-
1
-
-
84859768494
-
Molecular targeted therapy in acute myeloid leukemia
-
Daver N, Cortes J. Molecular targeted therapy in acute myeloid leukemia. Hematology. 2012; 17:S59-62.
-
(2012)
Hematology.
, vol.17
, pp. S59-62
-
-
Daver, N.1
Cortes, J.2
-
2
-
-
84873524967
-
PARP-1 mechanism for coupling DNA damage detection to poly(ADP-ribose) synthesis
-
Langelier MF, Pascal JM. PARP-1 mechanism for coupling DNA damage detection to poly(ADP-ribose) synthesis. Curr Opin Struct Biol. 2013; 23:134-143.
-
(2013)
Curr Opin Struct Biol.
, vol.23
, pp. 134-143
-
-
Langelier, M.F.1
Pascal, J.M.2
-
4
-
-
84886719040
-
PARP-1 and gene regulation: progress and puzzles
-
Kraus WL, Hottiger MO. PARP-1 and gene regulation: progress and puzzles. Mol Aspects Med. 2013; 34:1109-1123.
-
(2013)
Mol Aspects Med.
, vol.34
, pp. 1109-1123
-
-
Kraus, W.L.1
Hottiger, M.O.2
-
5
-
-
0034731455
-
Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins
-
Pleschke JM, Kleczkowska HE, Strohm M, Althaus FR. Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins. J Biol Chem. 2000; 275:40974-40980.
-
(2000)
J Biol Chem.
, vol.275
, pp. 40974-40980
-
-
Pleschke, J.M.1
Kleczkowska, H.E.2
Strohm, M.3
Althaus, F.R.4
-
6
-
-
84885604912
-
Variations in the mRNA expression of poly(ADP-ribose) polymerases, poly(ADP-ribose) glycohydrolase and ADP-ribosylhydrolase 3 in breast tumors and impact on clinical outcome
-
Bieche I, Pennaneach V, Driouch K, Vacher S, Zaremba T, Susini A, Lidereau R, Hall J. Variations in the mRNA expression of poly(ADP-ribose) polymerases, poly(ADP-ribose) glycohydrolase and ADP-ribosylhydrolase 3 in breast tumors and impact on clinical outcome. Int J Cancer. 2013; 133:2791-2800.
-
(2013)
Int J Cancer.
, vol.133
, pp. 2791-2800
-
-
Bieche, I.1
Pennaneach, V.2
Driouch, K.3
Vacher, S.4
Zaremba, T.5
Susini, A.6
Lidereau, R.7
Hall, J.8
-
7
-
-
0034074057
-
Enhancement of poly-adenosine diphosphate-ribosylation in human hepatocellular carcinoma
-
Nomura F, Yaguchi M, Togawa A, Miyazaki M, Isobe K, Miyake M, Noda M, Nakai T. Enhancement of poly-adenosine diphosphate-ribosylation in human hepatocellular carcinoma. J Gastroenterol Hepatol. 2000; 15:529-535.
-
(2000)
J Gastroenterol Hepatol.
, vol.15
, pp. 529-535
-
-
Nomura, F.1
Yaguchi, M.2
Togawa, A.3
Miyazaki, M.4
Isobe, K.5
Miyake, M.6
Noda, M.7
Nakai, T.8
-
8
-
-
84958034121
-
PARP1 is overexpressed in nasopharyngeal carcinoma and its inhibition enhances radiotherapy
-
Chow JP, Man WY, Mao M, Chen H, Cheung F, Nicholls J, Tsao SW, Li Lung M, Poon RY. PARP1 is overexpressed in nasopharyngeal carcinoma and its inhibition enhances radiotherapy. Mol Cancer Ther. 2013; 12:2517-2528.
-
(2013)
Mol Cancer Ther.
, vol.12
, pp. 2517-2528
-
-
Chow, J.P.1
Man, W.Y.2
Mao, M.3
Chen, H.4
Cheung, F.5
Nicholls, J.6
Tsao, S.W.7
Li Lung, M.8
Poon, R.Y.9
-
9
-
-
84858957528
-
Nuclear PARP-1 protein overexpression is associated with poor overall survival in early breast cancer
-
Rojo F, Garcia-Parra J, Zazo S, Tusquets I, Ferrer-Lozano J, Menendez S, Eroles P, Chamizo C, Servitja S, Ramirez-Merino N, Lobo F, Bellosillo B, Corominas JM, Yelamos J, Serrano S, Lluch A, et al. Nuclear PARP-1 protein overexpression is associated with poor overall survival in early breast cancer. Ann Oncol. 2012; 23:1156-1164.
