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Volumn 98, Issue 7, 2013, Pages 1081-1088

Genes commonly deleted in childhood B-cell precursor acute lymphoblastic leukemia: Association with cytogenetics and clinical features

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; TRANSCRIPTION FACTOR ETV6; TRANSCRIPTION FACTOR PAX5; TRANSCRIPTION FACTOR RUNX1;

EID: 84879593764     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2013.085175     Document Type: Article
Times cited : (130)

References (42)
  • 1
    • 77952316067 scopus 로고    scopus 로고
    • Acute Lymphoblastic Leukaemia
    • Heim S, Mitelman F, (eds.), 3rd ed. New Jersey, USA: John Wiley and Son Inc
    • Harrison CJ, Johansson B. Acute Lymphoblastic Leukaemia. In: Heim S, Mitelman F, (eds.) Cancer Cytogenetics. 3rd ed. New Jersey, USA: John Wiley and Son Inc; 2009.
    • (2009) Cancer Cytogenetics
    • Harrison, C.J.1    Johansson, B.2
  • 2
    • 77957361896 scopus 로고    scopus 로고
    • Detection of prognostically relevant genetic abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: Recommendations from the Biology and Diagnosis Committee of the International Berlin-Frankfurt- Munster study group
    • Harrison CJ, Haas O, Harbott J, Biondi A, Stanulla M, Trka J, et al. Detection of prognostically relevant genetic abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: recommendations from the Biology and Diagnosis Committee of the International Berlin-Frankfurt- Munster study group. Br J Haematol. 2010; 151(2):132-142.
    • (2010) Br J Haematol , vol.151 , Issue.2 , pp. 132-142
    • Harrison, C.J.1    Haas, O.2    Harbott, J.3    Biondi, A.4    Stanulla, M.5    Trka, J.6
  • 3
    • 34147224008 scopus 로고    scopus 로고
    • Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
    • Mullighan CG, Goorha S, Radtke I, Miller CB, Coustan-Smith E, Dalton JD, et al. Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature. 2007;446(7137):758-764.
    • (2007) Nature , vol.446 , Issue.7137 , pp. 758-764
    • Mullighan, C.G.1    Goorha, S.2    Radtke, I.3    Miller, C.B.4    Coustan-Smith, E.5    Dalton, J.D.6
  • 4
    • 34249733805 scopus 로고    scopus 로고
    • High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression
    • Kuiper RP, Schoenmakers EF, van Reijmersdal SV, Hehir-Kwa JY, van Kessel AG, van Leeuwen FN, et al. High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression. Leukemia. 2007;21(6):1258-1266.
    • (2007) Leukemia , vol.21 , Issue.6 , pp. 1258-1266
    • Kuiper, R.P.1    Schoenmakers, E.F.2    van Reijmersdal, S.V.3    Hehir-Kwa, J.Y.4    van Kessel, A.G.5    van Leeuwen, F.N.6
  • 5
    • 34249668665 scopus 로고    scopus 로고
    • Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization
    • Strefford JC, Worley H, Barber K, Wright S, Stewart AR, Robinson HM, et al. Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization. Oncogene. 2007;26 (29):4306-4318.
    • (2007) Oncogene , vol.26 , Issue.29 , pp. 4306-4318
    • Strefford, J.C.1    Worley, H.2    Barber, K.3    Wright, S.4    Stewart, A.R.5    Robinson, H.M.6
  • 7
    • 43049139905 scopus 로고    scopus 로고
    • BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
    • Mullighan CG, Miller CB, Radtke I, Phillips LA, Dalton J, Ma J, et al. BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature. 2008;453(7191): 110-114.
    • (2008) Nature , vol.453 , Issue.7191 , pp. 110-114
    • Mullighan, C.G.1    Miller, C.B.2    Radtke, I.3    Phillips, L.A.4    Dalton, J.5    Ma, J.6
  • 8
    • 70449719091 scopus 로고    scopus 로고
    • IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: A GIMEMA AL WP report
    • Martinelli G, Iacobucci I, Storlazzi CT, Vignetti M, Paoloni F, Cilloni D, et al. IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report. J Clin Oncol. 2009;27(31):5202-5207.
