Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer

Nature

Volumn 526, Issue 7575, 2015, Pages 723-727

  Wei, Jia ^a   Tong, Liang ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; BIOTIN; BIOTIN CARBOXYLASE; CARBOXYLASE; HOLOENZYME; NATURAL PRODUCT; SORAPHEN A; UNCLASSIFIED DRUG; PROTEIN SUBUNIT;

CANCER; CATALYSIS; CRYSTAL STRUCTURE; DIABETES; ENZYME ACTIVITY; EUKARYOTE; FATTY ACID; HOMOLOGY; INHIBITION; METABOLISM; PROTEIN; YEAST;

ARTICLE; BINDING SITE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; DRUG MECHANISM; ENZYME ACTIVE SITE; GROWTH INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN SECONDARY STRUCTURE; BIOCATALYSIS; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR MODEL; MOLECULAR WEIGHT; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN SUBUNIT; PROTEIN TERTIARY STRUCTURE; SACCHAROMYCES CEREVISIAE; X RAY CRYSTALLOGRAPHY;

EUKARYOTA; MAMMALIA; SACCHAROMYCES CEREVISIAE;

ACETYL-COA CARBOXYLASE; BINDING SITES; BIOCATALYSIS; BIOTIN; CRYSTALLOGRAPHY, X-RAY; HOLOENZYMES; MODELS, MOLECULAR; MOLECULAR WEIGHT; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; SACCHAROMYCES CEREVISIAE;

EID: 84945904400     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature15375     Document Type: Article

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