-
(2012)
Ann Oncol.
, vol.23
, pp. 1156-1164
-
-
Rojo, F.1
Garcia-Parra, J.2
Zazo, S.3
Tusquets, I.4
Ferrer-Lozano, J.5
Menendez, S.6
Eroles, P.7
Chamizo, C.8
Servitja, S.9
Ramirez-Merino, N.10
Lobo, F.11
Bellosillo, B.12
Corominas, J.M.13
Yelamos, J.14
Serrano, S.15
Lluch, A.16
-
10
-
-
67749099823
-
Poly(adenosine diphosphate-ribose) polymerase-1 expression in cutaneous malignant melanomas as a new molecular marker of aggressive tumor
-
Csete B, Lengyel Z, Kadar Z, Battyani Z. Poly(adenosine diphosphate-ribose) polymerase-1 expression in cutaneous malignant melanomas as a new molecular marker of aggressive tumor. Pathol Oncol Res. 2009; 15:47-53.
-
(2009)
Pathol Oncol Res.
, vol.15
, pp. 47-53
-
-
Csete, B.1
Lengyel, Z.2
Kadar, Z.3
Battyani, Z.4
-
11
-
-
84868444460
-
The PARP inhibitor PJ34 modifies proliferation, NIS expression and epigenetic marks in thyroid cancer cell lines
-
Lavarone E, Puppin C, Passon N, Filetti S, Russo D, Damante G. The PARP inhibitor PJ34 modifies proliferation, NIS expression and epigenetic marks in thyroid cancer cell lines. Mol Cell Endocrinol. 2013; 365:1-10.
-
(2013)
Mol Cell Endocrinol.
, vol.365
, pp. 1-10
-
-
Lavarone, E.1
Puppin, C.2
Passon, N.3
Filetti, S.4
Russo, D.5
Damante, G.6
-
12
-
-
84879677739
-
PARP-1 regulates metastatic melanoma through modulation of vimentin-induced malignant transformation
-
Rodriguez MI, Peralta-Leal A, O'Valle F, Rodriguez-Vargas JM, Gonzalez-Flores A, Majuelos-Melguizo J, Lopez L, Serrano S, de Herreros AG, Rodriguez-Manzaneque JC, Fernandez R, Del Moral RG, de Almodovar JM, Oliver FJ. PARP-1 regulates metastatic melanoma through modulation of vimentin-induced malignant transformation. PLoS Genet. 2013; 9:e1003531.
-
(2013)
PLoS Genet.
, vol.9
-
-
Rodriguez, M.I.1
Peralta-Leal, A.2
O'Valle, F.3
Rodriguez-Vargas, J.M.4
Gonzalez-Flores, A.5
Majuelos-Melguizo, J.6
Lopez, L.7
Serrano, S.8
de Herreros, A.G.9
Rodriguez-Manzaneque, J.C.10
Fernandez, R.11
Del Moral, R.G.12
de Almodovar, J.M.13
Oliver, F.J.14
-
13
-
-
84883469199
-
PARP-1 regulates resistance of pancreatic cancer to TRAIL therapy
-
Yuan K, Sun Y, Zhou T, McDonald J, Chen Y. PARP-1 regulates resistance of pancreatic cancer to TRAIL therapy. Clin Cancer Res. 2013; 19:4750-4759.
-
(2013)
Clin Cancer Res.
, vol.19
, pp. 4750-4759
-
-
Yuan, K.1
Sun, Y.2
Zhou, T.3
McDonald, J.4
Chen, Y.5
-
14
-
-
0026684707
-
Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily
-
Vigon I, Mornon JP, Cocault L, Mitjavila MT, Tambourin P, Gisselbrecht S, Souyri M. Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily. Proc Natl Acad Sci U S A. 1992; 89:5640-5644.
-
(1992)
Proc Natl Acad Sci U S A.
