-
1
-
-
0033979599
-
Nephrotoxicity of immunosuppressive drugs: long-term consequences and challenges for the future
-
de Mattos A.M., Olyaei A.J., Bennett W.M. Nephrotoxicity of immunosuppressive drugs: long-term consequences and challenges for the future. Am. J. Kidney Dis. 2000, 35:333-346.
-
(2000)
Am. J. Kidney Dis.
, vol.35
, pp. 333-346
-
-
de Mattos, A.M.1
Olyaei, A.J.2
Bennett, W.M.3
-
2
-
-
0035659395
-
Nephrotoxicity of immunosuppressive drugs: new insight and preventive strategies
-
Olyaei A.J., de Mattos A.M., Bennett W.M. Nephrotoxicity of immunosuppressive drugs: new insight and preventive strategies. Curr. Opin. Crit. Care 2001, 7:384-389.
-
(2001)
Curr. Opin. Crit. Care
, vol.7
, pp. 384-389
-
-
Olyaei, A.J.1
de Mattos, A.M.2
Bennett, W.M.3
-
3
-
-
34249908092
-
Immunosuppressive therapy and malignancy in organ transplant recipients: a systematic review
-
Gutierrez-Dalmau A., Campistol J.M. Immunosuppressive therapy and malignancy in organ transplant recipients: a systematic review. Drugs 2007, 67:1167-1198.
-
(2007)
Drugs
, vol.67
, pp. 1167-1198
-
-
Gutierrez-Dalmau, A.1
Campistol, J.M.2
-
4
-
-
19244366256
-
Sirolimus does not exhibit nephrotoxicity compared to cyclosporine in renal transplant recipients
-
Morales J.M., Wramner L., Kreis H., Durand D., Campistol J.M., Andres A., Arenas J., Negre E., Burke J.T., Groth C.G. Sirolimus does not exhibit nephrotoxicity compared to cyclosporine in renal transplant recipients. Am. J. Transplant. 2002, 2:436-442.
-
(2002)
Am. J. Transplant.
, vol.2
, pp. 436-442
-
-
Morales, J.M.1
Wramner, L.2
Kreis, H.3
Durand, D.4
Campistol, J.M.5
Andres, A.6
Arenas, J.7
Negre, E.8
Burke, J.T.9
Groth, C.G.10
-
5
-
-
0026575932
-
The mechanism of action of cyclosporin A and FK506
-
Schreiber S.L., Crabtree G.R. The mechanism of action of cyclosporin A and FK506. Immunol. Today 1992, 13:136-142.
-
(1992)
Immunol. Today
, vol.13
, pp. 136-142
-
-
Schreiber, S.L.1
Crabtree, G.R.2
-
6
-
-
8344281974
-
Targeting the molecular target of rapamycin (mTOR)
-
Rowinsky E.K. Targeting the molecular target of rapamycin (mTOR). Curr. Opin. Oncol. 2004, 16:564-575.
-
(2004)
Curr. Opin. Oncol.
, vol.16
, pp. 564-575
-
-
Rowinsky, E.K.1
-
7
-
-
27644436740
-
Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies
-
Kauffman H.M., Cherikh W.S., Cheng Y., Hanto D.W., Kahan B.D. Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies. Transplantation 2005, 80:883-889.
-
(2005)
Transplantation
, vol.80
, pp. 883-889
-
-
Kauffman, H.M.1
Cherikh, W.S.2
Cheng, Y.3
Hanto, D.W.4
Kahan, B.D.5
-
8
-
-
78349313076
-
The potential benefits of rapamycin on renal function, tolerance, fibrosis, and malignancy following transplantation
-
Geissler E.K., Schlitt H.J. The potential benefits of rapamycin on renal function, tolerance, fibrosis, and malignancy following transplantation. Kidney Int. 2010, 78:1075-1079.
-
(2010)
Kidney Int.
, vol.78
, pp. 1075-1079
-
-
Geissler, E.K.1
Schlitt, H.J.2
-
9
-
-
84864531704
-
Immunosuppressive drugs on inducing Ag-specific CD4(+)CD25(+)Foxp3(+) Treg cells during immune response in vivo
-
Wu T., Zhang L., Xu K., Sun C., Lei T., Peng J., Liu G., Wang R., Zhao Y. Immunosuppressive drugs on inducing Ag-specific CD4(+)CD25(+)Foxp3(+) Treg cells during immune response in vivo. Transpl. Immunol. 2012, 27:30-38.
-
(2012)
Transpl. Immunol.
