Telomere Attrition and Elongation after Chronic Dialysis Initiation in Patients with End-Stage Renal Disease

Blood Purification

Volumn 41, Issue 1-3, 2016, Pages 25-33

  Kato, Sawako ^a   Shiels, Paul G ^c   McGuinness, Dagmara ^c   Lindholm, Bengt ^d   Stenvinkel, Peter ^d   Nordfors, Louise ^d   Qureshi, Abdul Rashid ^d   Yuzawa, Yukio ^b   Matsuo, Seiichi ^a   Maruyama, Shoichi ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Ageing; Dialysis; Inflammation; Leukocyte; Telomere length

Indexed keywords

DNA; BIOLOGICAL MARKER;

ADULT; AGED; AGING; ARTICLE; BLOOD SAMPLING; DIALYSIS; END STAGE RENAL DISEASE; FEMALE; HEMODIALYSIS PATIENT; HUMAN; INFLAMMATION; JAPANESE (CITIZEN); KIDNEY FUNCTION; LEUKOCYTE; LEUKOCYTE COUNT; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TELOMERE; TELOMERE ELONGATION; BLOOD; CELL AGING; CHEMISTRY; GENETICS; HEMODIALYSIS; KIDNEY FAILURE, CHRONIC; METABOLISM; MIDDLE AGED; MONONUCLEAR CELL; PATHOLOGY; PROSPECTIVE STUDY; REAL TIME POLYMERASE CHAIN REACTION; STATISTICAL MODEL; TELOMERE HOMEOSTASIS; TELOMERE SHORTENING;

AGED; BIOMARKERS; CELL AGING; FEMALE; HUMANS; KIDNEY FAILURE, CHRONIC; LEUKOCYTE COUNT; LEUKOCYTES, MONONUCLEAR; LOGISTIC MODELS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; REAL-TIME POLYMERASE CHAIN REACTION; RENAL DIALYSIS; TELOMERE; TELOMERE HOMEOSTASIS; TELOMERE SHORTENING;

EID: 84945152238     PISSN: 02535068     EISSN: 14219735     Source Type: Journal    
DOI: 10.1159/000440971     Document Type: Article

References (39)