, vol.89
, pp. 5640-5644
-
-
Vigon, I.1
Mornon, J.P.2
Cocault, L.3
Mitjavila, M.T.4
Tambourin, P.5
Gisselbrecht, S.6
Souyri, M.7
-
15
-
-
22044447126
-
Thrombopoietin and the hematopoietic stem cell
-
Kaushansky K. Thrombopoietin and the hematopoietic stem cell. Ann N Y Acad Sci. 2005; 1044:139-141.
-
(2005)
Ann N Y Acad Sci.
, vol.1044
, pp. 139-141
-
-
Kaushansky, K.1
-
16
-
-
84872776224
-
Different mutations of the human c-mpl gene indicate distinct haematopoietic diseases
-
He X, Chen Z, Jiang Y, Qiu X, Zhao X. Different mutations of the human c-mpl gene indicate distinct haematopoietic diseases. J Hematol Oncol. 2013; 6:11.
-
(2013)
J Hematol Oncol.
, vol.6
, pp. 11
-
-
He, X.1
Chen, Z.2
Jiang, Y.3
Qiu, X.4
Zhao, X.5
-
17
-
-
59949090392
-
Clinical significance of Gata-1, Gata-2, EKLF, and c-MPL expression in acute myeloid leukemia
-
Ayala RM, Martinez-Lopez J, Albizua E, Diez A, Gilsanz F. Clinical significance of Gata-1, Gata-2, EKLF, and c-MPL expression in acute myeloid leukemia. Am J Hematol. 2009; 84:79-86.
-
(2009)
Am J Hematol.
, vol.84
, pp. 79-86
-
-
Ayala, R.M.1
Martinez-Lopez, J.2
Albizua, E.3
Diez, A.4
Gilsanz, F.5
-
18
-
-
83255187529
-
Gadd45 stress sensors in malignancy and leukemia
-
Liebermann DA, Tront JS, Sha X, Mukherjee K, Mohamed-Hadley A, Hoffman B. Gadd45 stress sensors in malignancy and leukemia. Crit Rev Oncog. 2011; 16:129-140.
-
(2011)
Crit Rev Oncog.
, vol.16
, pp. 129-140
-
-
Liebermann, D.A.1
Tront, J.S.2
Sha, X.3
Mukherjee, K.4
Mohamed-Hadley, A.5
Hoffman, B.6
-
19
-
-
84904900099
-
Identification of target genes using gene expression profile of granulocytes from patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors
-
Mascarenhas CD, da Cunha AF, Brugnerotto AF, Gambero S, de Almeida MH, Carazzolle MF, Pagnano KBB, Traina F, da Costa FF, de Souza CA. Identification of target genes using gene expression profile of granulocytes from patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors. Leukemia & Lymphoma. 2014; 55:1861-1869.
-
(2014)
Leukemia & Lymphoma.
, vol.55
, pp. 1861-1869
-
-
Mascarenhas, C.D.1
da Cunha, A.F.2
Brugnerotto, A.F.3
Gambero, S.4
de Almeida, M.H.5
Carazzolle, M.F.6
Pagnano, K.B.B.7
Traina, F.8
da Costa, F.F.9
de Souza, C.A.10
-
20
-
-
84871794409
-
Src-Like adaptor protein (SLAP) binds to the receptor tyrosine kinase Flt3 and modulates receptor stability and downstream signaling
-
Kazi JU, Ronnstrand L. Src-Like adaptor protein (SLAP) binds to the receptor tyrosine kinase Flt3 and modulates receptor stability and downstream signaling. PLoS One. 2012; 7:e53509.
-
(2012)
PLoS One.
, vol.7
-
-
Kazi, J.U.1
Ronnstrand, L.2
-
21
-
-
84876041430
-
Transposon mutagenesis reveals cooperation of ETS family transcription factors with signaling pathways in erythro-megakaryocytic leukemia
-
Tang JZ, Carmichael CL, Shi W, Metcalf D, Ng AP, Hyland CD, Jenkins NA, Copeland NG, Howell VM, Zhao ZJ, Smyth GK, Kile BT, Alexander WS. Transposon mutagenesis reveals cooperation of ETS family transcription factors with signaling pathways in erythro-megakaryocytic leukemia. Proc Natl Acad Sci U S A. 2013; 110:6091-6096.
-
(2013)
Proc Natl Acad Sci U S A.
