-
1
-
-
84899623290
-
The clinical profile and pathophysiology of atrial fibrillation: Relationships among clinical features, epidemiology, and mechanisms
-
Andrade J, Khairy P, Dobrev D, Nattel S. The clinical profile and pathophysiology of atrial fibrillation: relationships among clinical features, epidemiology, and mechanisms. Circ Res. 2014;114:1453-1468. doi: 10.1161/CIRCRESAHA.114.303211.
-
(2014)
Circ Res
, vol.114
, pp. 1453-1468
-
-
Andrade, J.1
Khairy, P.2
Dobrev, D.3
Nattel, S.4
-
3
-
-
0038037760
-
Familial atrial fibrillation is a genetically heterogeneous disorder
-
Darbar D, Herron KJ, Ballew JD, Jahangir A, Gersh BJ, Shen WK, Hammill SC, Packer DL, Olson TM. Familial atrial fibrillation is a genetically heterogeneous disorder. J Am Coll Cardiol. 2003;41:2185-2192.
-
(2003)
J Am Coll Cardiol
, vol.41
, pp. 2185-2192
-
-
Darbar, D.1
Herron, K.J.2
Ballew, J.D.3
Jahangir, A.4
Gersh, B.J.5
Shen, W.K.6
Hammill, S.C.7
Packer, D.L.8
Olson, T.M.9
-
4
-
-
84865528698
-
Familial aggregation of lone atrial fibrillation in young persons
-
Oyen N, Ranthe MF, Carstensen L, Boyd HA, Olesen MS, Olesen SP, Wohlfahrt J, Melbye M. Familial aggregation of lone atrial fibrillation in young persons. J Am Coll Cardiol. 2012;60:917-921. doi: 10.1016/j. jacc.2012.03.046.
-
(2012)
J Am Coll Cardiol
, vol.60
, pp. 917-921
-
-
Oyen, N.1
Ranthe, M.F.2
Carstensen, L.3
Boyd, H.A.4
Olesen, M.S.5
Olesen, S.P.6
Wohlfahrt, J.7
Melbye, M.8
-
5
-
-
84881257862
-
Novel genetic markers improve measures of atrial fibrillation risk prediction
-
Everett BM, Cook NR, Conen D, Chasman DI, Ridker PM, Albert CM. Novel genetic markers improve measures of atrial fibrillation risk prediction. Eur Heart J. 2013;34:2243-2251. doi: 10.1093/eurheartj/eht033.
-
(2013)
Eur Heart J
, vol.34
, pp. 2243-2251
-
-
Everett, B.M.1
Cook, N.R.2
Conen, D.3
Chasman, D.I.4
Ridker, P.M.5
Albert, C.M.6
-
6
-
-
84922480103
-
Twelve-single nucleotide polymorphism genetic risk score identifies individuals at increased risk for future atrial fibrillation and stroke
-
Tada H, Shiffman D, Smith JG, Sjogren M, Lubitz SA, Ellinor PT, Louie JZ, Catanese JJ, Engstrom G, Devlin JJ, Kathiresan S, Melander O. Twelve-single nucleotide polymorphism genetic risk score identifies individuals at increased risk for future atrial fibrillation and stroke. Stroke. 2014;45:2856-2862. doi: 10.1161/STROKEAHA.114.006072.
-
(2014)
Stroke
, vol.45
, pp. 2856-2862
-
-
Tada, H.1
Shiffman, D.2
Smith, J.G.3
Sjogren, M.4
Lubitz, S.A.5
Ellinor, P.T.6
Louie, J.Z.7
Catanese, J.J.8
Engstrom, G.9
Devlin, J.J.10
Kathiresan, S.11
Melander, O.12
-
7
-
-
0037428218
-
KCNQ1 gain-of-function mutation in familial atrial fibrillation
-
Chen YH, Xu SJ, Bendahhou S, Wang XL, Wang Y, Xu WY, Jin HW, Sun H, Su XY, Zhuang QN, Yang YQ, Li YB, Liu Y, Xu HJ, Li XF, Ma N, Mou CP, Chen Z, Barhanin J, Huang W. KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science. 2003;299:251-254.
-
(2003)
Science
, vol.299
, pp. 251-254
-
-
Chen, Y.H.1
Xu, S.J.2
Bendahhou, S.3
Wang, X.L.4
Wang, Y.5
Xu, W.Y.6
Jin, H.W.7
Sun, H.8
Su, X.Y.9
Zhuang, Q.N.10
Yang, Y.Q.11
Li, Y.B.12
Liu, Y.13
Xu, H.J.14
Li, X.F.15
Ma, N.16
Mou, C.P.17
Chen, Z.18
Barhanin, J.19
Huang, W.20
more..
