Disrupted sleep: From molecules to cognition

Journal of Neuroscience

Volumn 35, Issue 41, 2015, Pages 13889-13895

  Van Someren, Eus J W ^a,b   Cirelli, Chiara ^c   Dijk, Derk Jan ^d   Van Cauter, Eve ^e   Schwartz, Sophie ^f   Chee, Michael W L ^g  

^a NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d UNIVERSITY OF SURREY   (United Kingdom)

^e UNIVERSITY OF CHICAGO   (United States)

^f UNIVERSITY OF GENEVA   (Switzerland)

^g DUKE NUS MEDICAL SCHOOL   (Singapore)

Author keywords

Cellular ultrastructure; Gene expression; Insomnia; Metabolism; Mood; Sleep disruption

Indexed keywords

GHRELIN; LEPTIN; NORADRENALIN; THYROXINE;

ALERTNESS; APPETITE DISORDER; ARTICLE; BRAIN CELL; CARDIOVASCULAR DISEASE; CELL ULTRASTRUCTURE; CIRCADIAN RHYTHM; COGNITION; DEPRESSION; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENE EXPRESSION; HEART RATE VARIABILITY; HORMONE SYNTHESIS; HUMAN; INSOMNIA; METABOLIC REGULATION; METABOLISM; MOOD; NERVE DEGENERATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; REWARD; SLEEP DEPRIVATION; SLEEP TIME; AFFECT; BRAIN; COGNITION DISORDERS; COMPLICATION; PATHOLOGY; PHYSIOLOGY; SLEEP WAKE DISORDERS;

AFFECT; BRAIN; COGNITION DISORDERS; HUMANS; SLEEP WAKE DISORDERS;

EID: 84944524861     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2592-15.2015     Document Type: Article

References (85)