, vol.110
, pp. 6091-6096
-
-
Tang, J.Z.1
Carmichael, C.L.2
Shi, W.3
Metcalf, D.4
Ng, A.P.5
Hyland, C.D.6
Jenkins, N.A.7
Copeland, N.G.8
Howell, V.M.9
Zhao, Z.J.10
Smyth, G.K.11
Kile, B.T.12
Alexander, W.S.13
-
22
-
-
84864484317
-
Thrombopoietin/MPL participates in initiating and maintaining RUNX1-ETO acute myeloid leukemia via PI3K/AKT signaling
-
Pulikkan JA, Madera D, Xue L, Bradley P, Landrette SF, Kuo YH, Abbas S, Zhu LJ, Valk P, Castilla LH. Thrombopoietin/MPL participates in initiating and maintaining RUNX1-ETO acute myeloid leukemia via PI3K/AKT signaling. Blood. 2012; 120:868-879.
-
(2012)
Blood.
, vol.120
, pp. 868-879
-
-
Pulikkan, J.A.1
Madera, D.2
Xue, L.3
Bradley, P.4
Landrette, S.F.5
Kuo, Y.H.6
Abbas, S.7
Zhu, L.J.8
Valk, P.9
Castilla, L.H.10
-
23
-
-
84864448458
-
The thrombopoietin/MPL/Bcl-xL pathway is essential for survival and self-renewal in human preleukemia induced by AML1-ETO
-
Chou FS, Griesinger A, Wunderlich M, Lin S, Link KA, Shrestha M, Goyama S, Mizukawa B, Shen S, Marcucci G, Mulloy JC. The thrombopoietin/MPL/Bcl-xL pathway is essential for survival and self-renewal in human preleukemia induced by AML1-ETO. Blood. 2012; 120:709-719.
-
(2012)
Blood.
, vol.120
, pp. 709-719
-
-
Chou, F.S.1
Griesinger, A.2
Wunderlich, M.3
Lin, S.4
Link, K.A.5
Shrestha, M.6
Goyama, S.7
Mizukawa, B.8
Shen, S.9
Marcucci, G.10
Mulloy, J.C.11
-
24
-
-
84940229854
-
The TPO/c-MPL pathway in the bone marrow may protect leukemia cells from chemotherapy in AML patients
-
Dong-Feng Z, Ting L, Yong Z, Cheng C, Xi Z, Pei-Yan K. The TPO/c-MPL pathway in the bone marrow may protect leukemia cells from chemotherapy in AML patients. Pathol Oncol Res. 2014; 20:309-317.
-
(2014)
Pathol Oncol Res.
, vol.20
, pp. 309-317
-
-
Dong-Feng, Z.1
Ting, L.2
Yong, Z.3
Cheng, C.4
Xi, Z.5
Pei-Yan, K.6
-
25
-
-
0028302409
-
Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand
-
de Sauvage FJ, Hass PE, Spencer SD, Malloy BE, Gurney AL, Spencer SA, Darbonne WC, Henzel WJ, Wong SC, Kuang WJ, et al. Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature. 1994; 369:533-538.
-
(1994)
Nature.
, vol.369
, pp. 533-538
-
-
de Sauvage, F.J.1
Hass, P.E.2
Spencer, S.D.3
Malloy, B.E.4
Gurney, A.L.5
Spencer, S.A.6
Darbonne, W.C.7
Henzel, W.J.8
Wong, S.C.9
Kuang, W.J.10
-
26
-
-
0038468754
-
Thrombopoietin: accumulating evidence for an important biological effect on the hematopoietic stem cell
-
Kaushansky K. Thrombopoietin: accumulating evidence for an important biological effect on the hematopoietic stem cell. Ann N Y Acad Sci. 2003; 996:39-43.
-
(2003)
Ann N Y Acad Sci.
, vol.996
, pp. 39-43
-
-
Kaushansky, K.1
-
27
-
-
0032126638
-
Role of c-mpl in early hematopoiesis
-
Solar GP, Kerr WG, Zeigler FC, Hess D, Donahue C, de Sauvage FJ, Eaton DL. Role of c-mpl in early hematopoiesis. Blood. 1998; 92:4-10.
-
(1998)
Blood.
