Ubiquitination and regulation of Smad7 in the TGF-β1/Smad signaling of aristolochic acid nephropathy

Toxicology Mechanisms and Methods

Volumn 25, Issue 8, 2015, Pages 645-652

  Tian, Yahui ^a   Liao, Fangfang ^a   Wu, Guoying ^b   Chang, Di ^a   Yang, Yaohui ^a   Dong, Xiaokai ^a   Zhang, Zhongwen ^a   Zhang, Yu ^c   Wu, Guojuan ^a  

^a BEIJING UNIVERSITY OF AGRICULTURE   (China)

^b Maternity and Child Care Center   (China)

^c Syngenta Biotechnology (China) Co Ltd   (China)

Author keywords

Aristolochic acid nephropathy; Arkadia; Smad7; TGF 1 Smad signaling pathway; UCH37

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ARISTOLOCHIC ACID; ARKADIA; MESSENGER RNA; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1; UBIQUITIN C TERMINAL HYDROLASE 5; UBIQUITIN THIOLESTERASE; UNCLASSIFIED DRUG; VIMENTIN; ARISTOLOCHIC ACID I; CARCINOGEN; PROTEIN SERINE THREONINE KINASE; RNF111 PROTEIN, MOUSE; SMAD7 PROTEIN, MOUSE; TGF-BETA TYPE I RECEPTOR; TGFB1 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; UBIQUITIN PROTEIN LIGASE; UCH37 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARISTOLOCHIC ACID NEPHROPATHY; ARTICLE; CELL CULTURE; CONTROLLED STUDY; EXPRESSION VECTOR; KIDNEY DISEASE; KIDNEY FIBROSIS; KIDNEY PARENCHYMA; KIDNEY TUBULE EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UBIQUITINATION; WESTERN BLOTTING; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; KIDNEY TUBULE; METABOLISM; NEPHRITIS; PHOSPHORYLATION; PROTEIN PROCESSING; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ANIMALS; ARISTOLOCHIC ACIDS; CARCINOGENS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; KIDNEY TUBULES; MICE; NEPHRITIS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UBIQUITIN THIOLESTERASE; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84945136802     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.3109/15376516.2015.1061082     Document Type: Article

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