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Volumn 65, Issue 9, 1997, Pages 3838-3846

Mucoid Pseudomonas aeruginosa in cystic fibrosis: Characterization of muc mutations in clinical isolates and analysis of clearance in a mouse model of respiratory infection

Author keywords

[No Author keywords available]

Indexed keywords

ALGINIC ACID; BACTERIAL POLYSACCHARIDE; MUCIN; SIGMA FACTOR;

EID: 0030931824     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.9.3838-3846.1997     Document Type: Article
Times cited : (221)

References (46)
  • 1
    • 0019515474 scopus 로고
    • Influence of mucoid coating on clearance of Pseudomonas aeruginosa from lungs
    • Blackwood, L. L., and J. E. Pennington. 1981. Influence of mucoid coating on clearance of Pseudomonas aeruginosa from lungs. Infect. Immun. 32:443-448.
    • (1981) Infect. Immun. , vol.32 , pp. 443-448
    • Blackwood, L.L.1    Pennington, J.E.2
  • 5
    • 0030034915 scopus 로고    scopus 로고
    • Two distinct loci affecting conversion to mucoidy in Pseudomonas aeruginosa in cystic fibrosis encode homologs of the serine protease HtrA
    • Boucher, J. C., J. M. Martinez-Salazar, M. J. Schurr, M. H. Mudd, H. Yu, and V. Deretic. 1996. Two distinct loci affecting conversion to mucoidy in Pseudomonas aeruginosa in cystic fibrosis encode homologs of the serine protease HtrA. J. Bacteriol. 178:511-523.
    • (1996) J. Bacteriol. , vol.178 , pp. 511-523
    • Boucher, J.C.1    Martinez-Salazar, J.M.2    Schurr, M.J.3    Mudd, M.H.4    Yu, H.5    Deretic, V.6
  • 6
    • 0023089190 scopus 로고
    • Gene algD coding for GDPmannose dehydrogenase is transcriptionally activated in mucoid Pseudomonas aeruginosa
    • Deretic, V., J. F. Gill, and A. M. Chakrabarty. 1987. Gene algD coding for GDPmannose dehydrogenase is transcriptionally activated in mucoid Pseudomonas aeruginosa. J. Bacteriol. 169:351-358.
    • (1987) J. Bacteriol. , vol.169 , pp. 351-358
    • Deretic, V.1    Gill, J.F.2    Chakrabarty, A.M.3
  • 7
    • 0028046468 scopus 로고
    • Mucoid-to-nonmucoid conversion in alginate-producing Pseudomonas aeruginosa often results from spontaneous mutations in algT, encoding a putative alternate sigma factor, and shows evidence for autoregulation
    • DeVries, C. A., and D. E. Ohman. 1994. Mucoid-to-nonmucoid conversion in alginate-producing Pseudomonas aeruginosa often results from spontaneous mutations in algT, encoding a putative alternate sigma factor, and shows evidence for autoregulation. J. Bacteriol. 176:6677-6687.
    • (1994) J. Bacteriol. , vol.176 , pp. 6677-6687
    • Devries, C.A.1    Ohman, D.E.2
  • 8
    • 0015244903 scopus 로고
    • Mucoid Pseudomonas aeruginosa in patients with chronic illnesses
    • Doggett, G., G. M. Harrison, and R. E. Carter. 1971. Mucoid Pseudomonas aeruginosa in patients with chronic illnesses. Lancet i:236-237.
    • (1971) Lancet , vol.1 , pp. 236-237
    • Doggett, G.1    Harrison, G.M.2    Carter, R.E.3
  • 9
    • 0028029258 scopus 로고
    • The rbf locus from Pseudomonas aeruginosa strain PA103 promotes the expression of O antigen by both LPS-rough and LPS-smooth isolates from cystic fibrosis patients
    • Evans, D. J., G. B. Pier, M. J. Coyne, Jr., and J. B. Goldberg. 1994. The rbf locus from Pseudomonas aeruginosa strain PA103 promotes the expression of O antigen by both LPS-rough and LPS-smooth isolates from cystic fibrosis patients. Mol. Microbiol. 13:427-434.