, vol.92
, pp. 4-10
-
-
Solar, G.P.1
Kerr, W.G.2
Zeigler, F.C.3
Hess, D.4
Donahue, C.5
de Sauvage, F.J.6
Eaton, D.L.7
-
28
-
-
73449100129
-
Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression
-
Quiles-Perez R, Munoz-Gamez JA, Ruiz-Extremera A, O'Valle F, Sanjuan-Nunez L, Martin-Alvarez AB, Martin-Oliva D, Caballero T, Munoz de Rueda P, Leon J, Gonzalez R, Muntane J, Oliver FJ, Salmeron J. Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression. Hepatology. 2010; 51:255-266.
-
(2010)
Hepatology.
, vol.51
, pp. 255-266
-
-
Quiles-Perez, R.1
Munoz-Gamez, J.A.2
Ruiz-Extremera, A.3
O'Valle, F.4
Sanjuan-Nunez, L.5
Martin-Alvarez, A.B.6
Martin-Oliva, D.7
Caballero, T.8
Munoz de Rueda, P.9
Leon, J.10
Gonzalez, R.11
Muntane, J.12
Oliver, F.J.13
Salmeron, J.14
-
29
-
-
79952852791
-
Upregulation of poly (ADP-ribose) polymerase-(PARP) in triple-negative breast cancer and other primary human tumor types
-
Ossovskaya V, Koo IC, Kaldjian EP, Alvares C, Sherman BM. Upregulation of poly (ADP-ribose) polymerase-(PARP) in triple-negative breast cancer and other primary human tumor types. Genes Cancer. 2010; 1:812-821.
-
(2010)
Genes Cancer.
, vol.1
, pp. 812-821
-
-
Ossovskaya, V.1
Koo, I.C.2
Kaldjian, E.P.3
Alvares, C.4
Sherman, B.M.5
-
30
-
-
16844378949
-
Changes in NAD/ADP-ribose metabolism in rectal cancer
-
Yalcintepe L, Turker-Sener L, Sener A, Yetkin G, Tiryaki D, Bermek E. Changes in NAD/ADP-ribose metabolism in rectal cancer. Braz J Med Biol Res. 2005; 38:361-365.
-
(2005)
Braz J Med Biol Res.
, vol.38
, pp. 361-365
-
-
Yalcintepe, L.1
Turker-Sener, L.2
Sener, A.3
Yetkin, G.4
Tiryaki, D.5
Bermek, E.6
-
31
-
-
54549112093
-
PJ34, an inhibitor of PARP-1, suppresses cell growth and enhances the suppressive effects of cisplatin in liver cancer cells
-
Huang SH, Xiong M, Chen XP, Xiao ZY, Zhao YF, Huang ZY. PJ34, an inhibitor of PARP-1, suppresses cell growth and enhances the suppressive effects of cisplatin in liver cancer cells. Oncology Reports. 2008; 20:567-572.
-
(2008)
Oncology Reports.
, vol.20
, pp. 567-572
-
-
Huang, S.H.1
Xiong, M.2
Chen, X.P.3
Xiao, Z.Y.4
Zhao, Y.F.5
Huang, Z.Y.6
-
32
-
-
27144458683
-
Cyclins and CDKS in development and cancer: lessons from genetically modified mice
-
Santamaria D, Ortega S. Cyclins and CDKS in development and cancer: lessons from genetically modified mice. Frontiers in Bioscience. 2006; 11:1164-1188.
-
(2006)
Frontiers in Bioscience.
, vol.11
, pp. 1164-1188
-
-
Santamaria, D.1
Ortega, S.2
-
33
-
-
0141502208
-
Downmodulation of ERK activity inhibits the proliferation and induces the apoptosis of primary acute myelogenous leukemia blasts
-
Lunghi P, Tabilio A, Dall'Aglio PP, Ridolo E, Carlo-Stella C, Pelicci PG, Bonati A. Downmodulation of ERK activity inhibits the proliferation and induces the apoptosis of primary acute myelogenous leukemia blasts. leukemia. 2003; 17:1783-1793.
-
(2003)
leukemia.
, vol.17
, pp. 1783-1793
-
-
Lunghi, P.1
Tabilio, A.2
Dall'Aglio, P.P.3
Ridolo, E.4
Carlo-Stella, C.5
Pelicci, P.G.6
Bonati, A.7
-
34
-
-
79960235543
-
Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy
-
Steelman LS, Franklin RA, Abrams SL, Chappell W, Kempf CR, Basecke J, Stivala F, Donia M, Fagone P, Nicoletti F, Libra M, Ruvolo P, Ruvolo V, Evangelisti C, Martelli AM, McCubrey JA. Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy. leukemia. 2011; 25:1080-1094.