, vol.27
, pp. 30-38
-
-
Wu, T.1
Zhang, L.2
Xu, K.3
Sun, C.4
Lei, T.5
Peng, J.6
Liu, G.7
Wang, R.8
Zhao, Y.9
-
10
-
-
77953674618
-
Rapamycin promotes the expansion of CD4(+) Foxp3(+) regulatory T cells after liver transplantation
-
Lu L., Qian X.F., Rao J.H., Wang X.H., Zheng S.G., Zhang F. Rapamycin promotes the expansion of CD4(+) Foxp3(+) regulatory T cells after liver transplantation. Transplant. Proc. 2010, 42:1755-1757.
-
(2010)
Transplant. Proc.
, vol.42
, pp. 1755-1757
-
-
Lu, L.1
Qian, X.F.2
Rao, J.H.3
Wang, X.H.4
Zheng, S.G.5
Zhang, F.6
-
11
-
-
34548682791
-
Reduced numbers of blood natural regulatory T cells in stable liver transplant recipients with high levels of calcineurin inhibitors
-
San Segundo D., Fabrega E., Lopez-Hoyos M., Pons F. Reduced numbers of blood natural regulatory T cells in stable liver transplant recipients with high levels of calcineurin inhibitors. Transplant. Proc. 2007, 39:2290-2292.
-
(2007)
Transplant. Proc.
, vol.39
, pp. 2290-2292
-
-
San Segundo, D.1
Fabrega, E.2
Lopez-Hoyos, M.3
Pons, F.4
-
12
-
-
33747889822
-
Calcineurin inhibitors, but not rapamycin, reduce percentages of CD4+CD25+FOXP3+ regulatory T cells in renal transplant recipients
-
Segundo D.S., Ruiz J.C., Izquierdo M., Fernandez-Fresnedo G., Gomez-Alamillo C., Merino R., Benito M.J., Cacho E., Rodrigo E., Palomar R., Lopez-Hoyos M., Arias M. Calcineurin inhibitors, but not rapamycin, reduce percentages of CD4+CD25+FOXP3+ regulatory T cells in renal transplant recipients. Transplantation 2006, 82:550-557.
-
(2006)
Transplantation
, vol.82
, pp. 550-557
-
-
Segundo, D.S.1
Ruiz, J.C.2
Izquierdo, M.3
Fernandez-Fresnedo, G.4
Gomez-Alamillo, C.5
Merino, R.6
Benito, M.J.7
Cacho, E.8
Rodrigo, E.9
Palomar, R.10
Lopez-Hoyos, M.11
Arias, M.12
-
13
-
-
20444373376
-
Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells
-
Battaglia M., Stabilini A., Roncarolo M.G. Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells. Blood 2005, 105:4743-4748.
-
(2005)
Blood
, vol.105
, pp. 4743-4748
-
-
Battaglia, M.1
Stabilini, A.2
Roncarolo, M.G.3
-
14
-
-
33845379986
-
Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients
-
Battaglia M., Stabilini A., Migliavacca B., Horejs-Hoeck J., Kaupper T., Roncarolo M.G. Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients. J. Immunol. 2006, 177:8338-8347.
-
(2006)
J. Immunol.
, vol.177
, pp. 8338-8347
-
-
Battaglia, M.1
Stabilini, A.2
Migliavacca, B.3
Horejs-Hoeck, J.4
Kaupper, T.5
Roncarolo, M.G.6
-
15
-
-
84873284170
-
Sirolimus did not affect CD4(+)CD25(high) forkhead box p3(+)T cells of peripheral blood in renal transplant recipients
-
Chu Z.Q., Ji Q. Sirolimus did not affect CD4(+)CD25(high) forkhead box p3(+)T cells of peripheral blood in renal transplant recipients. Transplant. Proc. 2013, 45:153-156.
-
(2013)
Transplant. Proc.
, vol.45
, pp. 153-156
-
-
Chu, Z.Q.1
Ji, Q.2
-
16
-
-
0038036797
-
Rapamycin inhibits IL-4-induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo
-
Hackstein H., Taner T., Zahorchak A.F., Morelli A.E., Logar A.J., Gessner A., Thomson A.W. Rapamycin inhibits IL-4-induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo. Blood 2003, 101:4457-4463.
-
(2003)
Blood
, vol.101
, pp. 4457-4463
-
-
Hackstein, H.1
Taner, T.2
Zahorchak, A.F.3
Morelli, A.E.4
Logar, A.J.5
Gessner, A.6
Thomson, A.W.7
-
17
-
-
34249805413
-
Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance
-
Turnquist H.R., Raimondi G., Zahorchak A.F., Fischer R.T., Wang Z., Thomson A.W. Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance. J. Immunol. 2007, 178:7018-7031.
