Possible herb-drug interaction of Morus alba L.- a potential anti-diabetic plant from Indian traditional medicine

Indian Journal of Traditional Knowledge

Volumn 14, Issue 4, 2015, Pages 626-631

  Kar, Amit ^a   Mukherjee, Pulok K ^a   Saha, Sankarshan ^a   Bahadur, Shiv ^a   Ahmmed, S K Milan ^a   Pandit, Subrata ^a  

^a JADAVPUR UNIVERSITY   (India)

Author keywords

Anti diabetic; Cytochrome P450; Herb drug interaction; Medicinal plant; Rp Hplc

Indexed keywords

EID: 84945355365     PISSN: 09725938     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Kim H, Choi HK, Jeong TC, Jahng Y & Kim DH, et al., Selective inhibitory effects of mollugin on CYP1A2 in human liver microsomes, Food chem Toxicol, 51 (2013) 33-37.
2. Pandit S, Mukherjee PK, Mukherjee K, Gajbhiye R & Venkatesh M, et al., Cytochrome P450 inhibitory potential of selected Indian spices — possible food drug interaction, Food Res Int, 45 (2012) 69-74.
3. Choi EJ, Park JB, Yoon KD & Bae SK, Evaluation of the in vitro/in vivo potential of five berries (bilberry, blueberry, cranberry, elderberry, and raspberry ketones) commonly used as herbal supplements to inhibit uridine diphosphoglucuronosyltransferase, Food Chem Toxicol, 72 (2014) 13–19.
4. Mukherjee PK, Ponnusankar S, Pandit S, Hazam PK & Ahmmed M, et al., Botanicals as medicinal food and their effects on drug metabolizing enzymes, Food Chem Toxicol, 49 (12) (2011) 3142-3153.
5. Mukherjee PK, Nema NK, Venkatesh P & Debnath PK, Changing scenario for promotion and development of ayurvedaway forward, J Ethnopharmacol, 143 (2012) 424–434.
6. Pekthong D, Martin H, Abadie C, Bonet A, et al., Differential inhibition of rat and human hepatic cytochrome P450 by Andrographis paniculata extract and andrographolide, J Ethnopharmacol, 115 (2012) 432-440.
7. Strandell J Neil & Carlin G, An approach to the in vitro evaluation of potential for Cytochrome P450 enzyme inhibition from herbals and other natural remedies, Phytomedicine, 11 (2012) 98–104.
8. Mukherjee PK, Quality control of herbal drugs-an approach to evaluation of Botanicals, edited by Mukherjee PK, (Business Horizon, New Delhi), 2002, 246.
9. Houghton P & Mukherjee PK, Evaluation of herbal medicinal products. In Evaluation of quality and safety edited by Houghton P & Mukherjee PK, (Pharmaceutical Press, London) 2009, 395-425.
10. Mukherjee PK, Bahadur S, Chaudhary SK, Kar A & Mukherjee K, Quality Related Safety Issue-Evidence-Based Validation of Herbal Medicine Farm to Pharma In Evidence based validation of herbal medicine, edited by Mukherjee PK, (Elsevier Science, Netherlands, USA) 2015, 1-28.
11. Wang Y, Xiang L, Wang C, Tang C & He X, Antidiabetic and Antioxidant Effects and Phytochemicals of Mulberry Fruit (Morus alba L.) Polyphenol Enhanced Extract, PLos One, 8(7) (2013) e71144. doi:10.1371/journal.pone.0071144.
12. Piao SJ, Chen LX, Kang N & Qiu F, Simultaneous determination of five characteristic stilbene glycosides in root bark of Morus albus L. (Cortex Mori) using highperformance liquid chromatography, Phytochem Anal, 22(3) (2011) 230–5.
13. Lee YJ, Choi DH, Kim EJ, Kim HY, Kwon TO, et al., Hypotensive, hypolipidemic, and vascular protective effects of Morus alba L. in rats fed an atherogenic diet, Am J Chin Med, 39(1) (2011) 39–52.
14. Ameen AM, Hapipah MA, Abdul AK, Mohd NS & Salmah I, Evaluation of the antiulcer activities of Morus alba extracts in experimentally induced gastric ulcer in rats, Biomed Res, 20(1) (2009) 35-9.
15. Hunyadi A, Martins A, Hsieh TJ, Seres A & Zupk� I, Chlorogenic acid and rutin play a major role in the in vivo anti-diabetic activity of Morus alba leaf extract on type II diabetic rats, PLos One, 7(11) (2012) e50619 doi: 10.1371/journal.pone.0050619.
16. Kim HG, Ju MS, Shim JS, Kim MC & Lee SH, et al., Mulberry fruit protects dopaminergic neurons in toxin-induced Parkinson's disease models, Br J Nutr, 104 (2010) 8-16.
17. Choi EM & Hwang JK, Effects of Morus alba leaf extract on the production of nitric oxide prostaglandin E2 and cytokines in RAW2647 macrophages, Fitoterapia, 76 (7–8) (2005) 608–613.
18. Ponnusankar S, Pandit S, Venkatesh M, Bandyopadhyay A & Mukherjee PK, Cytochrome P450 Inhibition Assay for Standardized Extract of Terminalia chebula Retz, Phytother Res, 25 (2011) 151–154.
19. Pandit S, Mukherjee PK, Ponnusankar S, Venkatesh M & Srikanth N, Metabolism mediated interaction of α-asarone and Acorus calamus with CYP3A4 and CYP2D6, Fitoterapia, 82(3) (2011) 369-374.
20. Choi SJ, Kim M, Kim SI & Jeon JK, Microplate assay measurement of cytochrome P450-carbon monoxide complexes, J Biochem Molbiol, 36 (2003) 332–335.
21. Harwansh RK, Mukherjee K, Bhadra S, Kar A, Bahadur S, Mitra A & Mukherjee PK, Cytochrome P450 inhibitory potential and RP-HPLC standardization of Trikatu – A Rasayana from Indian Ayurveda, J Ethnopharmacol, 153 (2014) 674–681.