Risk assessment for polyomavirus nephropathy using urine cytology and the detection of decoy cells: Cheap and efficient

Transplantation

Volumn 94, Issue 7, 2012, Pages

  Nickeleit, Volker ^a   True, Karin ^a   Detwiler, Randal ^a   Kozlowski, Tomasz ^a   Singh, Harsharan ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BK VIRUS INFECTION; COST EFFECTIVENESS ANALYSIS; CYTOMEGALOVIRUS INFECTION; CYTOPATHOLOGY; EARLY DIAGNOSIS; EPSTEIN BARR VIRUS INFECTION; GRAFT RECIPIENT; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; INFECTION RISK; KIDNEY ALLOGRAFT; KIDNEY BIOPSY; KIDNEY INFECTION; LETTER; OUTCOME ASSESSMENT; POLYMERASE CHAIN REACTION; POLYOMAVIRUS INFECTION; PREDICTIVE VALUE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RENAL GRAFT DYSFUNCTION; REPEAT PROCEDURE; RISK ASSESSMENT; RISK FACTOR; SCREENING TEST; URINALYSIS; URINE CYTOLOGY; VIREMIA; VIRUS ACTIVATION; VIRUS DETECTION;

BK VIRUS; CYTOLOGICAL TECHNIQUES; HUMANS; KIDNEY TRANSPLANTATION; POLYOMAVIRUS INFECTIONS; TUMOR VIRUS INFECTIONS; URINE;

EID: 84867270629     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e31826784d8     Document Type: Letter

References (14)

1. Nickeleit V, Mihatsch MJ. Polyomavirus nephropathy in native kidneys and renal allografts: an update on an escalating threat. Transpl Int 2006; 19: 960.
2. Nickeleit V, Hirsch HH, Binet IF, et al. Polyomavirus infection of renal allograft recipients: from latent infection to manifest disease. J Am Soc Nephrol 1999; 10: 1080.
3. Nickeleit V, Hirsch HH, Zeiler M, et al. BKvirus nephropathy in renal transplantsV tubular necrosis, MHC-class II expression and rejection in a puzzling game. Nephrol Dial Transplant 2000; 15: 324.
4. Nickeleit V, Steiger J, Mihatsch MJ. Re: noninvasive diagnosis of BK virus nephritis by measurement of messenger RNA for BK virus VP1. Transplantation 2003; 75: 2160.
5. Nickeleit V, Klimkait T, Binet IF, et al. Testing for polyomavirus type BK DNA in plasma to identify renal allograft recipients with viral nephropathy. The New England Journal of Medicine 2000; 342: 1309.
6. Nickeleit V, Steiger J, Mihatsch MJ. BK virus infection after kidney transplantation. Graft 2002; 5(December suppl): S46.
7. Singh HK, Andreoni KA, Madden V, et al. Presence of urinary Haufen accurately predicts polyomavirus nephropathy. J Am Soc Nephrol 2009; 20: 416.
8. Hirsch HH, Brennan DC, Drachenberg CB, et al. Polyomavirus-associated nephropathy in renal transplantation: interdisciplinary analyses and recommendations. Transplantation 2005; 79: 1277.
9. Hirsch HH, Knowles W, Dickenmann M, et al. Prospective study of polyomavirus type BK replication and nephropathy in renal-transplant recipients. The New England Journal of Medicine 2002; 347: 488.
10. Hirsch HH, Randhawa P. BK virus in solid organ transplant recipients. Am J Transplant 2009; 9(suppl 4): S136.
11. Chakera A, Dyar OJ, Hughes E, et al. Detection of polyomavirus BK reactivation after renal transplantation using an intensive decoy cell surveillance program is costeffective. Transplantation 2011; 92: 1018.
12. Binet I, Nickeleit V, Hirsch HH, et al. Polyomavirus disease under new immunosuppressive drugs: a cause of renal graft dysfunction and graft loss. Transplantation 1999; 67: 918.
13. Singh HK, Bubendorf L, Mihatsch MJ, et al. Urine cytology findings of polyomavirus infections. Adv ExpMed Biol 2006; 577: 201.
14. Singh HK, Donna Thompson B, Nickeleit V. Viral Haufen are urinary biomarkers of polyomavirus nephropathy: new diagnostic strategies utilizing negative staining electron microscopy. Ultrastruct Pathol 2009; 33: 222.