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Volumn 89, Issue 21, 2015, Pages 11011-11018

Bst2/tetherin is induced in neurons by type I interferon and viral infection but is dispensable for protection against neurotropic viral challenge

Author keywords

[No Author keywords available]

Indexed keywords

BST2 PROTEIN; INTERFERON; MEMBRANE PROTEIN; RNA; STAT1 PROTEIN; UNCLASSIFIED DRUG; BST2 PROTEIN, MOUSE; LEUKOCYTE ANTIGEN; PRIMER DNA;

EID: 84945207996     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01745-15     Document Type: Article
Times cited : (22)

References (47)
  • 1
    • 0033795196 scopus 로고    scopus 로고
    • Interferons: cell signalling, immune modulation, antiviral responses and virus countermea- sures
    • Goodbourn S, Didcock L, Randall RE. 2000. Interferons: cell signalling, immune modulation, antiviral responses and virus countermea- sures. J Gen Virol 81:2341-2364. http://dx.doi.org/10.1099/0022-1317 -81-10-2341.
    • (2000) J Gen Virol , vol.81 , pp. 2341-2364
    • Goodbourn, S.1    Didcock, L.2    Randall, R.E.3
  • 2
    • 84875336930 scopus 로고    scopus 로고
    • Antiviral type I and type III interferon responses in the central nervous system
    • Sorgeloos F, Kreit M, Hermant P, Lardinois C, Michiels T. 2013. Antiviral type I and type III interferon responses in the central nervous system. Viruses 5:834-857. http://dx.doi.org/10.3390/v5030834.
    • (2013) Viruses , vol.5 , pp. 834-857
    • Sorgeloos, F.1    Kreit, M.2    Hermant, P.3    Lardinois, C.4    Michiels, T.5
  • 3
    • 84924584546 scopus 로고    scopus 로고
    • New insights into type I interferon and the immunopathogenesis of persistent viral infections
    • Snell LM, Brooks DG. 2015. New insights into type I interferon and the immunopathogenesis of persistent viral infections. Curr Opin Immunol 34:91-98. http://dx.doi.org/10.1016/j.coi.2015.03.002.
    • (2015) Curr Opin Immunol , vol.34 , pp. 91-98
    • Snell, L.M.1    Brooks, D.G.2
  • 4
    • 33747803946 scopus 로고    scopus 로고
    • Bone marrow stromal cell antigen 2 is a specific marker of type I IFN-producing cells in the naive mouse, but a promiscuous cell surface antigen following IFN stimulation
    • Blasius AL, Giurisato E, Cella M, Schreiber RD, Shaw AS, Colonna M. 2006. Bone marrow stromal cell antigen 2 is a specific marker of type I IFN-producing cells in the naive mouse, but a promiscuous cell surface antigen following IFN stimulation. J Immunol 177:3260-3265. http://dx .doi.org/10.4049/jimmunol.177.5.3260.
    • (2006) J Immunol , vol.177 , pp. 3260-3265
    • Blasius, A.L.1    Giurisato, E.2    Cella, M.3    Schreiber, R.D.4    Shaw, A.S.5    Colonna, M.6
  • 5
    • 0028101333 scopus 로고
    • A novel membrane antigen selectively expressed on terminally differentiated human B cells
    • Goto T, Kennel SJ, Abe M, Takishita M, Kosaka M, Solomon A, Saito S. 1994. A novel membrane antigen selectively expressed on terminally differentiated human B cells. Blood 84:1922-1930.
    • (1994) Blood , vol.84 , pp. 1922-1930
    • Goto, T.1    Kennel, S.J.2    Abe, M.3    Takishita, M.4    Kosaka, M.5    Solomon, A.6    Saito, S.7
  • 6
    • 38549095979 scopus 로고    scopus 로고
    • Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu
    • Neil SJD, Zang T, Bieniasz PD. 2008. Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu. Nature 451:425-430. http://dx.doi.org /10.1038/nature06553.
    • (2008) Nature , vol.451 , pp. 425-430
    • Neil, S.J.D.1    Zang, T.2    Bieniasz, P.D.3
  • 7
    • 77950424913 scopus 로고    scopus 로고
    • Direct restriction of virus release and incorporation of the interferon- induced protein BST-2 into HIV-1 particles
    • Fitzpatrick K, Skasko M, Deerinck TJ, Crum J, Ellisman MH, Guatelli J. 2010. Direct restriction of virus release and incorporation of the interferon- induced protein BST-2 into HIV-1 particles. PLoS Pathog 6(3): e1000701. http://dx.doi.org/10.1371/journal.ppat.1000701.