    • (2009) J Clin Oncol , vol.27 , Issue.31 , pp. 5202-5207
    • Martinelli, G.1    Iacobucci, I.2    Storlazzi, C.T.3    Vignetti, M.4    Paoloni, F.5    Cilloni, D.6
  • 9
    • 79751538993 scopus 로고    scopus 로고
    • Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts 79% of relapses in pediatric acute lymphoblastic leukemia
    • Waanders E, van der Velden VH, van der Schoot CE, van Leeuwen FN, van Reijmersdal SV, de Haas V, et al. Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts 79% of relapses in pediatric acute lymphoblastic leukemia. Leukemia. 2011;25 (2):254-258
    • (2011) Leukemia , vol.25 , Issue.2 , pp. 254-258
    • Waanders, E.1    van der Velden, V.H.2    van der Schoot, C.E.3    van Leeuwen, F.N.4    van Reijmersdal, S.V.5    de Haas, V.6
  • 11
    • 70349242044 scopus 로고    scopus 로고
    • Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCRABL1- positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute Leukemia Working Party (GIMEMA AL WP)
    • Iacobucci I, Storlazzi CT, Cilloni D, Lonetti A, Ottaviani E, Soverini S, et al. Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCRABL1- positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute Leukemia Working Party (GIMEMA AL WP). Blood. 2009;114(10):2159-2167.
    • (2009) Blood , vol.114 , Issue.10 , pp. 2159-2167
    • Iacobucci, I.1    Storlazzi, C.T.2    Cilloni, D.3    Lonetti, A.4    Ottaviani, E.5    Soverini, S.6
  • 12
    • 70350519430 scopus 로고    scopus 로고
    • Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia
    • Russell LJ, Capasso M, Vater I, Akasaka T, Bernard OA, Calasanz MJ, et al. Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia. Blood. 2009;114(13):2688-2698.
    • (2009) Blood , vol.114 , Issue.13 , pp. 2688-2698
    • Russell, L.J.1    Capasso, M.2    Vater, I.3    Akasaka, T.4    Bernard, O.A.5    Calasanz, M.J.6
  • 13
    • 77954516863 scopus 로고    scopus 로고
    • Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia
    • Harvey RC, Mullighan CG, Chen IM, Wharton W, Mikhail FM, Carroll AJ, et al. Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia. Blood. 2010;115 (26):5312-5321.
    • (2010) Blood , vol.115 , Issue.26 , pp. 5312-5321
    • Harvey, R.C.1    Mullighan, C.G.2    Chen, I.M.3    Wharton, W.4    Mikhail, F.M.5    Carroll, A.J.6
  • 14
    • 77954500629 scopus 로고    scopus 로고
    • Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALLBFM 2000 protocol
    • Cario G, Zimmermann M, Romey R, Gesk S, Vater I, Harbott J, et al. Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALLBFM 2000 protocol. Blood. 2010;115(26): 5393-5397.
    • (2010) Blood , vol.115 , Issue.26 , pp. 5393-5397
    • Cario, G.1    Zimmermann, M.2    Romey, R.3    Gesk, S.4    Vater, I.5    Harbott, J.6
  • 15
    • 79951845044 scopus 로고    scopus 로고
    • Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and CRLF2 deregulation: Results from the MRC ALL97 clinical trial
    • Ensor HM, Schwab C, Russell LJ, Richards SM, Morrison H, Masic D, et al. Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and CRLF2 deregulation: results from the MRC ALL97 clinical trial. Blood. 2011;117(7):2129-2136.
    • (2011) Blood , vol.117 , Issue.7 , pp. 2129-2136
    • Ensor, H.M.1    Schwab, C.2    Russell, L.J.3    Richards, S.M.4    Morrison, H.5    Masic, D.6
  • 16
    • 79551707478 scopus 로고    scopus 로고
    • Evaluation of multiplex ligation-dependent probe amplification as a method for the detection of copy number abnormalities in B-cell precursor acute lymphoblastic leukemia
    • Schwab CJ, Jones LR, Morrison H, Ryan SL, Yigittop H, Schouten JP, et al. Evaluation of multiplex ligation-dependent probe amplification as a method for the detection of copy number abnormalities in B-cell precursor acute lymphoblastic leukemia. Genes, Chromosomes Cancer. 2010;49(12):1104-1113.
    • (2010) Genes, Chromosomes Cancer , vol.49 , Issue.12 , pp. 1104-1113
    • Schwab, C.J.1    Jones, L.R.2    Morrison, H.3    Ryan, S.L.4    Yigittop, H.5    Schouten, J.P.6
  • 17
    • 33749515604 scopus 로고    scopus 로고
    • Toxicity and efficacy of 6-thioguanine versus 6-mercaptopurine in childhood lymphoblastic leukaemia: A randomised trial
    • Vora A, Mitchell CD, Lennard L, Eden TO, Kinsey SE, Lilleyman J, et al. Toxicity and efficacy of 6-thioguanine versus 6-mercaptopurine in childhood lymphoblastic leukaemia: a randomised trial. Lancet. 2006;368(9544):1339-1348.
