메뉴 건너뛰기




Volumn 16, Issue 1, 2015, Pages

Prior infection with Type A Francisella tularensis antagonizes the pulmonary transcriptional response to an aerosolized Toll-like receptor 4 agonist

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; FORKHEAD TRANSCRIPTION FACTOR; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; HEPATOCYTE NUCLEAR FACTOR 3BETA; INTERFERON REGULATORY FACTOR 1; MYOCYTE ENHANCER FACTOR 2; TOLL LIKE RECEPTOR 4; AEROSOL; LIPOPOLYSACCHARIDE;

EID: 84945530588     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-015-2022-2     Document Type: Article
Times cited : (13)

References (63)
  • 1
    • 75449130590 scopus 로고
    • Tularemia: a perusal of three hundred thirty-nine cases
    • Dienst Jr FT. Tularemia: a perusal of three hundred thirty-nine cases. J La State Med Soc. 1963;115:114-27.
    • (1963) J La State Med Soc , vol.115 , pp. 114-127
    • Dienst, F.T.1
  • 3
    • 33947702199 scopus 로고    scopus 로고
    • Active suppression of the pulmonary immune response by Francisella tularensis Schu4
    • Bosio CM, Bielefeldt-Ohmann H, Belisle JT. Active suppression of the pulmonary immune response by Francisella tularensis Schu4. J Immunol. 2007;178(7):4538-47.
    • (2007) J Immunol , vol.178 , Issue.7 , pp. 4538-4547
    • Bosio, C.M.1    Bielefeldt-Ohmann, H.2    Belisle, J.T.3
  • 4
    • 44749083060 scopus 로고    scopus 로고
    • Francisella gains a survival advantage within mononuclear phagocytes by suppressing the host IFNgamma response
    • Parsa KV, Butchar JP, Rajaram MV, Cremer TJ, Gunn JS, Schlesinger LS, et al. Francisella gains a survival advantage within mononuclear phagocytes by suppressing the host IFNgamma response. Mol Immunol. 2008;45(12):3428-37.
    • (2008) Mol Immunol , vol.45 , Issue.12 , pp. 3428-3437
    • Parsa, K.V.1    Butchar, J.P.2    Rajaram, M.V.3    Cremer, T.J.4    Gunn, J.S.5    Schlesinger, L.S.6
  • 5
    • 27744547036 scopus 로고    scopus 로고
    • Francisella tularensis induces aberrant activation of pulmonary dendritic cells
    • Bosio CM, Dow SW. Francisella tularensis induces aberrant activation of pulmonary dendritic cells. J Immunol. 2005;175(10):6792-801.
    • (2005) J Immunol , vol.175 , Issue.10 , pp. 6792-6801
    • Bosio, C.M.1    Dow, S.W.2
  • 6
    • 58449133177 scopus 로고    scopus 로고
    • Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4
    • Chase JC, Celli J, Bosio CM. Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4. Infect Immun. 2009;77(1):180-95.
    • (2009) Infect Immun , vol.77 , Issue.1 , pp. 180-195
    • Chase, J.C.1    Celli, J.2    Bosio, C.M.3
  • 7
    • 77956257884 scopus 로고    scopus 로고
    • Francisella tularensis antioxidants harness reactive oxygen species to restrict macrophage signaling and cytokine production
    • Melillo AA, Bakshi CS, Melendez JA. Francisella tularensis antioxidants harness reactive oxygen species to restrict macrophage signaling and cytokine production. J Biol Chem. 2010;285(36):27553-60.
    • (2010) J Biol Chem , vol.285 , Issue.36 , pp. 27553-27560
    • Melillo, A.A.1    Bakshi, C.S.2    Melendez, J.A.3
  • 8
    • 84882416296 scopus 로고    scopus 로고
    • Repression of inflammasome by Francisella tularensis during early stages of infection
    • Dotson RJ, Rabadi SM, Westcott EL, Bradley S, Catlett SV, Banik S, et al. Repression of inflammasome by Francisella tularensis during early stages of infection. J Biol Chem. 2013;288(33):23844-57.
