    scopus 로고
    • CCL20 chemokine induces both osteoblast proliferation and osteoclast differentiation: Increased levels of CCL20 are expressed in subchondral bone tissue of rheumatoid arthritis patients
    • 17133360
    • Lisignoli G, Piacentini A, Cristino S, Grassi F, Cavallo C, Cattini L, et al. CCL20 chemokine induces both osteoblast proliferation and osteoclast differentiation: Increased levels of CCL20 are expressed in subchondral bone tissue of rheumatoid arthritis patients. J Cell Physiol 2007;210:798-806. PMID:17133360
    • (2007) J Cell Physiol , vol.210 , pp. 798-806
    • Lisignoli, G.1    Piacentini, A.2    Cristino, S.3    Grassi, F.4    Cavallo, C.5    Cattini, L.6
  • 20
    • 69249224531 scopus 로고    scopus 로고
    • CCL20/CCR6 chemokine/receptor expression in bone tissue from osteoarthritis and rheumatoid arthritis patients: Different response of osteoblasts in the two groups
    • 19492413
    • Lisignoli G, Manferdini C, Codeluppi K, Piacentini A, Grassi F, Cattini L, et al. CCL20/CCR6 chemokine/receptor expression in bone tissue from osteoarthritis and rheumatoid arthritis patients: different response of osteoblasts in the two groups. J Cell Physiol 2009;221:154-160. doi:10.1002/jcp. 21839 PMID:19492413
    • (2009) J Cell Physiol , vol.221 , pp. 154-160
    • Lisignoli, G.1    Manferdini, C.2    Codeluppi, K.3    Piacentini, A.4    Grassi, F.5    Cattini, L.6
  • 21
    • 17744395542 scopus 로고    scopus 로고
    • Functional expression of beta-chemokine receptors in osteoblasts: Role of regulated upon activation, normal T cell expressed and secreted (RANTES) in osteoblasts and regulation of its secretion by osteoblasts and osteoclasts
    • 15718270
    • Yano S, Mentaverri R, Kanuparthi D, Bandyopadhyay S, Rivera A, Brown EM, et al. Functional expression of beta-chemokine receptors in osteoblasts: role of regulated upon activation, normal T cell expressed and secreted (RANTES) in osteoblasts and regulation of its secretion by osteoblasts and osteoclasts. Endocrinology 2005;146:2324-2335. PMID:15718270
    • (2005) Endocrinology , vol.146 , pp. 2324-2335
    • Yano, S.1    Mentaverri, R.2    Kanuparthi, D.3    Bandyopadhyay, S.4    Rivera, A.5    Brown, E.M.6
  • 22
    • 28844487770 scopus 로고    scopus 로고
    • Extravasation into synovial tissue induces CCL20 mRNA expression in polymorphonuclear neutrophils of patients with rheumatoid arthritis
    • 16331752
    • Schlenk J, Lorenz HM, Haas JP, Herrmann M, Hohenberger G, Kalden JR, et al. Extravasation into synovial tissue induces CCL20 mRNA expression in polymorphonuclear neutrophils of patients with rheumatoid arthritis. J Rheumatol 2005;32:2291-2298. PMID:16331752
    • (2005) J Rheumatol , vol.32 , pp. 2291-2298
    • Schlenk, J.1    Lorenz, H.M.2    Haas, J.P.3    Herrmann, M.4    Hohenberger, G.5    Kalden, J.R.6
  • 23
    • 78549271154 scopus 로고    scopus 로고
    • Increased IL-17 production by peripheral T helper cells after tumor necrosis factor blockade in rheumatoid arthritis is accompanied by inhibition of migration-associated chemokine receptor expression
    • Aerts NE, De Knop KJ, Leysen J, Ebo DG, Bridts CH, Weyler JJ, et al. Increased IL-17 production by peripheral T helper cells after tumor necrosis factor blockade in rheumatoid arthritis is accompanied by inhibition of migration-associated chemokine receptor expression. Rheumatol 2010;49:2264-2272.