    • (2006) Lancet , vol.368 , Issue.9544 , pp. 1339-1348
    • Vora, A.1    Mitchell, C.D.2    Lennard, L.3    Eden, T.O.4    Kinsey, S.E.5    Lilleyman, J.6
  • 18
    • 77950809859 scopus 로고    scopus 로고
    • Asparaginase-related venous thrombosis in UKALL 2003- re-exposure to asparaginase is feasible and safe
    • Qureshi A, Mitchell C, Richards S, Vora A, Goulden N. Asparaginase-related venous thrombosis in UKALL 2003- re-exposure to asparaginase is feasible and safe. Br J Haematol. 2010;149(3):410-413.
    • (2010) Br J Haematol , vol.149 , Issue.3 , pp. 410-413
    • Qureshi, A.1    Mitchell, C.2    Richards, S.3    Vora, A.4    Goulden, N.5
  • 19
    • 33947131584 scopus 로고    scopus 로고
    • Intrachromosomal amplification of chromosome 21 (iAMP21) may arise from a breakage-fusion-bridge cycle
    • Robinson HM, Harrison CJ, Moorman AV, Chudoba I, Strefford JC. Intrachromosomal amplification of chromosome 21 (iAMP21) may arise from a breakage-fusion-bridge cycle. Genes, Chromosomes Cancer. 2007;46(4):318-326.
    • (2007) Genes, Chromosomes Cancer , vol.46 , Issue.4 , pp. 318-326
    • Robinson, H.M.1    Harrison, C.J.2    Moorman, A.V.3    Chudoba, I.4    Strefford, J.C.5
  • 20
    • 77952305440 scopus 로고    scopus 로고
    • Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: Results from the UK Medical Research Council ALL97/99 randomised trial
    • Moorman AV, Ensor HM, Richards SM, Chilton L, Schwab C, Kinsey SE, et al. Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial. Lancet Oncol. 2010;11(5):429-438.
    • (2010) Lancet Oncol , vol.11 , Issue.5 , pp. 429-438
    • Moorman, A.V.1    Ensor, H.M.2    Richards, S.M.3    Chilton, L.4    Schwab, C.5    Kinsey, S.E.6
  • 21
    • 84865745212 scopus 로고    scopus 로고
    • IGH@ translocations, CRLF2 deregulation and micro-deletions in adolescents and adults with acute lymphoblastic leukemia (ALL)
    • Moorman AV, Schwab C, Ensor HM, Russell LJ, Morrison H, Jones L, et al. IGH@ translocations, CRLF2 deregulation and micro-deletions in adolescents and adults with acute lymphoblastic leukemia (ALL). J Clin Oncol. 2012;30(25):3100-3108.
    • (2012) J Clin Oncol , vol.30 , Issue.25 , pp. 3100-3108
    • Moorman, A.V.1    Schwab, C.2    Ensor, H.M.3    Russell, L.J.4    Morrison, H.5    Jones, L.6
  • 22
    • 58149095544 scopus 로고    scopus 로고
    • Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia
    • Harrison CJ. Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia. Br J Haematol. 2009;144(2):147-156.
    • (2009) Br J Haematol , vol.144 , Issue.2 , pp. 147-156
    • Harrison, C.J.1
  • 23
    • 55749102434 scopus 로고    scopus 로고
    • Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: Implications for a new mechanism of resistance
    • Iacobucci I, Lonetti A, Messa F, Cilloni D, Arruga F, Ottaviani E, et al. Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance. Blood. 2008;112 (9):3847-3855.
    • (2008) Blood , vol.112 , Issue.9 , pp. 3847-3855
    • Iacobucci, I.1    Lonetti, A.2    Messa, F.3    Cilloni, D.4    Arruga, F.5    Ottaviani, E.6
  • 24
    • 55949125130 scopus 로고    scopus 로고
    • Variable breakpoints target PAX5 in patients with dicentric chromosomes: A model for the basis of unbalanced translocations in cancer
    • An Q, Wright SL, Konn ZJ, Matheson E, Minto L, Moorman AV, et al. Variable breakpoints target PAX5 in patients with dicentric chromosomes: a model for the basis of unbalanced translocations in cancer. Proc Natl Acad Sci USA. 2008;105(44):17050-17054.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.44 , pp. 17050-17054
    • An, Q.1    Wright, S.L.2    Konn, Z.J.3    Matheson, E.4    Minto, L.5    Moorman, A.V.6
  • 25
    • 70450255241 scopus 로고    scopus 로고
    • PAX5 mutations occur frequently in adult Bcell progenitor acute lymphoblastic leukemia and PAX5 haploinsufficiency is associated with BCR-ABL1 and TCF3-PBX1 fusion genes: A GRAALL study
    • Familiades J, Bousquet M, Lafage-Pochitaloff M, Bene MC, Beldjord K, De Vos J, et al. PAX5 mutations occur frequently in adult Bcell progenitor acute lymphoblastic leukemia and PAX5 haploinsufficiency is associated with BCR-ABL1 and TCF3-PBX1 fusion genes: a GRAALL study. Leukemia. 2009;23(11):1989-1998.
