-
1
-
-
33644860571
-
Tumor suppressor genes in breast cancer: The gatekeepers and the caretakers
-
Oliveira AM, Ross JS, Fletcher JA. Tumor suppressor genes in breast cancer: the gatekeepers and the caretakers. Am J Clin Pathol 2005;124: S16-28
-
(2005)
Am J Clin Pathol
, vol.124
, pp. S16-28
-
-
Oliveira, A.M.1
Ross, J.S.2
Fletcher, J.A.3
-
2
-
-
23944510641
-
Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex
-
Varma AK, Brown RS, Birrane G, Ladias JA. Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex. Biochemistry 2005; 44:10941-6
-
(2005)
Biochemistry
, vol.44
, pp. 10941-10946
-
-
Varma, A.K.1
Brown, R.S.2
Birrane, G.3
Ladias, J.A.4
-
4
-
-
0034468241
-
Caretaker Brca1 keeping the genome in the straight and narrow
-
Yu V. Caretaker Brca1: keeping the genome in the straight and narrow. Breast Cancer Res 2000;2:82-5
-
(2000)
Breast Cancer Res
, vol.2
, pp. 82-85
-
-
Yu, V.1
-
5
-
-
0034696394
-
Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation
-
Deng CX, Scott F. Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation. Oncogene 2000;19: 1059-64
-
(2000)
Oncogene
, vol.19
, pp. 1059-1064
-
-
Deng, C.X.1
Scott, F.2
-
6
-
-
3543034637
-
The integrin-binding protein Nischarin regulates cell migration by inhibiting PAK
-
Alahari SK, Reddig PJ, Juliano RL. The integrin-binding protein Nischarin regulates cell migration by inhibiting PAK. EMBO J 2004;23:2777-88
-
(2004)
EMBO J
, vol.23
, pp. 2777-2788
-
-
Alahari, S.K.1
Reddig, P.J.2
Juliano, R.L.3
-
7
-
-
0942290434
-
A membrane proximal region of the integrin alpha5 subunit is important for its interaction with nischarin
-
Alahari SK, Nasrallah H. A membrane proximal region of the integrin alpha5 subunit is important for its interaction with nischarin. Biochem J 2004;377:449-57
-
(2004)
Biochem J
, vol.377
, pp. 449-457
-
-
Alahari, S.K.1
Nasrallah, H.2
-
8
-
-
44349130374
-
Nischarin inhibits LIM kinase to regulate cofilin phosphorylation and cell invasion
-
Ding Y, Milosavljevic T, Alahari SK. Nischarin inhibits LIM kinase to regulate cofilin phosphorylation and cell invasion. Mol Cell Biol 2008; 28:3742-56
-
(2008)
Mol Cell Biol
, vol.28
, pp. 3742-3756
-
-
Ding, Y.1
Milosavljevic, T.2
Alahari, S.K.3
-
9
-
-
1342284181
-
IRAS splice variants
-
Piletz JE, Deleersnijder W, Roth BL, Ernsberger P, Zhu H, Ziegler D. IRAS splice variants. Ann N Y Acad Sci 2003;1009:419-26
-
(2003)
Ann N y Acad Sci
, vol.1009
, pp. 419-426
-
-
Piletz, J.E.1
Deleersnijder, W.2
Roth, B.L.3
Ernsberger, P.4
Zhu, H.5
Ziegler, D.6
-
10
-
-
0034638831
-
Nischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migration
-
Alahari SK, Lee JW, Juliano RL. Nischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migration. J Cell Biol 2000;151:1141-54
-
(2000)
J Cell Biol
, vol.151
, pp. 1141-1154
-
-
Alahari, S.K.1
Lee, J.W.2
Juliano, R.L.3
-
11
-
-
84945330826
-
-
Gene Cards. Nisch Gene 2015 [cited 2015 Jul 16]
-
Gene Cards. Nisch Gene 2015 [cited 2015 Jul 16]. Available from: http://www.genecards.org/cgi-bin/carddisp.pl?gene=NISCH.