    • (2010) PLoS Pathog. , vol.6 , Issue.3 , pp. e1000701
    • Fitzpatrick, K.1    Skasko, M.2    Deerinck, T.J.3    Crum, J.4    Ellisman, M.H.5    Guatelli, J.6
  • 9
    • 41849116366 scopus 로고    scopus 로고
    • The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein
    • Van Damme N, Goff D, Katsura C, Jorgenson RL, Mitchell R, Johnson MC, Stephens EB, Guatelli J. 2008. The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein. Cell Host Microbe 3:245-252. http://dx.doi.org /10.1016/j.chom.2008.03.001.
    • (2008) Cell Host Microbe , vol.3 , pp. 245-252
    • Van Damme, N.1    Goff, D.2    Katsura, C.3    Jorgenson, R.L.4    Mitchell, R.5    Johnson, M.C.6    Stephens, E.B.7    Guatelli, J.8
  • 10
    • 77649251047 scopus 로고    scopus 로고
    • Immunoelectron microscopic evidence for tetherin/BST2 as the physical bridge between HIV-1 virions and the plasma membrane
    • Hammonds J, Wang J-J, Yi H, Spearman P. 2010. Immunoelectron microscopic evidence for tetherin/BST2 as the physical bridge between HIV-1 virions and the plasma membrane. PLoS Pathog 6(2):e1000749. http://dx.doi.org/10.1371/journal.ppat.1000749.
    • (2010) PLoS Pathog. , vol.6 , Issue.2 , pp. e1000749
    • Hammonds, J.1    Wang, J.-J.2    Yi, H.3    Spearman, P.4
  • 11
    • 62449106199 scopus 로고    scopus 로고
    • Tetherinmediated restriction of filovirus budding is antagonized by the Ebola glycoprotein
    • Kaletsky RL, Francica JR, Agrawal-Gamse C, Bates P. 2009. Tetherinmediated restriction of filovirus budding is antagonized by the Ebola glycoprotein. Proc Natl Acad Sci U S A 106:2886-2891. http://dx.doi.org/10 .1073/pnas.0811014106.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 2886-2891
    • Kaletsky, R.L.1    Francica, J.R.2    Agrawal-Gamse, C.3    Bates, P.4
  • 12
    • 78649404289 scopus 로고    scopus 로고
    • Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms
    • Weidner JM, Jiang D, Pan XB, Chang J, Block TM, Guo JT. 2010. Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms. J Virol 84: 12646-12657. http://dx.doi.org/10.1128/JVI.01328-10.
    • (2010) J Virol , vol.84 , pp. 12646-12657
    • Weidner, J.M.1    Jiang, D.2    Pan, X.B.3    Chang, J.4    Block, T.M.5    Guo, J.T.6
  • 13
    • 84911928004 scopus 로고    scopus 로고
    • Tetherin restricts HSV-2 release and is counteracted by multiple viral glycoproteins
    • Liu Y, Luo S, He S, Zhang M, Wang P, Li C, Huang W, Hu B, Griffin GE, Shattock RJ. 2015. Tetherin restricts HSV-2 release and is counteracted by multiple viral glycoproteins. Virology 475:96-109. http://dx.doi .org/10.1016/j.virol.2014.11.005.
    • (2015) Virology , vol.475 , pp. 96-109
    • Liu, Y.1    Luo, S.2    He, S.3    Zhang, M.4    Wang, P.5    Li, C.6    Huang, W.7    Hu, B.8    Griffin, G.E.9    Shattock, R.J.10
  • 14
    • 84887989681 scopus 로고    scopus 로고
    • Emerging role of the host restriction factor tetherin in viral immune sensing
    • Hotter D, Sauter D, Kirchhoff F. 2013. Emerging role of the host restriction factor tetherin in viral immune sensing. J Mol Biol 425:4956-4964. http://dx.doi.org/10.1016/j.jmb.2013.09.029.
