Genotypic and phenotypic analyses of a Pseudomonas aeruginosa chronic bronchiectasis isolate reveal differences from cystic fibrosis and laboratory strains

BMC Genomics

Volumn 16, Issue 1, 2015, Pages

  Varga, John J ^a,b,c   Barbier, Mariette ^c,d   Mulet, Xavier ^e   Bielecki, Piotr ^f,k   Bartell, Jennifer A ^g   Owings, Joshua P ^a,b,c   Martinez Ramos, Inmaculada ^h   Hittle, Lauren E ⁱ   Davis, Michael R ^c   Damron, F Heath ^c,d   Liechti, George W ^c   Puchałka, Jacek ^e,l   dos Santos, Vitor A P Martins ^j,m   Ernst, Robert K ⁱ   Papin, Jason A ^g   Albertí, Sebastian ^h   Oliver, Antonio ^e   Goldberg, Joanna B ^a,b,c  

^a Section of Pulmonology   (United States)

^b CHILDREN'S HEALTHCARE OF ATLANTA   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e HOSPITAL UNIVERSITARIO SON ESPASES   (Spain)

^f HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^g University of Virginia   (United States)

^h UNIVERSITAT DE LES ILLES BALEARS   (Spain)

ⁱ UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

^j WAGENINGEN UNIVERSITY   (Netherlands)

^k YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^l LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^m LIFEGLIMMER GMBH   (Germany)

more..

Author keywords

Bronchiectasis; Comparative genomics; Cystic fibrosis; Metabolic model; Pseudomonas aeruginosa; Transcriptome

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE AMPC; CARBENICILLIN; CEFOTAXIME; CEFTAZIDIME; CEPHALOSPORIN; CEPHALOSPORIN DERIVATIVE; CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING) B; GENTAMICIN; MACROLIDE; MONOBACTAM DERIVATIVE; PENICILLIN DERIVATIVE; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; POLYMYXIN DERIVATIVE; PROTEIN MUTS; PROTEIN PARC; PROTEIN PARE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TETRACYCLINE; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; TRANSCRIPTOME;

ADAPTATION; AGED; AMINO ACID METABOLISM; AMPC GENE; AMPD GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; BIOFILM; BRONCHIECTASIS; CASE REPORT; CONTROLLED STUDY; CYSTIC FIBROSIS; DACB GENE; DOWN REGULATION; FEMALE; GENE SEQUENCE; GENOME ANALYSIS; GENOTYPE; GYRA GENE; GYRB GENE; HUMAN; HUMAN CELL; LIPID METABOLISM; MEXB GENE; MOUSE; MUTATION RATE; MUTS GENE; NONHUMAN; PARA GENE; PARC GENE; PARE GENE; PHENOTYPE; PHENOTYPIC VARIATION; PROTEIN SECRETION; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; SEQUENCE ANALYSIS; SPECIES DIFFERENCE; STRAIN DIFFERENCE; TRANSCRIPTOMICS; UPREGULATION; WILD TYPE; ALLELE; BIOLOGY; CHRONIC DISEASE; COMPLICATION; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENE ORDER; GENETICS; GENOMICS; HIGH THROUGHPUT SEQUENCING; ISOLATION AND PURIFICATION; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MOLECULAR GENETICS; MUTATION; PATHOGENICITY; PHYSIOLOGY; PSEUDOMONAS INFECTIONS; SECONDARY METABOLISM; VIRULENCE;

ADAPTATION, BIOLOGICAL; ALLELES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BIOFILMS; BRONCHIECTASIS; CHRONIC DISEASE; COMPUTATIONAL BIOLOGY; CYSTIC FIBROSIS; DRUG RESISTANCE, BACTERIAL; GENE EXPRESSION PROFILING; GENE ORDER; GENOME, BACTERIAL; GENOMICS; GENOTYPE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MUTATION; MUTATION RATE; PHENOTYPE; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; QUORUM SENSING; SECONDARY METABOLISM; TRANSCRIPTOME; VIRULENCE;

EID: 84945561988     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-015-2069-0     Document Type: Article

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