-
-
-
-
12
-
-
80054964779
-
Molecular characterization of the tumor-suppressive function of nischarin in breast cancer
-
Baranwal S, Wang Y, Rathinam R, Lee J, Jin L, McGoey R, et al. Molecular characterization of the tumor-suppressive function of nischarin in breast cancer. J Natl Cancer Inst 2011;103:1513-28
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 1513-1528
-
-
Baranwal, S.1
Wang, Y.2
Rathinam, R.3
Lee, J.4
Jin, L.5
McGoey, R.6
-
13
-
-
77954222909
-
Molecular analysis of plasma DNA for the early detection of lung cancer by quantitative methylation-specific PCR
-
Ostrow KL, Hoque MO, Loyo M, Brait M, Greenberg A, Siegfried JM, et al. Molecular analysis of plasma DNA for the early detection of lung cancer by quantitative methylation-specific PCR. Clin Cancer Res 2010; 16:3463-72
-
(2011)
Clin Cancer Res
, vol.16
, pp. 3463-3472
-
-
Ostrow, K.L.1
Hoque, M.O.2
Loyo, M.3
Brait, M.4
Greenberg, A.5
Siegfried, J.M.6
-
14
-
-
12444330899
-
IRAS, the human homologue of Nischarin, prolongs survival of transfected PC12 cells
-
Dontenwill M, Pascal G, Piletz JE, Chen M, Baldwin J, Ronde P, et al. IRAS, the human homologue of Nischarin, prolongs survival of transfected PC12 cells. Cell Death Differ 2003;10:933-5
-
(2003)
Cell Death Differ
, vol.10
, pp. 933-935
-
-
Dontenwill, M.1
Pascal, G.2
Piletz, J.E.3
Chen, M.4
Baldwin, J.5
Ronde, P.6
-
15
-
-
84940392927
-
Immunodetection and subcellular distribution of imidazoline receptor proteins with three antibodies in mouse and human brains: Effects of treatments with I1-And I2-imidazoline drugs
-
Keller B, Garcia-Sevilla JA. Immunodetection and subcellular distribution of imidazoline receptor proteins with three antibodies in mouse and human brains: effects of treatments with I1-And I2-imidazoline drugs. J Psychopharmacol 2015:1-17
-
(2015)
J Psychopharmacol
, pp. 1-17
-
-
Keller, B.1
Garcia-Sevilla, J.A.2
-
16
-
-
84945343818
-
-
NCBI. NISCH 2015 [cited 2015 Jul 16]
-
NCBI. NISCH 2015 [cited 2015 Jul 16]. Available from: http://www.ncbi. nlm.nih.gov/gene/11188
-
-
-
-
17
-
-
84945326678
-
-
UniProt. Q80TM9 (Nisch-Mouse 2015 [cited 2015 Jul 16]
-
UniProt. Q80TM9 (Nisch-Mouse) 2015 [cited 2015 Jul 16]. Available from: http://www.uniprot.org/uniprot/Q80TM9
-
-
-
-
18
-
-
84945363712
-
-
UniProt. Q9Y2I1 2015 [cited 2015 Jul 16]
-
UniProt. Q9Y2I1 2015 [cited 2015 Jul 16]. Available from: http://www. uniprot.org/uniprot/Q9Y2I1
-
-
-
-
19
-
-
11144228295
-
Human Nischarin/imidazoline receptor antiseraselected protein is targeted to the endosomes by a combined action of a PX domain and a coiled-coil region
-
Lim KP, Hong W. Human Nischarin/imidazoline receptor antiseraselected protein is targeted to the endosomes by a combined action of a PX domain and a coiled-coil region. J Biol Chem 2004;279: 54770-82
-
(2004)
J Biol Chem
, vol.279
, pp. 54770-54782
-
-
Lim, K.P.1
Hong, W.2
-
20
-
-
84878392808
-
Integrin-binding protein nischarin interacts with tumor suppressor liver kinase B1 (LKB1) to regulate cell migration of breast epithelial cells
-
Jain P, Baranwal S, Dong S, Struckhoff AP, Worthylake RA, Alahari SK. Integrin-binding protein nischarin interacts with tumor suppressor liver kinase B1 (LKB1) to regulate cell migration of breast epithelial cells. J Biol Chem 2013;288:15495-509
-
(2013)
J Biol Chem
, vol.288
, pp. 15495-15509
-
-
Jain, P.1
Baranwal, S.2
Dong, S.3
Struckhoff, A.P.4
Worthylake, R.A.5
Alahari, S.K.6
-
21
-
-
84875211797
-
Rac and Rab GTPases dual effector Nischarin regulates vesicle maturation to facilitate survival of intracellular bacteria
-
Kuijl C, Pilli M, Alahari SK, Janssen H, Khoo PS, Ervin KE, et al. Rac and Rab GTPases dual effector Nischarin regulates vesicle maturation to facilitate survival of intracellular bacteria. EMBO J 2013;32:713-27