    • (2013) J Mol Biol , vol.425 , pp. 4956-4964
    • Hotter, D.1    Sauter, D.2    Kirchhoff, F.3
  • 15
    • 79959211941 scopus 로고    scopus 로고
    • Host factors involved in retroviral budding and release
    • Martin-Serrano J, Neil SJD. 2011. Host factors involved in retroviral budding and release. Nat Rev Microbiol 9:519-531. http://dx.doi.org/10 .1038/nrmicro2596.
    • (2011) Nat Rev Microbiol , vol.9 , pp. 519-531
    • Martin-Serrano, J.1    Neil, S.J.D.2
  • 16
    • 77956188831 scopus 로고    scopus 로고
    • BST-2/ tetherin: a new component of the innate immune response to enveloped viruses
    • Evans DT, Serra-Moreno R, Singh RK, Guatelli JC. 2010. BST-2/ tetherin: a new component of the innate immune response to enveloped viruses. Trends Microbiol 18:388-396. http://dx.doi.org/10.1016/j.tim .2010.06.010.
    • (2010) Trends Microbiol , vol.18 , pp. 388-396
    • Evans, D.T.1    Serra-Moreno, R.2    Singh, R.K.3    Guatelli, J.C.4
  • 17
    • 84866925345 scopus 로고    scopus 로고
    • Identification of alternatively translated tetherin isoforms with differing antiviral and signaling activities
    • Cocka LJ, Bates P. 2012. Identification of alternatively translated tetherin isoforms with differing antiviral and signaling activities. PLoS Pathog 8(9):e1002931. http://dx.doi.org/10.1371/journal.ppat.1002931.
    • (2012) PLoS Pathog. , vol.8 , Issue.9 , pp. e1002931
    • Cocka, L.J.1    Bates, P.2
  • 18
    • 84899819636 scopus 로고    scopus 로고
    • Transmembrane helices are represented by cylinders and the Nef myristoyl anchor is represented by a cyan sphere
    • Jia X, Weber E, Tokarev A, Lewinski M, Rizk M, Suarez M, Guatelli J, Xiong Y. 2014. Transmembrane helices are represented by cylinders and the Nef myristoyl anchor is represented by a cyan sphere. Elife 3:1-24. http://dx.doi.org/10.7554/eLife.02362.
    • (2014) Elife , vol.3 , pp. 1-24
    • Jia, X.1    Weber, E.2    Tokarev, A.3    Lewinski, M.4    Rizk, M.5    Suarez, M.6    Guatelli, J.7    Xiong, Y.8
  • 19
    • 84884769542 scopus 로고    scopus 로고
    • Tetherin/ BST-2 antagonism by Nef depends on a direct physical interaction between Nef and tetherin, and on clathrin-mediated endocytosis
    • Serra-Moreno R, Zimmermann K, Stern LJ, Evans DT. 2013. Tetherin/ BST-2 antagonism by Nef depends on a direct physical interaction between Nef and tetherin, and on clathrin-mediated endocytosis. PLoS Pathog 9(7):e1003487. http://dx.doi.org/10.1371/journal.ppat.1003487.
    • (2013) PLoS Pathog. , vol.9 , Issue.7 , pp. e1003487
    • Serra-Moreno, R.1    Zimmermann, K.2    Stern, L.J.3    Evans, D.T.4
  • 20
    • 67650120099 scopus 로고    scopus 로고
    • HM1.24 is internalized from lipid rafts by clathrin-mediated endocytosis through interaction with adaptin
    • Masuyama N, Kuronita T, Tanaka R, et al. 2009. HM1.24 is internalized from lipid rafts by clathrin-mediated endocytosis through interaction with adaptin. J Biol Chem 284:15927-15941. http://dx.doi.org/10.1074 /jbc.M109.005124.
    • (2009) J Biol Chem , vol.284 , pp. 15927-15941
    • Masuyama, N.1    Kuronita, T.2    Tanaka, R.3
  • 21
    • 82955187052 scopus 로고    scopus 로고
    • Interferon-induced tetherin restricts vesicular stomatitis virus release in neurons
    • Sarojini S, Theofanis T, Reiss CS. 2011. Interferon-induced tetherin restricts vesicular stomatitis virus release in neurons. DNA Cell Biol 30: 965-974. http://dx.doi.org/10.1089/dna.2011.1384.
