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Volumn 28, Issue 11, 2008, Pages 3742-3756

Nischarin inhibits LIM kinase to regulate cofilin phosphorylation and cell invasion

Author keywords

[No Author keywords available]

Indexed keywords

COFILIN; LIM KINASE 1; NISCHARIN; P21 ACTIVATED KINASE; PDZ PROTEIN; PROTEIN; SMALL INTERFERING RNA; THREONINE;

EID: 44349130374     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01832-07     Document Type: Article
Times cited : (68)

References (63)
  • 1
    • 35649013184 scopus 로고    scopus 로고
    • MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3β
    • Abell, A. N., D. A. Granger, and G. L. Johnson. 2007. MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3β. J. Biol. Chem. 282:30476-30484.
    • (2007) J. Biol. Chem , vol.28 , Issue.2 , pp. 30476-30484
    • Abell, A.N.1    Granger, D.A.2    Johnson, G.L.3
  • 2
    • 33646926129 scopus 로고    scopus 로고
    • 14-3-3 proteins: A historic overview
    • Aitken, A. 2006. 14-3-3 proteins: a historic overview. Semin. Cancer Biol. 16:162-172.
    • (2006) Semin. Cancer Biol , vol.16 , pp. 162-172
    • Aitken, A.1
  • 3
    • 0042564472 scopus 로고    scopus 로고
    • Nischarin inhibits Rac induced migration and invasion of epithelial cells by affecting signaling cascades involving PAK
    • Alahari, S. K. 2003. Nischarin inhibits Rac induced migration and invasion of epithelial cells by affecting signaling cascades involving PAK. Exp. Cell Res. 288:415-424.
    • (2003) Exp. Cell Res , vol.288 , pp. 415-424
    • Alahari, S.K.1
  • 4
    • 0034638831 scopus 로고    scopus 로고
    • Nischarin, a novel protein that interacts with the integrin α5 subunit and inhibits cell migration
    • Alahari, S. K., J. W. Lee, and R. L. Juliano. 2000. Nischarin, a novel protein that interacts with the integrin α5 subunit and inhibits cell migration. J. Cell Biol. 151:1141-1154.
    • (2000) J. Cell Biol , vol.151 , pp. 1141-1154
    • Alahari, S.K.1    Lee, J.W.2    Juliano, R.L.3
  • 5
    • 0036377106 scopus 로고    scopus 로고
    • Biological aspects of signal transduction by cell adhesion receptors
    • Alahari, S. K., P. J. Reddig, and R. L. Juliano. 2002. Biological aspects of signal transduction by cell adhesion receptors. Int. Rev. Cytol. 220:145-184.
    • (2002) Int. Rev. Cytol , vol.220 , pp. 145-184
    • Alahari, S.K.1    Reddig, P.J.2    Juliano, R.L.3
  • 6
    • 3543034637 scopus 로고    scopus 로고
    • The integrin-binding protein Nischarin regulates cell migration by inhibiting PAK
    • Alahari, S. K., P. J. Reddig, and R. L. Juliano. 2004. The integrin-binding protein Nischarin regulates cell migration by inhibiting PAK. EMBO J. 23:2777-2788.
    • (2004) EMBO J , vol.23 , pp. 2777-2788
    • Alahari, S.K.1    Reddig, P.J.2    Juliano, R.L.3
  • 8
    • 33646376457 scopus 로고    scopus 로고
    • LIM kinase 1 increases tumor metastasis of human breast cancer cells via regulation of the urokinase-type plasminogen activator system
    • Bagheri-Yarmand, R., A. Mazumdar, A. A. Sahin, and R. Kumar. 2006. LIM kinase 1 increases tumor metastasis of human breast cancer cells via regulation of the urokinase-type plasminogen activator system. Int. J. Cancer 118:2703-2710.
    • (2006) Int. J. Cancer , vol.118 , pp. 2703-2710
    • Bagheri-Yarmand, R.1    Mazumdar, A.2    Sahin, A.A.3    Kumar, R.4
  • 10
    • 34249315804 scopus 로고    scopus 로고
    • Lim kinases, regulators of actin dynamics
    • Bernard, O. 2006. Lim kinases, regulators of actin dynamics. Int. J. Biochem. Cell. Biol. 39:1071-1076.
    • (2006) Int. J. Biochem. Cell. Biol , vol.39 , pp. 1071-1076
    • Bernard, O.1
  • 11
    • 0034213327 scopus 로고    scopus 로고
    • Rho GTPases and their effector proteins
    • Bishop, A. L., and A. Hall. 2000. Rho GTPases and their effector proteins. Biochem. J. 348:241-255.