    • (2009) Leukemia , vol.23 , Issue.11 , pp. 1989-1998
    • Familiades, J.1    Bousquet, M.2    Lafage-Pochitaloff, M.3    Bene, M.C.4    Beldjord, K.5    de Vos, J.6
  • 26
    • 0037702860 scopus 로고    scopus 로고
    • PAX5/ETV6 fusion defines cytogenetic entity dic(9;12)(p13;p13)
    • Strehl S, Konig M, Dworzak MN, Kalwak K, Haas OA. PAX5/ETV6 fusion defines cytogenetic entity dic(9;12)(p13;p13). Leukemia. 2003;17(6):1121-1123.
    • (2003) Leukemia , vol.17 , Issue.6 , pp. 1121-1123
    • Strehl, S.1    Konig, M.2    Dworzak, M.N.3    Kalwak, K.4    Haas, O.A.5
  • 27
    • 64649088311 scopus 로고    scopus 로고
    • High-resolution genomic profiling of pediatric lymphoblastic lymphomas reveals subtle differences with pediatric acute lymphoblastic leukemias in the B-lineage
    • Schraders M, van Reijmersdal SV, Kamping EJ, van Krieken JH, van Kessel AG, Groenen PJ, et al. High-resolution genomic profiling of pediatric lymphoblastic lymphomas reveals subtle differences with pediatric acute lymphoblastic leukemias in the B-lineage. Cancer Genet Cytogen. 2009;191 (1):27-33.
    • (2009) Cancer Genet Cytogen , vol.191 , Issue.1 , pp. 27-33
    • Schraders, M.1    van Reijmersdal, S.V.2    Kamping, E.J.3    van Krieken, J.H.4    van Kessel, A.G.5    Groenen, P.J.6
  • 28
    • 70350680415 scopus 로고    scopus 로고
    • Rearrangement of CRLF2 in B-progenitorand Down syndrome-associated acute lymphoblastic leukemia
    • Mullighan CG, Collins-Underwood JR, Phillips LA, Loudin MG, Liu W, Zhang J, et al. Rearrangement of CRLF2 in B-progenitorand Down syndrome-associated acute lymphoblastic leukemia. Nat Genet. 2009;41 (11):1243-1246.
    • (2009) Nat Genet , vol.41 , Issue.11 , pp. 1243-1246
    • Mullighan, C.G.1    Collins-Underwood, J.R.2    Phillips, L.A.3    Loudin, M.G.4    Liu, W.5    Zhang, J.6
  • 29
    • 84859820034 scopus 로고    scopus 로고
    • Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: A Children's Oncology Group study
    • Chen IM, Harvey RC, Mullighan CG, Gastier-Foster J, Wharton W, Kang H, et al. Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study. Blood. 2012;119(15):3512-3522.
    • (2012) Blood , vol.119 , Issue.15 , pp. 3512-3522
    • Chen, I.M.1    Harvey, R.C.2    Mullighan, C.G.3    Gastier-Foster, J.4    Wharton, W.5    Kang, H.6
  • 30
    • 77649214639 scopus 로고    scopus 로고
    • Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group
    • Hertzberg L, Vendramini E, Ganmore I, Cazzaniga G, Schmitz M, Chalker J, et al. Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group. Blood. 2010;115(5):1006-1017.
    • (2010) Blood , vol.115 , Issue.5 , pp. 1006-1017
    • Hertzberg, L.1    Vendramini, E.2    Ganmore, I.3    Cazzaniga, G.4    Schmitz, M.5    Chalker, J.6
  • 31
    • 77949425065 scopus 로고    scopus 로고
    • Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia
    • Chapiro E, Russell L, Lainey E, Kaltenbach S, Ragu C, Della-Valle V, et al. Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia. Leukemia. 2010;24 (3):642-645.
    • (2010) Leukemia , vol.24 , Issue.3 , pp. 642-645
    • Chapiro, E.1    Russell, L.2    Lainey, E.3    Kaltenbach, S.4    Ragu, C.5    Della-Valle, V.6
  • 32
    • 79959510774 scopus 로고    scopus 로고
    • Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia
    • Rand V, Parker H, Russell LJ, Schwab C, Ensor H, Irving J, et al. Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia. Blood. 2011;117(25):6848-6855.