    • (2013) J Biol Chem , vol.288 , Issue.33 , pp. 23844-23857
    • Dotson, R.J.1    Rabadi, S.M.2    Westcott, E.L.3    Bradley, S.4    Catlett, S.V.5    Banik, S.6
  • 9
    • 84864094243 scopus 로고    scopus 로고
    • Identification of a novel Francisella tularensis factor required for intramacrophage survival and subversion of innate immune response
    • Mahawar M, Atianand MK, Dotson RJ, Mora V, Rabadi SM, Metzger DW, et al. Identification of a novel Francisella tularensis factor required for intramacrophage survival and subversion of innate immune response. J Biol Chem. 2012;287(30):25216-29.
    • (2012) J Biol Chem , vol.287 , Issue.30 , pp. 25216-25229
    • Mahawar, M.1    Atianand, M.K.2    Dotson, R.J.3    Mora, V.4    Rabadi, S.M.5    Metzger, D.W.6
  • 10
    • 84880662681 scopus 로고    scopus 로고
    • Francisella tularensis SchuS4 and SchuS4 lipids inhibit IL-12p40 in primary human dendritic cells by inhibition of IRF1 and IRF8
    • Ireland R, Wang R, Alinger JB, Small P, Bosio CM. Francisella tularensis SchuS4 and SchuS4 lipids inhibit IL-12p40 in primary human dendritic cells by inhibition of IRF1 and IRF8. J Immunol. 2013;191(3):1276-86.
    • (2013) J Immunol , vol.191 , Issue.3 , pp. 1276-1286
    • Ireland, R.1    Wang, R.2    Alinger, J.B.3    Small, P.4    Bosio, C.M.5
  • 11
    • 34748872662 scopus 로고    scopus 로고
    • Molecular and genetic basis of pathogenesis in Francisella tularensis
    • Barker JR, Klose KE. Molecular and genetic basis of pathogenesis in Francisella tularensis. Ann N Y Acad Sci. 2007;1105:138-59.
    • (2007) Ann N Y Acad Sci , vol.1105 , pp. 138-159
    • Barker, J.R.1    Klose, K.E.2
  • 12
    • 77952691205 scopus 로고    scopus 로고
    • Francisella tularensis DeltapyrF mutants show that replication in nonmacrophages is sufficient for pathogenesis in vivo
    • Horzempa J, O'Dee DM, Shanks RM, Nau GJ. Francisella tularensis DeltapyrF mutants show that replication in nonmacrophages is sufficient for pathogenesis in vivo. Infect Immun. 2010;78(6):2607-19.
    • (2010) Infect Immun , vol.78 , Issue.6 , pp. 2607-2619
    • Horzempa, J.1    O'Dee, D.M.2    Shanks, R.M.3    Nau, G.J.4
  • 13
    • 33747043599 scopus 로고    scopus 로고
    • A microarray analysis of the murine macrophage response to infection with Francisella tularensis LVS
    • Andersson H, Hartmanova B, Ryden P, Noppa L, Naslund L, Sjostedt A. A microarray analysis of the murine macrophage response to infection with Francisella tularensis LVS. J Med Microbiol. 2006;55(Pt 8):1023-33.
    • (2006) J Med Microbiol , vol.55 , pp. 1023-1033
    • Andersson, H.1    Hartmanova, B.2    Ryden, P.3    Noppa, L.4    Naslund, L.5    Sjostedt, A.6
  • 14
    • 51449099913 scopus 로고    scopus 로고
    • Microarray analysis of human monocytes infected with Francisella tularensis identifies new targets of host response subversion
    • Butchar JP, Cremer TJ, Clay CD, Gavrilin MA, Wewers MD, Marsh CB, et al. Microarray analysis of human monocytes infected with Francisella tularensis identifies new targets of host response subversion. PLoS One. 2008;3(8):e2924.
    • (2008) PLoS One , vol.3 , Issue.8 , pp. e2924
    • Butchar, J.P.1    Cremer, T.J.2    Clay, C.D.3    Gavrilin, M.A.4    Wewers, M.D.5    Marsh, C.B.6
  • 15
    • 51349089526 scopus 로고    scopus 로고
    • Transcriptional profiling of Francisella tularensis infected peripheral blood mononuclear cells: a predictive tool for tularemia
    • Paranavitana C, Pittman PR, Velauthapillai M, Zelazowska E, Dasilva L. Transcriptional profiling of Francisella tularensis infected peripheral blood mononuclear cells: a predictive tool for tularemia. FEMS Immunol Med Microbiol. 2008;54(1):92-103.