    • (2000) Biochem. J , vol.348 , pp. 241-255
    • Bishop, A.L.1    Hall, A.2
  • 12
    • 0034614942 scopus 로고    scopus 로고
    • Role of cofilin in epidermal growth factor-stimulated actin polymerization and lamellipod protrusion
    • Chan, A. Y., M. Bailly, N. Zebda, J. E. Segall, and J. S. Condeelis. 2000. Role of cofilin in epidermal growth factor-stimulated actin polymerization and lamellipod protrusion. J. Cell Biol. 148:531-542.
    • (2000) J. Cell Biol , vol.148 , pp. 531-542
    • Chan, A.Y.1    Bailly, M.2    Zebda, N.3    Segall, J.E.4    Condeelis, J.S.5
  • 13
    • 33644530393 scopus 로고    scopus 로고
    • Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly
    • Chen, X., and I. G. Macara. 2006. Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly. J. Cell Biol. 172:671-678.
    • (2006) J. Cell Biol , vol.172 , pp. 671-678
    • Chen, X.1    Macara, I.G.2
  • 14
    • 0035943704 scopus 로고    scopus 로고
    • Cytoskeletal changes regulated by the Pak4 serine/threonine kinase are mediated by Lim kinase 1 and cofilin
    • Dan, C., A. Kelly, O. Bernard, and A. Minden. 2001. Cytoskeletal changes regulated by the Pak4 serine/threonine kinase are mediated by Lim kinase 1 and cofilin. J. Biol. Chem. 276:32115-32121.
    • (2001) J. Biol. Chem , vol.276 , pp. 32115-32121
    • Dan, C.1    Kelly, A.2    Bernard, O.3    Minden, A.4
  • 16
    • 0141480275 scopus 로고    scopus 로고
    • LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: Implications in prostate cancer
    • Davila, M., A. R. Frost, W. E. Grizzle, and R. Chakrabarti. 2003. LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: implications in prostate cancer. J. Biol. Chem. 278:36868-36875.
    • (2003) J. Biol. Chem , vol.278 , pp. 36868-36875
    • Davila, M.1    Frost, A.R.2    Grizzle, W.E.3    Chakrabarti, R.4
  • 18
    • 12244303674 scopus 로고    scopus 로고
    • ADF/cofilin controls cell polarity during fibroblast migration
    • Dawe, H. R., L. S. Minamide, J. R. Bamburg, and L. P. Cramer. 2003. ADF/cofilin controls cell polarity during fibroblast migration. Curr. Biol. 13:252-257.
    • (2003) Curr. Biol , vol.13 , pp. 252-257
    • Dawe, H.R.1    Minamide, L.S.2    Bamburg, J.R.3    Cramer, L.P.4
  • 20
    • 0033194037 scopus 로고    scopus 로고
    • Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics
    • Edwards, D. C., L. C. Sanders, G. M. Bokoch, and G. N. Gill. 1999. Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics. Nat. Cell Biol. 1:253-259.
    • (1999) Nat. Cell Biol , vol.1 , pp. 253-259
    • Edwards, D.C.1    Sanders, L.C.2    Bokoch, G.M.3    Gill, G.N.4
  • 22
    • 0037182585 scopus 로고    scopus 로고
    • LIM kinase and Diaphanous cooperate to regulate serum response factor and actin dynamics
    • Geneste, O., J. W. Copeland, and R. Treisman. 2002. LIM kinase and Diaphanous cooperate to regulate serum response factor and actin dynamics. J. Cell Biol. 157:831-838.
    • (2002) J. Cell Biol , vol.157 , pp. 831-838
    • Geneste, O.1    Copeland, J.W.2    Treisman, R.3
  • 23
    • 2342436150 scopus 로고    scopus 로고
    • Cofilin promotes actin polymerization and defines the direction of cell motility
    • Ghosh, M., X. Song, G. Mouneimne, M. Sidani, D. S. Lawrence, and J. S. Condeelis. 2004. Cofilin promotes actin polymerization and defines the direction of cell motility. Science 304:743-746.
    • (2004) Science , vol.304 , pp. 743-746
    • Ghosh, M.1    Song, X.2    Mouneimne, G.3    Sidani, M.4    Lawrence, D.S.5    Condeelis, J.S.6
  • 24
    • 33748757161 scopus 로고    scopus 로고
    • Phosphorylation- dependent regulation of unique nuclear and nucleolar localization signals of LIM kinase 2 in endothelial cells
    • Goyal, P., D. Pandey, and W. Siess. 2006. Phosphorylation- dependent regulation of unique nuclear and nucleolar localization signals of LIM kinase 2 in endothelial cells. J. Biol. Chem. 281:25223-25230.
