Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds

Journal of Controlled Release

Volumn 220, Issue , 2015, Pages 79-88

  Freudenberg, Uwe ^a   Zieris, Andrea ^a   Chwalek, Karolina ^a   Tsurkan, Mikhail V ^a   Maitz, Manfred F ^a   Atallah, Passant ^a   Levental, Kandice R ^a   Eming, Sabine A ^b   Werner, Carsten ^a  

^a CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Angiogenesis; Glycosaminoglycans; Growth factors; Heparin; Hydrogels; VEGF

Indexed keywords

COMPLEXATION; DRUG PRODUCTS; ENDOTHELIAL CELLS; POLYETHYLENE GLYCOLS; POLYSACCHARIDES;

ANGIOGENESIS; GLYCOSAMINOGLYCANS; GROWTH FACTOR; HEPARIN; VEGF;

HYDROGELS;

HEPARIN; MACROGOL; SULFATE; VASCULOTROPIN; GLYCOSAMINOGLYCAN; HYDROGEL; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICOAGULATION; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DRUG SULFATION; EXPERIMENTAL DIABETES MELLITUS; HUMAN; HUMAN CELL; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SECRETION; UMBILICAL VEIN ENDOTHELIAL CELL; WOUND HEALING; ANIMAL; CELL CULTURE; CHEMISTRY; DIABETES COMPLICATIONS; DIABETES MELLITUS; DRUG EFFECTS; PATHOPHYSIOLOGY; SECRETION (PROCESS);

ANIMALS; CELLS, CULTURED; DIABETES COMPLICATIONS; DIABETES MELLITUS; GLYCOSAMINOGLYCANS; HEPARIN; HUMANS; HYDROGELS; MALE; MICE; NEOVASCULARIZATION, PHYSIOLOGIC; SULFATES; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

EID: 84945276142     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.10.028     Document Type: Article

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