    • (2008) FEMS Immunol Med Microbiol , vol.54 , Issue.1 , pp. 92-103
    • Paranavitana, C.1    Pittman, P.R.2    Velauthapillai, M.3    Zelazowska, E.4    Dasilva, L.5
  • 17
    • 33645096658 scopus 로고    scopus 로고
    • Transcriptional profiling of host responses in mouse lungs following aerosol infection with type A Francisella tularensis
    • Andersson H, Hartmanova B, Kuolee R, Ryden P, Conlan W, Chen W, et al. Transcriptional profiling of host responses in mouse lungs following aerosol infection with type A Francisella tularensis. J Med Microbiol. 2006;55(Pt 3):263-71.
    • (2006) J Med Microbiol , vol.55 , pp. 263-271
    • Andersson, H.1    Hartmanova, B.2    Kuolee, R.3    Ryden, P.4    Conlan, W.5    Chen, W.6
  • 18
    • 84858001233 scopus 로고    scopus 로고
    • Gene expression following low dose inhalational Francisella tularensis (SchuS4) exposure in Balb/c mice and the potential role of the epithelium and cell adhesion
    • David J, Gates AJ, Griffiths GD, Lukaszewski RA. Gene expression following low dose inhalational Francisella tularensis (SchuS4) exposure in Balb/c mice and the potential role of the epithelium and cell adhesion. Microbes Infect. 2012;14(4):369-79.
    • (2012) Microbes Infect , vol.14 , Issue.4 , pp. 369-379
    • David, J.1    Gates, A.J.2    Griffiths, G.D.3    Lukaszewski, R.A.4
  • 19
    • 78951486676 scopus 로고    scopus 로고
    • Genetic identification of unique immunological responses in mice infected with virulent and attenuated Francisella tularensis
    • Kingry LC, Troyer RM, Marlenee NL, Bielefeldt-Ohmann H, Bowen RA, Schenkel AR, et al. Genetic identification of unique immunological responses in mice infected with virulent and attenuated Francisella tularensis. Microbes Infect. 2011;13(3):261-75.
    • (2011) Microbes Infect , vol.13 , Issue.3 , pp. 261-275
    • Kingry, L.C.1    Troyer, R.M.2    Marlenee, N.L.3    Bielefeldt-Ohmann, H.4    Bowen, R.A.5    Schenkel, A.R.6
  • 20
    • 84901381099 scopus 로고    scopus 로고
    • Identification of the key differential transcriptional responses of human whole blood following TLR2 or TLR4 ligation in-vitro
    • Blankley S, Graham CM, Howes A, Bloom CI, Berry MP, Chaussabel D, et al. Identification of the key differential transcriptional responses of human whole blood following TLR2 or TLR4 ligation in-vitro. PLoS One. 2014;9(5):e97702.
    • (2014) PLoS One , vol.9 , Issue.5 , pp. e97702
    • Blankley, S.1    Graham, C.M.2    Howes, A.3    Bloom, C.I.4    Berry, M.P.5    Chaussabel, D.6
  • 21
    • 13444257582 scopus 로고    scopus 로고
    • Regulation of lipopolysaccharide-inducible genes by MyD88 and Toll/IL-1 domain containing adaptor inducing IFN-beta
    • Hirotani T, Yamamoto M, Kumagai Y, Uematsu S, Kawase I, Takeuchi O, et al. Regulation of lipopolysaccharide-inducible genes by MyD88 and Toll/IL-1 domain containing adaptor inducing IFN-beta. Biochem Biophys Res Commun. 2005;328(2):383-92.