-
(2013)
EMBO J
, vol.32
, pp. 713-727
-
-
Kuijl, C.1
Pilli, M.2
Alahari, S.K.3
Janssen, H.4
Khoo, P.S.5
Ervin, K.E.6
-
22
-
-
0037205482
-
Insulin receptor substrate 4 associates with the protein IRAS
-
Sano H, Liu SC, Lane WS, Piletz JE, Lienhard GE. Insulin receptor substrate 4 associates with the protein IRAS. J Biol Chem 2002;277: 19439-47
-
(2002)
J Biol Chem
, vol.277
, pp. 19439-19447
-
-
Sano, H.1
Liu, S.C.2
Lane, W.S.3
Piletz, J.E.4
Lienhard, G.E.5
-
24
-
-
84891751325
-
The mouse Gene Expression Database (GXD 2014 update
-
Smith CM, Finger JH, Hayamizu TF, McCright IJ, Xu J, Berghout J, et al. The mouse Gene Expression Database (GXD): 2014 update. Nucleic Acids Res 2014;42:D818-24
-
(2014)
Nucleic Acids Res
, vol.42
, pp. D818-D824
-
-
Smith, C.M.1
Finger, J.H.2
Hayamizu, T.F.3
McCright, I.J.4
Xu, J.5
Berghout, J.6
-
25
-
-
84922393807
-
Ubiquitination in disease pathogenesis and treatment
-
Popovic D, Vucic D, Dikic I. Ubiquitination in disease pathogenesis and treatment. Nat Med 2014;20:1242-53
-
(2014)
Nat Med
, vol.20
, pp. 1242-1253
-
-
Popovic, D.1
Vucic, D.2
Dikic, I.3
-
26
-
-
84945332208
-
-
Phosphositeplus. NISCH (human 2015 [cited 2015 Jul 16]
-
Phosphositeplus. NISCH (human) 2015 [cited 2015 Jul 16]. Available from: http://www.phosphosite.org/proteinAction.do?id=15675& showAllSites=true.
-
-
-
-
27
-
-
68949212379
-
Lysine acetylation targets protein complexes and co-regulates major cellular functions
-
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, et al. Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 2009;325:834-40
-
(2009)
Science
, vol.325
, pp. 834-840
-
-
Choudhary, C.1
Kumar, C.2
Gnad, F.3
Nielsen, M.L.4
Rehman, M.5
Walther, T.C.6
-
28
-
-
0033593461
-
Signaling mechanisms that regulate glucose transport
-
Czech MP, Corvera S. Signaling mechanisms that regulate glucose transport. J Biol Chem 1999;274:1865-8
-
(1999)
J Biol Chem
, vol.274
, pp. 1865-1868
-
-
Czech, M.P.1
Corvera, S.2
-
29
-
-
0032574823
-
Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity
-
Kawasome H, Papst P, Webb S, Keller GM, Johnson GL, Gelfand EW, et al. Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity. Proc Natl Acad Sci U S A 1998;95:5033-8
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 5033-5038
-
-
Kawasome, H.1
Papst, P.2
Webb, S.3
Keller, G.M.4
Johnson, G.L.5
Gelfand, E.W.6
-
30
-
-
26244464326
-
PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP
-
Porstmann T, Griffiths B, Chung YL, Delpuech O, Griffiths JR, Downward J, et al. PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP. Oncogene 2005;24:6465-81
-
(2005)
Oncogene
, vol.24
, pp. 6465-6481
-
-
Porstmann, T.1
Griffiths, B.2
Chung, Y.L.3
Delpuech, O.4
Griffiths, J.R.5
Downward, J.6
-
31
-
-
84872433294
-
Nischarin is differentially expressed in rat brain and regulates neuronal migration
-
Ding Y, Zhang R, Zhang K, Lv X, Chen Y, Li A, et al. Nischarin is differentially expressed in rat brain and regulates neuronal migration. PLoSONE2013;8: e54563
-
(2013)
PLoSONE
, vol.8
, pp. e54563
-
-
Ding, Y.1
Zhang, R.2
Zhang, K.3
Lv, X.4
Chen, Y.5
Li, A.6
-
32
-
-
84888184586
-
The expression pattern of Nischarin after lipopolysaccharides (LPS)-induced neuroinflammation in rats brain cortex
-
Wu X, Xu W, Cui G, Yan Y, Wu X, Li L, et al. The expression pattern of Nischarin after lipopolysaccharides (LPS)-induced neuroinflammation in rats brain cortex. Inflamm Res 2013;62:929-40
-
(2013)
Inflamm Res
, vol.62
, pp. 929-940
-
-
Wu, X.1
Xu, W.2
Cui, G.3
Yan, Y.4
Wu, X.5
Li, L.6
-
33
-
-
18744418553
-
A screen for genes induced in the amygdaloid area during cat odor exposure
-
