Design and activity of a cyclic mini-β-defensin analog: A novel antimicrobial tool

International Journal of Nanomedicine

Volumn 10, Issue , 2015, Pages 6523-6539

  Scudiero, Olga ^a,b   Nigro, Ersilia ^a   Cantisani, Marco ^b   Colavita, Irene ^a   Leone, Marilisa ^c   Mercurio, Flavia Anna ^c   Galdiero, Massimiliano ^d   Pessi, Antonello ^a   Daniele, Aurora ^a,d   Salvatore, Francesco ^a,b,e   Galdiero, Stefania ^b,c  

^a CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c CNR   (Italy)

^d SECOND UNIVERSITY OF NAPLES   (Italy)

^e IRCCS SDN   (Italy)

Author keywords

Antimicrobial activity; Cyclic mini peptide; Human beta defensin

Indexed keywords

ANTIMICROBIAL CYCLIC PEPTIDE; BETA DEFENSIN 1; BETA DEFENSIN 3; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; ANTIVIRUS AGENT; BETA DEFENSIN; DISULFIDE;

ANTIMICROBIAL ACTIVITY; ANTIVIRAL ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DISULFIDE BOND; DOSE RESPONSE; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENCAPSULATION; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IN VITRO STUDY; NANOMEDICINE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PSEUDOMONAS AERUGINOSA; AMINO ACID SEQUENCE; BACTERIUM; CACO-2 CELL LINE; CHEMISTRY; DRUG EFFECTS; DRUG STABILITY; MOLECULAR GENETICS;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; ANTIVIRAL AGENTS; BACTERIA; BETA-DEFENSINS; CACO-2 CELLS; DISULFIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; DRUG STABILITY; HERPESVIRUS 1, HUMAN; HUMANS; MOLECULAR SEQUENCE DATA;

EID: 84945208886     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S89610     Document Type: Article

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