1. Blackburn EH: Telomeres and telomerase: The means to the end (Nobel lecture). Angew Chem Int Ed Engl 2010; 49: 7405-7421.
2. Blasco MA: Telomeres and human disease: ageing, cancer and beyond. Nat Rev Genet 2005; 6: 611-622.
3. Kaszubowska L: Telomere shortening and ageing of the immune system. J Physiol Pharmacol 2008; 59(suppl 9):169-186.
4. Jiang X, Dong M, Cheng J, Huang S, He Y, Ma K, Tang B, Guo Y: Decreased leukocyte telomere length (LTL) is associated with stroke but unlikely to be causative. PLoS One 2013; 8:e68254.
5. von Zglinicki T, Serra V, Lorenz M, Saretzki G, Lenzen-Grossimlighaus R, Gessner R, Risch A, Steinhagen-Thiessen E: Short telomeres in patients with vascular dementia: an indicator of low antioxidative capacity and a possible risk factor? Lab Invest 2000; 80: 1739-1747.
6. Brouilette SW, Moore JS, McMahon AD, Thompson JR, Ford I, Shepherd J, Packard CJ, Samani NJ; West of Scotland Coronary Prevention Study Group: Telomere length, risk of coronary heart disease, and statin treatment in the west of Scotland primary prevention study: A nested case-control study. Lancet 2007; 369: 107-114.
7. Tamura Y, Izumiyama-Shimomura N, Kimbara Y, Nakamura K, Ishikawa N, Aida J, Chiba Y, Mori S, Arai T, Aizawa T, Araki A, Takubo K, Ito H: β-cell telomere attrition in diabetes: inverse correlation between HbA1c and telomere length. J Clin Endocrinol Metab 2014; 99: 2771-2777.
8. Ornish D, Lin J, Chan JM, Epel E, Kemp C, Weidner G, Marlin R, Frenda SJ, Magbanua MJ, Daubenmier J, Estay I, Hills NK, Chainani-Wu N, Carroll PR, Blackburn EH: Effect of comprehensive lifestyle changes on telomerase activity and telomere length in men with biopsy-proven low-risk prostate cancer: 5-year follow-up of a descriptive pilot study. Lancet Oncol 2013; 14: 1112-1120.
9. Stenvinkel P, Larsson TE: Chronic kidney disease: A clinical model of premature aging. Am J Kidney Dis 2013; 62: 339-351.
10. Kooman JP, Schols AM, Shiels PG, Stenvinkel P: Chronic kidney disease and premature aging-when more leads to less. Nature Rev Nephrol 2014; 10: 732-742.
11. Stenvinkel P, Carrero JJ, Axelsson J, Lindholm B, Heimbürger O, Massy Z: Emerging biomarkers for evaluating cardiovascular risk in the chronic kidney disease patient: how do new pieces fit into the uremic puzzle? Clin J Am Soc Nephrol 2008; 3: 505-521.
12. Takemoto Y, Naganuma T, Yoshimura R: Biocompatibility of the dialysis membrane. Contrib Nephrol 2011; 168: 139-145.
13. Carrero JJ, Stenvinkel P, Fellström B, Qureshi AR, Lamb K, Heimbürger O, Bárány P, Radhakrishnan K, Lindholm B, Soveri I, Nordfors L, Shiels PG: Telomere attrition is associated with inflammation, low fetuin-A levels and high mortality in prevalent haemodialysis patients. J Intern Med 2008; 263: 302-312.
14. Hirashio S, Nakashima A, Doi S, Anno K, Aoki E, Shimamoto A, Yorioka N, Kohno N, Masaki T, Tahara H: Telomeric g-tail length and hospitalization for cardiovascular events in hemodialysis patients. Clin J Am Soc Nephrol 2014; 9: 2117-2122.
15. Stevenson KS, Radhakrishnan K, Patterson CS, McMillan LC, Skeldon KD, Buist L, Padgett MJ, Shiels PG: Breath ethane peaks during a single haemodialysis session and is associated with time on dialysis. J Breath Res 2008; 2: 026004.
16. Patterson CS, McMillan LC, Stevenson K, Radhakrishnan K, Shiels PG, Padgett MJ, Skeldon KD: Dynamic study of oxidative stress in renal dialysis patients based on breath ethane measured by optical spectroscopy. J Breath Res 2007; 1: 026005.
17. Detsky AS, McLaughlin JR, Baker JP, Johnston N, Whittaker S, Mendelson RA, Jeejeebhoy KN: What is subjective global assessment of nutritional status? JPEN J Parenter Enteral Nutr 1987; 11: 8-13.
18. Matsuo S, Imai E, Horio M, Yasuda Y, Tomita K, Nitta K, Yamagata K, Tomino Y, Yokoyama H, Hishida A: Revised equations for estimated GFR from serum creatinine in Japan. Am J Kidney Dis 2009; 53: 982-992.