    • (1994) Mol. Microbiol. , vol.13 , pp. 427-434
    • Evans, D.J.1    Pier, G.B.2    Coyne Jr., M.J.3    Goldberg, J.B.4
  • 10
    • 0023885755 scopus 로고
    • Cloning of genes from mucoid Pseudomonas aeruginosa which control spontaneous conversion to the alginate production phenotype
    • Flynn, J. L., and D. E. Ohman. 1988. Cloning of genes from mucoid Pseudomonas aeruginosa which control spontaneous conversion to the alginate production phenotype. J. Bacteriol. 170:1452-1460.
    • (1988) J. Bacteriol. , vol.170 , pp. 1452-1460
    • Flynn, J.L.1    Ohman, D.E.2
  • 11
    • 0020981520 scopus 로고
    • Synthesis, regulation and biological function of bacterial alginate
    • Fyfe, J. A. M., and J. R. W. Govan. 1983. Synthesis, regulation and biological function of bacterial alginate. Prog. Ind. Microbiol. 18:45-83.
    • (1983) Prog. Ind. Microbiol. , vol.18 , pp. 45-83
    • Fyfe, J.A.M.1    Govan, J.R.W.2
  • 12
    • 0019136294 scopus 로고
    • Alginate synthesis in mucoid Pseudomonas aeruginosa: A chromosomal locus involved in control
    • Fyfe, J. A. M., and J. R. W. Govan. 1980. Alginate synthesis in mucoid Pseudomonas aeruginosa: a chromosomal locus involved in control. J. Gen. Microbiol. 119:443-450.
    • (1980) J. Gen. Microbiol. , vol.119 , pp. 443-450
    • Fyfe, J.A.M.1    Govan, J.R.W.2
  • 13
    • 0030949875 scopus 로고    scopus 로고
    • Human β-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis
    • Goldman, M. J., G. M. Anderson, E. D. Stolzenberg, L. P. Kari, M. Zasloff, and J. M. Wilson. 1997. Human β-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis. Cell 88:553-560.
    • (1997) Cell , vol.88 , pp. 553-560
    • Goldman, M.J.1    Anderson, G.M.2    Stolzenberg, E.D.3    Kari, L.P.4    Zasloff, M.5    Wilson, J.M.6
  • 14
    • 0029814366 scopus 로고    scopus 로고
    • Microbial pathogenesis in cystic fibrosis: Mucoid Pseudomonas aeruginosa and Burkholderia cepacia
    • Govan, J. R. W., and V. Deretic. 1996. Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia. Microbiol. Rev. 60:539-574.
    • (1996) Microbiol. Rev. , vol.60 , pp. 539-574
    • Govan, J.R.W.1    Deretic, V.2
  • 16
    • 0342561247 scopus 로고
    • Formation of pilin in Pseudomonas aeruginosa requires the alternative sigma factor (rpoN) of RNA polymerase
    • Ishimoto, K. S., and S. Lory. 1989. Formation of pilin in Pseudomonas aeruginosa requires the alternative sigma factor (rpoN) of RNA polymerase. Proc. Natl. Acad. Sci. USA 86:1954-1957.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 1954-1957
    • Ishimoto, K.S.1    Lory, S.2
  • 17
    • 0026021682 scopus 로고
    • Phase variation of gonococcal pili by frameshift mutation in pilC, a novel gene for pilus assembly
    • Jonsson, A. B., G. Nyberg, and S. Normark. 1991. Phase variation of gonococcal pili by frameshift mutation in pilC, a novel gene for pilus assembly. EMBO J. 10:477-488.
    • (1991) EMBO J. , vol.10 , pp. 477-488
    • Jonsson, A.B.1    Nyberg, G.2    Normark, S.3
  • 19
    • 0014330073 scopus 로고
    • A new modification of the carbazole reaction: Application to heteropolysaccharides
    • Knutson, C. A., and A. Jeanes. 1976. A new modification of the carbazole reaction: application to heteropolysaccharides. Anal. Biochem. 24:470-481.
    • (1976) Anal. Biochem. , vol.24 , pp. 470-481
    • Knutson, C.A.1    Jeanes, A.2
  • 20
    • 0027404779 scopus 로고
    • Pathogenesis of cystic fibrosis
    • Koch, C., and N. Hoiby. 1993. Pathogenesis of cystic fibrosis. Lancet 341: 1065-1069.
