Cigarette side-stream smoke lung and bladder carcinogenesis: Inducing mutagenic acrolein-DNA adducts, inhibiting DNA repair and enhancing anchorage-independent-growth cell transformation

Oncotarget

Volumn 6, Issue 32, 2015, Pages 33226-33236

  Lee, Hyun Wook ^a   Wang, Hsiang Tsui ^a   Weng, Mao Wen ^a   Chin, Chiu ^a   Huang, William ^a   Lepor, Herbert ^a   Wu, Xue Ru ^a   Rom, William N ^a   Chen, Lung Chi ^a   Tang, Moon Shong ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acrolein and BPDE; Anchorage independent growth; DNA damage and repair; Lung and bladder cancer; Second hand and side stream smoke

Indexed keywords

ACROLEIN; BENZO(A)PYRENE DIOL EPOXIDE; CIGARETTE SIDE STREAM SMOKE; CIGARETTE SMOKE; CYCLIC PROPANO DEOXYGUANOSINE; DNA; MEMBRANE PROTEIN; POLYCYCLIC AROMATIC HYDROCARBON; PROTEIN HOGG1; UNCLASSIFIED DRUG; XERODERMA PIGMENTOSUM GROUP C PROTEIN; DNA ADDUCT; SMOKE;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BLADDER; BLADDER CANCER; BRONCHUS MUCOSA; CELL TRANSFORMATION; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DNA REPAIR; EPITHELIUM CELL; EXCISION REPAIR; HEART; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER; LUNG; LUNG CANCER; LUNG LAVAGE; MALE; MOUSE; NONHUMAN; PROTEIN DEGRADATION; SMOKING; UROTHELIUM; ADVERSE EFFECTS; ANIMAL; BLADDER TUMOR; CARCINOGENESIS; CELL ADHESION; CELL PROLIFERATION; DRUG EFFECTS; GENETICS; LUNG NEOPLASMS; METABOLISM; PATHOLOGY; SMOKE; TOBACCO;

ACROLEIN; ANIMALS; CARCINOGENESIS; CELL ADHESION; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; DNA ADDUCTS; DNA REPAIR; LUNG NEOPLASMS; MALE; MICE; SMOKE; TOBACCO PRODUCTS; URINARY BLADDER NEOPLASMS;

EID: 84946040631     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5429     Document Type: Article

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