Synthesis of Fused Polycyclic Indoles by Brønsted Acid-Catalyzed Intramolecular Alkylation of Indoles with Alcohols

Journal of Organic Chemistry

Volumn 80, Issue 20, 2015, Pages 10421-10430

  Suárez, Anisley ^a   Gohain, Mukut ^a   Fernández Rodríguez, Manuel A ^a   Sanz, Roberto ^a  

^a UNIVERSITY OF BURGOS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; FRIEDEL-CRAFTS REACTION;

INTRAMOLECULAR ALKYLATION; INTRAMOLECULAR FRIEDEL-CRAFTS;

SYNTHESIS (CHEMICAL);

(4 METHOXYPHENYL) [2 [(1 METHYL 1H INDOL 2 YL)METHYL]PHENYL]METHANOL; (4 METHOXYPHENYL) [2 [(3 METHYL 1H INDOL 1 YL)METHYL]PHENYL]METHANOL; 1 (4 METHOXYPHENYL) 1 [2 [(3 METHYL 1H INDOL 1 YL)METHYL]PHENYL]ETHANOL; 1 CYCLOPROPYL 1 [2 [(1 METHYL 1H INDOL 2 YL)METHYL]PHENYL]ETHANOL; 1 [2 (1 METHYL 1H INDOL 2 YL)PHENYL] 3 PHENYLPROP 2 EN 1 OL; 1 [2 (1 METHYL 1H INDOL 2 YL)PHENYL]BUTAN 1 OL; 1 [2 [(1 METHYL 1H INDOL 2 YL)METHYL]PHENYL] 1 (THIOPEN 2 YL)ETHANOL; 1 [2 [(1 METHYL 1H INDOL 2 YL)METHYL]PHENYL] 3 PHENYLPROP 2 EN 1 OL; 10 CYCLOPROPYL 5 METHYL 10 PHENYL 5,10 DIHYDROINDENO[1,2 B]INDOLE; 10 ETHYL 5 METHYL 10 (THIOPHEN 2 YL) 5,10 DIHYDROINDENO[1,2 B]INDOLE; 2 METHYL [2 [(3 METHYL 1H INDOL 1 YL)METHYL]PHENYL]PROPAN 1 OL; 2 [2 (1 METHYL 1H INDOL 2 YL)PHENYL] 4 (THIOPEN 3 YL)BUT 3 YN 2 OL; 2 [2 (1 METHYL 1H INDOL 2 YL)PHENYL] 4 PHENYLBUT 3 EN 2 OL; 2 [2 [(1H INDOL 1 YL)METHYL]PHENYL]PROPAN 2 OL; 5,10 DIMETHYL 10 PHENYL 5,10 DIHYDROINDENO[1,2 B]INDOLE; ALCOHOL DERIVATIVE; BRONSTED ACID; CYCLOPROPYL [2 [(1 METHYL 1H INDOL 2 YL)METHYL]PHENYL](PHENYL)METHANOL; DICYCLOPROPYL (1,1' DIMETHYL 1H,1'H [2,3' BIINDOL] 2' YL)METHANOL; INDOLE DERIVATIVE; ISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; [2 (1 METHYL 1H INDOL 2 YL)THIOPHEN 3 YL]BIS PARA TOLYLMETHANOL; [2 (1H INDOL 2 YL)PHENYL] (4 METHOXYPHENYL)METHANOL; [2 (1H INDOL 2 YL)PHENYL] (THIOPEN 2 YL)METHANOL; [2 [(1 METHYL 1H INDOL 2 YL)METHYL]PHENYL] (4 METHOXYPHENYL)METHANOL; [2 [(1H INDOL 1 YL)METHYL]PHENYL](4 METHOXYPHENYL)METHANOL; [2 [(1H INDOL 1 YL)METHYL]PHENYL](CYCLOPROPYL)(PHENYL)METHANOL; [2 [(1H INDOL 2 YL)METHYL]PHENYL]BIS PARA TOLYLMETHANOL; [2 [(3 METHYL 1H INDOL 1 YL)METHYL]PHENYL]BIS PARA TOLYLMETHANOL;

ALKYLATION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; COLUMN CHROMATOGRAPHY; DRUG SYNTHESIS; FRIEDEL CRAFTS REACTION; METHYLATION; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 84944910091     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/acs.joc.5b02048     Document Type: Article

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