-
(2007)
J. Immunol.
, vol.178
, pp. 7018-7031
-
-
Turnquist, H.R.1
Raimondi, G.2
Zahorchak, A.F.3
Fischer, R.T.4
Wang, Z.5
Thomson, A.W.6
-
18
-
-
13144256708
-
Rapamycin-treated, alloantigen-pulsed host dendritic cells induce ag-specific T cell regulation and prolong graft survival
-
Taner T., Hackstein H., Wang Z., Morelli A.E., Thomson A.W. Rapamycin-treated, alloantigen-pulsed host dendritic cells induce ag-specific T cell regulation and prolong graft survival. Am. J. Transplant. 2005, 5:228-236.
-
(2005)
Am. J. Transplant.
, vol.5
, pp. 228-236
-
-
Taner, T.1
Hackstein, H.2
Wang, Z.3
Morelli, A.E.4
Thomson, A.W.5
-
19
-
-
0036197923
-
Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation
-
Mizoguchi A., Mizoguchi E., Takedatsu H., Blumberg R.S., Bhan A.K. Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation. Immunity 2002, 16:219-230.
-
(2002)
Immunity
, vol.16
, pp. 219-230
-
-
Mizoguchi, A.1
Mizoguchi, E.2
Takedatsu, H.3
Blumberg, R.S.4
Bhan, A.K.5
-
20
-
-
84892143731
-
Regulatory B cells and tolerance in transplantation: from animal models to human
-
Chesneau M., Michel L., Degauque N., Brouard S. Regulatory B cells and tolerance in transplantation: from animal models to human. Front. Immunol. 2013, 4:497.
-
(2013)
Front. Immunol.
, vol.4
, pp. 497
-
-
Chesneau, M.1
Michel, L.2
Degauque, N.3
Brouard, S.4
-
21
-
-
80053608534
-
Regulatory cells and cell signatures in clinical transplantation tolerance
-
Newell K.A., Phippard D., Turka L.A. Regulatory cells and cell signatures in clinical transplantation tolerance. Curr. Opin. Immunol. 2011, 23:655-659.
-
(2011)
Curr. Opin. Immunol.
, vol.23
, pp. 655-659
-
-
Newell, K.A.1
Phippard, D.2
Turka, L.A.3
-
22
-
-
34250156673
-
Contrasting effects of cyclosporine and rapamycin in de novo generation of alloantigen-specific regulatory T cells
-
Gao W., Lu Y., El Essawy B., Oukka M., Kuchroo V.K., Strom T.B. Contrasting effects of cyclosporine and rapamycin in de novo generation of alloantigen-specific regulatory T cells. Am. J. Transplant. 2007, 7:1722-1732.
-
(2007)
Am. J. Transplant.
, vol.7
, pp. 1722-1732
-
-
Gao, W.1
Lu, Y.2
El Essawy, B.3
Oukka, M.4
Kuchroo, V.K.5
Strom, T.B.6
-
23
-
-
4644369302
-
Interleukin-2 is essential for CD4+CD25+ regulatory T cell function
-
de la Rosa M., Rutz S., Dorninger H., Scheffold A. Interleukin-2 is essential for CD4+CD25+ regulatory T cell function. Eur. J. Immunol. 2004, 34:2480-2488.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 2480-2488
-
-
de la Rosa, M.1
Rutz, S.2
Dorninger, H.3
Scheffold, A.4
-
24
-
-
84865302248
-
Systemic immunoregulatory and proteogenomic effects of tacrolimus to sirolimus conversion in liver transplant recipients
-
Levitsky J., Mathew J.M., Abecassis M., Tambur A., Leventhal J., Chandrasekaran D., Herrera N., Al-Saden P., Gallon L., Abdul-Nabi A., Yang G.Y., Kurian S.M., Salomon D.R., Miller J. Systemic immunoregulatory and proteogenomic effects of tacrolimus to sirolimus conversion in liver transplant recipients. Hepatology 2013, 57:239-248.
-
(2013)
Hepatology
, vol.57
, pp. 239-248
-
-
Levitsky, J.1
Mathew, J.M.2
Abecassis, M.3
Tambur, A.4
Leventhal, J.5
Chandrasekaran, D.6
Herrera, N.7
Al-Saden, P.8
Gallon, L.9
Abdul-Nabi, A.10
Yang, G.Y.11
Kurian, S.M.12
Salomon, D.R.13
Miller, J.14
-
25
-
-
85027946292
-
Allospecific regulatory effects of sirolimus and tacrolimus in the human mixed lymphocyte reaction
-
Levitsky J., Gallon L., Miller J., Tambur A.R., Leventhal J., Flaa C., Huang X., Sarraj B., Wang E., Mathew J.M. Allospecific regulatory effects of sirolimus and tacrolimus in the human mixed lymphocyte reaction. Transplantation 2011, 91:199-206.