1. Altena E, Vrenken H, van der Werf YD, van den Heuvel OAV, Van Someren EJ (2010) Reduced orbitofrontal and parietal grey matter in chronic insomnia: a voxel-based morphometric study. Biol Psychiatry 67:182-185. CrossRef Medline
2. Archer SN, Oster H (2015) How sleep and wakefulness influence circadian rhythmicity: effects of insufficient and mistimed sleep on the animal and human transcriptome. J Sleep Res. In press.
3. Archer SN, Laing EE, Möller-Levet CS, van der Veen DR, Bucca G, Lazar AS, Santhi N, Slak A, Kabiljo R, von Schantz M, Smith CP, Dijk DJ (2014) Mistimed sleep disrupts circadian regulation of the human transcriptome. Proc Natl Acad Sci U S A 111:E682-E691. CrossRef Medline
4. Astill RG, Van der Heijden KB, Van IJzendoorn MH, Van Someren EJ (2012) Sleep, cognition and behavioral problems in school-aged children: A century of research meta-analyzed. Psychol Bull 138:1109-1138. CrossRef Medline
5. Bassetti C, Ferini Strambi L, Brown S, Adamantidis A, Benedetti F, Bruni O, Cajochen C, Dolenc-Groselj L, Ferri R, Gais S, Huber R, Khatami R, Lammers GJ, Luppi PH, Peigneux P, Pollmächer T, Randerath W, Riemann D, Santamaria J, Schindler K, Tafti M, Van Someren EJ, Wetter TC (2015) Neurology and psychiatry: waking up to opportunities of sleep. Eur J Neurol. In press. CrossRef Medline
6. Boomsma DI, van Someren EJ, Beem AL, de Geus EJ, Willemsen G (2008) Sleep during a regular week night: a twin-sibling study. Twin Res Hum Genet 11:538-545. CrossRef Medline
7. Borbély AA, Achermann P (1999) Sleep homeostasis and models of sleep regulation. J Biol Rhythms 14:557-568. Medline
8. Buysse DJ, Cheng Y, Germain A, Moul DE, Franzen PL, Fletcher M, Monk TH (2010) Night-to-night sleep variability in older adults with and without chronic insomnia. Sleep Med 11:56-64. CrossRef Medline
9. Caldwell JA, Mu Q, Smith JK, Mishory A, Caldwell JL, Peters G, Brown DL, George MS (2005) Are individual differences in fatigue vulnerability related to baseline differences in cortical activation? Behav Neurosci 119: 694-707. CrossRef Medline
10. Chee MW (2014) Limitations on visual information processing in the sleepdeprived brain and their underlying mechanisms. Curr Opin Behav Sci 1:56-63.
11. Chee MW, Chuah LY, Venkatraman V, Chan WY, Philip P, Dinges DF (2006) Functional imaging of working memory following normal sleep and after 24 and 35 hours of sleep deprivation: Correlations of frontoparietal activation with performance. Neuroimage 31:419-428. CrossRef Medline
12. Chua EC, Yeo SC, Lee IT, Tan LC, Lau P, Tan SS, Ho Mien I, Gooley JJ (2014a) Individual differences in physiologic measures are stable across repeated exposures to total sleep deprivation. Physol Rep 2:e12129. CrossRef Medline
13. Chua EC, Yeo SC, Lee IT, Tan LC, Lau P, Cai S, Zhang X, Puvanendran K, Gooley JJ (2014b) Sustained attention performance during sleep deprivation associates with instability in behavior and physiologic measures at baseline. Sleep 37:27-39. Medline
14. Cirelli C (2009) The genetic and molecular regulation of sleep: from fruit flies to humans. Nat Rev Neurosci 10:549-560. CrossRef Medline
15. Cirelli C, Tononi G (2008) Is sleep essential? PLoS Biol 6:e216. CrossRef Medline
16. De Havas JA, Parimal S, Soon CS, Chee MW (2012) Sleep deprivation reduces default mode network connectivity and anti-correlation during rest and task performance. Neuroimage 59:1745-1751. CrossRef Medline
17. Deurveilher S, Bush JE, Rusak B, Eskes GA, Semba K (2015) Psychomotor vigilance task performance during and following chronic sleep restriction in rats. Sleep 38:515-528. Medline
18. Diaz BA, Van Der Sluis S, Moens S, Benjamins JS, Migliorati F, Stoffers D, Den Braber A, Poil SS, Hardstone R, Van’t Ent D, Boomsma DI, De Geus E, Mansvelder HD, Van Someren EJ, Linkenkaer-Hansen K (2013) The Amsterdam Resting-State Questionnaire reveals multiple phenotypes of resting-state cognition. Front Hum Neurosci 7:446. Medline
19. Dijk DJ, Czeisler CA (1995) Contribution of the circadian pacemaker and the sleep homeostat to sleep propensity, sleep structure, electroencephalographic slow waves, and sleep spindle activity in humans. J Neurosci 15:3526-3538. Medline
