Mutation of Rv2887, a marR-Like gene, confers mycobacterium tuberculosis resistance to an imidazopyridine-based agent

Antimicrobial Agents and Chemotherapy

Volumn 59, Issue 11, 2015, Pages 6873-6881

  Winglee, Kathryn ^a   Lun, Shichun ^a   Pieroni, Marco ^b   Kozikowski, Alan ^c   Bishai, William ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PARMA   (Italy)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL PROTEIN; BENZOQUINONE; CHLORPROMAZINE; ETHAMBUTOL; IMIDAZOPYRIDINE DERIVATIVE; IMIDAZO[ 1,2 A]PYRIDINE 4 CARBONITRILE; ISONIAZID; MENAQUINONE; MULTIPLE ANTIBIOTIC RESISTANCE REPRESSOR PROTEIN; REPRESSOR PROTEIN; RIFAMPICIN; RNA; RV2887 PROTEIN; TRANSCRIPTOME; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; VERAPAMIL;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM MUTANT; BIOSYNTHESIS; CONTROLLED STUDY; CROSS RESISTANCE; ESCHERICHIA COLI; GENE EXPRESSION; GENE FUNCTION; GENETIC COMPLEMENTATION; LOSS OF FUNCTION MUTATION; MULTIDRUG RESISTANCE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; RNA SEQUENCE; SEQUENCE HOMOLOGY; CHEMISTRY; DRUG EFFECTS; GENETICS; METABOLISM; MICROBIAL SENSITIVITY TEST;

ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ISONIAZID; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS;

EID: 84946213144     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01341-15     Document Type: Article

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