19. Gingell-Littlejohn M, McGuinness D, McGlynn LM, Kingsmore D, Stevenson KS, Koppelstaetter C, Clancy MJ, Shiels PG: Pretransplant CDKN2A expression in kidney biopsies predicts renal function and is a future component of donor scoring criteria. PLoS One 2013; 8:e68133.
20. Graakjaer J, Bischoff C, Korsholm L, Holstebroe S, Vach W, Bohr VA, Christensen K, Kølvraa S: The pattern of chromosome-specific variations in telomere length in humans is determined by inherited, telomere-near factors and is maintained throughout life. Mech Ageing Dev 2003; 124: 629-640.
21. Graakjaer J, Der-Sarkissian H, Schmitz A, Bayer J, Thomas G, Kolvraa S, Londono-Vallejo JA: Allele-specific relative telomere lengths are inherited. Hum Genet 2006; 119: 344-350.
22. Huda N, Tanaka H, Herbert BS, Reed T, Gilley D: Shared environmental factors associated with telomere length maintenance in elderly male twins. Aging Cell 2007; 6: 709-713.
23. Robertson T, Batty GD, Der G, Green MJ, Mc-Glynn LM, McIntyre A, Shiels PG, Benzeval M: Is telomere length socially patterned? Evidence from the west of scotland twenty-07 study. PLoS One 2012; 7:e41805.
24. Boccardi V, Esposito A, Rizzo MR, Marfella R, Barbieri M, Paolisso G: Mediterranean diet, telomere maintenance and health status among elderly. PLoS One 2013; 8:e62781.
25. Houben JM, Moonen HJ, van Schooten FJ, Hageman GJ: Telomere length assessment: biomarker of chronic oxidative stress? Free Radic Biol Med 2008; 44: 235-246.
26. Benetti R, Garcia-Cao M, Blasco MA: Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres. Nature genetics 2007; 39: 243-250.
27. Flynn RL, Centore RC, O'Sullivan RJ, Rai R, Tse A, Songyang Z, Chang S, Karlseder J, Zou L: TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA. Nature 2011; 471: 532-536.
28. Aviv A, Chen W, Gardner JP, Kimura M, Brimacombe M, Cao X, Srinivasan SR, Berenson GS: Leukocyte telomere dynamics: longitudinal findings among young adults in the Bogalusa heart study. Am J Epidemiol 2009; 169: 323-329.
29. Farzaneh-Far R, Lin J, Epel E, Lapham K, Blackburn E, Whooley MA: Telomere length trajectory and its determinants in persons with coronary artery disease: longitudinal findings from the heart and soul study. PLoS One 2010; 5:e8612.
30. Nordfjäll K, Svenson U, Norrback KF, Adolfsson R, Lenner P, Roos G: The individual blood cell telomere attrition rate is telomere length dependent. PLoS Genet 2009; 5:e1000375.
31. Verhulst S, Aviv A, Benetos A, Berenson GS, Kark JD: Do leukocyte telomere length dynamics depend on baseline telomere length? An analysis that corrects for 'regression to the mean'. Eur J Epidemiol 2013; 28: 859-866.
32. Massy ZA, Stenvinkel P, Drueke TB: The role of oxidative stress in chronic kidney disease. Semin Dial 2009; 22: 405-408.
33. Himmelfarb J, Stenvinkel P, Ikizler TA, Hakim RM: The elephant in uremia: oxidant stress as a unifying concept of cardiovascular disease in uremia. Kidney Int 2002; 62: 1524-1538.
34. Farzaneh-Far R, Lin J, Epel ES, Harris WS, Blackburn EH, Whooley MA: Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease. JAMA 2010; 303: 250-257.
35. Boccardi V, Barbieri M, Rizzo MR, Marfella R, Esposito A, Marano L, Paolisso G: A new pleiotropic effect of statins in elderly: modulation of telomerase activity. FASEB J 2013; 27: 3879-3885.
36. Simpson RJ, Cosgrove C, Chee MM, McFarlin BK, Bartlett DB, Spielmann G, O'Connor DP, Pircher H, Shiels PG: Senescent phenotypes and telomere lengths of peripheral blood tcells mobilized by acute exercise in humans. Exerc Immunol Rev 2010; 16: 40-55.
37. Shiels PG: CDKN2A might be better than telomere length in determining individual health status. BMJ 2012; 344:e1415.
38. Shiels PG: Improving precision in investigating aging: why telomeres can cause problems. J Gerontol A Biol Sci Med Sci 2010; 65: 789-791.
39. Hovatta I, de Mello VD, Kananen L, Lindström J, Eriksson JG, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Peltonen M, Tuomilehto J, Uusitupa M: Leukocyte telomere length in the Finnish diabetes prevention study. PLoS One 2012; 7:e34948.