    • (2005) Biochem Biophys Res Commun , vol.328 , Issue.2 , pp. 383-392
    • Hirotani, T.1    Yamamoto, M.2    Kumagai, Y.3    Uematsu, S.4    Kawase, I.5    Takeuchi, O.6
  • 23
    • 84877783024 scopus 로고    scopus 로고
    • Francisella tularensis subsp. tularensis induces a unique pulmonary inflammatory response: role of bacterial gene expression in temporal regulation of host defense responses
    • Walters KA, Olsufka R, Kuestner RE, Cho JH, Li H, Zornetzer GA, et al. Francisella tularensis subsp. tularensis induces a unique pulmonary inflammatory response: role of bacterial gene expression in temporal regulation of host defense responses. PLoS One. 2013;8(5):e62412.
    • (2013) PLoS One , vol.8 , Issue.5 , pp. e62412
    • Walters, K.A.1    Olsufka, R.2    Kuestner, R.E.3    Cho, J.H.4    Li, H.5    Zornetzer, G.A.6
  • 24
    • 33845496485 scopus 로고    scopus 로고
    • Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors
    • Hajjar AM, Harvey MD, Shaffer SA, Goodlett DR, Sjostedt A, Edebro H, et al. Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors. Infect Immun. 2006;74(12):6730-8.
    • (2006) Infect Immun , vol.74 , Issue.12 , pp. 6730-6738
    • Hajjar, A.M.1    Harvey, M.D.2    Shaffer, S.A.3    Goodlett, D.R.4    Sjostedt, A.5    Edebro, H.6
  • 25
    • 84902956964 scopus 로고    scopus 로고
    • Lung cell-specific modulation of LPS-induced TLR4 receptor and adaptor localization
    • Sender V, Stamme C. Lung cell-specific modulation of LPS-induced TLR4 receptor and adaptor localization. Commun Integr Biol. 2014;7:e29053.
    • (2014) Commun Integr Biol , vol.7 , pp. e29053
    • Sender, V.1    Stamme, C.2
  • 26
    • 34547560557 scopus 로고    scopus 로고
    • oPOSSUM: integrated tools for analysis of regulatory motif over-representation
    • Ho Sui SJ, Fulton DL, Arenillas DJ, Kwon AT, Wasserman WW. oPOSSUM: integrated tools for analysis of regulatory motif over-representation. Nucleic Acids Res. 2007;35(Web Server issue):W245-252.
    • (2007) Nucleic Acids Res , vol.35 , Issue.WEB SERVER ISSUE , pp. W245-252
    • Ho Sui, S.J.1    Fulton, D.L.2    Arenillas, D.J.3    Kwon, A.T.4    Wasserman, W.W.5
  • 27
    • 20144370200 scopus 로고    scopus 로고
    • oPOSSUM: identification of over-represented transcription factor binding sites in co-expressed genes
    • Ho Sui SJ, Mortimer JR, Arenillas DJ, Brumm J, Walsh CJ, Kennedy BP, et al. oPOSSUM: identification of over-represented transcription factor binding sites in co-expressed genes. Nucleic Acids Res. 2005;33(10):3154-64.
    • (2005) Nucleic Acids Res , vol.33 , Issue.10 , pp. 3154-3164
    • Ho Sui, S.J.1    Mortimer, J.R.2    Arenillas, D.J.3    Brumm, J.4    Walsh, C.J.5    Kennedy, B.P.6
  • 28
    • 77950353500 scopus 로고    scopus 로고
    • The murine IL-8 homologues KC, MIP-2, and LIX are found in endothelial cytoplasmic granules but not in Weibel-Palade bodies
    • Hol J, Wilhelmsen L, Haraldsen G. The murine IL-8 homologues KC, MIP-2, and LIX are found in endothelial cytoplasmic granules but not in Weibel-Palade bodies. J Leukoc Biol. 2010;87(3):501-8.
    • (2010) J Leukoc Biol , vol.87 , Issue.3 , pp. 501-508
    • Hol, J.1    Wilhelmsen, L.2    Haraldsen, G.3
  • 29
    • 38449112889 scopus 로고    scopus 로고
    • The role of chemokines in neutrophil biology
    • Kobayashi Y. The role of chemokines in neutrophil biology. Front Biosci. 2008;13:2400-7.
    • (2008) Front Biosci , vol.13 , pp. 2400-2407
    • Kobayashi, Y.1
  • 30
    • 77958487596 scopus 로고    scopus 로고
    • The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes
    • Husebye H, Aune MH, Stenvik J, Samstad E, Skjeldal F, Halaas O, et al. The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes. Immunity. 2010;33(4):583-96.