-
8
-
-
84894387715
-
Atrial fibrillation: The role of common and rare genetic variants
-
Olesen MS, Nielsen MW, Haunso S, Svendsen JH. Atrial fibrillation: the role of common and rare genetic variants. Eur J Hum Genet. 2014;22:297-306. doi: 10.1038/ejhg.2013.139.
-
(2014)
Eur J Hum Genet
, vol.22
, pp. 297-306
-
-
Olesen, M.S.1
Nielsen, M.W.2
Haunso, S.3
Svendsen, J.H.4
-
9
-
-
84899657011
-
Emerging directions in the genetics of atrial fibrillation
-
Tucker NR, Ellinor PT. Emerging directions in the genetics of atrial fibrillation. Circ Res. 2014;114:1469-1482. doi: 10.1161/CIRCRESAHA.114.302225.
-
(2014)
Circ Res
, vol.114
, pp. 1469-1482
-
-
Tucker, N.R.1
Ellinor, P.T.2
-
10
-
-
84879087735
-
Genetic mechanisms of atrial fibrillation: Impact on response to treatment
-
Darbar D, Roden DM. Genetic mechanisms of atrial fibrillation: impact on response to treatment. Nat Rev Cardiol. 2013;10:317-329. doi: 10.1038/nrcardio.2013.53.
-
(2013)
Nat Rev Cardiol
, vol.10
, pp. 317-329
-
-
Darbar, D.1
Roden, D.M.2
-
11
-
-
84944679904
-
-
NHLBI Exome Sequencing Project (ESP) . Accessed January 02
-
NHLBI Exome Sequencing Project (ESP). Exome Variant Server Web site. http://evs.gs.washington.edu/EVS/. Accessed January 02, 2015.
-
(2015)
Exome Variant Server Web Site
-
-
-
12
-
-
84944714412
-
-
ExAC Browser (Beta)|Exome Aggregation Consortium. Accessed January 02
-
ExAC Browser (Beta)|Exome Aggregation Consortium Website. http://exac.broadinstitute.org/. Accessed January 02, 2015.
-
(2015)
-
-
-
13
-
-
70350528745
-
Long QT syndrome and associated gene mutation carriers in Japanese children: Results from ECG screening examinations
-
Hayashi K, Fujino N, Uchiyama K, Ino H, Sakata K, Konno T, Masuta E, Funada A, Sakamoto Y, Tsubokawa T, Nakashima K, Liu L, Higashida H, Hiramaru Y, Shimizu M, Yamagishi M. Long QT syndrome and associated gene mutation carriers in Japanese children: results from ECG screening examinations. Clin Sci (Lond). 2009;117:415-424. doi: 10.1042/CS20080528.
-
(2009)
Clin Sci (Lond)
, vol.117
, pp. 415-424
-
-
Hayashi, K.1
Fujino, N.2
Uchiyama, K.3
Ino, H.4
Sakata, K.5
Konno, T.6
Masuta, E.7
Funada, A.8
Sakamoto, Y.9
Tsubokawa, T.10
Nakashima, K.11
Liu, L.12
Higashida, H.13
Hiramaru, Y.14
Shimizu, M.15
Yamagishi, M.16
-
14
-
-
84868615791
-
Phylogenetic and physicochemical analyses enhance the classification of rare nonsynonymous single nucleotide variants in type 1 and 2 long-QT syndrome
-
Giudicessi JR, Kapplinger JD, Tester DJ, Alders M, Salisbury BA, Wilde AA, Ackerman MJ. Phylogenetic and physicochemical analyses enhance the classification of rare nonsynonymous single nucleotide variants in type 1 and 2 long-QT syndrome. Circ Cardiovasc Genet. 2012;5:519-528. doi: 10.1161/CIRCGENETICS.112.963785.
-
(2012)
Circ Cardiovasc Genet
, vol.5
, pp. 519-528
-
-
Giudicessi, J.R.1
Kapplinger, J.D.2
Tester, D.J.3
Alders, M.4
Salisbury, B.A.5
Wilde, A.A.6
Ackerman, M.J.7
-
15
-
-
84867301515
-
Predicting the functional effect of amino acid substitutions and indels
-
Choi Y, Sims GE, Murphy S, Miller JR, Chan AP. Predicting the functional effect of amino acid substitutions and indels. PLoS One. 2012;7:e46688. doi: 10.1371/journal.pone.0046688.