    • (2011) Blood , vol.117 , Issue.25 , pp. 6848-6855
    • Rand, V.1    Parker, H.2    Russell, L.J.3    Schwab, C.4    Ensor, H.5    Irving, J.6
  • 33
    • 58149394484 scopus 로고    scopus 로고
    • Integration of genomic and gene expression data of childhood ALL without known aberrations identifies subgroups with specific genetic hallmarks
    • Bungaro S, Dell'Orto MC, Zangrando A, Basso D, Gorletta T, Lo Nigro L, et al. Integration of genomic and gene expression data of childhood ALL without known aberrations identifies subgroups with specific genetic hallmarks. Genes Chromosomes Cancer. 2009;48(1):22-38.
    • (2009) Genes Chromosomes Cancer , vol.48 , Issue.1 , pp. 22-38
    • Bungaro, S.1    Dell'orto, M.C.2    Zangrando, A.3    Basso, D.4    Gorletta, T.5    Lo Nigro, L.6
  • 34
    • 84859209595 scopus 로고    scopus 로고
    • The clinical relevance of chromosomal and genomic abnormalities in Bcell precursor acute lymphoblastic leukaemia
    • Moorman AV. The clinical relevance of chromosomal and genomic abnormalities in Bcell precursor acute lymphoblastic leukaemia. Blood Rev. 2012;26(3):123-135.
    • (2012) Blood Rev , vol.26 , Issue.3 , pp. 123-135
    • Moorman, A.V.1
  • 35
    • 61549114444 scopus 로고    scopus 로고
    • Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia
    • Yang JJ, Bhojwani D, Yang W, Cai X, Stocco G, Crews K, et al. Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia. Blood. 2008;112 (10):4178-4183.
    • (2008) Blood , vol.112 , Issue.10 , pp. 4178-4183
    • Yang, J.J.1    Bhojwani, D.2    Yang, W.3    Cai, X.4    Stocco, G.5    Crews, K.6
  • 36
    • 84873567677 scopus 로고    scopus 로고
    • Prognostic value of genetic alterations in children with first bone marrow relapse of childhood B-cell precursor acute lymphoblastic leukemia
    • Krentz S, Hof J, Mendioroz A, Vaggopoulou R, Dorge P, Lottaz C, et al. Prognostic value of genetic alterations in children with first bone marrow relapse of childhood B-cell precursor acute lymphoblastic leukemia. Leukemia. 2013;27(2):295-304.
    • (2013) Leukemia , vol.27 , Issue.2 , pp. 295-304
    • Krentz, S.1    Hof, J.2    Mendioroz, A.3    Vaggopoulou, R.4    Dorge, P.5    Lottaz, C.6
  • 38
    • 84859193076 scopus 로고    scopus 로고
    • The origin and nature of tightly clustered BTG1 deletions in precursor B-cell acute lymphoblastic leukemia support a model of multiclonal evolution
    • Waanders E, Scheijen B, van der Meer LT, van Reijmersdal SV, van Emst L, Kroeze Y, et al. The origin and nature of tightly clustered BTG1 deletions in precursor B-cell acute lymphoblastic leukemia support a model of multiclonal evolution. PLoS Genet. 2012; 8(2):e1002533.
    • (2012) PLoS Genet , vol.8 , Issue.2
    • Waanders, E.1    Scheijen, B.2    van der Meer, L.T.3    van Reijmersdal, S.V.4    van Emst, L.5    Kroeze, Y.6
  • 39
    • 77954719755 scopus 로고    scopus 로고
    • BTG1 regulates glucocorticoid receptor autoinduction in acute lymphoblastic leukemia
    • van Galen JC, Kuiper RP, van Emst L, Levers M, Tijchon E, Scheijen B, et al. BTG1 regulates glucocorticoid receptor autoinduction in acute lymphoblastic leukemia. Blood. 2010;115(23):4810-4819.
    • (2010) Blood , vol.115 , Issue.23 , pp. 4810-4819
    • van Galen, J.C.1    Kuiper, R.P.2    van Emst, L.3    Levers, M.4    Tijchon, E.5    Scheijen, B.6
  • 41
    • 0141634051 scopus 로고    scopus 로고
    • Origins of chromosome translocations in childhood leukaemia
    • Greaves MF, Wiemels J. Origins of chromosome translocations in childhood leukaemia. Nature Reviews. 2003;3(9):639-649.
    • (2003) Nature Reviews , vol.3 , Issue.9 , pp. 639-649
    • Greaves, M.F.1    Wiemels, J.2
  • 42


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