    • (1993) Lancet , vol.341 , pp. 1065-1069
    • Koch, C.1    Hoiby, N.2
  • 21
    • 0018896292 scopus 로고
    • Production of mucoid microcolonies by Pseudomonas aeruginosa within infected lungs in cystic fibrosis
    • Lam, J., R. Chan, K. Lam, and J. W. Costerton. 1980. Production of mucoid microcolonies by Pseudomonas aeruginosa within infected lungs in cystic fibrosis. Infect. Immun. 28:546-556.
    • (1980) Infect. Immun. , vol.28 , pp. 546-556
    • Lam, J.1    Chan, R.2    Lam, K.3    Costerton, J.W.4
  • 22
    • 0023389741 scopus 로고
    • Hypochlorite scavenging by Pseudomonas aeruginosa alginate
    • Learn, D. B., E. P. Brestel, and S. Seetharama. 1987. Hypochlorite scavenging by Pseudomonas aeruginosa alginate. Infect. Immun. 55:1813-1818.
    • (1987) Infect. Immun. , vol.55 , pp. 1813-1818
    • Learn, D.B.1    Brestel, E.P.2    Seetharama, S.3
  • 23
    • 0027399389 scopus 로고
    • Characterization of a locus determining the mucoid status of Pseudomonas aeruginosa: AlgU shows sequence similarities with a Bacillus sigma factor
    • Martin, D. W., B. W. Holloway, and V. Deretic. 1993. Characterization of a locus determining the mucoid status of Pseudomonas aeruginosa: AlgU shows sequence similarities with a Bacillus sigma factor. J. Bacteriol. 175: 1153-1164.
    • (1993) J. Bacteriol. , vol.175 , pp. 1153-1164
    • Martin, D.W.1    Holloway, B.W.2    Deretic, V.3
  • 24
    • 0027316962 scopus 로고
    • Differentiation of Pseudomonas aeruginosa into the alginate-producing form: Inactivation of mucB causes conversion to mucoidy
    • Martin, D. W., M. J. Schurr, M. H. Mudd, and V. Deretic. 1993. Differentiation of Pseudomonas aeruginosa into the alginate-producing form: inactivation of mucB causes conversion to mucoidy. Mol. Microbiol. 9:497-506.
    • (1993) Mol. Microbiol. , vol.9 , pp. 497-506
    • Martin, D.W.1    Schurr, M.J.2    Mudd, M.H.3    Deretic, V.4
  • 26
    • 0024603888 scopus 로고
    • Isolation of mucoid strains of Pseudomonas aeruginosa from non-cystic fibrosis patients and characterization of the structure of their secreted alginate
    • McAvoy, M. J., V. Newton, A. Paull, J. Morgan, P. Gacesa, and N. J. Russell. 1989. Isolation of mucoid strains of Pseudomonas aeruginosa from non-cystic fibrosis patients and characterization of the structure of their secreted alginate. J. Med. Microbiol. 28:183-189.
    • (1989) J. Med. Microbiol. , vol.28 , pp. 183-189
    • McAvoy, M.J.1    Newton, V.2    Paull, A.3    Morgan, J.4    Gacesa, P.5    Russell, N.J.6
  • 27
    • 0025009266 scopus 로고
    • Gene-scrambling mutagenesis: Generation and analysis of insertional mutations in the alginate regulatory region of Pseudomonas aeruginosa
    • Mohr, C. D., and V. Deretic. 1990. Gene-scrambling mutagenesis: generation and analysis of insertional mutations in the alginate regulatory region of Pseudomonas aeruginosa. J. Bacteriol. 172:6252-6260.
    • (1990) J. Bacteriol. , vol.172 , pp. 6252-6260
    • Mohr, C.D.1    Deretic, V.2
  • 28
    • 0028940850 scopus 로고
    • Endobronchial inflammation following Pseudomonas aeruginosa infection in resistant and susceptible strains of mice
    • Morissette, C., E. Skamene, and F. Gervais. 1995. Endobronchial inflammation following Pseudomonas aeruginosa infection in resistant and susceptible strains of mice. Infect. Immun. 63:1718-1724.
    • (1995) Infect. Immun. , vol.63 , pp. 1718-1724
    • Morissette, C.1    Skamene, E.2    Gervais, F.3
  • 29
    • 0029807127 scopus 로고    scopus 로고
    • Lung phagocyte bactericidal function in strains of mice resistant and susceptible to Pseudomonas aeruginosa
    • Morissette, C., C. Francoeur, C. Darmond-Zwaig, and F. Gervais. 1996. Lung phagocyte bactericidal function in strains of mice resistant and susceptible to Pseudomonas aeruginosa. Infect. Immun. 64:4984-4992.