    • (2006) J. Biol. Chem , vol.281 , pp. 25223-25230
    • Goyal, P.1    Pandey, D.2    Siess, W.3
  • 25
    • 33751252276 scopus 로고    scopus 로고
    • Cancer metastasis: Building a framework
    • Gupta, G. P., and J. Massague. 2006. Cancer metastasis: building a framework. Cell 127:679-695.
    • (2006) Cell , vol.127 , pp. 679-695
    • Gupta, G.P.1    Massague, J.2
  • 26
    • 0028225439 scopus 로고
    • Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins
    • Habets, G. G., E. H. Scholtes, D. Zuydgeest, R. A. van der Kammen, J. C. Stam, A. Berns, and J. G. Collard. 1994. Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins. Cell 77:537-549.
    • (1994) Cell , vol.77 , pp. 537-549
    • Habets, G.G.1    Scholtes, E.H.2    Zuydgeest, D.3    van der Kammen, R.A.4    Stam, J.C.5    Berns, A.6    Collard, J.G.7
  • 27
    • 27844604200 scopus 로고    scopus 로고
    • Rho GTPases and the control of cell behaviour
    • Hall, A. 2005. Rho GTPases and the control of cell behaviour. Biochem. Soc. Trans. 33:891-895.
    • (2005) Biochem. Soc. Trans , vol.33 , pp. 891-895
    • Hall, A.1
  • 28
    • 12844269159 scopus 로고    scopus 로고
    • Actin-depolymerizfng factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells
    • Hotulainen, P., E. Paunola, M. K. Vartiainen, and P. Lappalainen. 2005. Actin-depolymerizfng factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells. Mol. Biol. Cell 16:649-664.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 649-664
    • Hotulainen, P.1    Paunola, E.2    Vartiainen, M.K.3    Lappalainen, P.4
  • 29
    • 0035944830 scopus 로고    scopus 로고
    • Rho GTPases as early markers for tumour progression
    • Keely, P. J. 2001. Rho GTPases as early markers for tumour progression. Lancet 358:1744-1745.
    • (2001) Lancet , vol.358 , pp. 1744-1745
    • Keely, P.J.1
  • 33
    • 11144228295 scopus 로고    scopus 로고
    • Human nischarin/imidazoline receptor antisera-selectcd protein is targeted to the endosomes by a combined action of a PX domain and a coiled-coil region
    • Lim, K. P., and W. Hong. 2004. Human nischarin/imidazoline receptor antisera-selectcd protein is targeted to the endosomes by a combined action of a PX domain and a coiled-coil region. J. Biol. Chem. 279:54770-54782.
    • (2004) J. Biol. Chem , vol.279 , pp. 54770-54782
    • Lim, K.P.1    Hong, W.2
  • 35
    • 0035503218 scopus 로고    scopus 로고
    • Dok-R plays a pivotal role in angiopoietin-1-dependent cell migration through recruitment and activation of Pak
    • Master, Z., N. Jones, J. Tran, J. Jones, R. S. Kerbel, and D. J. Dumont. 2001. Dok-R plays a pivotal role in angiopoietin-1-dependent cell migration through recruitment and activation of Pak. EMBO J. 20:5919-5928.
    • (2001) EMBO J , vol.20 , pp. 5919-5928
    • Master, Z.1    Jones, N.2    Tran, J.3    Jones, J.4    Kerbel, R.S.5    Dumont, D.J.6
  • 36
    • 0030049170 scopus 로고    scopus 로고
    • Actin-based cell motility and cell locomotion
    • Mitchison, T. J., and L. P. Cramer. 1996. Actin-based cell motility and cell locomotion. Cell 84:371-379.
    • (1996) Cell , vol.84 , pp. 371-379
    • Mitchison, T.J.1    Cramer, L.P.2
  • 38
    • 27544502276 scopus 로고    scopus 로고
    • Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration
    • Nishita, M., C. Tomizawa, M. Yamamoto, Y. Horita, K. Ohashi, and K. Mizuno. 2005. Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration. J. Cell Biol. 171:349-359.
