Low eicosapentaenoic acid to arachidonic acid ratio is associated with thin-cap fibroatheroma determined by optical coherence tomography

Journal of Cardiology

Volumn 66, Issue 6, 2015, Pages 482-488

  Wakabayashi, Yasushi ^a   Funayama, Hiroshi ^a   Ugata, Yusuke ^a   Taniguchi, Yosuke ^a   Hoshino, Hirotaka ^a   Ako, Junya ^b   Momomura, Shin ichi ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b KITASATO UNIVERSITY HOSPITAL   (Japan)

Author keywords

Eicosapentaenoic acid; Optical coherence tomography; Thin cap fibroatheroma

Indexed keywords

ACETYLSALICYLIC ACID; ARACHIDONIC ACID; CLOPIDOGREL; HEPARIN; ICOSAPENTAENOIC ACID;

ACUTE CORONARY SYNDROME; ADULT; AGED; ANGIOCARDIOGRAPHY; ARTICLE; ATHEROMA; CARDIOVASCULAR PARAMETERS; CONFIDENCE INTERVAL; CONTROLLED STUDY; EICOSAPENTAENOIC ACID TO ARACHIDONIC ACID RATIO; FEMALE; HEART CATHETERIZATION; HUMAN; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; OPTICAL COHERENCE TOMOGRAPHY; PERCUTANEOUS CORONARY INTERVENTION; RECEIVER OPERATING CHARACTERISTIC; THIN CAP FIBROATHEROMA; BLOOD; COMPLICATION; FIBROSIS; MIDDLE AGED; ODDS RATIO; PATHOLOGY; PLAQUE, ATHEROSCLEROTIC; PREDICTIVE VALUE; PROCEDURES; STATISTICAL MODEL;

ACUTE CORONARY SYNDROME; AGED; ARACHIDONIC ACID; EICOSAPENTAENOIC ACID; FEMALE; FIBROSIS; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; ODDS RATIO; PERCUTANEOUS CORONARY INTERVENTION; PLAQUE, ATHEROSCLEROTIC; PREDICTIVE VALUE OF TESTS; ROC CURVE; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 84946477494     PISSN: 09145087     EISSN: 18764738     Source Type: Journal    
DOI: 10.1016/j.jjcc.2015.01.008     Document Type: Article

References (27)