    • (2010) Immunity , vol.33 , Issue.4 , pp. 583-596
    • Husebye, H.1    Aune, M.H.2    Stenvik, J.3    Samstad, E.4    Skjeldal, F.5    Halaas, O.6
  • 31
    • 57349126161 scopus 로고    scopus 로고
    • The early phagosomal stage of Francisella tularensis determines optimal phagosomal escape and Francisella pathogenicity island protein expression
    • Chong A, Wehrly TD, Nair V, Fischer ER, Barker JR, Klose KE, et al. The early phagosomal stage of Francisella tularensis determines optimal phagosomal escape and Francisella pathogenicity island protein expression. Infect Immun. 2008;76(12):5488-99.
    • (2008) Infect Immun , vol.76 , Issue.12 , pp. 5488-5499
    • Chong, A.1    Wehrly, T.D.2    Nair, V.3    Fischer, E.R.4    Barker, J.R.5    Klose, K.E.6
  • 32
    • 78650642949 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase activation attenuates the TLR2-mediated macrophage proinflammatory cytokine response to Francisella tularensis live vaccine strain
    • Medina EA, Morris IR, Berton MT. Phosphatidylinositol 3-kinase activation attenuates the TLR2-mediated macrophage proinflammatory cytokine response to Francisella tularensis live vaccine strain. J Immunol. 2010;185(12):7562-72.
    • (2010) J Immunol , vol.185 , Issue.12 , pp. 7562-7572
    • Medina, E.A.1    Morris, I.R.2    Berton, M.T.3
  • 34
    • 2542552050 scopus 로고    scopus 로고
    • Virulent and avirulent strains of Francisella tularensis prevent acidification and maturation of their phagosomes and escape into the cytoplasm in human macrophages
    • Clemens DL, Lee BY, Horwitz MA. Virulent and avirulent strains of Francisella tularensis prevent acidification and maturation of their phagosomes and escape into the cytoplasm in human macrophages. Infect Immun. 2004;72(6):3204-17.
    • (2004) Infect Immun , vol.72 , Issue.6 , pp. 3204-3217
    • Clemens, D.L.1    Lee, B.Y.2    Horwitz, M.A.3
  • 36
    • 84886735611 scopus 로고    scopus 로고
    • Lipids derived from virulent Francisella tularensis broadly inhibit pulmonary inflammation via toll-like receptor 2 and peroxisome proliferator-activated receptor alpha
    • Crane DD, Ireland R, Alinger JB, Small P, Bosio CM. Lipids derived from virulent Francisella tularensis broadly inhibit pulmonary inflammation via toll-like receptor 2 and peroxisome proliferator-activated receptor alpha. Clin Vaccine Immunol. 2013;20(10):1531-40.
    • (2013) Clin Vaccine Immunol , vol.20 , Issue.10 , pp. 1531-1540
    • Crane, D.D.1    Ireland, R.2    Alinger, J.B.3    Small, P.4    Bosio, C.M.5
  • 37
    • 0037830766 scopus 로고    scopus 로고
    • Genome-wide DNA microarray analysis of Francisella tularensis strains demonstrates extensive genetic conservation within the species but identifies regions that are unique to the highly virulent F. tularensis subsp. tularensis
    • Broekhuijsen M, Larsson P, Johansson A, Bystrom M, Eriksson U, Larsson E, et al. Genome-wide DNA microarray analysis of Francisella tularensis strains demonstrates extensive genetic conservation within the species but identifies regions that are unique to the highly virulent F. tularensis subsp. tularensis. J Clin Microbiol. 2003;41(7):2924-31.
    • (2003) J Clin Microbiol , vol.41 , Issue.7 , pp. 2924-2931
    • Broekhuijsen, M.1    Larsson, P.2    Johansson, A.3    Bystrom, M.4    Eriksson, U.5    Larsson, E.6
  • 38
    • 77949500446 scopus 로고    scopus 로고
    • MiR-155 induction by F. novicida but not the virulent F. tularensis results in SHIP down-regulation and enhanced pro-inflammatory cytokine response
    • Cremer TJ, Ravneberg DH, Clay CD, Piper-Hunter MG, Marsh CB, Elton TS, et al. MiR-155 induction by F. novicida but not the virulent F. tularensis results in SHIP down-regulation and enhanced pro-inflammatory cytokine response. PLoS One. 2009;4(12):e8508.