20. Djonlagic I, Saboisky J, Carusona A, Stickgold R, Malhotra A (2012) Increased sleep fragmentation leads to impaired off-line consolidation of motor memories in humans. PLoS One 7:e34106. CrossRef Medline
21. Everson CA (1993) Sustained sleep deprivation impairs host defense. Am J Physiol 265:R1148-R1154. Medline
22. Feige B, Baglioni C, Spiegelhalder K, Hirscher V, Nissen C, Riemann D (2013) The microstructure of sleep in primary insomnia: an overview and extension. Int J Psychophysiol 89:171-180. CrossRef Medline
23. Feld GB, Besedovsky L, Kaida K, Mu¨nte TF, Born J (2014) Dopamine D2-like receptor activation wipes out preferential consolidation of high over low reward memories during human sleep. J Cogn Neurosci 26:2310-2320. CrossRef Medline
24. Gustavsson A, Svensson M, Jacobi F, Allgulander C, Alonso J, Beghi E, Dodel R, Ekman M, Faravelli C, Fratiglioni L, Gannon B, Jones DH, Jennum P, Jordanova A, Jönsson L, Karampampa K, Knapp M, Kobelt G, Kurth T, Lieb R, et al; CDBE2010 Study Group (2011) Cost of disorders of the brain in Europe 2010. Eur Neuropsychopharmacol 21:718-779. CrossRef Medline
25. Harvey CJ, Gehrman P, Espie CA (2014) Who is predisposed to insomnia: a review of familial aggregation, stress-reactivity, personality and coping style. Sleep Med Rev 18:237-247. CrossRef Medline
26. Horikawa T, Tamaki M, Miyawaki Y, Kamitani Y (2013) Neural decoding of visual imagery during sleep. Science 340:639-642. CrossRef Medline
27. Kim Y, Laposky AD, Bergmann BM, Turek FW (2007) Repeated sleep restriction in rats leads to homeostatic and allostatic responses during recovery sleep. Proc Natl Acad Sci U S A 104:10697-10702. CrossRef Medline
28. Landolt HP (2008) Genotype-dependent differences in sleep, vigilance, and response to stimulants. Curr Pharm Des 14:3396-3407. CrossRef Medline
29. Lansink CS, Goltstein PM, Lankelma JV, McNaughton BL, Pennartz CM (2009) Hippocampus leads ventral striatum in replay of place-reward information. PLoS Biol 7:e1000173. CrossRef Medline
30. Lazar AS, Lazar ZI, Dijk DJ (2015) Circadian regulation of slow waves in human sleep: topographical aspects. Neuroimage 116:123-134. CrossRef Medline
31. Leemburg S, Vyazovskiy VV, Olcese U, Bassetti CL, Tononi G, Cirelli C (2010) Sleep homeostasis in the rat is preserved during chronic sleep restriction. Proc Natl Acad SciUS 107:15939-15944. CrossRef Medline
32. Lim J, Dinges DF (2010) A meta-analysis of the impact of short-term sleep deprivation on cognitive variables. Psychol Bull 136:375-389. CrossRef Medline
33. Lo JC, Groeger JA, Santhi N, Arbon EL, Lazar AS, Hasan S, von Schantz M, Archer SN, Dijk DJ (2012) Effects of partial and acute total sleep deprivation on performance across cognitive domains, individuals and circadian phase. PLoS One 7:e45987. CrossRef Medline
34. Luik AI, Zuurbier LA, Hofman A, Van Someren EJ, Ikram MA, Tiemeier H (2015a) Associations of the 24-hour activity rhythm and sleep with cognition: A population-based study of middle-aged and elderly persons. Sleep Med 16:850-855. CrossRef Medline
35. Luik AI, Zuurbier LA, Direk N, Hofman A, Van Someren EJ, Tiemeier H (2015b) 24-hour activity rhythm and sleep disturbances in depression and anxiety: a population-based study of middle-aged and older persons. Depress Anxiety. In press.
36. Maret S, Dorsaz S, Gurcel L, Pradervand S, Petit B, Pfister C, Hagenbuchle O, O’Hara BF, Franken P, Tafti M (2007) Homer1a is a core brain molecular correlate of sleep loss. Proc Natl Acad Sci U S A 104:20090-20095. CrossRef Medline
37. Markwald RR, Melanson EL, Smith MR, Higgins J, Perreault L, Eckel RH, Wright KP Jr (2013) Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain. Proc Natl Acad Sci U S A 110: 5695-5700. CrossRef Medline
38. Möller-Levet CS, Archer SN, Bucca G, Laing EE, Slak A, Kabiljo R, Lo JC, Santhi N, von Schantz M, Smith CP, Dijk DJ (2013) Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome. Proc Natl Acad SciU S A 110:E1132-E1141. CrossRef Medline
39. Mu Q, Nahas Z, Johnson KA, Yamanaka K, Mishory A, Koola J, Hill S, Horner MD, Bohning DE, George MS (2005) Decreased cortical response to verbal working memory following sleep deprivation. Sleep 28:55-67. Medline
40. Nedeltcheva AV, Scheer FA (2014) Metabolic effects of sleep disruption, links to obesity and diabetes. Curr Opin Endocrinol Diabetes Obes 21: 293-298. CrossRef Medline