    • (2010) Rheumatol , vol.49 , pp. 2264-2272
    • Aerts, N.E.1    De Knop, K.J.2    Leysen, J.3    Ebo, D.G.4    Bridts, C.H.5    Weyler, J.J.6
  • 25
    • 84861043646 scopus 로고    scopus 로고
    • Bone cells from patients with quiescent Crohn's disease show a reduced growth potential and an impeded maturation
    • 22535626
    • Oostlander AE, Bravenboer N, van Essen HW, Klein-Nulend J, Lems WF, Schulten BA, et al. Bone cells from patients with quiescent Crohn's disease show a reduced growth potential and an impeded maturation. J Cell Biochem 2012;113:2424-2431. doi:10.1002/jcb.24119 PMID:22535626
    • (2012) J Cell Biochem , vol.113 , pp. 2424-2431
    • Oostlander, A.E.1    Bravenboer, N.2    Van Essen, H.W.3    Klein-Nulend, J.4    Lems, W.F.5    Schulten, B.A.6
  • 26
    • 67449131896 scopus 로고    scopus 로고
    • Intercellular adhesion molecule-1 clusters during osteoclastogenesis
    • 19501575
    • Bloemen V, de Vries TJ, Schoenmaker T, Everts V. Intercellular adhesion molecule-1 clusters during osteoclastogenesis. Biochem Biophys Res Commun 2009;385:640-645. doi:10.1016/j.bbrc.2009.05. 145 PMID:19501575
    • (2009) Biochem Biophys Res Commun , vol.385 , pp. 640-645
    • Bloemen, V.1    De Vries, T.J.2    Schoenmaker, T.3    Everts, V.4
  • 27
    • 65549145064 scopus 로고    scopus 로고
    • The Src inhibitor AZD0530 reversibly inhibits the formation and activity of human osteoclasts
    • 19372577
    • de Vries TJ, Mullender MG, van Duin MA, Semeins CM, James N, Green TP, et al. The Src inhibitor AZD0530 reversibly inhibits the formation and activity of human osteoclasts. Mol Cancer Res 2009;7:476-488. doi:10.1158/1541-7786. MCR-08-0219 PMID:19372577
    • (2009) Mol Cancer Res , vol.7 , pp. 476-488
    • De Vries, T.J.1    Mullender, M.G.2    Van Duin, M.A.3    Semeins, C.M.4    James, N.5    Green, T.P.6
  • 28
    • 0031860349 scopus 로고    scopus 로고
    • Response of normal and osteoporotic human bone cells to mechanical stress in vitro
    • 9611164
    • Sterck JG, Klein-Nulend J, Lips P, Burger EH. Response of normal and osteoporotic human bone cells to mechanical stress in vitro. Am J Physol 1998;274:E1113-1120. PMID:9611164
    • (1998) Am J Physol , vol.274 , pp. E1113-E1120
    • Sterck, J.G.1    Klein-Nulend, J.2    Lips, P.3    Burger, E.H.4
  • 30
    • 23744506557 scopus 로고    scopus 로고
    • Additive effects of estrogen and mechanical stress on nitric oxide and prostaglandin E2 production by bone cells from osteoporotic donors
    • 15551057
    • Bakker AD, Klein-Nulend J, Tanck E, Albers GH, Lips P, Burger EH. Additive effects of estrogen and mechanical stress on nitric oxide and prostaglandin E2 production by bone cells from osteoporotic donors. Osteoporos Int 2005;16:983-989. PMID:15551057
    • (2005) Osteoporos Int , vol.16 , pp. 983-989
    • Bakker, A.D.1    Klein-Nulend, J.2    Tanck, E.3    Albers, G.H.4    Lips, P.5    Burger, E.H.6
  • 31
    • 33646863240 scopus 로고    scopus 로고
    • Different responsiveness to mechanical stress of bone cells from osteoporotic versus osteoarthritic donors
    • 16565787
    • Bakker AD, Klein-Nulend J, Tanck E, Heyligers IC, Albers GH, Lips P, et al. Different responsiveness to mechanical stress of bone cells from osteoporotic versus osteoarthritic donors. Osteoporos Int 2006;17:827-833. PMID:16565787
    • (2006) Osteoporos Int , vol.17 , pp. 827-833
    • Bakker, A.D.1    Klein-Nulend, J.2    Tanck, E.3    Heyligers, I.C.4    Albers, G.H.5    Lips, P.6
  • 32
    • 0036025413 scopus 로고    scopus 로고
    • IL-1beta regulates cellular proliferation, prostaglandin E2 synthesis, plasminogen activator activity, osteocalcin production, and bone resorptive activity of the mouse calvarial bone cells
    • 12375736
    • Kim CH, Kang BS, Lee TK, Park WH, Kim JK, Park YG, et al. IL-1beta regulates cellular proliferation, prostaglandin E2 synthesis, plasminogen activator activity, osteocalcin production, and bone resorptive activity of the mouse calvarial bone cells. Immunopharmacol Immunotoxicol 2002;24:395-407. PMID:12375736
