Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth

Developmental Cell

Volumn 35, Issue 1, 2015, Pages 21-35

  D'Amico, Davide ^a   Antonucci, Laura ^a,b   Di Magno, Laura ^b   Coni, Sonia ^a   Sdruscia, Giulia ^b   Macone, Alberto ^b   Miele, Evelina ^b   Infante, Paola ^b   Di Marcotullio, Lucia ^a,b   De Smaele, Enrico ^b   Ferretti, Elisabetta ^b   Ciapponi, Laura ^b   Giangaspero, Felice ^b   Yates, John R ^d   Agostinelli, Enzo ^b   Cardinali, Beatrice ^c   Screpanti, Isabella ^a,b   Gulino, Alberto ^a,b   Canettieri, Gianluca ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c CNR   (Italy)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; ANTINEOPLASTIC AGENT; CELL PROTEIN; DIFLUOROMETHYLORNITINE; ORNITHINE DECARBOXYLASE; POLYAMINE; PUTRESCINE; SONIC HEDGEHOG PROTEIN; SPERMIDINE; SPERMINE; SUFU PROTEIN; THREONINE; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN CNBP; CNBP PROTEIN, HUMAN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; REPRESSOR PROTEIN; RNA BINDING PROTEIN; SUFU PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CANCER GROWTH; CANCER INHIBITION; CELL PROLIFERATION; CELL PROLIFERATION INHIBITION; CEREBELLAR GRANULE CELL PRECURSOR; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME SYNTHESIS; FEMALE; GRANULE CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MEDULLOBLASTOMA; METABOLIC REGULATION; MOUSE; NERVE CELL GROWTH; NONHUMAN; POLYAMINE METABOLISM; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STEM CELL; TRANSLATION REGULATION; 3T3 CELL LINE; ANIMAL; APOPTOSIS; CELL CULTURE; CEREBELLUM TUMOR; CYTOLOGY; DRUG SCREENING; FIBROBLAST; GENETICS; HEK293 CELL LINE; IMMUNOPRECIPITATION; MAMMALIAN EMBRYO; METABOLISM; NERVE CELL; NUDE MOUSE; PATHOLOGY; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; CEREBELLAR NEOPLASMS; EMBRYO, MAMMALIAN; FEMALE; FIBROBLASTS; HEDGEHOG PROTEINS; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; MEDULLOBLASTOMA; MICE; MICE, NUDE; NEURONS; NIH 3T3 CELLS; ORNITHINE DECARBOXYLASE; PHOSPHORYLATION; POLYAMINES; REAL-TIME POLYMERASE CHAIN REACTION; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA-BINDING PROTEINS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84945252145     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2015.09.008     Document Type: Article

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