Identification of small molecule inhibitors of Zcchc11 TUTase activity

RNA Biology

Volumn 12, Issue 8, 2015, Pages 792-800

  Lin, Shuibin ^a,b   Gregory, Richard I ^a,b,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

Cancer; Let 7; Lin28; MicroRNA; MiRNA; TUT4; TUTase; Uridylation; Zcchc11

Indexed keywords

ENZYME INHIBITOR; HEXOSE 1 PHOSPHATE URIDYLYLTRANSFERASE; POLYURIDYLIC ACID; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ZCCHC11 ENZYME; DNA BINDING PROTEIN; LIN-28 PROTEIN, HUMAN; MICRORNA; MIRNLET7 MICRORNA, HUMAN; MOLECULAR LIBRARY; RECOMBINANT PROTEIN; RNA BINDING PROTEIN; RNA POLYMERASE; RNA PRECURSOR; URIDINE; UTP-RNA URIDYLYLTRANSFERASE; ZCCHC11 PROTEIN, HUMAN;

ARTICLE; BIOCHEMICAL ANALYSIS; DRUG IDENTIFICATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PURIFICATION; EXPRESSION VECTOR; HIGH THROUGHPUT SCREENING; IN VITRO STUDY; LUCIFERASE ASSAY; MOLECULAR LIBRARY; RADIOACTIVITY; REAL TIME POLYMERASE CHAIN REACTION; ZINC FINGER MOTIF; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; PHARMACOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

DNA-BINDING PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; HEK293 CELLS; HUMANS; MICRORNAS; MOLECULAR STRUCTURE; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA NUCLEOTIDYLTRANSFERASES; RNA PRECURSORS; RNA-BINDING PROTEINS; SMALL MOLECULE LIBRARIES; URIDINE;

EID: 84944446155     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.1080/15476286.2015.1058478     Document Type: Article

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