    • (1996) Infect. Immun. , vol.64 , pp. 4984-4992
    • Morissette, C.1    Francoeur, C.2    Darmond-Zwaig, C.3    Gervais, F.4
  • 30
    • 0026492517 scopus 로고
    • Lung infection with alginate-producing, mucoid Pseudomonas aeruginosa in cystic fibrosis
    • Pedersen, S. S. 1992. Lung infection with alginate-producing, mucoid Pseudomonas aeruginosa in cystic fibrosis. APMIS 100(Suppl. 28):1-79.
    • (1992) APMIS , vol.100 , Issue.28 SUPPL. , pp. 1-79
    • Pedersen, S.S.1
  • 32
    • 0019986441 scopus 로고
    • Phenotypic differences among clinically isolated mucoid Pseudomonas aeruginosa strains
    • Pugashetti, B. K., H. M. Metzger, Jr., L. Vadas, and D. S. Feingold. 1982. Phenotypic differences among clinically isolated mucoid Pseudomonas aeruginosa strains. J. Clin. Microbiol. 16:686-691.
    • (1982) J. Clin. Microbiol. , vol.16 , pp. 686-691
    • Pugashetti, B.K.1    Metzger Jr., H.M.2    Vadas, L.3    Feingold, D.S.4
  • 33
    • 0030956112 scopus 로고    scopus 로고
    • Microbial pathogenesis in cystic fibrosis: Coordinate regulation of heat shock response and conversion to mucoidy in Pseudomonas aeruginosa
    • Schurr, M. J., and V. Deretic. 1997. Microbial pathogenesis in cystic fibrosis: coordinate regulation of heat shock response and conversion to mucoidy in Pseudomonas aeruginosa. Mol. Microbiol. 24:411-420.
    • (1997) Mol. Microbiol. , vol.24 , pp. 411-420
    • Schurr, M.J.1    Deretic, V.2
  • 34
    • 0028238979 scopus 로고
    • Gene cluster controlling conversion to alginate-overproducing phenotype in Pseudomonas aeruginosa: Functional analysis in a heterologous host and role in the instability of mucoidy
    • Schurr, M. J., D. W. Martin, M. H. Mudd, and V. Deretic. 1994. Gene cluster controlling conversion to alginate-overproducing phenotype in Pseudomonas aeruginosa: functional analysis in a heterologous host and role in the instability of mucoidy. J. Bacteriol. 176:3375-3382.
    • (1994) J. Bacteriol. , vol.176 , pp. 3375-3382
    • Schurr, M.J.1    Martin, D.W.2    Mudd, M.H.3    Deretic, V.4
  • 35
    • 0029747226 scopus 로고    scopus 로고
    • E-like family of stress sigma factors, by the negative regulators Muca and MucB and Pseudomonas aeruginosa conversion to mucoidy in cystic fibrosis
    • E-like family of stress sigma factors, by the negative regulators MucA and MucB and Pseudomonas aeruginosa conversion to mucoidy in cystic fibrosis. J. Bacteriol. 178:4997-5004.
    • (1996) J. Bacteriol. , vol.178 , pp. 4997-5004
    • Schurr, M.J.1    Yu, H.2    Martinez-Salazar, J.M.3    Boucher, J.C.4    Deretic, V.5
  • 36
    • 0001564471 scopus 로고
    • Antiphagocytic effect of slime from a mucoid strain of Pseudomonas aeruginosa
    • Schwarzmann, S., and J. R. Boring III. 1971. Antiphagocytic effect of slime from a mucoid strain of Pseudomonas aeruginosa. Infect. Immun. 3:762-767.
    • (1971) Infect. Immun. , vol.3 , pp. 762-767
    • Schwarzmann, S.1    Boring III, J.R.2
  • 37
    • 0024556654 scopus 로고
    • Scavenging by alginate of free radicals released by macrophages
    • Simpson, J. A., S. E. Smith, and R. T. Dean. 1989. Scavenging by alginate of free radicals released by macrophages. Free Radical Biol. Med. 6:347-353.