    • (2005) J. Cell Biol , vol.171 , pp. 349-359
    • Nishita, M.1    Tomizawa, C.2    Yamamoto, M.3    Horita, Y.4    Ohashi, K.5    Mizuno, K.6
  • 39
    • 0037169335 scopus 로고    scopus 로고
    • Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin
    • Niwa, R., K. Nagata-Ohashi, M. Takeichi, K. Mizuno, and T. Uemura. 2002. Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin. Cell 108:233-246.
    • (2002) Cell , vol.108 , pp. 233-246
    • Niwa, R.1    Nagata-Ohashi, K.2    Takeichi, M.3    Mizuno, K.4    Uemura, T.5
  • 40
    • 28244469687 scopus 로고    scopus 로고
    • The neurofibromatosis type 1 gene product neurofibromin enhances cell motility by regulating actin filament dynamics via the Rho-ROCK-LIMK2-cofilin pathway
    • Ozawa, T., N. Araki, S. Yunoue, H. Tokuo, L. Feng, S. Patrakitkomjorn, T. Hara, Y. Ichikawa, K. Matsumoto, K. Fujii, and H. Saya. 2005. The neurofibromatosis type 1 gene product neurofibromin enhances cell motility by regulating actin filament dynamics via the Rho-ROCK-LIMK2-cofilin pathway. J. Biol. Chem. 280:39524-39533.
    • (2005) J. Biol. Chem , vol.280 , pp. 39524-39533
    • Ozawa, T.1    Araki, N.2    Yunoue, S.3    Tokuo, H.4    Feng, L.5    Patrakitkomjorn, S.6    Hara, T.7    Ichikawa, Y.8    Matsumoto, K.9    Fujii, K.10    Saya, H.11
  • 41
    • 30444460134 scopus 로고    scopus 로고
    • Regulation of LIM-kinase 1 and cofilin in thrombin-stimulated platelets
    • Pandey, D., P. Goyal, J. R. Bamburg, and W. Siess. 2006. Regulation of LIM-kinase 1 and cofilin in thrombin-stimulated platelets. Blood 107:575-583.
    • (2006) Blood , vol.107 , pp. 575-583
    • Pandey, D.1    Goyal, P.2    Bamburg, J.R.3    Siess, W.4
  • 42
    • 0037459075 scopus 로고    scopus 로고
    • Cellular motility driven by assembly and disassembly of actin filaments
    • Pollard, T. D., and G. G. Borisy. 2003. Cellular motility driven by assembly and disassembly of actin filaments. Cell 112:453-465.
    • (2003) Cell , vol.112 , pp. 453-465
    • Pollard, T.D.1    Borisy, G.G.2
  • 43
    • 24744462314 scopus 로고    scopus 로고
    • Regulation of p21-activated kinase-independent Rac1 signal transduction by nischarin
    • Reddig, P. J., D. Xu, and R. L. Juliano. 2005. Regulation of p21-activated kinase-independent Rac1 signal transduction by nischarin. J. Biol. Chem. 280:30994-31002.
    • (2005) J. Biol. Chem , vol.280 , pp. 30994-31002
    • Reddig, P.J.1    Xu, D.2    Juliano, R.L.3
  • 44
  • 45
    • 17144377069 scopus 로고    scopus 로고
    • RhoE function is regulated by ROCK I-mediated phosphorylation
    • Riento, K., N. Totty, P. Villalonga, R. Garg, R. Guasch, and A. J. Ridley. 2005. RhoE function is regulated by ROCK I-mediated phosphorylation. EMBO J. 24:1170-1180.
    • (2005) EMBO J , vol.24 , pp. 1170-1180
    • Riento, K.1    Totty, N.2    Villalonga, P.3    Garg, R.4    Guasch, R.5    Ridley, A.J.6
  • 47
    • 0033842959 scopus 로고    scopus 로고
    • Molecular signaling mechanisms of cell migration and invasion
    • Stupack, D. G., S. Y. Cho, and R. L. Klemke. 2000. Molecular signaling mechanisms of cell migration and invasion. Immunol. Res. 21:83-88.
    • (2000) Immunol. Res , vol.21 , pp. 83-88
    • Stupack, D.G.1    Cho, S.Y.2    Klemke, R.L.3
  • 49
    • 33750289641 scopus 로고    scopus 로고
    • ROCK signaling mediates the adoption of different modes of migration and invasion in human mammary epithelial tumor cells
    • Torka, R., F. Thuma, V. Herzog, and G. Kirfel. 2006. ROCK signaling mediates the adoption of different modes of migration and invasion in human mammary epithelial tumor cells. Exp. Cell Res. 312:3857-3871.