    • (2011) DNA Cell Biol , vol.30 , pp. 965-974
    • Sarojini, S.1    Theofanis, T.2    Reiss, C.S.3
  • 22
    • 84877596501 scopus 로고    scopus 로고
    • Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses
    • Cho H, Proll SC, Szretter KJ, Katze MG, Gale M, Diamond MS. 2013. Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses. Nat Med 19:458-464. http://dx.doi.org/10.1038/nm.3108.
    • (2013) Nat Med , vol.19 , pp. 458-464
    • Cho, H.1    Proll, S.C.2    Szretter, K.J.3    Katze, M.G.4    Gale, M.5    Diamond, M.S.6
  • 23
    • 84856947009 scopus 로고    scopus 로고
    • STAT1-independent control of a neurotropic measles virus challenge in primary neurons and infected mice
    • O'Donnell LA, Conway S, Rose RW, Nicolas E, Slifker M, Balachandran S, Rall GF. 2012. STAT1-independent control of a neurotropic measles virus challenge in primary neurons and infected mice. J Immunol 188: 1915-1923. http://dx.doi.org/10.4049/jimmunol.1101356.
    • (2012) J Immunol , vol.188 , pp. 1915-1923
    • O'Donnell, L.A.1    Conway, S.2    Rose, R.W.3    Nicolas, E.4    Slifker, M.5    Balachandran, S.6    Rall, G.F.7
  • 25
    • 0027426010 scopus 로고
    • The human CD46 molecule is a receptor for measles virus (Edmonston strain)
    • Dörig RE, Marcil A, Chopra A, Richardson CD. 1993. The human CD46 molecule is a receptor for measles virus (Edmonston strain). Cell 75:295- 305. http://dx.doi.org/10.1016/0092-8674(93)80071-L.
    • (1993) Cell , vol.75 , pp. 295-305
    • Dörig, R.E.1    Marcil, A.2    Chopra, A.3    Richardson, C.D.4
  • 28
    • 0033937220 scopus 로고    scopus 로고
    • Measles virus spread between neurons requires cell contact but not CD46 expression, syncytium formation, or extracellular virus production
    • Lawrence DMP, Patterson CE, Gales TL, D'Orazio JL, Vaughn MM, Rall GF. 2000. Measles virus spread between neurons requires cell contact but not CD46 expression, syncytium formation, or extracellular virus production. J Virol 74:1908-1918. http://dx.doi.org/10.1128/JVI.74.4.1908 -1918.2000.
    • (2000) J Virol , vol.74 , pp. 1908-1918
    • Lawrence, D.M.P.1    Patterson, C.E.2    Gales, T.L.3    D'Orazio, J.L.4    Vaughn, M.M.5    Rall, G.F.6
  • 29
    • 0032978961 scopus 로고    scopus 로고
    • Immune response-mediated protection of adult but not neonatal mice from neuron-restricted measles virus infection and central nervous system disease
    • Lawrence DMP, Vaughn MM, Belman AR, Cole JS, Rall GF. 1999. Immune response-mediated protection of adult but not neonatal mice from neuron-restricted measles virus infection and central nervous system disease. J Virol 73:1795-1801.
    • (1999) J Virol , vol.73 , pp. 1795-1801
    • Lawrence, D.M.P.1    Vaughn, M.M.2    Belman, A.R.3    Cole, J.S.4    Rall, G.F.5
  • 30
    • 0036226438 scopus 로고    scopus 로고
    • Immunemediated protection from measles virus-induced central nervous system disease is noncytolytic and gamma interferon dependent
    • Patterson CE, Lawrence DMP, Echols LA, Rall GF. 2002. Immunemediated protection from measles virus-induced central nervous system disease is noncytolytic and gamma interferon dependent. J Virol 76:4497- 4506. http://dx.doi.org/10.1128/JVI.76.9.4497-4506.2002.
    • (2002) J Virol , vol.76 , pp. 4497-4506
    • Patterson, C.E.1    Lawrence, D.M.P.2    Echols, L.A.3    Rall, G.F.4
  • 31
    • 36749096743 scopus 로고    scopus 로고
    • Altered levels of STAT1 and STAT3 influence the neuronal response to interferon gamma
    • Rose RW, Vorobyeva AG, Skipworth JD, Nicolas E, Rall GF. 2007. Altered levels of STAT1 and STAT3 influence the neuronal response to interferon gamma. J Neuroimmunol 192:145-156. http://dx.doi.org/10 .1016/j.jneuroim.2007.10.007.