-
(2012)
PLoS One
, vol.7
, pp. e46688
-
-
Choi, Y.1
Sims, G.E.2
Murphy, S.3
Miller, J.R.4
Chan, A.P.5
-
16
-
-
84895858942
-
A general framework for estimating the relative pathogenicity of human genetic variants
-
Kircher M, Witten DM, Jain P, O'Roak BJ, Cooper GM, Shendure J. A general framework for estimating the relative pathogenicity of human genetic variants. Nat Genet. 2014;46:310-315. doi: 10.1038/ng.2892.
-
(2014)
Nat Genet
, vol.46
, pp. 310-315
-
-
Kircher, M.1
Witten, D.M.2
Jain, P.3
O'Roak, B.J.4
Cooper, G.M.5
Shendure, J.6
-
17
-
-
84893069849
-
Very early-onset lone atrial fibrillation patients have a high prevalence of rare variants in genes previously associated with atrial fibrillation
-
Olesen MS, Andreasen L, Jabbari J, Refsgaard L, Haunso S, Olesen SP, Nielsen JB, Schmitt N, Svendsen JH. Very early-onset lone atrial fibrillation patients have a high prevalence of rare variants in genes previously associated with atrial fibrillation. Heart Rhythm. 2014;11:246-251. doi: 10.1016/j.hrthm.2013.10.034.
-
(2014)
Heart Rhythm
, vol.11
, pp. 246-251
-
-
Olesen, M.S.1
Andreasen, L.2
Jabbari, J.3
Refsgaard, L.4
Haunso, S.5
Olesen, S.P.6
Nielsen, J.B.7
Schmitt, N.8
Svendsen, J.H.9
-
18
-
-
84878295837
-
Genetic variation in KCNA5: Impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation
-
Christophersen IE, Olesen MS, Liang B, Andersen MN,Larsen AP, Nielsen JB, Haunso S, Olesen SP, Tveit A, Svendsen JH, Schmitt N. Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation. Eur Heart J. 2013;34:1517-1525. doi: 10.1093/eurheartj/ehs442.
-
(2013)
Eur Heart J
, vol.34
, pp. 1517-1525
-
-
Christophersen, I.E.1
Olesen, M.S.2
Liang, B.3
Andersen, M.N.4
Larsen, A.P.5
Nielsen, J.B.6
Haunso, S.7
Olesen, S.P.8
Tveit, A.9
Svendsen, J.H.10
Schmitt, N.11
-
19
-
-
67649536037
-
Novel KCNA5 loss-of-function mutations responsible for atrial fibrillation
-
Yang Y, Li J, Lin X, Yang Y, Hong K, Wang L, Liu J, Li L, Yan D, Liang D, Xiao J, Jin H, Wu J, Zhang Y, Chen YH. Novel KCNA5 loss-of-function mutations responsible for atrial fibrillation. J Hum Genet. 2009;54:277-283. doi: 10.1038/jhg.2009.26.
-
(2009)
J Hum Genet
, vol.54
, pp. 277-283
-
-
Yang, Y.1
Li, J.2
Lin, X.3
Yang, Y.4
Hong, K.5
Wang, L.6
Liu, J.7
Li, L.8
Yan, D.9
Liang, D.10
Xiao, J.11
Jin, H.12
Wu, J.13
Zhang, Y.14
Chen, Y.H.15
-
21
-
-
0033514263
-
Low penetrance in the long-QT syndrome: Clinical impact
-
Priori SG, Napolitano C, Schwartz PJ. Low penetrance in the long-QT syndrome: clinical impact. Circulation. 1999;99:529-533.
-
(1999)
Circulation
, vol.99
, pp. 529-533
-
-
Priori, S.G.1
Napolitano, C.2
Schwartz, P.J.3
-
22
-
-
55849115645
-
Cardiac ion channel gene mutations in sudden infant death syndrome
-
Otagiri T, Kijima K, Osawa M, Ishii K, Makita N, Matoba R, Umetsu K, Hayasaka K. Cardiac ion channel gene mutations in sudden infant death syndrome. Pediatr Res. 2008;64:482-487. doi: 10.1203/PDR.0b013e3181841eca.
