Decreased frequencies of circulating CD4+ T follicular helper cells associated with diminished plasma IL-21 in active pulmonary tuberculosis

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Kumar, Nathella Pavan ^a,b   Sridhar, Rathinam ^c   Hanna, Luke E ^b   Banurekha, Vaithilingam V ^b   Nutman, Thomas B ^d   Babu, Subash ^a,d  

^a National Institutes of Health International Center for Excellence in Research   (India)

^b NATIONAL INSTITUTE FOR RESEARCH IN TUBERCULOSIS   (India)

^c Government Stanley Hospital   (India)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR5; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; INDUCIBLE T CELL COSTIMULATOR; INTERLEUKIN 10; INTERLEUKIN 21; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; BACTERIAL ANTIGEN; CD3 ANTIGEN; ICOS PROTEIN, HUMAN; IL10 PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE; PDCD1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA;

ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EX VIVO STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; LATENT TUBERCULOSIS; LUNG TUBERCULOSIS; MEMORY CELL; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; T FOLLICULAR HELPER CELL; BLOOD; HELPER CELL; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; LYMPHOCYTE COUNT; METABOLISM; PLASMA CELL;

ANTIGENS, BACTERIAL; ANTIGENS, CD3; CTLA-4 ANTIGEN; HUMANS; IMMUNOLOGIC MEMORY; INDUCIBLE T-CELL CO-STIMULATOR PROTEIN; INTERLEUKIN-10; INTERLEUKINS; LATENT TUBERCULOSIS; LYMPHOCYTE COUNT; PLASMA CELLS; PROGRAMMED CELL DEATH 1 RECEPTOR; T-LYMPHOCYTES, HELPER-INDUCER; TRANSFORMING GROWTH FACTOR BETA; TUBERCULOSIS, PULMONARY;

EID: 84908550506     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0111098     Document Type: Article

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