A click chemistry approach for the synthesis of mono and bis aryloxy linked coumarinyl triazoles as anti-tubercular agents

European Journal of Medicinal Chemistry

Volumn 105, Issue , 2015, Pages 194-207

  Anand, Ashish ^a   Naik, Reshma J ^a   Revankar, Hrishikesh M ^a   Kulkarni, Manohar V ^a   Dixit, Sheshagiri R ^b   Joshi, Shrinivas D ^b  

^a KARNATAK UNIVERSITY   (India)

^b S E T S COLLEGE OF PHARMACY   (India)

Author keywords

1,2,3 triazoles; 2H chromen 2 one; 3D QSAR; Anti tubercular; Click reaction; Molecular docking; Surflex dock

Indexed keywords

6 METHYL 4 ((4 ((4 ((1 ((6 METHYL 2 OXO 2H CHROMEN 4 YL)METHYL) 1H 1,2,3 TRIAZOL 4 YL)METHOXY)PHENOXY)METHYL) 1H 1,2,3 TRIAZOL 1 YL)METHYL) 2H CHROMEN 2 ONE; ALKYNE; AZIDE; CHROMENE DERIVATIVE; CIPROFLOXACIN; COUMARIN DERIVATIVE; ETHER DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PYRAZINAMIDE; STREPTOMYCIN; TRIAZOLE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CLICK CHEMISTRY; COMPARATIVE MOLECULAR FIELD ANALYSIS; CONTROLLED STUDY; CYCLOADDITION; DRUG SCREENING; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR MODEL; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REACTION ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; MICROBIAL SENSITIVITY TEST; SYNTHESIS;

ANTITUBERCULAR AGENTS; CLICK CHEMISTRY; COUMARINS; DOSE-RESPONSE RELATIONSHIP, DRUG; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 84944895445     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2015.10.019     Document Type: Article

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