    • (2006) Exp. Cell Res , vol.312 , pp. 3857-3871
    • Torka, R.1    Thuma, F.2    Herzog, V.3    Kirfel, G.4
  • 50
    • 0035171699 scopus 로고    scopus 로고
    • Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation
    • Toshima, J., J. Y. Toshima, T. Amano, N. Yang, S. Narumiya, and K. Mizuno. 2001. Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation. Mol. Biol. Cell 12:1131-1145.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 1131-1145
    • Toshima, J.1    Toshima, J.Y.2    Amano, T.3    Yang, N.4    Narumiya, S.5    Mizuno, K.6
  • 51
    • 0032493746 scopus 로고    scopus 로고
    • Transmembrane neuregulins interact with LIM kinase 1, a cytoplasmic protein kinase implicated in development of visuospatial cognition
    • Wang, J. Y., K. E. Frenzel, D. Wen, and D. L. Falls. 1998. Transmembrane neuregulins interact with LIM kinase 1, a cytoplasmic protein kinase implicated in development of visuospatial cognition. J. Biol. Chem. 273:20525-20534.
    • (1998) J. Biol. Chem , vol.273 , pp. 20525-20534
    • Wang, J.Y.1    Frenzel, K.E.2    Wen, D.3    Falls, D.L.4
  • 52
    • 34249281332 scopus 로고    scopus 로고
    • The cofilin pathway in breast cancer invasion and metastasis
    • Wang, W., R. Eddy, and J. Condeelis. 2007. The cofilin pathway in breast cancer invasion and metastasis. Nat. Rev. Cancer 7:429-440.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 429-440
    • Wang, W.1    Eddy, R.2    Condeelis, J.3
  • 54
    • 26444492532 scopus 로고    scopus 로고
    • Cancer invasion and metastasis
    • Wittekind, C., and M. Neid. 2005. Cancer invasion and metastasis. Oncology 69:14-16.
    • (2005) Oncology , vol.69 , pp. 14-16
    • Wittekind, C.1    Neid, M.2
  • 55
    • 34247468876 scopus 로고    scopus 로고
    • Regulation of the actin cytoskeleton in cancer cell migration and invasion
    • Yamaguchi, H., and J. Condeelis. 2006. Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim. Biophys. Acta 1773:642-652.
    • (2006) Biochim. Biophys. Acta , vol.1773 , pp. 642-652
    • Yamaguchi, H.1    Condeelis, J.2
  • 58
    • 23844488162 scopus 로고    scopus 로고
    • Regulation of cancer cell motility through actin reorganization
    • Yamazaki, D., S. Kurisu, and T. Takenawa. 2005. Regulation of cancer cell motility through actin reorganization. Cancer Sci. 96:379-386.
    • (2005) Cancer Sci , vol.96 , pp. 379-386
    • Yamazaki, D.1    Kurisu, S.2    Takenawa, T.3
  • 59
    • 0032565769 scopus 로고    scopus 로고
    • Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization
    • Yang, N., O. Higuchi, K. Ohashi, K. Nagata, A. Wada, K. Kangawa, E. Nishida, and K. Mizuno. 1998. Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Nature 393:809-812.
    • (1998) Nature , vol.393 , pp. 809-812
    • Yang, N.1    Higuchi, O.2    Ohashi, K.3    Nagata, K.4    Wada, A.5    Kangawa, K.6    Nishida, E.7    Mizuno, K.8
  • 62
    • 37349035623 scopus 로고    scopus 로고
    • Inhibition of nischarin expression attenuates rilmenidine-evoked hypotension and phosphorylated extracellular signal-regulated kinase 1/2 production in the rostral ventrolateral medulla of rats
    • Zhang, J., and A. A. Abdel-Rahman. 2008. Inhibition of nischarin expression attenuates rilmenidine-evoked hypotension and phosphorylated extracellular signal-regulated kinase 1/2 production in the rostral ventrolateral medulla of rats. J. Pharmacol. Exp. Ther. 324:72-78.
    • (2008) J. Pharmacol. Exp. Ther , vol.324 , pp. 72-78
    • Zhang, J.1    Abdel-Rahman, A.A.2
  • 63
    • 26944442735 scopus 로고    scopus 로고
    • The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A
    • Zhao, Z. S., J. P. Lim, Y. W. Ng, L. Lim, and E. Manser. 2005. The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A. Mol. Cell 20:237-249.
    • (2005) Mol. Cell , vol.20 , pp. 237-249
    • Zhao, Z.S.1    Lim, J.P.2    Ng, Y.W.3    Lim, L.4    Manser, E.5


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