    • (2009) PLoS One , vol.4 , Issue.12 , pp. e8508
    • Cremer, T.J.1    Ravneberg, D.H.2    Clay, C.D.3    Piper-Hunter, M.G.4    Marsh, C.B.5    Elton, T.S.6
  • 39
    • 33646189808 scopus 로고    scopus 로고
    • Targeting the secretory pathway for anti-inflammatory drug development
    • Ludwig JW, Richards ML. Targeting the secretory pathway for anti-inflammatory drug development. Curr Top Med Chem. 2006;6(2):165-78.
    • (2006) Curr Top Med Chem , vol.6 , Issue.2 , pp. 165-178
    • Ludwig, J.W.1    Richards, M.L.2
  • 40
    • 84885339917 scopus 로고    scopus 로고
    • Generation of membrane structures during phagocytosis and chemotaxis of macrophages: role and regulation of the actin cytoskeleton
    • Rougerie P, Miskolci V, Cox D. Generation of membrane structures during phagocytosis and chemotaxis of macrophages: role and regulation of the actin cytoskeleton. Immunol Rev. 2013;256(1):222-39.
    • (2013) Immunol Rev , vol.256 , Issue.1 , pp. 222-239
    • Rougerie, P.1    Miskolci, V.2    Cox, D.3
  • 41
    • 77955876086 scopus 로고    scopus 로고
    • Actin on DNA-an ancient and dynamic relationship
    • Skarp KP, Vartiainen MK. Actin on DNA-an ancient and dynamic relationship. Cytoskeleton. 2010;67(8):487-95.
    • (2010) Cytoskeleton , vol.67 , Issue.8 , pp. 487-495
    • Skarp, K.P.1    Vartiainen, M.K.2
  • 42
  • 43
    • 80053951342 scopus 로고    scopus 로고
    • Pathogens and polymers: microbe-host interactions illuminate the cytoskeleton
    • Haglund CM, Welch MD. Pathogens and polymers: microbe-host interactions illuminate the cytoskeleton. J Cell Biol. 2011;195(1):7-17.
    • (2011) J Cell Biol , vol.195 , Issue.1 , pp. 7-17
    • Haglund, C.M.1    Welch, M.D.2
  • 45
    • 23944445646 scopus 로고    scopus 로고
    • Francisella tularensis enters macrophages via a novel process involving pseudopod loops
    • Clemens DL, Lee BY, Horwitz MA. Francisella tularensis enters macrophages via a novel process involving pseudopod loops. Infect Immun. 2005;73(9):5892-902.
    • (2005) Infect Immun , vol.73 , Issue.9 , pp. 5892-5902
    • Clemens, D.L.1    Lee, B.Y.2    Horwitz, M.A.3
  • 46
    • 65449134827 scopus 로고    scopus 로고
    • Francisella tularensis phagosomal escape does not require acidification of the phagosome
    • Clemens DL, Lee BY, Horwitz MA. Francisella tularensis phagosomal escape does not require acidification of the phagosome. Infect Immun. 2009;77(5):1757-73.
    • (2009) Infect Immun , vol.77 , Issue.5 , pp. 1757-1773
    • Clemens, D.L.1    Lee, B.Y.2    Horwitz, M.A.3
  • 47
    • 0033952703 scopus 로고    scopus 로고
    • Tlr4: central component of the sole mammalian LPS sensor
    • Beutler B. Tlr4: central component of the sole mammalian LPS sensor. Curr Opin Immunol. 2000;12(1):20-6.
    • (2000) Curr Opin Immunol , vol.12 , Issue.1 , pp. 20-26
    • Beutler, B.1
  • 48
    • 33745946291 scopus 로고    scopus 로고
    • Toll-like receptors TLR2 and TLR4 initiate the innate immune response of the renal tubular epithelium to bacterial products
    • Chowdhury P, Sacks SH, Sheerin NS. Toll-like receptors TLR2 and TLR4 initiate the innate immune response of the renal tubular epithelium to bacterial products. Clin Exp Immunol. 2006;145(2):346-56.