    • (2002) Immunopharmacol Immunotoxicol , vol.24 , pp. 395-407
    • Kim, C.H.1    Kang, B.S.2    Lee, T.K.3    Park, W.H.4    Kim, J.K.5    Park, Y.G.6
  • 33
    • 0033695186 scopus 로고    scopus 로고
    • Inhibition of osteoblast differentiation by tumor necrosis factor-alpha
    • 11089525
    • Gilbert L, He X, Farmer P, Boden S, Kozlowaski M, Rubin J, et al. Inhibition of osteoblast differentiation by tumor necrosis factor-alpha. Endocrinology 2000;141:3956-3964. PMID:11089525
    • (2000) Endocrinology , vol.141 , pp. 3956-3964
    • Gilbert, L.1    He, X.2    Farmer, P.3    Boden, S.4    Kozlowaski, M.5    Rubin, J.6
  • 34
    • 0022648104 scopus 로고
    • Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors
    • 3511389
    • Bertolini DR, Nedwin GE, Bringman TS, Smith DD, Mundy GR. Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors. Nature 1986;319:516-518. PMID:3511389
    • (1986) Nature , vol.319 , pp. 516-518
    • Bertolini, D.R.1    Nedwin, G.E.2    Bringman, T.S.3    Smith, D.D.4    Mundy, G.R.5
  • 35
    • 59049085396 scopus 로고    scopus 로고
    • Cathepsin K activity-dependent regulation of osteoclast actin ring formation and bone resorption
    • 19028686
    • Wilson SR, Peters C, Saftig P, Brömme D. Cathepsin K activity-dependent regulation of osteoclast actin ring formation and bone resorption. J Biol Chem 2009;284:2584-2592. doi:10.1074/jbc. M805280200 PMID:19028686
    • (2009) J Biol Chem , vol.284 , pp. 2584-2592
    • Wilson, S.R.1    Peters, C.2    Saftig, P.3    Brömme, D.4
  • 36
    • 84896748731 scopus 로고    scopus 로고
    • Lysophosphatidic acid receptor type 1 (LPA1) plays a functional role in osteoclast differentiation and bone resorption activity
    • 24429286
    • David M, Machuca-Gayet I, Kikuta J, Ottewell P, Mima F, Leblanc R, et al. Lysophosphatidic acid receptor type 1 (LPA1) plays a functional role in osteoclast differentiation and bone resorption activity. J Biol Chem 2014;289:6551-6564. doi:10.1074/jbc. M113.533232 PMID:24429286
    • (2014) J Biol Chem , vol.289 , pp. 6551-6564
    • David, M.1    Machuca-Gayet, I.2    Kikuta, J.3    Ottewell, P.4    Mima, F.5    Leblanc, R.6
  • 37
    • 0035951282 scopus 로고    scopus 로고
    • Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man
    • 11207362
    • Kornak U, Kasper D, Bosl MR, Kaiser E, Schweizer M, Schulz A, et al. Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man. Cell 2001;104:205-215. PMID:11207362
    • (2001) Cell , vol.104 , pp. 205-215
    • Kornak, U.1    Kasper, D.2    Bosl, M.R.3    Kaiser, E.4    Schweizer, M.5    Schulz, A.6
  • 38
    • 41549143872 scopus 로고    scopus 로고
    • Intracellular ClC-3 chloride channels promote bone resorption in vitro through organelle acidification in mouse osteoclasts
    • 18234851
    • Okamoto F, Kajiya H, Toh K, Uchida S, Yoshikawa M, Sasaki S et al. Intracellular ClC-3 chloride channels promote bone resorption in vitro through organelle acidification in mouse osteoclasts. Am J Physiol Cell Physiol 2008;294:C693-C701. doi:10.1152/ajpcell.00251.2007 PMID:18234851
    • (2008) Am J Physiol Cell Physiol , vol.294 , pp. C693-C701
    • Okamoto, F.1    Kajiya, H.2    Toh, K.3    Uchida, S.4    Yoshikawa, M.5    Sasaki, S.6
  • 39
    • 84899459795 scopus 로고    scopus 로고
    • CCR6 and CCL20: Emerging players in the pathogenesis of rheumatoid arthritis
    • 24394994
    • Lee AY, Körner H. CCR6 and CCL20: emerging players in the pathogenesis of rheumatoid arthritis. Immunol Cell Biol 2014;92:354-358. doi:10.1038/icb.2013.97 PMID:24394994
    • (2014) Immunol Cell Biol , vol.92 , pp. 354-358
    • Lee, A.Y.1    Körner, H.2
  • 40
    • 33750953842 scopus 로고    scopus 로고
    • Impaired skeletal development in interleukin-6-transgenic mice: A model for the impact of chronic inflammation on the growing skeletal system
    • De Benedetti F, Rucci N, Del Fattore A, Peruzzi B, Paro R, Longo M, et al. Impaired skeletal development in interleukin-6-transgenic mice: a model for the impact of chronic inflammation on the growing skeletal system. Arthr Rheum 2006;54:3551-3563.
