Extended JAK activation and delayed STAT1 dephosphorylation contribute to the distinct signaling profile of CNS neurons exposed to interferon-gamma

Journal of Neuroimmunology

Volumn 251, Issue 1-2, 2012, Pages 33-38

  Podolsky, Michael A ^a   Solomos, Andreas C ^a   Durso, Lisa C ^a   Evans, Stephanie M ^a   Rall, Glenn F ^b   Rose, R Wesley ^a  

^a ARCADIA UNIVERSITY   (United States)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

CNS neurons; Interferon gamma; JAK; Signal transduction; STAT

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; JANUS KINASE; JANUS KINASE 1; JANUS KINASE 2; STAT1 PROTEIN;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; CYTOKINE RESPONSE; EMBRYO; ENZYME ACTIVATION; ENZYME INACTIVATION; FEEDBACK SYSTEM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ANIMALS; CELLS, CULTURED; FIBROBLASTS; HIPPOCAMPUS; INTERFERON-GAMMA; JANUS KINASE 1; JANUS KINASE 2; MICE; NEURONS; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR;

EID: 84865644751     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2012.06.006     Document Type: Article

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