    • (2006) Clin Exp Immunol , vol.145 , Issue.2 , pp. 346-356
    • Chowdhury, P.1    Sacks, S.H.2    Sheerin, N.S.3
  • 49
    • 84883790050 scopus 로고    scopus 로고
    • Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock
    • Hagar JA, Powell DA, Aachoui Y, Ernst RK, Miao EA. Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock. Sci. 2013;341(6151):1250-3.
    • (2013) Sci , vol.341 , Issue.6151 , pp. 1250-1253
    • Hagar, J.A.1    Powell, D.A.2    Aachoui, Y.3    Ernst, R.K.4    Miao, E.A.5
  • 50
    • 84883775365 scopus 로고    scopus 로고
    • Noncanonical inflammasome activation by intracellular LPS independent of TLR4
    • Kayagaki N, Wong MT, Stowe IB, Ramani SR, Gonzalez LC, Akashi-Takamura S, et al. Noncanonical inflammasome activation by intracellular LPS independent of TLR4. Sci. 2013;341(6151):1246-9.
    • (2013) Sci , vol.341 , Issue.6151 , pp. 1246-1249
    • Kayagaki, N.1    Wong, M.T.2    Stowe, I.B.3    Ramani, S.R.4    Gonzalez, L.C.5    Akashi-Takamura, S.6
  • 51
    • 77954005130 scopus 로고    scopus 로고
    • Endogenous ligands of TLR2 and TLR4: agonists or assistants?
    • Erridge C. Endogenous ligands of TLR2 and TLR4: agonists or assistants? J Leukoc Biol. 2010;87(6):989-99.
    • (2010) J Leukoc Biol , vol.87 , Issue.6 , pp. 989-999
    • Erridge, C.1
  • 52
    • 57349174394 scopus 로고    scopus 로고
    • Infected-host-cell repertoire and cellular response in the lung following inhalation of Francisella tularensis Schu S4, LVS, or U112
    • Hall JD, Woolard MD, Gunn BM, Craven RR, Taft-Benz S, Frelinger JA, et al. Infected-host-cell repertoire and cellular response in the lung following inhalation of Francisella tularensis Schu S4, LVS, or U112. Infect Immun. 2008;76(12):5843-52.
    • (2008) Infect Immun , vol.76 , Issue.12 , pp. 5843-5852
    • Hall, J.D.1    Woolard, M.D.2    Gunn, B.M.3    Craven, R.R.4    Taft-Benz, S.5    Frelinger, J.A.6
  • 53
    • 67049143986 scopus 로고    scopus 로고
    • Francisella tularensis directly interacts with the endothelium and recruits neutrophils with a blunted inflammatory phenotype
    • Moreland JG, Hook JS, Bailey G, Ulland T, Nauseef WM. Francisella tularensis directly interacts with the endothelium and recruits neutrophils with a blunted inflammatory phenotype. Am J Physiol Lung Cell Mol Physiol. 2009;296(6):L1076-1084.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.296 , Issue.6 , pp. L1076-1084
    • Moreland, J.G.1    Hook, J.S.2    Bailey, G.3    Ulland, T.4    Nauseef, W.M.5
  • 55
    • 84877105539 scopus 로고    scopus 로고
    • LPS-mediated endothelial activation in pulmonary endothelial cells: role of Nox2-dependent IKK-beta phosphorylation
    • Menden H, Tate E, Hogg N, Sampath V. LPS-mediated endothelial activation in pulmonary endothelial cells: role of Nox2-dependent IKK-beta phosphorylation. Am J Physiol Lung Cell Mol Physiol. 2013;304(6):L445-455.
    • (2013) Am J Physiol Lung Cell Mol Physiol , vol.304 , Issue.6 , pp. L445-455
    • Menden, H.1    Tate, E.2    Hogg, N.3    Sampath, V.4
  • 56
    • 79960305949 scopus 로고    scopus 로고
    • Innate immune responses to bacterial ligands in the peripheral human lung--role of alveolar epithelial TLR expression and signalling
    • Thorley AJ, Grandolfo D, Lim E, Goldstraw P, Young A, Tetley TD. Innate immune responses to bacterial ligands in the peripheral human lung--role of alveolar epithelial TLR expression and signalling. PLoS One. 2011;6(7):e21827.