    • (2007) J Neuroimmunol , vol.192 , pp. 145-156
    • Rose, R.W.1    Vorobyeva, A.G.2    Skipworth, J.D.3    Nicolas, E.4    Rall, G.F.5
  • 32
    • 0344683235 scopus 로고    scopus 로고
    • Guide for the care and use of laboratory animals
    • 8th ed. National Academies Press, Washington, DC.
    • National Research Council. 2011. Guide for the care and use of laboratory animals, 8th ed. National Academies Press, Washington, DC.
    • (2011)
  • 34
    • 84927513303 scopus 로고    scopus 로고
    • Homeostatic interferon expression in neurons is sufficient for early control of viral infection
    • Cavanaugh SE, Holmgren AM, Rall GF. 2015. Homeostatic interferon expression in neurons is sufficient for early control of viral infection. J Neuroimmunol 279:11-19. http://dx.doi.org/10.1016/j.jneuroim.2014.12 .012.
    • (2015) J Neuroimmunol , vol.279 , pp. 11-19
    • Cavanaugh, S.E.1    Holmgren, A.M.2    Rall, G.F.3
  • 35
    • 33645025137 scopus 로고    scopus 로고
    • CD4 T cell control primary measles virus infection of the CNS: regulation is dependent on combined activity with eitherCD8T cells or with B cells: CD4, CD8 or B cells alone are ineffective
    • Tishon A, Lewicki H, Andaya A, McGavern D, Martin L, Oldstone MBA. 2006. CD4 T cell control primary measles virus infection of the CNS: regulation is dependent on combined activity with eitherCD8T cells or with B cells: CD4, CD8 or B cells alone are ineffective. Virology 347: 234-245. http://dx.doi.org/10.1016/j.virol.2006.01.050.
    • (2006) Virology , vol.347 , pp. 234-245
    • Tishon, A.1    Lewicki, H.2    Andaya, A.3    McGavern, D.4    Martin, L.5    Oldstone, M.B.A.6
  • 36
    • 84865644751 scopus 로고    scopus 로고
    • Extended JAK activation and delayed STAT1 dephosphorylation contribute to the distinct signaling profile of CNS neurons exposed to interferon-gamma
    • Podolsky MA, Solomos AC, Durso LC, Evans SM, Rall GF, Rose RW. 2012. Extended JAK activation and delayed STAT1 dephosphorylation contribute to the distinct signaling profile of CNS neurons exposed to interferon-gamma. J Neuroimmunol 251:33-38. http://dx.doi.org/10 .1016/j.jneuroim.2012.06.006.
    • (2012) J Neuroimmunol , vol.251 , pp. 33-38
    • Podolsky, M.A.1    Solomos, A.C.2    Durso, L.C.3    Evans, S.M.4    Rall, G.F.5    Rose, R.W.6
  • 38
    • 84863268937 scopus 로고    scopus 로고
    • Cutting edge: paradoxical roles of BST2/tetherin in promoting type I IFN response and viral infection
    • Swiecki M, Wang Y, Gilfillan S, Lenschow DJ, Colonna M. 2012. Cutting edge: paradoxical roles of BST2/tetherin in promoting type I IFN response and viral infection. J Immunol 188:2488-2492. http://dx.doi.org /10.4049/jimmunol.1103145.
    • (2012) J Immunol , vol.188 , pp. 2488-2492
    • Swiecki, M.1    Wang, Y.2    Gilfillan, S.3    Lenschow, D.J.4    Colonna, M.5
  • 39
    • 64749093380 scopus 로고    scopus 로고
    • A CD317/tetherin-RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells
    • Rollason R, Korolchuk V, Hamilton C, Jepson M, Banting G. 2009. A CD317/tetherin-RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells. J Cell Biol 184:721-736. http://dx.doi.org/10.1083/jcb.200804154.
