The oncogenic potential of BK-polyomavirus is linked to viral integration into the human genome

Journal of Pathology

Volumn 237, Issue 3, 2015, Pages 379-389

  Kenan, Daniel J ^a   Mieczkowski, Piotr A ^a   Burger Calderon, Raquel ^b   Singh, Harsharan K ^a   Nickeleit, Volker ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

BK virus; carcinoma; cell transformation, neoplastic; kidney transplantation; large T Antigen; oncogenesis; polyomavirus; polyomavirus nephropathy; virus integration

Indexed keywords

DNA; METHYLPREDNISOLONE; MYCOPHENOLATE MOFETIL; PROTEIN VP1; TACROLIMUS; VIRUS LARGE T ANTIGEN; CAPSID PROTEIN; CARRIER PROTEIN; MYOSIN-BINDING PROTEIN C; ONCOPROTEIN; VIRUS T ANTIGEN; VP1 PROTEIN, POLYOMAVIRUS;

ADULT; ARTICLE; BK VIRUS; CASE REPORT; CHROMOSOME 12; CONTROLLED STUDY; EXON; GENE EXPRESSION; GRAFT VERSUS HOST REACTION; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN GENOME; HUMAN TISSUE; HYPERTENSION NEPHROPATHY; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY ALLOGRAFT; KIDNEY DISEASE; MALE; MIDDLE AGED; MYOSIN BINDING PROTEIN C1 GENE; NONHUMAN; PRIORITY JOURNAL; TRANSITIONAL CELL CARCINOMA; TUMOR CELL; VIRUS DNA CELL DNA INTERACTION; VIRUS GENE; VIRUS ONCOGENE; VIRUS REPLICATION; ADVERSE EFFECTS; ALLOGRAFT; BIOPSY; CARCINOMA; CELL PROLIFERATION; ELECTRON MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; GENOMIC INSTABILITY; KIDNEY NEOPLASMS; KIDNEY TRANSPLANTATION; METABOLISM; MOLECULAR DIAGNOSIS; PATHOGENICITY; PATHOLOGY; POLYOMAVIRUS INFECTION; UROTHELIUM; VIROLOGY; VIRUS CELL TRANSFORMATION; VIRUS INFECTION;

ALLOGRAFTS; ANTIGENS, VIRAL, TUMOR; BIOPSY; BK VIRUS; CAPSID PROTEINS; CARCINOMA; CARRIER PROTEINS; CELL PROLIFERATION; CELL TRANSFORMATION, VIRAL; CHROMOSOMES, HUMAN, PAIR 12; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE EXPRESSION REGULATION, VIRAL; GENOME, HUMAN; GENOMIC INSTABILITY; HUMANS; KIDNEY NEOPLASMS; KIDNEY TRANSPLANTATION; MALE; MICROSCOPY, ELECTRON; MIDDLE AGED; MOLECULAR DIAGNOSTIC TECHNIQUES; ONCOGENE PROTEINS, VIRAL; POLYOMAVIRUS INFECTIONS; TUMOR VIRUS INFECTIONS; UROTHELIUM; VIRUS INTEGRATION; VIRUS REPLICATION;

EID: 84945493013     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4584     Document Type: Article

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