BC3EE2,9B, a synthetic carbazole derivative, upregulates autophagy and synergistically sensitizes human GBM8901 glioblastoma cells to temozolomide

International Journal of Molecular Medicine

Volumn 36, Issue 5, 2015, Pages 1244-1252

  Chen, Chien Min ^a,b,f   Syu, Jhih Pu ^c   Way, Tzong Der ^d   Huang, Li Jiau ^d   Kuo, Sheng Chu ^d   Lin, Chung Tien ^a   Lin, Chih Li ^c,e  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

^e CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^f KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Akt; Autophagy; Carbazole; Glioblastoma; Temozolomide

Indexed keywords

ANTINEOPLASTIC AGENT; BC 3EE 29B; CARBAZOLE DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; TEMOZOLOMIDE; UNCLASSIFIED DRUG; CARBAZOLE; DACARBAZINE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; AUTOPHAGY; CANCER INHIBITION; CHEMOSENSITIZATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVATION; G1 PHASE CELL CYCLE CHECKPOINT; GLIOBLASTOMA; GLIOBLASTOMA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; METASTASIS INHIBITION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR INVASION; UPREGULATION; ANALOGS AND DERIVATIVES; BRAIN NEOPLASMS; CELL CYCLE CHECKPOINT; CELL CYCLE G1 PHASE; CELL MOTION; CELL PROLIFERATION; DRUG EFFECTS; DRUG RESISTANCE; GENETICS; PATHOLOGY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; AUTOPHAGY; BRAIN NEOPLASMS; CARBAZOLES; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DACARBAZINE; DRUG RESISTANCE, NEOPLASM; DRUG SYNERGISM; G1 PHASE; GLIOBLASTOMA; HUMANS; NEOPLASM INVASIVENESS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84945340336     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2015.2332     Document Type: Article

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