Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export

Cell Reports

Volumn 13, Issue 4, 2015, Pages 690-702

  Port, Sarah A ^a   Monecke, Thomas ^a   Dickmanns, Achim ^a   Spillner, Christiane ^a   Hofele, Romina ^b,c   Urlaub, Henning ^b,c   Ficner, Ralf ^a   Kehlenbach, Ralph H ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^c UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CLEOPORIN; EXPORTIN 1; GLYCINE; GUANOSINE TRIPHOSPHATASE; KARYOPHERIN; NUCLEAR PROTEIN; NUCLEOPORIN; PHENYLALANINE; PROTEIN NUP214; SNURPORTIN 1; UNCLASSIFIED DRUG; CELL RECEPTOR; EXPORTIN 1 PROTEIN; NUP214 PROTEIN, HUMAN; PROTEIN BINDING;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL ASSAY; COMPARATIVE STUDY; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; GENETIC CONSERVATION; HYDROPHOBICITY; IN VITRO STUDY; MASS SPECTROMETRY; MOLECULAR RECOGNITION; NUCLEAR EXPORT SIGNAL; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY; ACTIVE TRANSPORT; CELL NUCLEUS; CHEMISTRY; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; TRANSPORT AT THE CELLULAR LEVEL;

ACTIVE TRANSPORT, CELL NUCLEUS; BINDING SITES; BIOLOGICAL TRANSPORT; CELL NUCLEUS; CRYSTALLOGRAPHY, X-RAY; HUMANS; KARYOPHERINS; NUCLEAR PORE COMPLEX PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CYTOPLASMIC AND NUCLEAR;

EID: 84945565647     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.09.042     Document Type: Article

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