Activity guided isolation and modification of juglone from Juglans regia as potent cytotoxic agent against lung cancer cell lines

BMC Complementary and Alternative Medicine

Volumn 15, Issue 1, 2015, Pages

  Zhang, Xue Bang ^a   Zou, Chang Lin ^a   Duan, Yu Xia ^a   Wu, Fang ^a   Li, Gang ^a  

^a THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

5 [(1 PHENYL 1H 1,2,3 TRIAZOL 4 YL)METHOXY]JUGLONE; 5 [(2 CHLOROPHENYL 1H 1,2,3 TRIAZOL 4 YL)METHOXY]JUGLONE; 5 [[1 (2 BROMOPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHOXY]JUGLONE; 5 [[1 (2 CYANOPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHOXY]JUGLONE; 5 [[1 (2 METHOXYPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHOXY]JUGLONE; 5 [[1 (2 NITROPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHOXY]JUGLONE; 5 [[1 (3 BROMOPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHOXY]JUGLONE; 5 [[1 (3 CYANOPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHOXY]JUGLONE; 5 [[1 (3 METHOXYPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHOXY]JUGLONE; 5 [[1 (3 NITROPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHOXY]JUGLONE; 5 [[1 (4 CYANOPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHOXY]JUGLONE; 5 [[1 (4 METHOXYPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHOXY]JUGLONE; 5 [[1 (4 NITROPHENYL) 1H 1,2,3 TRIAZOL 4 YL]METHOXY]JUGLONE; ANTINEOPLASTIC AGENT; DACTOLISIB; JUGLANS REGIA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG; JUGLONE; NAPHTHOQUINONE;

A549 CELL LINE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL MEDIATED CYTOTOXICITY; CHROMATOGRAPHY; CONTROLLED STUDY; DRUG DETERMINATION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC50; JUGLANS REGIA; LUNG CANCER CELL LINE; MTT ASSAY; NCI H322 CELL LINE; PHYTOCHEMISTRY; PLANT ROOT; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; ISOLATION AND PURIFICATION; LUNG NEOPLASMS; PATHOPHYSIOLOGY; TUMOR CELL LINE; WALNUT;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; JUGLANS; LUNG NEOPLASMS; NAPHTHOQUINONES; PLANT EXTRACTS;

EID: 84946069746     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/s12906-015-0920-0     Document Type: Article

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