Salidroside Mitigates Sepsis-Induced Myocarditis in Rats by Regulating IGF-1/PI3K/Akt/GSK-3β Signaling

Inflammation

Volumn 38, Issue 6, 2015, Pages 2178-2184

  He, He ^a   Chang, Xiayun ^a   Gao, Jin ^a   Zhu, Lingpeng ^a   Miao, Mingxing ^a   Yan, Tianhua ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

IGF I PI3K Akt GSK 3 signaling; myocardial inflammation; salidroside; sepsis

Indexed keywords

CREATINE KINASE; GLYCOGEN SYNTHASE KINASE 3BETA; INTERLEUKIN 1BETA; INTERLEUKIN 6; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SALIDROSIDE; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; AUTACOID; CYTOKINE; GLUCOSIDE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; INSULIN-LIKE GROWTH FACTOR-1, RAT; LIPOPOLYSACCHARIDE, E COLI O55-B5; PHENOL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; HEART MUSCLE CELL; HEART MUSCLE INJURY; HEART PROTECTION; INFLAMMATORY CELL; MALE; MYOCARDITIS; NONHUMAN; PROTEIN EXPRESSION; RAT; SEPSIS; SEPSIS INDUCED MYOCARDIAL INJURY; ANIMAL; BLOOD; CARDIAC MUSCLE; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CYTOKINES; DISEASE MODELS, ANIMAL; GLUCOSIDES; GLYCOGEN SYNTHASE KINASE 3; INFLAMMATION MEDIATORS; INSULIN-LIKE GROWTH FACTOR I; LIPOPOLYSACCHARIDES; MALE; MYOCARDITIS; MYOCARDIUM; PHENOLS; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS, SPRAGUE-DAWLEY; SEPSIS; SIGNAL TRANSDUCTION;

EID: 84946474028     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-015-0200-7     Document Type: Article

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