    • (2009) J Cell Biol , vol.184 , pp. 721-736
    • Rollason, R.1    Korolchuk, V.2    Hamilton, C.3    Jepson, M.4    Banting, G.5
  • 40
    • 64049111437 scopus 로고    scopus 로고
    • Noncytolytic clearance of Sindbis virus infection from neurons by gamma interferon is dependent on Jak/Stat signaling
    • Burdeinick-Kerr R, Govindarajan D, Griffin DE. 2009. Noncytolytic clearance of Sindbis virus infection from neurons by gamma interferon is dependent on Jak/Stat signaling. J Virol 83:3429-3435. http://dx.doi.org /10.1128/JVI.02381-08.
    • (2009) J Virol , vol.83 , pp. 3429-3435
    • Burdeinick-Kerr, R.1    Govindarajan, D.2    Griffin, D.E.3
  • 41
    • 77953959258 scopus 로고    scopus 로고
    • Recovery from viral encephalomyelitis: immunemediated noncytolytic virus clearance from neurons
    • Griffin DE. 2010. Recovery from viral encephalomyelitis: immunemediated noncytolytic virus clearance from neurons. Immunol Res 47: 123-133. http://dx.doi.org/10.1007/s12026-009-8143-4.
    • (2010) Immunol Res , vol.47 , pp. 123-133
    • Griffin, D.E.1
  • 42
    • 0036891082 scopus 로고    scopus 로고
    • Neuronal survival strategies in the face of RNA viral infection
    • Patterson CE, Daley JK, Rall GF. 2002. Neuronal survival strategies in the face of RNA viral infection. J Infect Dis 186:215-219.
    • (2002) J Infect Dis , vol.186 , pp. 215-219
    • Patterson, C.E.1    Daley, J.K.2    Rall, G.F.3
  • 43
    • 80052201398 scopus 로고    scopus 로고
    • Clearance of virus infection from the CNS
    • Griffin DE, Metcalf T. 2011. Clearance of virus infection from the CNS. Curr Opin Virol 1:216-221. http://dx.doi.org/10.1016/j.coviro.2011.05 .021.
    • (2011) Curr Opin Virol , vol.1 , pp. 216-221
    • Griffin, D.E.1    Metcalf, T.2
  • 44
    • 84869501348 scopus 로고    scopus 로고
    • CD8+ T cells patrol HSV-1-infected trigeminal ganglia and prevent viral reactivation
    • St Leger AJ, Hendricks RL. 2011. CD8+ T cells patrol HSV-1-infected trigeminal ganglia and prevent viral reactivation. J Neurovirol 17:528- 534. http://dx.doi.org/10.1007/s13365-011-0062-1.
    • (2011) J Neurovirol , vol.17 , pp. 528-534
    • St Leger, A.J.1    Hendricks, R.L.2
  • 45
    • 0034192426 scopus 로고    scopus 로고
    • CD8+ T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons
    • Liu T, Khanna KM, Chen X, Fink DJ, Hendricks RL. 2000. CD8+ T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons. J Exp Med 191:1459-1466. http://dx.doi.org/10.1084 /jem.191.9.1459.
    • (2000) J Exp Med , vol.191 , pp. 1459-1466
    • Liu, T.1    Khanna, K.M.2    Chen, X.3    Fink, D.J.4    Hendricks, R.L.5
  • 46
    • 84866539487 scopus 로고    scopus 로고
    • The molecular signature of tissue resident memory CD8 T cells isolated from the brain
    • Wakim LM, Woodward-Davis A, Liu R, et al. 2012. The molecular signature of tissue resident memory CD8 T cells isolated from the brain. J Immunol 189:3462-3471. http://dx.doi.org/10.4049/jimmunol.1201305.
    • (2012) J Immunol , vol.189 , pp. 3462-3471
    • Wakim, L.M.1    Woodward-Davis, A.2    Liu, R.3
  • 47
    • 78149278086 scopus 로고    scopus 로고
    • Memory T cells persisting within the brain after local infection show functional adaptations to their tissue of residence
    • Wakim LM, Woodward-Davis A, Bevan MJ. 2010. Memory T cells persisting within the brain after local infection show functional adaptations to their tissue of residence. Proc Natl Acad Sci U S A 107:17872- 17879. http://dx.doi.org/10.1073/pnas.1010201107.
    • (2010) Proc Natl Acad Sci U S A. , vol.107 , pp. 17872-17879
    • Wakim, L.M.1    Woodward-Davis, A.2    Bevan, M.J.3


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