-
(2011)
Transplantation
, vol.91
, pp. 199-206
-
-
Levitsky, J.1
Gallon, L.2
Miller, J.3
Tambur, A.R.4
Leventhal, J.5
Flaa, C.6
Huang, X.7
Sarraj, B.8
Wang, E.9
Mathew, J.M.10
-
26
-
-
84901823579
-
TGF-beta-producing regulatory B cells induce regulatory T cells and promote transplantation tolerance
-
Lee K.M., Stott R.T., Zhao G., SooHoo J., Xiong W., Lian M.M., Fitzgerald L., Shi S., Akrawi E., Lei J., Deng S., Yeh H., Markmann J.F., Kim J.I. TGF-beta-producing regulatory B cells induce regulatory T cells and promote transplantation tolerance. Eur. J. Immunol. 2014, 44:1728-1736.
-
(2014)
Eur. J. Immunol.
, vol.44
, pp. 1728-1736
-
-
Lee, K.M.1
Stott, R.T.2
Zhao, G.3
SooHoo, J.4
Xiong, W.5
Lian, M.M.6
Fitzgerald, L.7
Shi, S.8
Akrawi, E.9
Lei, J.10
Deng, S.11
Yeh, H.12
Markmann, J.F.13
Kim, J.I.14
-
27
-
-
43049156086
-
A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses
-
Yanaba K., Bouaziz J.D., Haas K.M., Poe J.C., Fujimoto M., Tedder T.F. A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses. Immunity 2008, 28:639-650.
-
(2008)
Immunity
, vol.28
, pp. 639-650
-
-
Yanaba, K.1
Bouaziz, J.D.2
Haas, K.M.3
Poe, J.C.4
Fujimoto, M.5
Tedder, T.F.6
-
28
-
-
10744232881
-
Th1/Th2 cytokine profiles and their relationship to clinical features in patients following nonmyeloablative allogeneic stem cell transplantation
-
Guo H., Qiao Z., Zhu L., Wang H., Su L., Lu Y., Cui Y., Jiang B., Zhu Q., Xu L. Th1/Th2 cytokine profiles and their relationship to clinical features in patients following nonmyeloablative allogeneic stem cell transplantation. Am. J. Hematol. 2004, 75:78-83.
-
(2004)
Am. J. Hematol.
, vol.75
, pp. 78-83
-
-
Guo, H.1
Qiao, Z.2
Zhu, L.3
Wang, H.4
Su, L.5
Lu, Y.6
Cui, Y.7
Jiang, B.8
Zhu, Q.9
Xu, L.10
-
29
-
-
27144554518
-
Ex vivo rapamycin generates donor Th2 cells that potently inhibit graft-versus-host disease and graft-versus-tumor effects via an IL-4-dependent mechanism
-
Foley J.E., Jung U., Miera A., Borenstein T., Mariotti J., Eckhaus M., Bierer B.E., Fowler D.H. Ex vivo rapamycin generates donor Th2 cells that potently inhibit graft-versus-host disease and graft-versus-tumor effects via an IL-4-dependent mechanism. J. Immunol. 2005, 175:5732-5743.
-
(2005)
J. Immunol.
, vol.175
, pp. 5732-5743
-
-
Foley, J.E.1
Jung, U.2
Miera, A.3
Borenstein, T.4
Mariotti, J.5
Eckhaus, M.6
Bierer, B.E.7
Fowler, D.H.8
-
30
-
-
63449133866
-
Both tacrolimus and sirolimus decrease Th1/Th2 ratio, and increase regulatory T lymphocytes in the liver after ischemia/reperfusion
-
Arias-Diaz J., Ildefonso J.A., Munoz J.J., Zapata A., Jimenez E. Both tacrolimus and sirolimus decrease Th1/Th2 ratio, and increase regulatory T lymphocytes in the liver after ischemia/reperfusion. Lab. Invest. 2009, 89:433-445.
-
(2009)
Lab. Invest.
, vol.89
, pp. 433-445
-
-
Arias-Diaz, J.1
Ildefonso, J.A.2
Munoz, J.J.3
Zapata, A.4
Jimenez, E.5
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