Identification and characterization of ANO9 in stage II and III colorectal carcinoma

Oncotarget

Volumn 6, Issue 30, 2015, Pages 29324-29334

  Li, Chunxiang ^a   Cai, Sanjun ^b   Wang, Xishan ^a,c   Jiang, Zheng ^a,c  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

^c Colorectal Cancer Institute of the Heilongjiang Academy of Medical Sciences ^*  (China)

Author keywords

ANO9; Colorectal cancer; Metastasis; Prognosis

Indexed keywords

ANOCTAMIN 9 PROTEIN; CARRIER PROTEINS AND BINDING PROTEINS; CHOLECYSTOKININ OCTAPEPTIDE; MESSENGER RNA; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; TMEM16J PROTEIN, HUMAN; TUMOR MARKER;

AGED; ANOCTAMIN 9 GENE; ARTICLE; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CARCINOGENESIS; CELL INVASION; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; METASTASIS; REAL TIME POLYMERASE CHAIN REACTION; TUMOR INVASION; VERY ELDERLY; APOPTOSIS; CACO-2 CELL LINE; CARCINOMA; CELL MOTION; CELL PROLIFERATION; COLORECTAL NEOPLASMS; GENE EXPRESSION REGULATION; GENETICS; HCT 116 CELL LINE; KAPLAN MEIER METHOD; METABOLISM; MIDDLE AGED; MORTALITY; PATHOLOGY; PROPORTIONAL HAZARDS MODEL; RISK FACTOR; RNA INTERFERENCE; SECONDARY; SIGNAL TRANSDUCTION; TIME FACTOR; TREATMENT OUTCOME; TUMOR RECURRENCE; UPREGULATION;

AGED; AGED, 80 AND OVER; APOPTOSIS; BIOMARKERS, TUMOR; CACO-2 CELLS; CARCINOMA; CELL MOVEMENT; CELL PROLIFERATION; COLORECTAL NEOPLASMS; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; MALE; MEMBRANE PROTEINS; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM RECURRENCE, LOCAL; PROPORTIONAL HAZARDS MODELS; REAL-TIME POLYMERASE CHAIN REACTION; RISK FACTORS; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; TREATMENT OUTCOME; UP-REGULATION;

EID: 84945162094     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4979     Document Type: Article

References (24)

1. Shike M, Winawer SJ, Greenwald PH, Bloch A, Hill MJ and Swaroop SV. Primary prevention of colorectal cancer. The WHO Collaborating Centre for the Prevention of Colorectal Cancer. Bull World Health Organ. 1990; 68:377-385.
2. Haggar FA and Boushey RP. Colorectal cancer epidemiology: incidence, mortality, survival, and risk factors. Clin Colon Rectal Surg. 2009; 22:191-197.
3. Cserni G. Nodal staging of colorectal carcinomas and sentinel nodes. J Clin Pathol. 2003; 56:327-335.
4. Gramont A. Adjuvant therapy of stage II and III colon cancer. Semin Oncol. 2005; 32:11-14.
5. Chatla C, Jhala NC, Katkoori VR, Alexander D, Meleth S, Grizzle WE and Manne U. Recurrence and survival predictive value of phenotypic expression of Bcl-2 varies with tumor stage of colorectal adenocarcinoma. Cancer Biomark. 2005; 1:241-250.
6. Picollo A, Malvezzi M and Accardi A. TMEM16 proteins: unknown structure and confusing functions. J Mol Biol. 2015; 427:94-105.
7. Li C, Cai S, Wang X and Jiang Z. Hypomethylationassociated up-regulation of TCF3 expression and recurrence in stage II and III colorectal cancer. Plos One. 2014; 9:e112005.
8. Jiang Z, Xu Y and Cai S. Down-regulated GAS1 expression correlates with recurrence in stage II and III colorectal cancer. Hum Pathol. 2011; 42:361-368.
9. Kallioniemi OP, Wagner U, Kononen J and Sauter G. Tissue microarray technology for high-throughput molecular profiling of cancer. Hum Mol Genet. 2001; 10:657-662.
10. Xu L and Deng X. Protein kinase Ciota promotes nicotineinduced migration and invasion of cancer cells via phosphorylation of micro-and m-calpains. J Biol Chem. 2006; 281:4457-4466.
11. Suzuki J, Fujii T, Imao T, Ishihara K, Kuba H and Nagata S. Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members. J Biol Chem. 2013; 288:13305-13316.
12. Tian Y, Schreiber R and Kunzelmann K. Anoctamins are a family of Ca2+-activated Cl-channels. J Cell Sci. 2012; 125:4991-4998.
13. Schreiber R, Uliyakina I, Kongsuphol P, Warth R, Mirza M, Martins JR and Kunzelmann K. Expression and function of epithelial anoctamins. J Biol Chem. 2010; 285:7838-7845.
14. Manoury B, Tamuleviciute A and Tammaro P. TMEM16A/anoctamin 1 protein mediates calcium-activated chloride currents in pulmonary arterial smooth muscle cells. J Physiol. 2010; 588:2305-2314.
15. Duvvuri U, Shiwarski DJ, Xiao D, Bertrand C, Huang X, Edinger RS, Rock JR, Harfe BD, Henson BJ, Kunzelmann K, Schreiber R, Seethala RS, Egloff AM, Chen X, Lui VW and Grandis JR, et al. TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression. Cancer Res. 2012; 72:3270-3281.
16. Huang WC, Xiao S, Huang F, Harfe BD, Jan YN and Jan LY. Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons. Neuron. 2012; 74:179-192.
17. Huang F, Zhang H, Wu M, Yang H, Kudo M, Peters CJ, Woodruff PG, Solberg OD, Donne ML, Huang X, Sheppard D, Fahy JV, Wolters PJ, Hogan BL, Finkbeiner WE and Li M, et al. Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proc Natl Acad Sci U S A. 2012; 109:16354-16359.
18. Cho H, Yang YD, Lee J, Lee B, Kim T, Jang Y, Back SK, Na HS, Harfe BD, Wang F, Raouf R, Wood JN and Oh U. The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons. Nat Neurosci. 2012; 15:1015-1021.
19. Mazzone A, Eisenman ST, Strege PR, Yao Z, Ordog T, Gibbons SJ and Farrugia G. Inhibition of cell proliferation by a selective inhibitor of the Ca(2+)-activated Cl(-) channel, Ano1. Biochem Biophys Res Commun. 2012; 427:248-253.
20. Wong XM, Younger S, Peters CJ, Jan YN and Jan LY. Subdued, a TMEM16 family Ca(2)(+)-activated Cl(-) channel in Drosophila melanogaster with an unexpected role in host defense. Elife. 2013; 2:e862.
21. Lee B, Cho H, Jung J, Yang YD, Yang DJ and Oh U. Anoctamin 1 contributes to inflammatory and nerve-injury induced hypersensitivity. Mol Pain. 2014; 10:5.
22. Wanitchakool P, Wolf L, Koehl GE, Sirianant L, Schreiber R, Kulkarni S, Duvvuri U and Kunzelmann K. Role of anoctamins in cancer and apoptosis. Philos Trans R Soc Lond B Biol Sci. 2014; 369:20130096.
23. Trarbach T, Kubicka S, Hacker U, Ridwelski K and Reinacher-Schick A. [Adjuvant therapy of colon carcinoma]. Onkologie. 2008; 31 Suppl 5:19-23.
24. De Dosso S, Sessa C and Saletti P. Adjuvant therapy for colon cancer: present and perspectives. Cancer Treat Rev. 2009; 35:160-166.