-
(2011)
leukemia.
, vol.25
, pp. 1080-1094
-
-
Steelman, L.S.1
Franklin, R.A.2
Abrams, S.L.3
Chappell, W.4
Kempf, C.R.5
Basecke, J.6
Stivala, F.7
Donia, M.8
Fagone, P.9
Nicoletti, F.10
Libra, M.11
Ruvolo, P.12
Ruvolo, V.13
Evangelisti, C.14
Martelli, A.M.15
McCubrey, J.A.16
-
35
-
-
84893262127
-
PARP inhibitors for anticancer therapy
-
Curtin N. PARP inhibitors for anticancer therapy. Biochem Soc Trans. 2014; 42:82-88.
-
(2014)
Biochem Soc Trans.
, vol.42
, pp. 82-88
-
-
Curtin, N.1
-
36
-
-
84905251990
-
Inhibition of poly(ADP-ribosyl)ation in cancer: old and new paradigms revisited
-
Lupo B, Trusolino L. Inhibition of poly(ADP-ribosyl)ation in cancer: old and new paradigms revisited. Biochim Biophys Acta. 2014; 1846:201-215.
-
(2014)
Biochim Biophys Acta.
, vol.1846
, pp. 201-215
-
-
Lupo, B.1
Trusolino, L.2
-
37
-
-
79251564088
-
A review of PARP inhibitors: from bench to bedside
-
Underhill C, Toulmonde M, Bonnefoi H. A review of PARP inhibitors: from bench to bedside. Ann Oncol. 2011; 22:268-279.
-
(2011)
Ann Oncol.
, vol.22
, pp. 268-279
-
-
Underhill, C.1
Toulmonde, M.2
Bonnefoi, H.3
-
38
-
-
84886721124
-
Reprogramming cellular events by poly(ADP-ribose)-binding proteins
-
Krietsch J, Rouleau M, Pic E, Ethier C, Dawson TM, Dawson VL, Masson JY, Poirier GG, Gagne JP. Reprogramming cellular events by poly(ADP-ribose)-binding proteins. Molecular Aspects of Medicine. 2013; 34:1066-1087.
-
(2013)
Molecular Aspects of Medicine.
, vol.34
, pp. 1066-1087
-
-
Krietsch, J.1
Rouleau, M.2
Pic, E.3
Ethier, C.4
Dawson, T.M.5
Dawson, V.L.6
Masson, J.Y.7
Poirier, G.G.8
Gagne, J.P.9
-
39
-
-
84899494248
-
Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis
-
Mukhopadhyay P, Rajesh M, Cao Z, Horvath B, Park O, Wang H, Erdelyi K, Holovac E, Wang Y, Liaudet L, Hamdaoui N, Lafdil F, Hasko G, Szabo C, Boulares AH, Gao B, et al. Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis. Hepatology. 2014; 59:1998-2009.
-
(2014)
Hepatology.
, vol.59
, pp. 1998-2009
-
-
Mukhopadhyay, P.1
Rajesh, M.2
Cao, Z.3
Horvath, B.4
Park, O.5
Wang, H.6
Erdelyi, K.7
Holovac, E.8
Wang, Y.9
Liaudet, L.10
Hamdaoui, N.11
Lafdil, F.12
Hasko, G.13
Szabo, C.14
Boulares, A.H.15
Gao, B.16
-
40
-
-
84921911496
-
Activation of poly(ADP-ribose) polymerase-1 delays wound healing by regulating keratinocyte migration and production of inflammatory mediators
-
El-Hamoly T, Hegedus C, Lakatos P, Kovacs K, Bai P, El-Ghazaly MA, El-Denshary ES, Szabo E, Virag L. Activation of poly(ADP-ribose) polymerase-1 delays wound healing by regulating keratinocyte migration and production of inflammatory mediators. Mol Med. 2014; 20:363-371.
-
(2014)
Mol Med.
, vol.20
, pp. 363-371
-
-
El-Hamoly, T.1
Hegedus, C.2
Lakatos, P.3
Kovacs, K.4
Bai, P.5
El-Ghazaly, M.A.6
El-Denshary, E.S.7
Szabo, E.8
Virag, L.9
-
41
-
-
84879813578
-
Beyond DNA repair, the immunological role of PARP-1 and its siblings
-
Rosado MM, Bennici E, Novelli F, Pioli C. Beyond DNA repair, the immunological role of PARP-1 and its siblings. Immunology. 2013; 139:428-437.