41. Oudiette D, Antony JW, Creery JD, Paller KA (2013) The role of memory reactivation during wakefulness and sleep in determining which memories endure. J Neurosci 33:6672-6678. CrossRef Medline
42. Owens J; Adolescent Sleep Working Group; Committee on Adolescence (2014) Insufficient sleep in adolescents and young adults: an update on causes and consequences. Pediatrics 134:e921-e932. CrossRef Medline
43. Palagini L, Biber K, Riemann D (2014) The genetics of insomnia-evidence for epigenetic mechanisms? Sleep Med Rev 18:225-235. CrossRef Medline
44. Partch CL, Green CB, Takahashi JS (2014) Molecular architecture of the mammalian circadian clock. Trends Cell Biol 24:90-99. CrossRef Medline
45. Patanaik A, Zagorodnov V, Kwoh CK, Chee MW (2014) Predicting vulnerability to sleep deprivation using diffusion model parameters. J Sleep Res 23:576-584. CrossRef Medline
46. Patanaik A, Kwoh CK, Chua EC, Gooley JJ, Chee MW (2015) Classifying vulnerability to sleep deprivation using baseline measures of psychomotor vigilance. Sleep 38:723-734. Medline
47. Perogamvros L, Schwartz S (2012) The roles of the reward system in sleep and dreaming. Neurosci Biobehav Rev 36:1934-1951. CrossRef Medline
48. Perogamvros L, Schwartz S (2015) Sleep and emotional functions. Curr Top Behav Neurosci 25:411-431. Medline
49. Piantoni G, Poil SS, Linkenkaer-Hansen K, Verweij IM, Ramautar JR, Van Someren EJ, van der Werf YD (2013) Individual differences in white matter diffusion affect sleep oscillations. J Neurosci 33:227-233. CrossRef Medline
50. Rasch B, Born J (2013) About sleep’s role in memory. Physiol Rev 93:681-766. CrossRef Medline
51. Ratcliff R, Van Dongen HP (2011) Diffusion model for one-choice reaction-time tasks and the cognitive effects of sleep deprivation. Proc Natl Acad Sci U S A 108:11285-11290. CrossRef Medline
52. Raymann RJ, Van Someren EJ (2008) Diminished capability to recognize the optimal temperature for sleep initiation may contribute to poor sleep in elderly people. Sleep 31:1301-1309. Medline
53. Rechtschaffen A, Bergmann BM (2002) Sleep deprivation in the rat: an update of the 1989 paper. Sleep 25:18-24. Medline
54. Rechtschaffen A, Bergmann BM, Everson CA, Kushida CA, Gilliland MA (1989) Sleep deprivation in the rat: X. Integration and discussion of the findings. Sleep 12:68-87. Medline
55. Reutrakul S, Van Cauter E (2014) Interactions between sleep, circadian function, and glucose metabolism: implications for risk and severity of diabetes. Ann NY Acad Sci 1311:151-173. CrossRef Medline
56. Rupp TL, Wesensten NJ, Balkin TJ (2012) Trait-like vulnerability to total and partial sleep loss. Sleep 35:1163-1172. Medline
57. Sämann PG, Tully C, Spoormaker VI, Wetter TC, Holsboer F, Wehrle R, Czisch M (2010) Increased sleep pressure reduces resting state functional connectivity. MAGMA 23:375-389. CrossRef Medline
58. Sämann PG, Wehrle R, Hoehn D, Spoormaker VI, Peters H, Tully C, Holsboer F, Czisch M (2011) Development of the brain’s default mode network from wakefulness to slow wave sleep. Cereb Cortex 21:2082-2093. CrossRef Medline
59. Siegel JM (2012) Evolution: suppression of sleep for mating. Science 337: 1610-1611. CrossRef Medline
60. Singer AC, Frank LM (2009) Rewarded outcomes enhance reactivation of experience in the hippocampus. Neuron 64:910-921. CrossRef Medline
61. Stamatakis KA, Punjabi NM (2010) Effects of sleep fragmentation on glucose metabolism in normal subjects. Chest 137:95-101. CrossRef Medline
62. Stoffers D, Moens S, Benjamins J, van Tol MJ, Penninx BW, Veltman DJ, Van der Wee NJA, Van Someren EJ (2012) Orbitofrontal gray matter relates to early morning awakening: a neural correlate of insomnia complaints? Front Neurol 3:105. Medline
63. Stoffers D, Altena E, van der Werf YD, Sanz-Arigita EJ, Voorn TA, Astill RG, Strijers RL, Waterman D, Van Someren EJ (2014) The caudate: a key node in the neuronal network imbalance of insomnia? Brain 137:610-620. CrossRef Medline
64. Swaab DF, Van Someren EJ, Zhou JN, Hofman MA (1996) Biological rhythms in the human life cycle and their relationship to functional changes in the suprachiasmatic nucleus. Prog Brain Res 111:349-368. CrossRef Medline