Koks S, Luuk H, Nelovkov A, Areda T, Vasar E. A screen for genes induced in the amygdaloid area during cat odor exposure. Genes Brain Behav 2004;3:80-9
-
(2004)
Genes Brain Behav
, vol.3
, pp. 80-89
-
-
Koks, S.1
Luuk, H.2
Nelovkov, A.3
Areda, T.4
Vasar, E.5
-
34
-
-
37349035623
-
Inhibition of nischarin expression attenuates rilmenidine-evoked hypotension and phosphorylated extracellular signalregulated kinase 1/2 production in the rostral ventrolateral medulla of rats
-
Zhang J, Abdel-Rahman AA. Inhibition of nischarin expression attenuates rilmenidine-evoked hypotension and phosphorylated extracellular signalregulated kinase 1/2 production in the rostral ventrolateral medulla of rats. J Pharmacol Exp Ther 2008;324:72-8
-
(2008)
J Pharmacol Exp Ther
, vol.324
, pp. 72-78
-
-
Zhang, J.1
Abdel-Rahman, A.A.2
-
35
-
-
84942107493
-
Frequent loss of NISCH promotes tumor proliferation and invasion in ovarian cancer via inhibiting the FAK signal pathway
-
Li J, He X, Dong R, Wang Y, Yu J, Qiu H. Frequent loss of NISCH promotes tumor proliferation and invasion in ovarian cancer via inhibiting the FAK signal pathway. Mol Cancer Ther 2015;14:1202-12
-
(2015)
Mol Cancer Ther
, vol.14
, pp. 1202-1212
-
-
Li, J.1
He, X.2
Dong, R.3
Wang, Y.4
Yu, J.5
Qiu, H.6
-
36
-
-
84875740314
-
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
-
Gao J, Aksoy BA, Dogrusoz U, Dresdner G, Gross B, Sumer SO, et al. Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal 2013;6:pl1
-
(2013)
Sci Signal
, vol.6
, pp. pl1
-
-
Gao, J.1
Aksoy, B.A.2
Dogrusoz, U.3
Dresdner, G.4
Gross, B.5
Sumer, S.O.6
-
37
-
-
84926655034
-
Expression of integrin-binding protein Nischarin in metastatic breast cancer
-
Chen J, Feng WL, Mo WJ, Ding XW, Xie SN. Expression of integrin-binding protein Nischarin in metastatic breast cancer. Mol Med Rep 2015;12: 77-82
-
(2015)
Mol Med Rep
, vol.12
, pp. 77-82
-
-
Chen, J.1
Feng, W.L.2
Mo, W.J.3
Ding, X.W.4
Xie, S.N.5
-
38
-
-
67749111502
-
The LKB1-AMPK pathway: Metabolism and growth control in tumour suppression
-
Shackelford DB, Shaw RJ. The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nat Rev Cancer 2009;9:563-75
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 563-575
-
-
Shackelford, D.B.1
Shaw, R.J.2
-
39
-
-
84862155618
-
The role of Rac1 in the regulation of NF-kappaB activity, cell proliferation, and cell migration in non-small cell lung carcinoma
-
Gastonguay A, Berg T, Hauser AD, Schuld N, Lorimer E, Williams CL. The role of Rac1 in the regulation of NF-kappaB activity, cell proliferation, and cell migration in non-small cell lung carcinoma. Cancer Biol Ther 2012;13:647-56
-
(2012)
Cancer Biol Ther
, vol.13
, pp. 647-656
-
-
Gastonguay, A.1
Berg, T.2
Hauser, A.D.3
Schuld, N.4
Lorimer, E.5
Williams, C.L.6
-
40
-
-
24744462314
-
Regulation of p21-Activated kinase-independent Rac1 signal transduction by nischarin
-
Reddig PJ, Xu D, Juliano RL. Regulation of p21-Activated kinase-independent Rac1 signal transduction by nischarin. J Biol Chem 20053;280: 30994-1002
-
(2005)
J Biol Chem
, vol.280
, pp. 30994-31002
-
-
Reddig, P.J.1
Xu, D.2
Juliano, R.L.3
-
41
-
-
0042564472
-
Nischarin inhibits Rac induced migration and invasion of epithelial cells by affecting signaling cascades involving PAK
-
Alahari SK. Nischarin inhibits Rac induced migration and invasion of epithelial cells by affecting signaling cascades involving PAK. Exp Cell Res 2003;288:415-24
-
(2003)
Exp Cell Res
, vol.288
, pp. 415-424
-
-
Alahari, S.K.1
-
42
-
-
10744231365
-
IRAS is an anti-Apoptotic protein
-
Dontenwill M, Piletz JE, Chen M, Baldwin J, Pascal G, Ronde P, et al. IRAS is an anti-Apoptotic protein. Ann N Y Acad Sci 2003;1009: 400-12
-
(2003)
Ann N y Acad Sci
, vol.1009
, pp. 400-412
-
-
Dontenwill, M.1
Piletz, J.E.2
Chen, M.3
Baldwin, J.4
Pascal, G.5
Ronde, P.6
|