FACT Disrupts Nucleosome Structure by Binding H2A-H2B with Conserved Peptide Motifs

Molecular Cell

Volumn 60, Issue 2, 2015, Pages 294-306

  Kemble, David J ^a   McCullough, Laura L ^a   Whitby, Frank G ^a   Formosa, Tim ^a   Hill, Christopher P ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Crystal structure; Histone binding; Histone chaperone; Nucleosome reorganization; Spt16 Pob3

Indexed keywords

CHAPERONE; HETERODIMER; HISTONE H2A; HISTONE H2B; PROTEIN FACT; PROTEIN POB3; PROTEIN SPT16; SACCHAROMYCES CEREVISIAE PROTEIN; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; FACT PROTEIN, S CEREVISIAE; HIGH MOBILITY GROUP PROTEIN; HISTONE; NUCLEOSOME; POB3 PROTEIN, S CEREVISIAE; PROTEIN BINDING; SPT16 PROTEIN, S CEREVISIAE; TRANSCRIPTION ELONGATION FACTOR; TRANSCRIPTION FACTOR;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; NONHUMAN; NUCLEOSOME; PEPTIDE MAPPING; PHENOTYPE; POINT MUTATION; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STOICHIOMETRY; CHEMISTRY; CONSERVED SEQUENCE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; MOLECULAR MODEL; PROTEIN MULTIMERIZATION; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; X RAY CRYSTALLOGRAPHY;

AMINO ACID MOTIFS; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; HIGH MOBILITY GROUP PROTEINS; HISTONES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEOSOMES; PROTEIN BINDING; PROTEIN MULTIMERIZATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ELONGATION FACTORS;

EID: 84944873198     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.09.008     Document Type: Article

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