65. Tasali E, Leproult R, Ehrmann DA, Van Cauter E (2008) Slow-wave sleep and the risk of type 2 diabetes in humans. Proc Natl Acad Sci U S A 105:1044-1049. CrossRef Medline
66. Tononi G, Cirelli C (2014) Sleep and the price of plasticity: from synaptic and cellular homeostasis to memory consolidation and integration. Neuron 81:12-34. CrossRef Medline
67. Vallieres A, Ivers H, Bastien CH, Beaulieu-Bonneau S, Morin CM (2005) Variability and predictability in sleep patterns of chronic insomniacs. J Sleep Res 14:447-453. CrossRef Medline
68. van der Werf YD, Altena E, Schoonheim MM, Sanz-Arigita EJ, Vis JC, De Rijke W, Van Someren EJ (2009) Sleep benefits subsequent hippocampal functioning. Nat Neurosci 12:122-123. CrossRef Medline
69. van der Werf YD, Altena E, van Dijk KD, Strijers RL, De Rijke W, Stam CJ, van Someren EJ (2010) Is disturbed intracortical excitability a stable trait of chronic insomnia? A study using transcranial magnetic stimulation before and after multimodal sleep therapy. Biol Psychiatry 68:950-955. CrossRef Medline
70. Van Dongen HP, Baynard MD, Maislin G, Dinges DF (2004) Systematic interindividual differences in neurobehavioral impairment from sleep loss: evidence of trait-like differential vulnerability. Sleep 27:423-433. Medline
71. Van Someren EJ (2007) Improving actigraphic sleep estimates: how many nights? J Sleep Res 16:269-275. CrossRef Medline
72. Van Someren EJ (2010) Doing with less sleep remains a dream. Proc Natl Acad Sci U S A 107:16003-16004. CrossRef Medline
73. Van Someren EJ, Riemersma-Van Der Lek RF (2007) Live to the rhythm, slave to the rhythm. Sleep Med Rev 11:465-484. CrossRef Medline
74. Van Someren EJ, Benjamins J, Stoffers D, Hoekstra T, Migliorati F, Van Tol M-J, Twisk JWR (2014) Brain structure and large-scale psychometrics point to different subtypes of insomnia. Soc Neurosci Abstr 40:676.12
75. Vanderheyden WM, Poe GR, Liberzon I (2014) Trauma exposure and sleep: using a rodent model to understand sleep function in PTSD. Exp Brain Res 232:1575-1584. CrossRef Medline
76. Varga AW, Kishi A, Mantua J, Lim J, Koushyk V, Leibert DP, Osorio RS, Rapoport DM, Ayappa I (2014) Apnea-induced rapid eye movement sleep disruption impairs human spatial navigational memory. J Neurosci 34:14571-14577. CrossRef Medline
77. Venkatraman V, Huettel SA, Chuah LY, Payne JW, Chee MW (2011) Sleep deprivation biases the neural mechanisms underlying economic preferences. J Neurosci 31:3712-3718. CrossRef Medline
78. Wilhelm I, Diekelmann S, Molzow I, Ayoub A, Mölle M, Born J (2011) Sleep selectively enhances memory expected to be of future relevance. J Neurosci 31:1563-1569. CrossRef Medline
79. Wittchen HU, Jacobi F, Rehm J, Gustavsson A, Svensson M, Jönsson B, Olesen J, Allgulander C, Alonso J, Faravelli C, Fratiglioni L, Jennum P, Lieb R, Maercker A, van Os J, Preisig M, Salvador-Carulla L, Simon R, Steinhausen HC (2011) The size and burden of mental disorders and other disorders of the brain in Europe 2010. Eur Neuropsychopharmacol 21:655-679. CrossRef Medline
80. Xie L, Kang H, Xu Q, Chen MJ, Liao Y, Thiyagarajan M, O’Donnell J, Christensen DJ, Nicholson C, Iliff JJ, Takano T, Deane R, Nedergaard M (2013) Sleep drives metabolite clearance from the adult brain. Science 342:373-377. CrossRef Medline
81. Yeo BT, Tandi J, Chee MW (2015) Functional connectivity during rested wakefulness predicts vulnerability to sleep deprivation. Neuroimage 111: 147-158. CrossRef Medline
82. Zhang R, Lahens NF, Ballance HI, Hughes ME, Hogenesch JB (2014) A circadian gene expression atlas in mammals: implications for biology and medicine. Proc Natl Acad Sci U S A 111:16219-16224. CrossRef Medline
83. Zhu Y, Fenik P, Zhan G, Xin R, Veasey SC (2015) Degeneration in arousal neurons in chronic sleep disruption modeling sleep apnea. Front Neurol 6:109. Medline
84. Zuurbier LA, Luik AI, Hofman A, Franco OH, Van Someren EJ, Tiemeier H (2015a) Fragmentation and stability of circadian activity rhythms predict mortality: The Rotterdam Study. Am J Epidemiol 181:54-63. CrossRef Medline
85. Zuurbier LA, Ikram MA, Luik AI, Hofman A, Van Someren EJ, Vernooij MW, Tiemeier H (2015b) Cerebral small vessel disease is related to disturbed 24-hour activity rhythms: a population-based study. Eur J Neurol. In press.