-
(2008)
Pediatr Res
, vol.64
, pp. 482-487
-
-
Otagiri, T.1
Kijima, K.2
Osawa, M.3
Ishii, K.4
Makita, N.5
Matoba, R.6
Umetsu, K.7
Hayasaka, K.8
-
23
-
-
70349451838
-
Mutations in sodium channel beta1-and beta2-subunits associated with atrial fibrillation
-
Watanabe H, Darbar D, Kaiser DW, Jiramongkolchai K, Chopra S, Donahue BS, Kannankeril PJ, Roden DM. Mutations in sodium channel beta1-and beta2-subunits associated with atrial fibrillation. Circ Arrhythm Electrophysiol. 2009;2:268-275. doi: 10.1161/CIRCEP.108.779181.
-
(2009)
Circ Arrhythm Electrophysiol
, vol.2
, pp. 268-275
-
-
Watanabe, H.1
Darbar, D.2
Kaiser, D.W.3
Jiramongkolchai, K.4
Chopra, S.5
Donahue, B.S.6
Kannankeril, P.J.7
Roden, D.M.8
-
24
-
-
68049143486
-
In silico investigations on functional and haplotype tag SNPs associated with congenital long QT syndromes (LQTSs)
-
Sudandiradoss C, Sethumadhavan R. In silico investigations on functional and haplotype tag SNPs associated with congenital long QT syndromes (LQTSs). Genomic Med. 2008;2:55-67. doi: 10.1007/s11568-009-9027-3.
-
(2008)
Genomic Med
, vol.2
, pp. 55-67
-
-
Sudandiradoss, C.1
Sethumadhavan, R.2
-
25
-
-
84902301776
-
New population-based exome data question the pathogenicity of some genetic variants previously associated with Marfan syndrome
-
Yang RQ, Jabbari J, Cheng XS, Jabbari R, Nielsen JB, Risgaard B, Chen X, Sajadieh A, Haunso S, Svendsen JH, Olesen MS, Tfelt-Hansen J. New population-based exome data question the pathogenicity of some genetic variants previously associated with Marfan syndrome. BMC Genet. 2014;15:74. doi: 10.1186/1471-2156-15-74.
-
(2014)
BMC Genet
, vol.15
, pp. 74
-
-
Yang, R.Q.1
Jabbari, J.2
Cheng, X.S.3
Jabbari, R.4
Nielsen, J.B.5
Risgaard, B.6
Chen, X.7
Sajadieh, A.8
Haunso, S.9
Svendsen, J.H.10
Olesen, M.S.11
Tfelt-Hansen, J.12
-
26
-
-
84891514824
-
Selective targeting of gain-of-function KCNQ1 mutations predisposing to atrial fibrillation
-
Campbell CM, Campbell JD, Thompson CH, Galimberti ES, Darbar D, Vanoye CG, George AL Jr. Selective targeting of gain-of-function KCNQ1 mutations predisposing to atrial fibrillation. Circ Arrhythm Electrophysiol. 2013;6:960-966. doi: 10.1161/CIRCEP.113.000439.
-
(2013)
Circ Arrhythm Electrophysiol
, vol.6
, pp. 960-966
-
-
Campbell, C.M.1
Campbell, J.D.2
Thompson, C.H.3
Galimberti, E.S.4
Darbar, D.5
Vanoye, C.G.6
George, A.L.7
-
27
-
-
84863230453
-
Epistatic effects of potassium channel variation on cardiac repolarization and atrial fibrillation risk
-
Mann SA, Otway R, Guo G,Soka M, Karlsdotter L, Trivedi G, Ohanian M, Zodgekar P, Smith RA, Wouters MA, Subbiah R, Walker B, Kuchar D, Sanders P, Griffiths L, Vandenberg JI, Fatkin D. Epistatic effects of potassium channel variation on cardiac repolarization and atrial fibrillation risk. J Am Coll Cardiol. 2012;59:1017-1025. doi: 10.1016/j.jacc.2011.11.039.
-
(2012)
J Am Coll Cardiol
, vol.59
, pp. 1017-1025
-
-
Mann, S.A.1
Otway, R.2
Guo, G.3
Soka, M.4
Karlsdotter, L.5
Trivedi, G.6
Ohanian, M.7
Zodgekar, P.8
Smith, R.A.9
Wouters, M.A.10
Subbiah, R.11
Walker, B.12
Kuchar, D.13
Sanders, P.14
Griffiths, L.15
Vandenberg, J.I.16
Fatkin, D.17
|