1. Kromhout D., Bosschieter E.B., de Lezenne Coulander C. The inverse relation between fish consumption and 20-year mortality from coronary heart disease. N Engl J Med 1985, 312:1205-1209.
2. Yokoyama M., Origasa H., Matsuzaki M., Matsuzawa Y., Saito Y., Ishikawa Y., Oikawa S., Sasaki J., Hishida H., Itakura H., Kita T., Kitabatake A., Nakaya N., Sakata T., Shimada K., et al. Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis. Lancet 2007, 369:1090-1098.
3. Matsuzaki M., Yokoyama M., Saito Y., Origasa H., Ishikawa Y., Oikawa S., Sasaki J., Hishida H., Itakura H., Kita T., Kitabatake A., Nakaya N., Sakata T., Shimada K., Shirato K., et al. Incremental effects of eicosapentaenoic acid on cardiovascular events in statin-treated patients with coronary artery disease. Circ J 2009, 73:1283-1290.
4. Serikawa T., Miura S., Okabe M., Hongo H., Tokutome M., Yoshikawa T., Takesue K., Adachi S., Osaka K., Matsukawa R., Yanagi D., Nozoe M., Kozai T., Hironaga K., Saku K., et al. Ratio of eicosapentaenoic acid to arachidonic acid is a critical risk factor for acute coronary syndrome in middle-aged older patients as well as younger adult patients. J Cardiol 2014, 63:35-40.
5. Fukuoka Y., Nuruki N., Amiya S., Tofuku K., Aosaki S., Tsubouchi H. Effects of a fish-based diet and administration of pure eicosapentaenoic acid on brachial-ankle pulse wave velocity in patients with cardiovascular risk factors. J Cardiol 2014, 63:211-217.
6. Virmani R., Kolodgie F.D., Burke A.P., Farb A., Schwartz S.M. Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol 2000, 20:1262-1275.
7. Kolodgie F.D., Burke A.P., Farb A., Gold H.K., Yuan J., Narula J., Finn A.V., Virmani R. The thin-cap fibroatheroma: a type of vulnerable plaque: the major precursor lesion to acute coronary syndromes. Curr Opin Cardiol 2001, 16:285-292.
8. Vancraeynest D., Pasquet A., Roelants V., Gerber B.L., Vanoverschelde J.L. Imaging the vulnerable plaque. J Am Coll Cardiol 2011, 57:1961-1979.
9. Glass C.K., Witztum J.L. Atherosclerosis. the road ahead. Cell 2001, 104:503-516.
10. Burke A.P., Tracy R.P., Kolodgie F., Malcom G.T., Zieske A., Kutys R., Pestaner J., Smialek J., Virmani R. Elevated C-reactive protein values and atherosclerosis in sudden coronary death: association with different pathologies. Circulation 2002, 105:2019-2023.
11. Matsuo Y., Kubo T., Okumoto Y., Ishibashi K., Komukai K., Tanimoto T., Ino Y., Kitabata H., Hirata K., Imanishi T., Akagi H., Akasaka T. Circulating malondialdehyde-modified low-density lipoprotein levels are associated with the presence of thin-cap fibroatheromas determined by optical coherence tomography in coronary artery disease. Eur Heart J Cardiovasc Imaging 2013, 14:43-50.
12. Lopez-Garcia E., Schulze M.B., Manson J.E., Meigs J.B., Albert C.M., Rifai N., Willett W.C., Hu F.B. Consumption of (n-3) fatty acids is related to plasma biomarkers of inflammation and endothelial activation in women. J Nutr 2004, 134:1806-1811.
13. Jang I.K., Tearney G.J., MacNeill B., Takano M., Moselewski F., Iftima N., Shishkov M., Houser S., Aretz H.T., Halpern E.F., Bouma B.E. In vivo characterization of coronary atherosclerotic plaque by use of optical coherence tomography. Circulation 2005, 111:1551-1555.
14. Hasegawa T., Otsuka K., Iguchi T., Matsumoto K., Ehara S., Nakata S., Nishimura S., Kataoka T., Shimada K., Yoshiyama M. Serum n-3 to n-6 polyunsaturated fatty acids ratio correlates with coronary plaque vulnerability: an optical coherence tomography study. Heart Vessels 2014, 29:596-602.
15. Thygesen K., Alpert J.S., White H.D. Joint ESC/ACCF/AHA/WHF Task Force for the Redefinition of Myocardial Infarction. Universal definition of myocardial infarction. J Am Coll Cardiol 2007, 50:2173-2195.
16. Tearney G.J., Regar E., Akasaka T., Adriaenssens T., Barlis P., Bezerra H.G., Bouma B., Bruining N., Cho J.M., Chowdhary S., Costa M.A., de Silva R., Dijkstra J., Di Mario C., Dudek D., et al. Consensus standards for acquisition, measurement, and reporting of intravascular optical coherence tomography studies: a report from the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation. J Am Coll Cardiol 2012, 59:1058-1072.
17. Seneviratne A., Hulsmans M., Holvoet P., Monaco C. Biomechanical factors and macrophages in plaque stability. Cardiovasc Res 2013, 99:284-293.
18. Calder P.C. The role of marine omega-3 (n-3) fatty acids in inflammatory processes, atherosclerosis and plaque stability. Mol Nutr Food Res 2012, 56:1073-1080.
19. Itoh M., Suganami T., Satoh N., Tanimoto-Koyama K., Yuan X., Tanaka M., Kawano H., Yano T., Aoe S., Takeya M., Shimatsu A., Kuzuya H., Kamei Y., Ogawa Y. Increased adiponectin secretion by highly purified eicosapentaenoic acid in rodent models of obesity and human obese subjects. Arterioscler Thromb Vasc Biol 2007, 27:1918-1925.
20. Satoh-Asahara N., Shimatsu A., Sasaki Y., Nakaoka H., Himeno A., Tochiya M., Kono S., Takaya T., Ono K., Wada H., Suganami T., Hasegawa K., Ogawa Y. Highly purified eicosapentaenoic acid increases interleukin-10 levels of peripheral blood monocytes in obese patients with dyslipidemia. Diabetes Care 2012, 35:2631-2639.
21. Yamada H., Yoshida M., Nakano Y., Suganami T., Satoh N., Mita T., Azuma K., Itoh M., Yamamoto Y., Kamei Y., Horie M., Watada H., Ogawa Y. In vivo and in vitro inhibition of monocyte adhesion to endothelial cells and endothelial adhesion molecules by eicosapentaenoic acid. Arterioscler Thromb Vasc Biol 2008, 28:2173-2179.
22. Nishio R., Shinke T., Otake H., Nakagawa M., Nagoshi R., Inoue T., Kozuki A., Hariki H., Osue T., Taniguchi Y., Iwasaki M., Hiranuma N., Konishi A., Kinutani H., Shite J., et al. Stabilizing effect of combined eicosapentaenoic acid and statin therapy on coronary thin-cap fibroatheroma. Atherosclerosis 2014, 234:114-119.
23. Koga S., Ikeda S., Yoshida T., Nakata T., Takeno M., Masuda N., Koide Y., Kawano H., Maemura K. Elevated levels of systemic pentraxin 3 are associated with thin-cap fibroatheroma in coronary culprit lesions: assessment by optical coherence tomography and intravascular ultrasound. JACC Cardiovasc Interv 2013, 6:945-954.
24. Nozue T., Yamamoto S., Tohyama S., Fukui K., Umezawa S., Onishi Y., Kunishima T., Sato A., Nozato T., Miyake S., Takeyama Y., Morino Y., Yamauchi T., Muramatsu T., Hibi K., et al. Effects of serum n-3 to n-6 polyunsaturated fatty acids ratios on coronary atherosclerosis in statin-treated patients with coronary artery disease. Am J Cardiol 2013, 111:6-11.
25. Cawood A.L., Ding R., Napper F.L., Young R.H., Williams J.A., Ward M.J., Gudmundsen O., Vige R., Payne S.P., Ye S., Shearman C.P., Gallagher P.J., Grimble R.F., Calder P.C. Eicosapentaenoic acid (EPA) from highly concentrated n-3 fatty acid ethyl esters is incorporated into advanced atherosclerotic plaques and higher plaque EPA is associated with decreased plaque inflammation and increased stability. Atherosclerosis 2010, 212:252-259.
26. Tanaka A., Shimada K., Sano T., Namba M., Sakamoto T., Nishida Y., Kawarabayashi T., Fukuda D., Yoshikawa J. Multiple plaque rupture and C-reactive protein in acute myocardial infarction. J Am Coll Cardiol 2005, 45:1594-1599.
27. Bouki K.P., Katsafados M.G., Chatzopoulos D.N., Psychari S.N., Toutouzas K.P., Charalampopoulos A.F., Sakkali E.N., Koudouri A.A., Liakos G.K., Apostolou T.S. Inflammatory markers and plaque morphology: an optical coherence tomography study. Int J Cardiol 2012, 154:287-292.