    • (2006) Arthr Rheum , vol.54 , pp. 3551-3563
    • De Benedetti, F.1    Rucci, N.2    Del Fattore, A.3    Peruzzi, B.4    Paro, R.5    Longo, M.6
  • 41
    • 84925549112 scopus 로고    scopus 로고
    • The paradigm of IL-6: From basic science to medicine
    • Naka T, Nishimoto N, Kishimoto T. The paradigm of IL-6: from basic science to medicine. Arthr Res 2002;4:S233-S242.
    • (2002) Arthr Res , vol.4 , pp. S233-S242
    • Naka, T.1    Nishimoto, N.2    Kishimoto, T.3
  • 42
    • 77952672784 scopus 로고    scopus 로고
    • Role for interleukin-6 in structural joint damage and systemic bone loss in rheumatoid arthritis
    • Le Goff B, Blanchard F, Berthelot JM, Heymann D, Maugars Y. Role for interleukin-6 in structural joint damage and systemic bone loss in rheumatoid arthritis. Jt Bone Spine 2010;77:201-205.
    • (2010) Jt Bone Spine , vol.77 , pp. 201-205
    • Le Goff, B.1    Blanchard, F.2    Berthelot, J.M.3    Heymann, D.4    Maugars, Y.5
  • 43
    • 0033304730 scopus 로고    scopus 로고
    • Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
    • 10368775
    • Suda T, Takahashi N, Udagawa N, Jimi E, Gillespie MT, Martin TJ. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev 1999;20:345-357. PMID:10368775
    • (1999) Endocr Rev , vol.20 , pp. 345-357
    • Suda, T.1    Takahashi, N.2    Udagawa, N.3    Jimi, E.4    Gillespie, M.T.5    Martin, T.J.6
  • 44
    • 0025867043 scopus 로고
    • Elevation of interleukin-8 (IL-8) levels in joint fluids of patients with rheumatoid arthritis and the induction by IL-8 of leukocyte infiltration and synovitis in rabbit joints
    • 1932367
    • Endo H, Akahoshi T, Takagishi K, Kashiwazaki S, Matsushima K. Elevation of interleukin-8 (IL-8) levels in joint fluids of patients with rheumatoid arthritis and the induction by IL-8 of leukocyte infiltration and synovitis in rabbit joints. Lymphokine Cytokine Res 1991;10:245-252. PMID:1932367
    • (1991) Lymphokine Cytokine Res , vol.10 , pp. 245-252
    • Endo, H.1    Akahoshi, T.2    Takagishi, K.3    Kashiwazaki, S.4    Matsushima, K.5
  • 45
    • 0035100792 scopus 로고    scopus 로고
    • The development of clinical signs of rheumatoid synovial inflammation is associated with increased synthesis of the chemokine CXCL8 (interleukin-8)
    • 11178128
    • Kraan MC, Patel DD, Haringman JJ, Smith MD, Weedon H, Ahern MJ et al. The development of clinical signs of rheumatoid synovial inflammation is associated with increased synthesis of the chemokine CXCL8 (interleukin-8). Arthritis Res 2001;3:65-71. PMID:11178128
    • (2001) Arthritis Res , vol.3 , pp. 65-71
    • Kraan, M.C.1    Patel, D.D.2    Haringman, J.J.3    Smith, M.D.4    Weedon, H.5    Ahern, M.J.6
  • 47
    • 72949103055 scopus 로고    scopus 로고
    • Pharmacological targeting reveals distinct roles for CXCR2/CXCR1 and CCR2 in a mouse model of arthritis
    • 20004647
    • Min SH, Wang Y, Gonsiorek W, Anilkumar G, Kozlowski J, Lundell D, et al. Pharmacological targeting reveals distinct roles for CXCR2/CXCR1 and CCR2 in a mouse model of arthritis. Biochem Biophys Res Commun 2010;391:1080-1086. doi:10.1016/j.bbrc.2009.12.025 PMID:20004647
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 1080-1086
    • Min, S.H.1    Wang, Y.2    Gonsiorek, W.3    Anilkumar, G.4    Kozlowski, J.5    Lundell, D.6
  • 48
    • 77952885768 scopus 로고    scopus 로고
    • A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility
    • 20453841
    • Kochi Y, Okada Y, Suzuki A, Ikari K, Terao C, Takahashi A, et al. A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility. Nat Genet 2010;42:515-519. doi:10.1038/ng.583 PMID:20453841
    • (2010) Nat Genet , vol.42 , pp. 515-519
    • Kochi, Y.1    Okada, Y.2    Suzuki, A.3    Ikari, K.4    Terao, C.5    Takahashi, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.