    • (2011) PLoS One , vol.6 , Issue.7 , pp. e21827
    • Thorley, A.J.1    Grandolfo, D.2    Lim, E.3    Goldstraw, P.4    Young, A.5    Tetley, T.D.6
  • 57
    • 1542617932 scopus 로고    scopus 로고
    • Cutting edge: myeloid differentiation factor 88 is essential for pulmonary host defense against Pseudomonas aeruginosa but not Staphylococcus aureus
    • Skerrett SJ, Liggitt HD, Hajjar AM, Wilson CB. Cutting edge: myeloid differentiation factor 88 is essential for pulmonary host defense against Pseudomonas aeruginosa but not Staphylococcus aureus. J Immunol. 2004;172(6):3377-81.
    • (2004) J Immunol , vol.172 , Issue.6 , pp. 3377-3381
    • Skerrett, S.J.1    Liggitt, H.D.2    Hajjar, A.M.3    Wilson, C.B.4
  • 58
    • 0032127279 scopus 로고    scopus 로고
    • Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function
    • Adachi O, Kawai T, Takeda K, Matsumoto M, Tsutsui H, Sakagami M, et al. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity. 1998;9(1):143-50.
    • (1998) Immunity , vol.9 , Issue.1 , pp. 143-150
    • Adachi, O.1    Kawai, T.2    Takeda, K.3    Matsumoto, M.4    Tsutsui, H.5    Sakagami, M.6
  • 59
    • 0043176281 scopus 로고    scopus 로고
    • Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
    • Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, Sanjo H, et al. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Sci. 2003;301(5633):640-3.
    • (2003) Sci , vol.301 , Issue.5633 , pp. 640-643
    • Yamamoto, M.1    Sato, S.2    Hemmi, H.3    Hoshino, K.4    Kaisho, T.5    Sanjo, H.6
  • 60
    • 0036353165 scopus 로고    scopus 로고
    • Different host defences are required to protect mice from primary systemic vs pulmonary infection with the facultative intracellular bacterial pathogen, Francisella tularensis LVS
    • Conlan JW, KuoLee R, Shen H, Webb A. Different host defences are required to protect mice from primary systemic vs pulmonary infection with the facultative intracellular bacterial pathogen, Francisella tularensis LVS. Microb Pathog. 2002;32(3):127-34.
    • (2002) Microb Pathog , vol.32 , Issue.3 , pp. 127-134
    • Conlan, J.W.1    KuoLee, R.2    Shen, H.3    Webb, A.4
  • 61
    • 84874840442 scopus 로고    scopus 로고
    • Growth conditions and environmental factors impact aerosolization but not virulence of Francisella tularensis infection in mice
    • Faith SA, Smith LP, Swatland AS, Reed DS. Growth conditions and environmental factors impact aerosolization but not virulence of Francisella tularensis infection in mice. Front Cell Infect Microbiol. 2012;2:126.
    • (2012) Front Cell Infect Microbiol , vol.2 , pp. 126
    • Faith, S.A.1    Smith, L.P.2    Swatland, A.S.3    Reed, D.S.4
  • 62
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar R, Domrachev M, Lash AE. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res. 2002;30(1):207-10.
    • (2002) Nucleic Acids Res , vol.30 , Issue.1 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 63
    • 42949106104 scopus 로고    scopus 로고
    • Rapid polymerase chain reaction-based screening assay for bacterial biothreat agents
    • Yang S, Rothman RE, Hardick J, Kuroki M, Hardick A, Doshi V, et al. Rapid polymerase chain reaction-based screening assay for bacterial biothreat agents. Acad Emerg Med. 2008;15(4):388-92.
    • (2008) Acad Emerg Med , vol.15 , Issue.4 , pp. 388-392
    • Yang, S.1    Rothman, R.E.2    Hardick, J.3    Kuroki, M.4    Hardick, A.5    Doshi, V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.