-
(2013)
Immunology.
, vol.139
, pp. 428-437
-
-
Rosado, M.M.1
Bennici, E.2
Novelli, F.3
Pioli, C.4
-
42
-
-
84907961435
-
Parp-1 genetic ablation in Ela-myc mice unveils novel roles for Parp-1 in pancreatic cancer
-
Martinez-Bosch N, Iglesias M, Munne-Collado J, Martinez-Caceres C, Moreno M, Guerra C, Yelamos J, Navarro P. Parp-1 genetic ablation in Ela-myc mice unveils novel roles for Parp-1 in pancreatic cancer. J Pathol. 2014; 234:214-227.
-
(2014)
J Pathol.
, vol.234
, pp. 214-227
-
-
Martinez-Bosch, N.1
Iglesias, M.2
Munne-Collado, J.3
Martinez-Caceres, C.4
Moreno, M.5
Guerra, C.6
Yelamos, J.7
Navarro, P.8
-
43
-
-
84864676959
-
The guanine-quadruplex structure in the human c-myc gene's promoter is converted into B-DNA form by the human poly(ADP-Ribose)polymerase-1
-
Fekete A, Kenesi E, Hunyadi-Gulyas E, Durgo H, Berko B, Dunai ZA, Bauer PI. The guanine-quadruplex structure in the human c-myc gene's promoter is converted into B-DNA form by the human poly(ADP-Ribose)polymerase-1. PLoS One. 2012; 7:e42690.
-
(2012)
PLoS One.
, vol.7
-
-
Fekete, A.1
Kenesi, E.2
Hunyadi-Gulyas, E.3
Durgo, H.4
Berko, B.5
Dunai, Z.A.6
Bauer, P.I.7
-
44
-
-
0029960265
-
Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl
-
Alexander WS, Roberts AW, Nicola NA, Li R, Metcalf D. Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl. Blood. 1996; 87:2162-2170.
-
(1996)
Blood.
, vol.87
, pp. 2162-2170
-
-
Alexander, W.S.1
Roberts, A.W.2
Nicola, N.A.3
Li, R.4
Metcalf, D.5
-
45
-
-
79954464525
-
The thrombopoietin/MPL pathway in hematopoiesis and leukemogenesis
-
Chou FS, Mulloy JC. The thrombopoietin/MPL pathway in hematopoiesis and leukemogenesis. J Cell Biochem. 2011; 112:1491-1498.
-
(2011)
J Cell Biochem.
, vol.112
, pp. 1491-1498
-
-
Chou, F.S.1
Mulloy, J.C.2
-
46
-
-
84891456126
-
Expression of c-MPL in leukemic stem cells from acute myeloid leukemia patients
-
Yu P, Qiu SW, Rao Q, Lin D, Xing HY, Tang KJ, Tian Z, Wang M, Wang JX. Expression of c-MPL in leukemic stem cells from acute myeloid leukemia patients. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2012; 20:1052-1055.
-
(2012)
Zhongguo Shi Yan Xue Ye Xue Za Zhi.
, vol.20
, pp. 1052-1055
-
-
Yu, P.1
Qiu, S.W.2
Rao, Q.3
Lin, D.4
Xing, H.Y.5
Tang, K.J.6
Tian, Z.7
Wang, M.8
Wang, J.X.9
-
47
-
-
0027257805
-
Expression of the c-mpl proto-oncogene in human hematologic malignancies
-
Vigon I, Dreyfus F, Melle J, Viguie F, Ribrag V, Cocault L, Souyri M, Gisselbrecht S. Expression of the c-mpl proto-oncogene in human hematologic malignancies. Blood. 1993; 82:877-883.
-
(1993)
Blood.
, vol.82
, pp. 877-883
-
-
Vigon, I.1
Dreyfus, F.2
Melle, J.3
Viguie, F.4
Ribrag, V.5
Cocault, L.6
Souyri, M.7
Gisselbrecht, S.8
-
48
-
-
84893875673
-
Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation
-
Bluteau D, Balduini A, Balayn N, Currao M, Nurden P, Deswarte C, Leverger G, Noris P, Perrotta S, Solary E, Vainchenker W, Debili N, Favier R, Raslova H. Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation. J Clin Invest. 2014; 124:580-591.
