Short Proline-Rich Antimicrobial Peptides Inhibit Either the Bacterial 70S Ribosome or the Assembly of its Large 50S Subunit

ChemBioChem

Volumn 16, Issue 16, 2015, Pages 2304-2308

  Krizsan, Andor ^a   Prahl, Caroline ^a   Goldbach, Tina ^a   Knappe, Daniel ^a   Hoffmann, Ralf ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

antibiotics; apidaecin; Gram negative bacteria; oncocin; peptides; protein translation

Indexed keywords

API 137; API 88; APIDAECIN; CHLORAMPHENICOL; CLINDAMYCIN; DROSOCIN; ERYTHROMYCIN; KANAMYCIN; ONC 112; ONC 72; ONCOCIN; POLYPEPTIDE ANTIBIOTIC AGENT; PROLINE RICH PROTEIN; STREPTOMYCIN; TETRACYCLINE; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; PROLINE; PROTEIN BINDING;

50S RIBOSOMAL SUBUNIT; 70S RIBOSOMAL SUBUNIT; AMINO ACID SEQUENCE; ARTICLE; BACTERIAL GROWTH; BINDING SITE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BINDING; DRUG MECHANISM; ESCHERICHIA COLI; IC50; INHIBITION CONSTANT; LARGE RIBOSOMAL SUBUNIT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; RIBOSOME; CHEMISTRY; KINETICS; METABOLISM; MICROBIAL SENSITIVITY TEST; MOLECULAR GENETICS;

AMINO ACID SEQUENCE; ANTIMICROBIAL CATIONIC PEPTIDES; ESCHERICHIA COLI; KINETICS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PROLINE; PROTEIN BINDING; RIBOSOME SUBUNITS, LARGE, BACTERIAL;

EID: 84945199329     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201500375     Document Type: Article

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