    • (1989) Free Radical Biol. Med. , vol.6 , pp. 347-353
    • Simpson, J.A.1    Smith, S.E.2    Dean, R.T.3
  • 38
    • 0029870085 scopus 로고    scopus 로고
    • Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid
    • Smith, J. J., S. M. Travis, E. P. Greenberg, and M. J. Welsh. 1996. Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid. Cell 85:1-20.
    • (1996) Cell , vol.85 , pp. 1-20
    • Smith, J.J.1    Travis, S.M.2    Greenberg, E.P.3    Welsh, M.J.4
  • 39
    • 0001884014 scopus 로고
    • Pseudomonas aeruginosa infections in patients with cystic fibrosis
    • A. L. Baltch and R. P. Smith (ed.), Marcel Dekker, Inc., New York, N.Y.
    • Speert, D. P. 1994. Pseudomonas aeruginosa infections in patients with cystic fibrosis, p. 183-236. In A. L. Baltch and R. P. Smith (ed.), Pseudomonas aeruginosa infections and treatment. Marcel Dekker, Inc., New York, N.Y.
    • (1994) Pseudomonas Aeruginosa Infections and Treatment , pp. 183-236
    • Speert, D.P.1
  • 40
    • 0018717164 scopus 로고
    • The relationship of inoculum size to lung bacterial clearance and phagocytic cell response in mice
    • Toews, G. B., G. N. Gross, and A. K. Pierce. 1979. The relationship of inoculum size to lung bacterial clearance and phagocytic cell response in mice. Am. Rev. Respir. Dis. 120:559-566.
    • (1979) Am. Rev. Respir. Dis. , vol.120 , pp. 559-566
    • Toews, G.B.1    Gross, G.N.2    Pierce, A.K.3
  • 41
  • 42
    • 0031027284 scopus 로고    scopus 로고
    • Identification of the algZ gene upstream of the response regulator algR and its participation in control of alginate production in Pseudomonas aeruginosa
    • Yu, H., M. Mudd, J. C. Boucher, M. J. Schurr, and V. Deretic. 1997. Identification of the algZ gene upstream of the response regulator algR and its participation in control of alginate production in Pseudomonas aeruginosa. J. Bacteriol. 179:187-193.
    • (1997) J. Bacteriol. , vol.179 , pp. 187-193
    • Yu, H.1    Mudd, M.2    Boucher, J.C.3    Schurr, M.J.4    Deretic, V.5
  • 44
    • 9844254121 scopus 로고    scopus 로고
    • Molecular mechanism of conversion to mucoidy in Pseudomonas aeruginosa
    • S. Silver, T. Nakazowa, and D. Haas (ed.), in press. ASM Press, Washington, D.C.
    • Yu, H., M. J. Schurr, J. C. Boucher, J. M. Martinez-Salazar, D. W. Martin, and V. Deretic. Molecular mechanism of conversion to mucoidy in Pseudomonas aeruginosa. In S. Silver, T. Nakazowa, and D. Haas (ed.), Pseudomonas, in press. ASM Press, Washington, D.C.
    • Pseudomonas
    • Yu, H.1    Schurr, M.J.2    Boucher, J.C.3    Martinez-Salazar, J.M.4    Martin, D.W.5    Deretic, V.6
  • 45
    • 0029073143 scopus 로고
    • E and Pseudomonas aeruginosa AlgU: E. coli rpoE restores mucoidy and reduces sensitivity to reactive oxygen intermediates in algU mutants of P. aeruginosa
    • E and Pseudomonas aeruginosa AlgU: E. coli rpoE restores mucoidy and reduces sensitivity to reactive oxygen intermediates in algU mutants of P. aeruginosa. J. Bacteriol. 177:3259-3268.
    • (1995) J. Bacteriol. , vol.177 , pp. 3259-3268
    • Yu, H.1    Schurr, M.J.2    Deretic, V.3
  • 46
    • 0028847778 scopus 로고
    • Binding of Pseudomonas aeruginosa to respiratory epithelial cells from patient with various mutations in the cystic fibrosis transmembrane regulator
    • Zar, H., L. Saiman, L. Quittell, and A. Prince. 1995. Binding of Pseudomonas aeruginosa to respiratory epithelial cells from patient with various mutations in the cystic fibrosis transmembrane regulator. J. Pediatr. 126:230-233.
    • (1995) J. Pediatr. , vol.126 , pp. 230-233
    • Zar, H.1    Saiman, L.2    Quittell, L.3    Prince, A.4


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