The 9p21.3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN2A

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Vijayakrishnan, Jayaram ^a   Henrion, Marc ^a   Moorman, Anthony V ^c   Fiege, Bettina ^d   Kumar, Rajiv ^b   Inacio Da Silva Filho, Miguel ^b   Holroyd, Amy ^b   Koehler, Rolf ^c   Thomsen, Hauke ^b   Irving, Julie A ^d   Allan, James M ^d   Lightfoot, Tracy ^e   Roman, Eve ^e   Kinsey, Sally E ^f,g   Sheridan, Eamonn ^g   Thompson, Pamela D ^h   Hoffmann, Per ^i,o   Nöthen, Markus M ^i,p   Mühleisen, Thomas W ^i,j   Eisele, Lewin ^k   Bartram, Claus R ^c,l   Schrappe, Martin ^m   Greaves, Mel ^a   Hemminki, Kari ^b,n   Harrison, Christine J ^d   Stanulla, Martin ^m   Houlston, Richard S ^a   more..

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

^e UNIVERSITY OF YORK   (United Kingdom)

^f LEEDS GENERAL INFIRMARY   (United Kingdom)

^g UNIVERSITY OF LEEDS   (United Kingdom)

^h CRC Paediatric/Familial Cancer R   (United Kingdom)

ⁱ UNIVERSITY OF BONN   (Germany)

^j GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^k UNIVERSITY HOSPITAL ESSEN   (Germany)

^l HANNOVER MEDICAL SCHOOL   (Germany)

^m UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

ⁿ LUND UNIVERSITY   (Sweden)

^o UNIVERSITY HOSPITAL BASEL   (Switzerland)

^p FORSCHUNGSZENTRUM JÜLICH   (Germany)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A;

CHILD; CHROMOSOME 9; EXON; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HUMAN; MALE; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PRESCHOOL CHILD; PREVALENCE; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED KINGDOM;

CHILD; CHILD, PRESCHOOL; CHROMOSOMES, HUMAN, PAIR 9; CYCLIN-DEPENDENT KINASE INHIBITOR P16; EXONS; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PREVALENCE; RISK FACTORS; UNITED KINGDOM;

EID: 84944706694     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep15065     Document Type: Article

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