Single Molecule Cluster Analysis dissects splicing pathway conformational dynamics

Nature Methods

Volumn 12, Issue 11, 2015, Pages 1077-1084

  Blanco, Mario R ^a,d   Martin, Joshua S ^b,e   Kahlscheuer, Matthew L ^a   Krishnan, Ramya ^a   Abelson, John ^c   Laederach, Alain ^b   Walter, Nils G ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d California Institute of Technology   (United States)

^e NATIONAL EVOLUTIONARY SYNTHESIS CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CWC25 PROTEIN; FUNGAL RNA; MESSENGER RNA PRECURSOR; PRP2 PROTEIN; RECOMBINANT PROTEIN; SPP2 PROTEIN; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; FLUORESCENT DYE; MESSENGER RNA; RNA PRECURSOR; RNA SPLICING;

ALGORITHM; ARTICLE; CATALYSIS; CLADISTICS; CLUSTER ANALYSIS; CONFORMATIONAL TRANSITION; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIDDEN MARKOV MODEL; HISTOGRAM; KINETICS; NONHUMAN; PRIORITY JOURNAL; RNA CONFORMATION; SIGNAL NOISE RATIO; SINGLE MOLECULE CLUSTER ANALYSIS; SPLICEOSOME; WILD TYPE; CHEMISTRY; COMPUTER SIMULATION; CONFORMATION; ENZYME ACTIVE SITE; HUMAN; INTRON; MARKOV CHAIN; MUTATION; RNA SPLICING;

ADENOSINE TRIPHOSPHATE; CATALYTIC DOMAIN; CLUSTER ANALYSIS; COMPUTER SIMULATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT DYES; HUMANS; INTRONS; MARKOV CHAINS; MUTATION; NUCLEIC ACID CONFORMATION; RNA PRECURSORS; RNA SPLICE SITES; RNA SPLICING; RNA, MESSENGER; SPLICEOSOMES;

EID: 84946484798     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.3602     Document Type: Article

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