-
(2014)
J Clin Invest.
, vol.124
, pp. 580-591
-
-
Bluteau, D.1
Balduini, A.2
Balayn, N.3
Currao, M.4
Nurden, P.5
Deswarte, C.6
Leverger, G.7
Noris, P.8
Perrotta, S.9
Solary, E.10
Vainchenker, W.11
Debili, N.12
Favier, R.13
Raslova, H.14
-
49
-
-
84886735653
-
Identification and characterization of an alternative splice variant of Mpl with a high affinity for TPO and its activation of ERK1/2 signaling
-
Wang Q, Sun R, Wu L, Huang J, Wang P, Yuan H, Qiu F, Xu X, Wu D, Yu Y, Liu X, Zhang Q. Identification and characterization of an alternative splice variant of Mpl with a high affinity for TPO and its activation of ERK1/2 signaling. Int J Biochem Cell Biol. 2013; 45:2852-2863.
-
(2013)
Int J Biochem Cell Biol.
, vol.45
, pp. 2852-2863
-
-
Wang, Q.1
Sun, R.2
Wu, L.3
Huang, J.4
Wang, P.5
Yuan, H.6
Qiu, F.7
Xu, X.8
Wu, D.9
Yu, Y.10
Liu, X.11
Zhang, Q.12
-
50
-
-
84869192963
-
Molecular prognostic factors in cytogenetically normal acute myeloid leukemia
-
Walker A, Marcucci G. Molecular prognostic factors in cytogenetically normal acute myeloid leukemia. Expert Rev Hematol. 2012; 5:547-558.
-
(2012)
Expert Rev Hematol.
, vol.5
, pp. 547-558
-
-
Walker, A.1
Marcucci, G.2
-
51
-
-
80755189307
-
Pediatric high-grade glioma: identification of poly(ADP-ribose) polymerase as a potential therapeutic target
-
Smith SJ, Long A, Barrow JH, Macarthur DC, Coyle B, Grundy RG. Pediatric high-grade glioma: identification of poly(ADP-ribose) polymerase as a potential therapeutic target. Neuro Oncol. 2011; 13:1171-1177.
-
(2011)
Neuro Oncol.
, vol.13
, pp. 1171-1177
-
-
Smith, S.J.1
Long, A.2
Barrow, J.H.3
Macarthur, D.C.4
Coyle, B.5
Grundy, R.G.6
-
52
-
-
0038541808
-
Incidence and prognostic significance of C-MPL expression in acute myeloid leukemia
-
Chelvatheebam S, Langabeer SE, Linch DC, Hills RK, Greenwell P. Incidence and prognostic significance of C-MPL expression in acute myeloid leukemia. Leuk Res. 2003; 27:869-870.
-
(2003)
Leuk Res.
, vol.27
, pp. 869-870
-
-
Chelvatheebam, S.1
Langabeer, S.E.2
Linch, D.C.3
Hills, R.K.4
Greenwell, P.5
-
53
-
-
80355135233
-
PARP inhibitors in breast cancer: BRCA and beyond
-
Rios J, Puhalla S. PARP inhibitors in breast cancer: BRCA and beyond. Oncology (Williston Park). 2011; 25:1014-1025.
-
(2011)
Oncology (Williston Park).
, vol.25
, pp. 1014-1025
-
-
Rios, J.1
Puhalla, S.2
-
54
-
-
77954032829
-
Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval
-
Fong PC, Yap TA, Boss DS, Carden CP, Mergui-Roelvink M, Gourley C, De Greve J, Lubinski J, Shanley S, Messiou C, A'Hern R, Tutt A, Ashworth A, Stone J, Carmichael J, Schellens JH, et al. Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval. J Clin Oncol. 2010; 28:2512-2519.
-
(2010)
J Clin Oncol.
, vol.28
, pp. 2512-2519
-
-
Fong, P.C.1
Yap, T.A.2
Boss, D.S.3
Carden, C.P.4
Mergui-Roelvink, M.5
Gourley, C.6
De Greve, J.7
Lubinski, J.8
Shanley, S.9
Messiou, C.10
A'Hern, R.11
Tutt, A.12
Ashworth, A.13
Stone, J.14
Carmichael, J.15
Schellens, J.H.16
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